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VCE-004.3, a cannabidiol aminoquinone derivative, prevents bleomycin-induced skin fibrosis and inflammation through PPARγ- and CB<sub>2</sub> receptor-dependent pathways.
- Published in:
- 2018
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- Publication type:
- journal article
Cannabinoid-dopamine interactions in the physiology and physiopathology of the basal ganglia.
- Published in:
- 2016
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- Publication type:
- journal article
Prospects for cannabinoid therapies in basal ganglia disorders.
- Published in:
- 2011
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- Publication type:
- journal article
The endocannabinoid system as a target for the treatment of motor dysfunction.
- Published in:
- 2009
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- Publication type:
- journal article
Region-dependent changes in endocannabinoid transmission in the brain of morphine-dependent rats.
- Published in:
- 2003
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- Publication type:
- journal article
Recent advances in the pathogenesis and therapeutics of amyotrophic lateral sclerosis.
- Published in:
- 2021
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- Publication type:
- editorial
Δ<sup>9</sup> -Tetrahydrocannabinolic acid alleviates collagen-induced arthritis: Role of PPARγ and CB<sub>1</sub> receptors.
- Published in:
- 2020
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- Publication type:
- journal article
Prenatal Exposure to Methamphetamine in the Rat.
- Published in:
- Annals of the New York Academy of Sciences, 2002, v. 965, n. 1, p. 68, doi. 10.1111/j.1749-6632.2002.tb04152.x
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- Publication type:
- Article
Neonatal Methamphetamine in the Rat: Evidence for Gender-specific Differences upon Tyrosine Hydroxylase Enzyme in the Dopaminergic Nigrostriatal System.
- Published in:
- Annals of the New York Academy of Sciences, 2000, v. 914, n. 1, p. 431, doi. 10.1111/j.1749-6632.2000.tb05217.x
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- Publication type:
- Article
A Transitional Year Level to Higher Education: Challenges, Experiences and Self-regulatory Strategies during the Final Year of the University Preparatory Level.
- Published in:
- Estudios Sobre Educacion, 2020, v. 39, p. 109, doi. 10.15581/004.39.109-133
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- Publication type:
- Article
Analysis of endocannabinoid signaling elements and related proteins in lymphocytes of patients with Dravet syndrome.
- Published in:
- Pharmacology Research & Perspectives, 2016, v. 4, n. 2, p. n/a, doi. 10.1002/prp2.220
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- Publication type:
- Article
The cannabinoid quinol VCE-004.8 alleviates bleomycin-induced scleroderma and exerts potent antifibrotic effects through peroxisome proliferator-activated receptor-γ and CB2 pathways.
- Published in:
- Scientific Reports, 2016, p. 21703, doi. 10.1038/srep21703
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- Publication type:
- Article
The Cannabigerol Derivative VCE-003.2 Exerts Therapeutic Effects in 6-Hydroxydopamine-Lesioned Mice: Comparison with The Classic Dopaminergic Replacement Therapy.
- Published in:
- Brain Sciences (2076-3425), 2023, v. 13, n. 9, p. 1272, doi. 10.3390/brainsci13091272
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- Publication type:
- Article
The biomedical challenge of neurodegenerative disorders: an opportunity for cannabinoid‐based therapies to improve on the poor current therapeutic outcomes.
- Published in:
- British Journal of Pharmacology, 2019, v. 176, n. 10, p. 1370, doi. 10.1111/bph.14382
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- Publication type:
- Article
The biomedical challenge of neurodegenerative disorders: an opportunity for cannabinoid-based therapies to improve on the poor current therapeutic outcomes.
- Published in:
- 2018
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- Publication type:
- journal article
Changes in CB<sub>1</sub> and CB<sub>2</sub> receptors in the post-mortem cerebellum of humans affected by spinocerebellar ataxias.
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- British Journal of Pharmacology, 2014, v. 171, n. 6, p. 1472, doi. 10.1111/bph.12283
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- Publication type:
- Article
Changes in CB(1) and CB(2) receptors in the post-mortem cerebellum of humans affected by spinocerebellar ataxias.
- Published in:
- 2014
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- Publication type:
- journal article
Neuropathological Characterization of a Dravet Syndrome Knock-In Mouse Model Useful for Investigating Cannabinoid Treatments.
- Published in:
- Frontiers in Molecular Neuroscience, 2021, v. 13, p. N.PAG, doi. 10.3389/fnmol.2020.602801
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- Publication type:
- Article
Acyl-based anandamide uptake inhibitors cause rapid toxicity to C6 glioma cells at pharmacologically relevant concentrations.
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- Journal of Neurochemistry, 2006, v. 99, n. 2, p. 677, doi. 10.1111/j.1471-4159.2006.04104.x
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- Publication type:
- Article
Effects of Neonatal Exposure to Methamphetamine: Catecholamine Levels in Brain Areas of the Developing Rat.
- Published in:
- Annals of the New York Academy of Sciences, 2004, v. 1025, n. 1, p. 602, doi. 10.1196/annals.1316.075
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- Publication type:
- Article
Decreased Cannabinoid CB1 Receptor mRNA Levels and Immunoreactivity in Pituitary Tumors Induced by Prolonged Exposure to Estrogens.
- Published in:
- Pituitary, 2000, v. 3, n. 4, p. 221, doi. 10.1023/A:1012874029689
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- Publication type:
- Article
Preclinical Investigation in Neuroprotective Effects of the GPR55 Ligand VCE-006.1 in Experimental Models of Parkinson's Disease and Amyotrophic Lateral Sclerosis.
- Published in:
- Molecules, 2021, v. 26, n. 24, p. 7643, doi. 10.3390/molecules26247643
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- Publication type:
- Article
Neuroprotection with the Cannabidiol Quinone Derivative VCE-004.8 (EHP-101) against 6-Hydroxydopamine in Cell and Murine Models of Parkinson's Disease.
- Published in:
- Molecules, 2021, v. 26, n. 11, p. 3245, doi. 10.3390/molecules26113245
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- Publication type:
- Article
Development of An Oral Treatment with the PPAR-γ-Acting Cannabinoid VCE-003.2 Against the Inflammation-Driven Neuronal Deterioration in Experimental Parkinson's Disease.
- Published in:
- Molecules, 2019, v. 24, n. 15, p. 2702, doi. 10.3390/molecules24152702
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- Publication type:
- Article
Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington's disease.
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- Journal of Neuroscience Research, 2011, v. 89, n. 9, p. 1509, doi. 10.1002/jnr.22682
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- Publication type:
- Article
Endocannabinoid System in Spinocerebellar Ataxia Type-3 and Other Autosomal-Dominant Cerebellar Ataxias: Potential Role in Pathogenesis and Expected Relevance as Neuroprotective Targets.
- Published in:
- Frontiers in Molecular Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnmol.2019.00094
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- Publication type:
- Article
Analysis of cannabinoid receptor binding and mRNA expression and endogenous cannabinoid contents in the developing rat brain during late gestation and early postnatal period.
- Published in:
- Synapse, 1999, v. 33, n. 3, p. 181, doi. 10.1002/(SICI)1098-2396(19990901)33:3<181::AID-SYN3>3.0.CO;2-R
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- Publication type:
- Article
BiP Heterozigosity Aggravates Pathological Deterioration in Experimental Amyotrophic Lateral Sclerosis.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 22, p. 12533, doi. 10.3390/ijms222212533
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- Publication type:
- Article
Effects of a Sativex-Like Combination of Phytocannabinoids on Disease Progression in R6/2 Mice, an Experimental Model of Huntington’s Disease.
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- International Journal of Molecular Sciences, 2017, v. 18, n. 4, p. 684, doi. 10.3390/ijms18040684
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- Publication type:
- Article
Preface: Cannabinoids as New Tools for the Treatment of Neurological Disorders.
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- Molecular Neurobiology, 2007, v. 36, n. 1, p. 1, doi. 10.1007/s12035-007-8005-9
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- Publication type:
- Article
Cannabinoids and Neuroprotection in Basal Ganglia Disorders.
- Published in:
- Molecular Neurobiology, 2007, v. 36, n. 1, p. 82, doi. 10.1007/s12035-007-0004-3
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- Publication type:
- Article
Description of a Bivalent Cannabinoid Ligand with Hypophagic Properties.
- Published in:
- Archiv der Pharmazie, 2013, v. 346, n. 3, p. 171, doi. 10.1002/ardp.201200392
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- Publication type:
- Article
Acute Effects of Δ<sup>9-</sup>Tetrahydrocannabinol on Tuberoinfundibular Dopamine Activity, Anterior Pituitary Sensitivity to Dopamine and Prolactin Release Vary as a Function of Estrous Cycle.
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- Neuroendocrinology, 1993, v. 58, n. 3, p. 280, doi. 10.1159/000126551
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- Publication type:
- Article
Cannabinoid–Dopamine Interaction in the Pathophysiology and Treatment of CNS Disorders.
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- CNS Neuroscience & Therapeutics, 2010, v. 16, n. 3, p. e72, doi. 10.1111/j.1755-5949.2010.00144.x
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- Publication type:
- Article
Targeting Cannabinoid CB<sub>2</sub> Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders.
- Published in:
- Frontiers in Neuroscience, 2016, p. 1, doi. 10.3389/fnins.2016.00406
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- Publication type:
- Article
Morphine self-administration alters the expression of translational machinery genes in the amygdala of male Lewis rats.
- Published in:
- 2019
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- Publication type:
- journal article
Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's disease.
- Published in:
- Journal of Neurochemistry, 2003, v. 84, n. 5, p. 1097, doi. 10.1046/j.1471-4159.2003.01595.x
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- Publication type:
- Article
Blockade of cannabinoid CB[sub 1] receptor function protects againstin vivo disseminating brain damage following NMDA-induced excitotoxicity.
- Published in:
- Journal of Neurochemistry, 2002, v. 82, n. 1, p. 154, doi. 10.1046/j.1471-4159.2002.00961.x
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- Publication type:
- Article
Discovery of Homobivalent Bitopic Ligands of the Cannabinoid CB<sub>2</sub> Receptor**.
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- Chemistry - A European Journal, 2020, v. 26, n. 68, p. 15839, doi. 10.1002/chem.202003389
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- Publication type:
- Article
Structure–Effect Relationships of Novel Semi-Synthetic Cannabinoid Derivatives.
- Published in:
- Frontiers in Pharmacology, 2019, v. 10, p. 1, doi. 10.3389/fphar.2019.01284
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- Publication type:
- Article
Changes in Endocannabinoid Receptors and Enzymes in the Spinal Cord of SOD1<sup>G93A</sup> Transgenic Mice and Evaluation of a Sativex<sup>®</sup>-like Combination of Phytocannabinoids: Interest for Future Therapies in Amyotrophic Lateral Sclerosis
- Published in:
- CNS Neuroscience & Therapeutics, 2014, v. 20, n. 9, p. 809, doi. 10.1111/cns.12262
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- Publication type:
- Article
A double-blind, randomized, cross-over, placebo-controlled, pilot trial with Sativex in Huntington's disease.
- Published in:
- Journal of Neurology, 2016, v. 263, n. 7, p. 1390, doi. 10.1007/s00415-016-8145-9
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- Publication type:
- Article
Combining rimonabant and fentanyl in a single entity: preparation and pharmacological results.
- Published in:
- Drug Design, Development & Therapy, 2014, v. 8, p. 263, doi. 10.2147/DDDT.S55045
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- Publication type:
- Article
Combining rimonabant and fentanyl in a single entity: preparation and pharmacological results.
- Published in:
- Drug Design, Development & Therapy, 2014, v. 8, p. 263, doi. 10.2147/DDDT.S55045
- By:
- Publication type:
- Article
The endocannabinoid system is altered in the post-mortem prefrontal cortex of alcoholic subjects.
- Published in:
- Addiction Biology, 2015, v. 20, n. 4, p. 773, doi. 10.1111/adb.12160
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- Publication type:
- Article
Different Susceptibility to the Parkinson's Toxin MPTP in Mice Lacking the Redox Master Regulator Nrf2 or Its Target Gene Heme Oxygenase-1.
- Published in:
- PLoS ONE, 2010, v. 5, n. 7, p. 1, doi. 10.1371/journal.pone.0011838
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- Publication type:
- Article
A53T-Alpha-Synuclein Overexpression Impairs Dopamine Signaling and Striatal Synaptic Plasticity in Old Mice.
- Published in:
- PLoS ONE, 2010, v. 5, n. 7, p. 1, doi. 10.1371/journal.pone.0011464
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- Publication type:
- Article
Parkinson Phenotype in Aged PINK1-Deficient Mice Is Accompanied by Progressive Mitochondrial Dysfunction in Absence of Neurodegeneration.
- Published in:
- PLoS ONE, 2009, v. 4, n. 6, p. 1, doi. 10.1371/journal.pone.0005777
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- Publication type:
- Article
Benefits of VCE-003.2, a cannabigerol quinone derivative, against inflammation-driven neuronal deterioration in experimental Parkinson's disease: possible involvement of different binding sites at the PPARγ receptor.
- Published in:
- 2018
- By:
- Publication type:
- journal article
VCE-003.2, a novel cannabigerol derivative, enhances neuronal progenitor cell survival and alleviates symptomatology in murine models of Huntington's disease.
- Published in:
- Scientific Reports, 2016, p. 29789, doi. 10.1038/srep29789
- By:
- Publication type:
- Article