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Activators of alpha synuclein expression identified by reporter cell line-based high throughput drug screen.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-98841-9
By:
- Stahl, Fabian;
- Denner, Philip;
- Piston, Dominik;
- Evert, Bernd O.;
- de Boni, Laura;
- Schmitt, Ina;
- Breuer, Peter;
- Wüllner, Ullrich
Publication type:
Article
Inhibition of Intercellular Cytosolic Traffic via Gap Junctions Reinforces Lomustine-Induced Toxicity in Glioblastoma Independent of MGMT Promoter Methylation Status.
Published in:
Pharmaceuticals (14248247), 2021, v. 14, n. 3, p. 195, doi. 10.3390/ph14030195
By:
- Schneider, Matthias;
- Potthoff, Anna-Laura;
- Evert, Bernd O.;
- Dicks, Marius;
- Ehrentraut, Denise;
- Dolf, Andreas;
- Schmidt, Elena N. C.;
- Schäfer, Niklas;
- Borger, Valeri;
- Pietsch, Torsten;
- Westhoff, Mike-Andrew;
- Güresir, Erdem;
- Waha, Andreas;
- Vatter, Hartmut;
- Heiland, Dieter H.;
- Schuss, Patrick;
- Herrlinger, Ulrich;
- Carvalho, Félix
Publication type:
Article
An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis.
Published in:
EMBO Journal, 2006, v. 25, n. 7, p. 1547, doi. 10.1038/sj.emboj.7601043
By:
- Boeddrich, Annett;
- Gaumer, Sébastien;
- Haacke, Annette;
- Tzvetkov, Nikolay;
- Albrecht, Mario;
- Evert, Bernd O.;
- Müller, Eva C.;
- Lurz, Rudi;
- Breuer, Peter;
- Schugardt, Nancy;
- Plaßmann, Stephanie;
- Kexiang Xu;
- Warrick, John M.;
- Suopanki, Jaana;
- Wüllner, Ullrich;
- Frank, Ronald;
- Hartl, Ulrich F.;
- Bonini, Nancy M.;
- Wanker, Erich E.
Publication type:
Article
Structural modeling of ataxin-3 reveals distant homology to adaptins.
Published in:
Proteins, 2003, v. 50, n. 2, p. 355, doi. 10.1002/prot.10280
By:
- Albrecht, Mario;
- Hoffmann, Daniel;
- Evert, Bernd O.;
- Schmitt, Ina;
- Wüllner, Ullrich;
- Lengauer, Thomas
Publication type:
Article
Inhibition of Gap Junctions Sensitizes Primary Glioblastoma Cells for Temozolomide.
Published in:
Cancers, 2019, v. 11, n. 6, p. 858, doi. 10.3390/cancers11060858
By:
- Potthoff, Anna-Laura;
- Heiland, Dieter Henrik;
- Evert, Bernd O.;
- Almeida, Filipe Rodrigues;
- Behringer, Simon P.;
- Dolf, Andreas;
- Güresir, Ági;
- Güresir, Erdem;
- Joseph, Kevin;
- Pietsch, Torsten;
- Schuss, Patrick;
- Herrlinger, Ulrich;
- Westhoff, Mike-Andrew;
- Vatter, Hartmut;
- Waha, Andreas;
- Schneider, Matthias
Publication type:
Article
Ataxin-3 Represses Transcription via Chromatin Binding, Interaction with Histone Deacetylase 3, and Histone Deacetylation.
Published in:
Journal of Neuroscience, 2006, v. 26, n. 44, p. 27, doi. 10.1523/JNEUROSCI.2053-06.2006
By:
- Evert, Bernd O.;
- Araujo, Julieta;
- Vieira-Saecker, Ana M.;
- De Vos, Rob A. I.;
- Harendza, Sigrid;
- Klockgether, Thomas;
- Wüllner, Ullrich
Publication type:
Article
Meclofenamate causes loss of cellular tethering and decoupling of functional networks in glioblastoma.
Published in:
Neuro-Oncology, 2021, v. 23, n. 11, p. 1885, doi. 10.1093/neuonc/noab092
By:
- Schneider, Matthias;
- Vollmer, Lea;
- Potthoff, Anna-Laura;
- Ravi, Vidhya M;
- Evert, Bernd O;
- Rahman, Mohummad A;
- Sarowar, Shahin;
- Kueckelhaus, Jan;
- Will, Paulina;
- Zurhorst, David;
- Joseph, Kevin;
- Maier, Julian P;
- Neidert, Nicolas;
- d'Errico, Paolo;
- Meyer-Luehmann, Melanie;
- Hofmann, Ulrich G;
- Dolf, Andreas;
- Salomoni, Paolo;
- Güresir, Erdem;
- Enger, Per Ø
Publication type:
Article
Mutant valosin‐containing protein causes a novel type of frontotemporal dementia.
Published in:
Annals of Neurology, 2005, v. 57, n. 3, p. 457
By:
- Rolf Schröder;
- Giles D. J. Watts;
- Sarju G. Mehta;
- Bernd O. Evert;
- Petra Broich;
- Klaus Fließbach;
- Katharina Pauls;
- Volkmar H. Hans;
- Virginia Kimonis;
- Dietmar R. Thal
Publication type:
Article
FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3.
Published in:
Human Molecular Genetics, 2011, v. 20, n. 15, p. 2928, doi. 10.1093/hmg/ddr197
By:
- Araujo, Julieta;
- Breuer, Peter;
- Dieringer, Susanne;
- Krauss, Sybille;
- Dorn, Stephanie;
- Zimmermann, Katrin;
- Pfeifer, Alexander;
- Klockgether, Thomas;
- Wuellner, Ullrich;
- Evert, Bernd O.
Publication type:
Article
Cell death in polyglutamine diseases.
Published in:
Cell & Tissue Research, 2000, v. 301, n. 1, p. 189, doi. 10.1007/s004410000228
By:
- Evert, Bernd O.;
- Wüllner, Ullrich;
- Klockgether, Thomas
Publication type:
Article
Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease.
Published in:
Nature, 2011, v. 480, n. 7378, p. 543, doi. 10.1038/nature10671
By:
- Koch, Philipp;
- Breuer, Peter;
- Peitz, Michael;
- Jungverdorben, Johannes;
- Kesavan, Jaideep;
- Poppe, Daniel;
- Doerr, Jonas;
- Ladewig, Julia;
- Mertens, Jerome;
- Tüting, Thomas;
- Hoffmann, Per;
- Klockgether, Thomas;
- Evert, Bernd O.;
- Wüllner, Ullrich;
- Brüstle, Oliver
Publication type:
Article
ATXN3 controls DNA replication and transcription by regulating chromatin structure.
Published in:
Nucleic Acids Research, 2023, v. 51, n. 11, p. 5396, doi. 10.1093/nar/gkad212
By:
- Hernández‐Carralero, Esperanza;
- Cabrera, Elisa;
- Rodríguez-Torres, Gara;
- Hernández-Reyes, Yeray;
- Singh, Abhay N;
- Santa-María, Cristina;
- Fernández-Justel, José Miguel;
- Janssens, Roel C;
- Marteijn, Jurgen A;
- Evert, Bernd O;
- Mailand, Niels;
- Gómez, María;
- Ramadan, Kristijan;
- Smits, Veronique A J;
- Freire, Raimundo
Publication type:
Article
CK2-dependent phosphorylation determines cellular localization and stability of ataxin-3.
Published in:
Human Molecular Genetics, 2009, v. 18, n. 17, p. 3334, doi. 10.1093/hmg/ddp274
By:
- Mueller, Thorsten;
- Breuer, Peter;
- Schmitt, Ina;
- Walter, Jochen;
- Evert, Bernd O.;
- Wüllner, Ullrich
Publication type:
Article
Rapamycin alleviates toxicity of different aggregate-prone proteins.
Published in:
Human Molecular Genetics, 2006, v. 15, n. 3, p. 433, doi. 10.1093/hmg/ddi458
By:
- Berger, Zdenek;
- Ravikumar, Brinda;
- Menzies, Fiona M.;
- Oroz, Lourdes Garcia;
- Underwood, Benjamin R.;
- Pangalos, Menelas N.;
- Schmitt, Ina;
- Wullner, Ullrich;
- Evert, Bernd O.;
- O'Kane, Cahir J.;
- Rubinsztein, David C.
Publication type:
Article
Upregulation of miR-370 and miR-543 is associated with reduced expression of heat shock protein 40 in spinocerebellar ataxia type 3.
Published in:
PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0201794
By:
- Evert, Bernd O.;
- Nalavade, Rohit;
- Jungverdorben, Johannes;
- Matthes, Frank;
- Weber, Stephanie;
- Rajput, Ashish;
- Bonn, Stefan;
- Brüstle, Oliver;
- Peitz, Michael;
- Krauß, Sybille
Publication type:
Article
Spinocerebellar Ataxia Type 3 Pathophysiology—Implications for Translational Research and Clinical Studies.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 7, p. 3984, doi. 10.3390/ijms25073984
By:
- Stahl, Fabian;
- Evert, Bernd O.;
- Han, Xinyu;
- Breuer, Peter;
- Wüllner, Ullrich
Publication type:
Article
The Alpha-Synuclein Gene (SNCA) is a Genomic Target of Methyl-CpG Binding Protein 2 (MeCP2)—Implications for Parkinson's Disease and Rett Syndrome.
Published in:
Molecular Neurobiology, 2024, v. 61, n. 10, p. 7830, doi. 10.1007/s12035-024-03974-3
By:
- Schmitt, Ina;
- Evert, Bernd O.;
- Sharma, Amit;
- Khazneh, Hassan;
- Murgatroyd, Chris;
- Wüllner, Ullrich
Publication type:
Article
High level expression of expanded full-length ataxin-3 in vitro causes cell death and formation of intranuclear inclusions in neuronal cells.
Published in:
Human Molecular Genetics, 1999, v. 8, n. 7, p. 1169, doi. 10.1093/hmg/8.7.1169
By:
- Evert, Bernd O.;
- Wullner, Ullrich;
- Schulz, Jorg B.;
- Weller, Michael;
- Groscurth, Peter;
- Trottier, Yvon;
- Brice, Alexis;
- Klockgether, Thomas
Publication type:
Article

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