Works by Evans, Emyr

Results: 17

Compromised astrocyte function and survival negatively impact neurons in infantile neuronal ceroid lipofuscinosis.

Published in:

Acta Neuropathologica Communications, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40478-018-0575-4

By:

Lange, Jenny;
Haslett, Luke J.;
Lloyd-Evans, Emyr;
Pocock, Jennifer M.;
Sands, Mark S.;
Williams, Brenda P.;
Cooper, Jonathan D.

Publication type:

Article

Lipids on Trial: The Search for the Offending Metabolite in Niemann-Pick type C Disease.

Published in:

Traffic, 2010, v. 11, n. 4, p. 419, doi. 10.1111/j.1600-0854.2010.01032.x

By:

Lloyd-Evans, Emyr;
Platt, Frances M.

Publication type:

Article

The Crystal Structure of Bacillus thuringiensis Tpp80Aa1 and Its Interaction with Galactose-Containing Glycolipids.

Published in:

Toxins, 2022, v. 14, n. 12, p. 863, doi. 10.3390/toxins14120863

By:

Best, Hannah L.;
Williamson, Lainey J.;
Lipka-Lloyd, Magdalena;
Waller-Evans, Helen;
Lloyd-Evans, Emyr;
Rizkallah, Pierre J.;
Berry, Colin

Publication type:

Article

PIP2 depletion and altered endocytosis caused by expression of Alzheimer's disease‐protective variant PLCγ2 R522.

Published in:

EMBO Journal, 2021, v. 40, n. 17, p. 1, doi. 10.15252/embj.2020105603

By:

Maguire, Emily;
Menzies, Georgina E;
Phillips, Thomas;
Sasner, Michael;
Williams, Harriet M;
Czubala, Magdalena A;
Evans, Neil;
Cope, Emma L;
Sims, Rebecca;
Howell, Gareth R;
Lloyd‐Evans, Emyr;
Williams, Julie;
Allen, Nicholas D;
Taylor, Philip R

Publication type:

Article

Regulation of TRPML1 function.

Published in:

Biochemical Society Transactions, 2015, v. 43, n. 3, p. 442, doi. 10.1042/BST20140311

By:

Waller-Evans, Helen;
Lloyd-Evans, Emyr

Publication type:

Article

Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium.

Published in:

Nature Medicine, 2008, v. 14, n. 11, p. 1247, doi. 10.1038/nm.1876

By:

Lloyd-Evans, Emyr;
Morgan, Anthony J.;
Xingxuan He;
Smith, David A.;
Elliot-Smith, Elena;
Sillence, Daniel J.;
Churchill, Grant C.;
Schuchman, Edward H.;
Galione, Antony;
Platt, Frances M.

Publication type:

Article

Ecological and Genetic Monitoring of a Recently Established Osprey (Pandion haliaetus) Population in Wales.

Published in:

Journal of Raptor Research, 2021, v. 55, n. 4, p. 635, doi. 10.3356/JRR-20-87

By:

Skujina, Ilze;
Ougham, Helen;
Evans, Emyr;
Monti, Flavio;
Kalvāns, Aigars;
Cross, Tony;
Macarie, Nicolae Adrian;
Hegarty, Matthew;
Shaw, Paul W.;
McKeown, Niall J.

Publication type:

Article

Niemann-Pick C-like Endolysosomal Dysfunction in DHDDS Patient Cells, a Congenital Disorder of Glycosylation, Can Be Treated with Miglustat.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1471, doi. 10.3390/ijms26041471

By:

Best, Hannah L.;
Cook, Sophie R.;
Waller-Evans, Helen;
Lloyd-Evans, Emyr

Publication type:

Article

On the move, lysosomal CAX drives Ca2+ transport and motility.

Published in:

Journal of Cell Biology, 2016, v. 212, n. 7, p. 755, doi. 10.1083/jcb.201603037

By:

Lloyd-Evans, Emyr

Publication type:

Article

Visualisation of cholesterol and ganglioside GM1 in zebrafish models of Niemann–Pick type C disease and Smith–Lemli–Opitz syndrome using light sheet microscopy.

Published in:

Histochemistry & Cell Biology, 2020, v. 154, n. 5, p. 565, doi. 10.1007/s00418-020-01925-2

By:

Cook, Sophie R.;
Bladen, Cerys;
Smith, Johanna;
Maguire, Emily;
Copner, Jordan;
Fenn, Gareth D.;
Wager, Kim;
Waller-Evans, Helen;
Lloyd-Evans, Emyr

Publication type:

Article

Investigating the Prevalence of Reactive Online Searching in the COVID-19 Pandemic: Infoveillance Study.

Published in:

2020

By:

Badell-Grau, Rafael A;
Cuff, Jordan Patrick;
Kelly, Brendan P;
Waller-Evans, Helen;
Lloyd-Evans, Emyr

Publication type:

journal article

Identification of dietary alanine toxicity and trafficking dysfunction in a Drosophila model of hereditary sensory and autonomic neuropathy type 1.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 24, p. 6899, doi. 10.1093/hmg/ddv390

By:

Oswald, Matthew C. W.;
West, Ryan J. H.;
Lloyd-Evans, Emyr;
Sweeney, Sean T.

Publication type:

Article

Biosynthesis and signalling functions of central and peripheral nervous system neurosteroids in health and disease.

Published in:

Essays in Biochemistry, 2020, v. 64, n. 3, p. 591, doi. 10.1042/EBC20200043

By:

Lloyd-Evans, Emyr;
Waller-Evans, Helen

Publication type:

Article

The Alzheimer's disease protective R522 variant of PLCg2, consistently enhances PLCγ2 activation, depleting PI(4,5)P<sub>2</sub> levels and altering cell function in in vitro and in vivo assays: Developing topics.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.047404

By:

Philips, Thomas Ernest James;
Maguire, Emily;
Menzies, Georgina E;
Sasner, Michael;
Williams, Harriet M;
Czubala, Magdalena;
Evans, Neil;
Cope, Emma L;
Sims, Rebecca;
Howell, Gareth;
Lloyd‐Evans, Emyr;
Williams, Julie;
Allen, Nicholas D;
Taylor, Philip

Publication type:

Article

TRPML1: A novel therapeutic target to remediate endolysosomal pathology in Alzheimer's disease: Human neuropathology: AD neuropathology.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043397

By:

Somogyi, Aleksandra;
Kirkham, Emily D.;
Lloyd‐Evans, Emyr;
Allen, Nicholas D.;
Anderson, Karen E.;
Hawkins, Phillip T.;
Sims, Rebecca;
Boland, Barry;
O'Neill, Cora

Publication type:

Article

O5‐10‐01: ENHANCED FUNCTION OF PLCG2 VARIANT P522R IN MACROPHAGES AND MICROGLIA IS ASSOCIATED WITH PROTECTION FROM ALZHEIMER'S DISEASE.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1641, doi. 10.1016/j.jalz.2019.06.4888

By:

Maguire, Emily;
Menzies, Georgina E.;
James Philips, Thomas Ernest;
Cope, Emma L.;
Czubala, Magdalena;
Evans, Neil;
Howell, Gareth;
Williams, Harriet M.;
Sasner, Michael;
Lloyd-Evans, Emyr;
Sims, Rebecca;
Williams, Julie;
Allen, Nicholas D.;
Taylor, Philip

Publication type:

Article

Beware of N -Benzoyloxybenzamides.

Published in:

Molecules, 2024, v. 29, n. 21, p. 5143, doi. 10.3390/molecules29215143

By:

Cubitt, Jonathan;
Davies, Mari;
Riseley, Ross;
Evans, Gabrielle;
Gardiner, Sian E.;
Kariuki, Benson M.;
Ward, Simon E.;
Lloyd-Evans, Emyr;
Waller-Evans, Helen;
Jones, D. Heulyn

Publication type:

Article