Works by FLASHMAN, Emily

Results: 20

Lysine‐241 Has a Role in Coupling 2OG Turnover with Substrate Oxidation During KDM4‐Catalysed Histone Demethylation.

Published in:

ChemBioChem, 2018, v. 19, n. 9, p. 917, doi. 10.1002/cbic.201800002

By:

Hancock, Rebecca L.;
Abboud, Martine I.;
Smart, Tristan J.;
Flashman, Emily;
Kawamura, Akane;
Schofield, Christopher J.;
Hopkinson, Richard J.

Publication type:

Article

Targeting plant cysteine oxidase activity for improved submergence tolerance.

Published in:

Plant Journal, 2022, v. 109, n. 4, p. 779, doi. 10.1111/tpj.15605

By:

Taylor‐Kearney, Leah J.;
Flashman, Emily

Publication type:

Article

Measuring plant cysteine oxidase interactions with substrates using intrinsic tryptophan fluorescence.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-83508-y

By:

Gunawardana, Dona M.;
Southern, Daisy A.;
Flashman, Emily

Publication type:

Article

Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen.

Published in:

FEBS Journal, 2010, v. 277, n. 19, p. 4089, doi. 10.1111/j.1742-4658.2010.07804.x

By:

Flashman, Emily;
Hoffart, Lee M.;
Hamed, Refaat B.;
Bollinger, Jr., J. Martin;
Krebs, Carsten;
Schofield, Christopher J.

Publication type:

Article

Evidence for a Stereoelectronic Effect in Human Oxygen Sensing.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 10, p. 1784, doi. 10.1002/anie.200805427

By:

Loenarz, Christoph;
Mecinović, Jasmin;
Chowdhury, Rasheduzzaman;
McNeill, Luke A.;
Flashman, Emily;
Schofield, Christopher J.

Publication type:

Article

Dynamic states of the DNA repair enzyme AlkB regulate product release.

Published in:

EMBO Reports, 2008, v. 9, n. 9, p. 872, doi. 10.1038/embor.2008.120

By:

Bleijlevens, Boris;
Shivarattan, Tara;
Flashman, Emily;
Yang, Yi;
Simpson, Pete J;
Koivisto, Pertti;
Sedgwick, Barbara;
Schofield, Christopher J;
Matthews, Steve J

Publication type:

Article

Plant cysteine oxidases are dioxygenases that directly enable arginyl transferase-catalysed arginylation of N-end rule targets.

Published in:

Nature Communications, 2017, v. 8, n. 3, p. 14690, doi. 10.1038/ncomms14690

By:

White, Mark D.;
Klecker, Maria;
Hopkinson, Richard J.;
Weits, Daan A.;
Mueller, Carolin;
Naumann, Christin;
O'Neill, Rebecca;
Wickens, James;
Yang, Jiayu;
Brooks-Bartlett, Jonathan C.;
Garman, Elspeth F.;
Grossmann, Tom N.;
Dissmeyer, Nico;
Flashman, Emily

Publication type:

Article

Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases.

Published in:

Nature Communications, 2014, v. 5, n. 3, p. 3423, doi. 10.1038/ncomms4423

By:

Tarhonskaya, Hanna;
Rydzik, Anna M.;
Leung, Ivanhoe K. H.;
Loik, Nikita D.;
Chan, Mun Chiang;
Kawamura, Akane;
McCullagh, James S. O.;
Claridge, Timothy D. W.;
Flashman, Emily;
Schofield, Christopher J.

Publication type:

Article

ESI-MS Studies on Prolyl Hydroxylase Domain 2 Reveal a New Metal Binding Site.

Published in:

ChemMedChem, 2008, v. 3, n. 4, p. 569, doi. 10.1002/cmdc.200700233

By:

Mecinović, Jasmin;
Chowdhury, Rasheduzzaman;
Liénard, Benoît M. R.;
Flashman, Emily;
Buck, Matthew R. G.;
Oldham, Neil J.;
Schofield, Christopher J.

Publication type:

Article

Cover Picture: ESI-MS Studies on Prolyl Hydroxylase Domain 2 Reveal a New Metal Binding Site (ChemMedChem 4/2008).

Published in:

ChemMedChem, 2008, v. 3, n. 4, p. 509, doi. 10.1002/cmdc.200890014

By:

Mecinović, Jasmin;
Chowdhury, Rasheduzzaman;
Liénard, Benoît M. R.;
Flashman, Emily;
Buck, Matthew R. G.;
Oldham, Neil J.;
Schofield, Christopher J.

Publication type:

Article

Destined for destruction: The role of methionine aminopeptidases and plant cysteine oxidases in N-degron formation.

Published in:

Plant Physiology, 2025, v. 197, n. 1, p. 1, doi. 10.1093/plphys/kiae667

By:

Fuentes-Terrón, Andrea;
Latter, Rebecca;
Madden, Samuel;
Manrique-Gil, Isabel;
Estrada, Jessenia;
Arteaga, Noelia;
Sánchez-Vicente, Inmaculada;
Lorenzo, Oscar;
Flashman, Emily

Publication type:

Article

Zinc Excess Induces a Hypoxia-Like Response by Inhibiting Cysteine Oxidases in Poplar Roots.

Published in:

Plant Physiology, 2019, v. 180, n. 3, p. 1614, doi. 10.1104/pp.18.01458

By:

Carbonare, Laura Dalle;
White, Mark D.;
Shukla, Vinay;
Francini, Alessandra;
Perata, Pierdomenico;
Flashman, Emily;
Sebastiani, Luca;
Licausi, Francesco

Publication type:

Article

YcfD<sub>RM</sub> is a thermophilic oxygen-dependent ribosomal protein uL16 oxygenase.

Published in:

Extremophiles, 2018, v. 22, n. 3, p. 553, doi. 10.1007/s00792-018-1016-9

By:

Sekirnik, Rok;
Wilkins, Sarah E.;
Bush, Jacob;
Tarhonskaya, Hanna;
Münzel, Martin;
Hussein, Aayan;
Flashman, Emily;
Mohammed, Shabaz;
McDonough, Michael A.;
Loenarz, Christoph;
Schofield, Christopher J.

Publication type:

Article

Investigating the contribution of the active site environment to the slow reaction of hypoxia-inducible factor prolyl hydroxylase domain 2 with oxygen.

Published in:

Biochemical Journal, 2014, v. 463, n. 3, p. 363, doi. 10.1042/BJ20140779

By:

TARHONSKAYA, Hanna;
CHOWDHURY, Rasheduzzaman;
LEUNG, Ivanhoe K. H.;
LOIK, Nikita D.;
MCCULLAGH, James S. O.;
CLARIDGE, Timothy D. W.;
SCHOFIELD, Christopher J.;
FLASHMAN, Emily

Publication type:

Article

Investigations on the oxygen dependence of a 2-oxoglutarate histone demethylase.

Published in:

Biochemical Journal, 2013, v. 449, n. 2, p. 491, doi. 10.1042/BJ20121155

By:

SÁNCHEZ-FERNÁNDEZ, Elena M.;
TARHONSKAYA, Hanna;
AL-QAHTANI, Khalid;
HOPKINSON, Richard J.;
MCCULLAGH, James S. O.;
SCHOFIELD, Christopher J.;
FLASHMAN, Emily

Publication type:

Article

The most versatile of all reactive intermediates?

Published in:

Nature Chemical Biology, 2007, v. 3, n. 2, p. 86, doi. 10.1038/nchembio0207-86

By:

Flashman, Emily;
Schofield, Christopher J.

Publication type:

Article

Biochemical characterization of New Delhi metallo-β-lactamase variants reveals differences in protein stability.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2015, v. 70, n. 2, p. 463, doi. 10.1093/jac/dku403

By:

Makena, Anne;
Brem, Jürgen;
Pfeffer, Inga;
Geffen, Rebecca E. J.;
Wilkins, Sarah E.;
Tarhonskaya, Hanna;
Flashman, Emily;
Phee, Lynette M.;
Wareham, David W.;
Schofield, Christopher J.

Publication type:

Article

Oxygen-dependent proteolysis regulates the stability of angiosperm polycomb repressive complex 2 subunit VERNALIZATION 2.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07875-7

By:

Gibbs, Daniel J.;
Tedds, Hannah M.;
Labandera, Anne-Marie;
Bailey, Mark;
White, Mark D.;
Hartman, Sjon;
Sprigg, Colleen;
Mogg, Sophie L.;
Osborne, Rory;
Dambire, Charlene;
Boeckx, Tinne;
Paling, Zachary;
Voesenek, Laurentius A. C. J.;
Flashman, Emily;
Holdsworth, Michael J.

Publication type:

Article

Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications.

Published in:

Epigenetics, 2021, v. 16, n. 1, p. 14, doi. 10.1080/15592294.2020.1786305

By:

Hsu, Kuo-Feng;
Wilkins, Sarah E.;
Hopkinson, Richard J.;
Sekirnik, Rok;
Flashman, Emily;
Kawamura, Akane;
McCullagh, James S.O.;
Walport, Louise J.;
Schofield, Christopher J.

Publication type:

Article

Emerging roles for thiol dioxygenases as oxygen sensors.

Published in:

FEBS Journal, 2022, v. 289, n. 18, p. 5426, doi. 10.1111/febs.16147

By:

Gunawardana, Dona M.;
Heathcote, Karen C.;
Flashman, Emily

Publication type:

Article