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Molecular Mechanisms of RET Activation in Human Cancer.
- Published in:
- Annals of the New York Academy of Sciences, 2002, v. 963, n. 1, p. 116, doi. 10.1111/j.1749-6632.2002.tb04102.x
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- Article
HMGA1 and HMGA2 protein expression in mouse spermatogenesis.
- Published in:
- Oncogene, 2002, v. 21, n. 22, p. 3644, doi. 10.1038/sj.onc.1205501
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- Publication type:
- Article
Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas.
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- Oncogene, 2002, v. 21, n. 20, p. 3190, doi. 10.1038/sj.onc.1205428
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- Article
Thyroid cell transformation requires the expression of the HMGA1 proteins.
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- Oncogene, 2002, v. 21, n. 19, p. 2971, doi. 10.1038/sj.onc.1205368
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- Publication type:
- Article
Glial cell line-derived neurotrophic factor induces proliferative inhibition of NT2/D1 cells through RET-mediated up-regulation of the cyclin-dependent kinase inhibitor p27[sup kip1].
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- Oncogene, 2002, v. 21, n. 11, p. 1739, doi. 10.1038/sj.onc.1205226
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- Publication type:
- Article
RET/PTC1 oncogene signaling in PC Cl 3 thyroid cells requires the small GTP-binding protein Rho.
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- Oncogene, 2001, v. 20, n. 48, p. 6973, doi. 10.1038/sj.onc.1204886
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- Article
High mobility group I (Y) proteins bind HIPK2, a serine-threonine kinase protein which inhibits cell growth.
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- Oncogene, 2001, v. 20, n. 43, p. 6132, doi. 10.1038/sj.onc.1204635
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- Publication type:
- Article
Expression and alternative splicing of c-ret RNA in papillary thyroid carcinomas.
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- Oncogene, 2001, v. 20, n. 7, p. 885, doi. 10.1038/sj.onc.1204161
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- Publication type:
- Article
The RFG oligomerization domain mediates kinase activation and re-localization of the RET/PTC3 oncoprotein to the plasma membrane.
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- Oncogene, 2001, v. 20, n. 5, p. 599, doi. 10.1038/sj.onc.1204127
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- Article
The insulin receptor substrate (IRS)-1 recruits phosphatidylinositol 3-kinase to Ret: evidence for a competition between Shc and IRS-1 for the binding to Ret.
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- Oncogene, 2001, v. 20, n. 2, p. 209, doi. 10.1038/sj.onc.1204049
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- Article
The TRK-T1 fusion protein induces neoplastic transformation of thyroid epithelium.
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- Oncogene, 2000, v. 19, n. 50, p. 5729, doi. 10.1038/sj.onc.1203922
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- Publication type:
- Article
PTEN expression is reduced in a subset of sporadic thyroid carcinomas: evidence that PTEN-growth suppressing activity in thyroid cancer cells is mediated by p27<sup>kip1</sup>.
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- Oncogene, 2000, v. 19, n. 28, p. 3146, doi. 10.1038/sj.onc.1203633
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- Article
Key role of the cyclin-dependent kinase inhibitor p27<sup>kip1</sup> for embryonal carcinoma cell survival and differentiation.
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- Oncogene, 1999, v. 18, n. 46, p. 6241, doi. 10.1038/sj.onc.1203031
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- Publication type:
- Article
Modulation of in vivo growth of thyroid tumor-derived cell lines by sense and antisense vascular endothelial growth factor gene.
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- Oncogene, 1999, v. 18, n. 34, p. 4860, doi. 10.1038/sj.onc.1202869
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- Publication type:
- Article
Dual effect on the RET receptor of MEN 2 mutations affecting specific extracytoplasmic cysteines.
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- Oncogene, 1998, v. 17, n. 22, p. 2851, doi. 10.1038/sj.onc.1202202
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- Article
Truncated and chimeric HMGI-C genes induce neoplastic transformation of NIH3T3 murine fibroblasts.
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- Oncogene, 1998, v. 17, n. 4, p. 413, doi. 10.1038/sj.onc.1201952
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- Article
Increase in AP-1 activity is a general event in thyroid cell transformation in vitro and in vivo.
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- Oncogene, 1998, v. 17, n. 3, p. 377, doi. 10.1038/sj.onc.1201953
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- Publication type:
- Article
Signalling of the Ret receptor tyrosine kinase through the c-Jun NH<sub>2</sub>-terminal protein kinases (JNKs): evidence for a divergence of the ERKs and JNKs pathways induced by Ret.
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- Oncogene, 1998, v. 16, n. 19, p. 2435, doi. 10.1038/sj.onc.1201778
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- Article
Upregulation of the angiogenic factors PlGF, VEGF and their receptors (Flt-1, Flk-1/KDR) by TSH in cultured thyrocytes and in the thyroid gland of thiouracil-fed rats suggest a TSH-dependent paracrine mechanism for goiter hypervascularization.
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- Oncogene, 1997, v. 15, n. 22, p. 2687, doi. 10.1038/sj.onc.1201456
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- Article
Expression of the neoplastic phenotype by human thyroid carcinoma cell lines requires NFκB p65 protein expression.
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- Oncogene, 1997, v. 15, n. 16, p. 1987, doi. 10.1038/sj.onc.1201373
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- Publication type:
- Article
Establishment of a non-tumorigenic papillary thyroid cell line (FB-2) carrying the RET/PTC1 rearrangement.
- Published in:
- International Journal of Cancer, 2002, v. 97, n. 5, p. 608, doi. 10.1002/ijc.10116
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- Article
High mobility group HMGI(Y) protein expression in human colorectal hyperplastic and neoplastic diseases.
- Published in:
- International Journal of Cancer, 2001, v. 91, n. 2, p. 147, doi. 10.1002/1097-0215(200002)9999:9999<::AID-IJC1033>3.0.CO;2-V
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- Publication type:
- Article
Potentiation of the malignant phenotype of the undifferentiated ARO thyroid cell line by insertion of the bcl-2 gene.
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- International Journal of Cancer, 1999, v. 81, n. 6, p. 956, doi. 10.1002/(SICI)1097-0215(19990611)81:6<956::AID-IJC19>3.0.CO;2-N
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- Publication type:
- Article
Double knock-out of Hmga1 and Hipk2 genes causes perinatal death associated to respiratory distress and thyroid abnormalities in mice.
- Published in:
- Cell Death & Disease, 2019, v. 10, n. 10, p. N.PAG, doi. 10.1038/s41419-019-1975-5
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- Publication type:
- Article
The Phosphotyrosine Phosphatase η Mediates Somatostatin Inhibition of Glioma Proliferation via the Dephosphorylation of ERK½.
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- Annals of the New York Academy of Sciences, 2004, v. 1030, n. 1, p. 264, doi. 10.1196/annals.1329.033
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- Publication type:
- Article
The lncRNA RMST is drastically downregulated in anaplastic thyroid carcinomas where exerts a tumor suppressor activity impairing epithelial-mesenchymal transition and stemness.
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- Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01514-x
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- Article
Reduced E-cadherin expression contributes to the loss of p27<sup>kip1</sup>-mediated mechanism of contact inhibition in thyroid anaplastic carcinomas.
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- Carcinogenesis, 2005, v. 26, n. 6, p. 1021, doi. 10.1093/carcin/bgi050
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- Article
Restoration of receptor-type protein tyrosine phosphatase ? function inhibits human pancreatic carcinoma cell growth in vitro and in vivo.
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- Carcinogenesis, 2004, v. 25, n. 11, p. 2107, doi. 10.1093/carcin/bgh224
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- Article
A truncated HMGA1 gene induces proliferation of the 3T3-L1 pre-adipocytic cells: a model of human lipomas.
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- Carcinogenesis, 2003, v. 24, n. 12, p. 1861
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- Article
Role of the high mobility group A proteins in human lipomas.
- Published in:
- Carcinogenesis, 2001, v. 22, n. 10, p. 1583, doi. 10.1093/carcin/22.10.1583
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- Article
HMGI-C gene expression is not required for in vivo thyroid cell transformation.
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- Carcinogenesis, 2001, v. 22, n. 2, p. 251, doi. 10.1093/carcin/22.2.251
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- Article
Functional Variants of the HMGA1 Gene and Type 2 Diabetes Mellitus.
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- JAMA: Journal of the American Medical Association, 2011, v. 305, n. 9, p. 903, doi. 10.1001/jama.2011.207
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- Article
Neoplastic transformation of rat thyroid cells requires the junB and fra-1 gene induction which is dependent on the HMGI-C gene product.
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- EMBO Journal, 1997, v. 16, n. 17, p. 5310, doi. 10.1093/emboj/16.17.5310
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- Article
Identifying Methylation Patterns in Dental Pulp Aging: Application to Age-at-Death Estimation in Forensic Anthropology.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 7, p. 3717, doi. 10.3390/ijms22073717
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- Article
Analysis of mir-9 Expression Pattern in Rat Retina during Postnatal Development.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2577, doi. 10.3390/ijms22052577
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- Article
A KRAB zinc finger protein gene is the potential target of 19q13 translocation in benign thyroid tumors.
- Published in:
- Genes, Chromosomes & Cancer, 1999, v. 26, n. 3, p. 229, doi. 10.1002/(SICI)1098-2264(199911)26:3<229::AID-GCC7>3.0.CO;2-J
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- Article
Involvement of the HMGI(Y) gene in a microfollicular adenoma of the thyroid.
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- Genes, Chromosomes & Cancer, 1999, v. 24, n. 3, p. 286, doi. 10.1002/(SICI)1098-2264(199903)24:3<286::AID-GCC16>3.0.CO;2-E
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- Publication type:
- Article
HMGIY is the target of 6p21.3 rearrangements in various benign mesenchymal tumors.
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- Genes, Chromosomes & Cancer, 1998, v. 23, n. 4, p. 279, doi. 10.1002/(SICI)1098-2264(199812)23:4<279::AID-GCC1>3.0.CO;2-1
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- Publication type:
- Article
Breakpoints of 19q13 translocations of benign thyroid tumors map within a 400 kilobase region.
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- Genes, Chromosomes & Cancer, 1997, v. 20, n. 2, p. 201, doi. 10.1002/(SICI)1098-2264(199710)20:2<201::AID-GCC11>3.0.CO;2-T
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- Article
UbcH10 overexpression is less pronounced in older colorectal cancer patients.
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- 2016
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- Publication type:
- Letter
HMGA1 protein expression sensitizes cells to cisplatin-induced cell death.
- Published in:
- Oncogene, 2005, v. 24, n. 45, p. 6809, doi. 10.1038/sj.onc.1208831
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- Publication type:
- Article
Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.
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- Oncogene, 2005, v. 24, n. 21, p. 3427, doi. 10.1038/sj.onc.1208501
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- Article
The rat tyrosine phosphatase?increases cell adhesion by activating c-Src through dephosphorylation of its inhibitory phosphotyrosine residue.
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- Oncogene, 2005, v. 24, n. 19, p. 3187, doi. 10.1038/sj.onc.1208510
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- Article
Loss of the tumor suppressor gene PTEN marks the transition from intratubular germ cell neoplasias (ITGCN) to invasive germ cell tumors.
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- Oncogene, 2005, v. 24, n. 11, p. 1882, doi. 10.1038/sj.onc.1208368
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- Article
The tyrosine phosphatase PTPRJ/DEP-1 genotype affects thyroid carcinogenesis.
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- Oncogene, 2004, v. 23, n. 52, p. 8432, doi. 10.1038/sj.onc.1207766
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- Article
Disease associated mutations at valine 804 in the RET receptor tyrosine kinase confer resistance to selective kinase inhibitors.
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- Oncogene, 2004, v. 23, n. 36, p. 6056, doi. 10.1038/sj.onc.1207810
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- Article
Functional expression of the CXCR4 chemokine receptor is induced by RET/PTC oncogenes and is a common event in human papillary thyroid carcinomas.
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- Oncogene, 2004, v. 23, n. 35, p. 5958, doi. 10.1038/sj.onc.1207790
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- Article
Autocrine stimulation by osteopontin plays a pivotal role in the expression of the mitogenic and invasive phenotype of RET/PTC-transformed thyroid cells.
- Published in:
- Oncogene, 2004, v. 23, n. 12, p. 2188, doi. 10.1038/sj.onc.1207322
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- Article
Critical role of cyclin D3 in TSH-dependent growth of thyrocytes and in hyperproliferative diseases of the thyroid gland.
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- Oncogene, 2003, v. 22, n. 48, p. 7576, doi. 10.1038/sj.onc.1207055
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- Article
Cloning and molecular characterization of a novel gene strongly induced by the adenovirus E1A gene in rat thyroid cells.
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- Oncogene, 2003, v. 22, n. 7, p. 1087, doi. 10.1038/sj.onc.1206194
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- Publication type:
- Article