Works by Evan, Gerard

Results: 52

The last cut is the deepest.

Published in:

Nature, 1995, v. 376, n. 6535, p. 17, doi. 10.1038/376017a0

By:

Whyte, Moira;
Evan, Gerard

Publication type:

Article

Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis.

Published in:

Journal of Cell Biology, 2002, v. 157, n. 3, p. 429, doi. 10.1083/jcb.200201110

By:

Zongbing You;
Saims, Daniel;
Shaoqiong Chen;
Zhaocheng Zhang;
Guttridge, Denis C.;
Kun-liang Guan;
MacDougald, Ormond A.;
Brown, Anthony M.C.;
Evan, Gerard;
Kitajerski, Jan;
Cun-Yu Wang

Publication type:

Article

The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant.

Published in:

Nature Cell Biology, 2000, v. 2, n. 3, p. 156, doi. 10.1038/35004029

By:

Goldstein, Joshua C.;
Waterhouse, Nigel J.;
Juin, Phillipe;
Evan, Gerard I.;
Green, Douglas R.

Publication type:

Article

BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05790-5

By:

Lazarus, Kyren A.;
Hadi, Fazal;
Zambon, Elisabetta;
Bach, Karsten;
Santolla, Maria-Francesca;
Watson, Julie K.;
Correia, Lucia L.;
Das, Madhumita;
Ugur, Rosemary;
Pensa, Sara;
Becker, Lukas;
Campos, Lia S.;
Ladds, Graham;
Liu, Pentao;
Evan, Gerard I.;
McCaughan, Frank M.;
Le Quesne, John;
Lee, Joo-Hyeon;
Calado, Dinis;
Khaled, Walid T.

Publication type:

Article

SOX2 Drives Bronchial Dysplasia in a Novel Organotypic Model of Early Human Squamous Lung Cancer.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2017, v. 195, n. 11, p. 1494, doi. 10.1164/rccm.201510-2084OC

By:

Correia, Lúcia L.;
Johnson, Jo-Anne;
McErlean, Peter;
Bauer, Julien;
Farah, Hassan;
Rassl, Doris M.;
Rintoul, Robert C.;
Sethi, Tariq;
Lavender, Paul;
Rawlins, Emma L.;
Littlewood, Trevor D.;
Evan, Gerard I.;
McCaughan, Frank M.

Publication type:

Article

SOX2 Drives Bronchial Dysplasia in a Novel Organotypic Model of Early Human Squamous Lung Cancer.

Published in:

2017

By:

Correia, Lúcia L;
Johnson, Jo-Anne;
McErlean, Peter;
Bauer, Julien;
Farah, Hassan;
Rassl, Doris M;
Rintoul, Robert C;
Sethi, Tariq;
Lavender, Paul;
Rawlins, Emma L;
Littlewood, Trevor D;
Evan, Gerard I;
McCaughan, Frank M

Publication type:

journal article

In conversation with Gerard Evan.

Published in:

FEBS Journal, 2019, v. 286, n. 24, p. 4824, doi. 10.1111/febs.15121

By:

Dhillon, Paraminder;
Evan, Gerard

Publication type:

Article

Selective activation of p53-mediated tumour suppression in high-grade tumours.

Published in:

Nature, 2010, v. 468, n. 7323, p. 567, doi. 10.1038/nature09526

By:

Junttila, Melissa R.;
Karnezis, Anthony N.;
Garcia, Daniel;
Madriles, Francesc;
Kortlever, Roderik M.;
Rostker, Fanya;
Brown Swigart, Lamorna;
Pham, David M.;
Seo, Youngho;
Evan, Gerard I.;
Martins, Carla P.

Publication type:

Article

Modelling Myc inhibition as a cancer therapy.

Published in:

Nature, 2008, v. 455, n. 7213, p. 679, doi. 10.1038/nature07260

By:

Soucek, Laura;
Whitfield, Jonathan;
Martins, Carla P.;
Finch, Andrew J.;
Murphy, Daniel J.;
Sodir, Nicole M.;
Karnezis, Anthony N.;
Swigart, Lamorna Brown;
Nasi, Sergio;
Evan, Gerard I.

Publication type:

Article

Expression of Mad1 in T cells leads to reduced thymic cellularity and impaired mitogen-induced proliferation.

Published in:

Oncogene, 2001, v. 20, n. 10, p. 1164, doi. 10.1038/sj.onc.1204196

By:

Rudolph, Bettina;
Hueber, Anne-Odile;
Evan, Gerard I

Publication type:

Article

Reversible activation of c-Myc in thymocytes enhances positive selection and induces proliferation and apoptosis in vitro.

Published in:

Oncogene, 2000, v. 19, n. 15, p. 1891, doi. 10.1038/sj.onc.1203508

By:

Rudolph, Bettina;
Hueber, Anne-Odile;
Evan, Gerard I

Publication type:

Article

Sensitivity to myc-induced apoptosis is retained in spontaneous and transplanted lymphomas of CD2-mycER<sup>TM</sup> mice.

Published in:

Oncogene, 2000, v. 19, n. 6, p. 773, doi. 10.1038/sj.onc.1203321

By:

Blyth, Karen;
Stewart, Monica;
Bell, Margaret;
James, Clarwyn;
Evan, Gerard;
Neil, James C;
Cameron, Ewan R

Publication type:

Article

c-Myc and E1A induced cellular sensitivity to activated NK cells involves cytotoxic granules as death effectors.

Published in:

Oncogene, 1999, v. 18, n. 13, p. 2181, doi. 10.1038/sj.onc.1202546

By:

Klefstrom, Juha;
Kovanen, Panu E;
Somersalo, Kristina;
Hueber, Anne-Odile;
Littlewood, Trevor;
Evan, Gerard I;
Greenberg, Arnold H;
Saksela, Eero;
Timonen, Tuomo;
Alitalo, Kari

Publication type:

Article

The opposing roles of the Akt and c-Myc signalling pathways in survival from CD95-mediated apoptosis.

Published in:

Oncogene, 1998, v. 17, n. 22, p. 2811, doi. 10.1038/sj.onc.1202393

By:

Rohn, Jennifer L;
Hueber, Anne-Odile;
McCarthy, Nicola J;
Lyon, Debbie;
Navarro, Paloma;
Burgering, Boudewijn M Th;
Evan, Gerard I

Publication type:

Article

Temporal dissection of p53 function in vitro and in vivo.

Published in:

Nature Genetics, 2005, v. 37, n. 7, p. 718, doi. 10.1038/ng1572

By:

Christophorou, Maria A.;
Martin-Zanca, Dionisio;
Soucek, Laura;
Lawlor, Elizabeth R.;
Brown-Swigart, Lamorna;
Verschuren, Emmy W.;
Evan, Gerard I

Publication type:

Article

p53--a Jack of all trades but master of none.

Published in:

2009

By:

Junttila, Melissa R.;
Evan, Gerard I.

Publication type:

journal article

c-myc: more than just a matter of life and death.

Published in:

Nature Reviews Cancer, 2002, v. 2, n. 10, p. 764, doi. 10.1038/nrc904

By:

Pelengaris, Stella;
Khan, Mike;
Evan, Gerard

Publication type:

Article

MYC-Dependent Regulation and Prognostic Role of CIP2A in Gastric Cancer.

Published in:

JNCI: Journal of the National Cancer Institute, 2009, v. 101, n. 11, p. 793, doi. 10.1093/jnci/djp103

By:

Khanna, Anchit;
Böckelman, Camilla;
Hemmes, Annabrita;
Junttila, Melissa R.;
Wiksten, Jan-Patrik;
Lundin, Mikael;
Junnila, Siina;
Murphy, Daniel J.;
Evan, Gerard I.;
Haglund, Caj;
Westermarck, Jukka;
Ristimäki, Ari

Publication type:

Article

Caspase-8 in Apoptosis: The Beginning of "The End"?

Published in:

IUBMB Life, 2000, v. 50, n. 2, p. 85, doi. 10.1080/15216540050212088

By:

Kruidering, Marieke;
Evan, Gerard I.

Publication type:

Article

Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors.

Published in:

Nature Medicine, 2007, v. 13, n. 10, p. 1211, doi. 10.1038/nm1649

By:

Soucek, Laura;
Lawlor, Elizabeth R.;
Soto, Darya;
Shchors, Ksenya;
Swigart, Lamorna Brown;
Evan, Gerard I.

Publication type:

Article

Caspase 8: The killer you can't live without.

Published in:

Nature Medicine, 2000, v. 6, n. 5, p. 498, doi. 10.1038/74966

By:

Juin, Philippe;
Evan, Gerard

Publication type:

Article

p53 Restoration in Induction and Maintenance of Senescence: Differential Effects in Premalignant and Malignant Tumor Cells.

Published in:

Molecular & Cellular Biology, 2016, p. 438, doi. 10.1128/MCB.00747-15

By:

Harajly, Mohamad;
Zalzali, Hasan;
Ghayad, Sandra E.;
Ghamloush, Farah;
Basma, Hussein;
Rabeh, Wissam;
Badro, Danielle A.;
Saab, Raya;
Nawaz, Zafar;
Zainedin, Samiha;
Jabbour, Mark;
Tawil, Ayman;
Evan, Gerard I.

Publication type:

Article

Cancer therapy: Up close and personalized.

Published in:

2015

By:

Evan, Gerard

Publication type:

Book Review

A monoclonal anti-HLA antibody recognizes a mouse tumor-associated antigen.

Published in:

European Journal of Immunology, 1983, v. 13, n. 2, p. 160, doi. 10.1002/eji.1830130213

By:

Evan, Gerard I.;
Lennox, Edwin S.;
Alderson, Thomas;
Croft, Lorraine

Publication type:

Article

c-myc oncogene expression in colorectal cancer.

Published in:

1987

By:

Sikora, Karol;
Chan, Stephen;
Evan, Gerard;
Gabra, Hani;
Markham, Nicholas;
Stewart, Jonathan;
Watson, James;
Sikora, K;
Chan, S;
Evan, G;
Gabra, H;
Markham, N;
Stewart, J;
Watson, J

Publication type:

journal article

The Wnt signaling receptor Fzd9 is essential for Myc-driven tumorigenesis in pancreatic islets.

Published in:

Life Science Alliance, 2021, v. 4, n. 5, p. 1, doi. 10.26508/lsa.201900490

By:

Zacarías-Fluck, Mariano F.;
Jauset, Toni;
Martínez-Martín, Sandra;
Kaur, Jastrinjan;
Casacuberta-Serra, Sílvia;
Massó-Vallés, Daniel;
Serrano del Pozo, Erika;
Martín-Fernández, Génesis;
González-Larreategui, íñigo;
López-Estévez, Sergio;
Brown-Swigart, Lamorna;
Beaulieu, Marie-Eve;
Whitfield, Jonathan R.;
Madan, Babita;
Virshup, David M.;
Evan, Gerard I.;
Soucek, Laura

Publication type:

Article

Cancer-A matter of life and cell death.

Published in:

International Journal of Cancer, 1997, v. 71, n. 5, p. 709, doi. 10.1002/(SICI)1097-0215(19970529)71:5<709::AID-IJC2>3.0.CO;2-V

By:

Evan, Gerard

Publication type:

Article

The Drosophila caspase DRONC is regulated by DIAP1.

Published in:

EMBO Journal, 2000, v. 19, n. 4, p. 598, doi. 10.1093/emboj/19.4.598

By:

Meier, Pascal;
Silke, John;
Leevers, Sally J.;
Evan, Gerard I.

Publication type:

Article

Induction of TNF-sensitive cellular phenotype by c-Myc involves p53 and impaired NF-?B activation.

Published in:

EMBO Journal, 1997, v. 16, n. 24, p. 7382, doi. 10.1093/emboj/16.24.7382

By:

Klefstrom, Juha;
Arighi, Elena;
Littlewood, Trevor;
Jäättelä, Marja;
Saksela, Eero;
Evan, Gerard I.;
Alitalo, Kari

Publication type:

Article

drICE is an essential caspase required for apoptotic activity in Drosophila cells.

Published in:

EMBO Journal, 1997, v. 16, n. 20, p. 6192, doi. 10.1093/emboj/16.20.6192

By:

Fraser, Andrew G.;
McCarthy, Nicola J.;
Evan, Gerard I.

Publication type:

Article

Proliferation, cell cycle and apoptosis in cancer.

Published in:

Nature, 2001, v. 411, n. 6835, p. 342, doi. 10.1038/35077213

By:

Evan, Gerard I.;
Vousden, Karen H.

Publication type:

Article

Apoptosis in development.

Published in:

Nature, 2000, v. 407, n. 6805, p. 796, doi. 10.1038/35037734

By:

Meier, Pascal;
Finch, Andrew;
Evan, Gerard

Publication type:

Article

Specific TrkA survival signals interfere with different apoptotic pathways.

Published in:

Oncogene, 1998, v. 16, n. 7, p. 825, doi. 10.1038/sj.onc.1201842

By:

Ulrich, Eugen;
Duwel, Annette;
Kauffmann-Zeh, Andrea;
Gilbert, Chris;
Lyon, Debbie;
Rudkin, Brian;
Evan, Gerard;
Martin-Zanca, Dionisio

Publication type:

Article

Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis.

Published in:

Nature Communications, 2014, v. 5, n. 8, p. 4632, doi. 10.1038/ncomms5632

By:

Annibali, Daniela;
Whitfield, Jonathan R.;
Favuzzi, Emilia;
Jauset, Toni;
Serrano, Erika;
Cuartas, Isabel;
Redondo-Campos, Sara;
Folch, Gerard;
Gonzàlez-Juncà, Alba;
Sodir, Nicole M.;
Massó-Vallés, Daniel;
Beaulieu, Marie-Eve;
Swigart, Lamorna B.;
Mc Gee, Margaret M.;
Somma, Maria Patrizia;
Nasi, Sergio;
Seoane, Joan;
Evan, Gerard I.;
Soucek, Laura

Publication type:

Article

Intrinsic tumour suppression.

Published in:

Nature, 2004, v. 432, n. 7015, p. 307, doi. 10.1038/nature03098

By:

Lowe, Scott W.;
Cepero, Enrique;
Evan, Gerard

Publication type:

Article

Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15552-x

By:

Bywater, Megan J.;
Burkhart, Deborah L.;
Straube, Jasmin;
Sabò, Arianna;
Pendino, Vera;
Hudson, James E.;
Quaife-Ryan, Gregory A.;
Porrello, Enzo R.;
Rae, James;
Parton, Robert G.;
Kress, Theresia R.;
Amati, Bruno;
Littlewood, Trevor D.;
Evan, Gerard I.;
Wilson, Catherine H.

Publication type:

Article

Deficiency for the Cysteine Protease Cathepsin L Impairs Myc-Induced Tumorigenesis in a Mouse Model of Pancreatic Neuroendocrine Cancer.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0120348

By:

Brindle, Nicola R.;
Joyce, Johanna A.;
Rostker, Fanya;
Lawlor, Elizabeth R.;
Swigart-Brown, Lamorna;
Evan, Gerard;
Hanahan, Douglas;
Shchors, Ksenya

Publication type:

Article

Wild Type p53 Transcriptionally Represses the SALL2 Transcription Factor under Genotoxic Stress.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0073817

By:

Farkas, Carlos;
Martins, Carla P.;
Escobar, David;
Hepp, Matias I.;
Donner, David B.;
Castro, Ariel F.;
Evan, Gerard;
Gutiérrez, José L.;
Warren, Robert;
Pincheira, Roxana

Publication type:

Article

The Action Mechanism of the Myc Inhibitor Termed Omomyc May Give Clues on How to Target Myc for Cancer Therapy.

Published in:

PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022284

By:

Savino, Mauro;
Annibali, Daniela;
Carucci, Nicoletta;
Favuzzi, Emilia;
Cole, Michael D.;
Evan, Gerard I.;
Soucek, Laura;
Nasi, Sergio

Publication type:

Article

Defining the temporal requirements for Myc in the progression and maintenance of skin neoplasia.

Published in:

Oncogene, 2004, v. 23, n. 35, p. 5923, doi. 10.1038/sj.onc.1207796

By:

Flores, Ignacio;
Murphy, Daniel J.;
Swigart, Lamorna Brown;
Knies, Ulrike;
Evan, Gerard I.

Publication type:

Article

c-Myc recruits P-TEFb for transcription, cellular proliferation and apoptosis.

Published in:

Oncogene, 2003, v. 22, n. 36, p. 5707, doi. 10.1038/sj.onc.1206800

By:

Kanazawa, Satoshi;
Soucek, Laura;
Evan, Gerard;
Okamoto, Takashi;
Peterlin, B Matija

Publication type:

Article

Reversible Myc hypomorphism identifies a key Myc-dependency in early cancer evolution.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34079-x

By:

Sodir, Nicole M.;
Pellegrinet, Luca;
Kortlever, Roderik M.;
Campos, Tania;
Kwon, Yong-Won;
Kim, Shinseog;
Garcia, Daniel;
Perfetto, Alessandra;
Anastasiou, Panayiotis;
Swigart, Lamorna Brown;
Arends, Mark J.;
Littlewood, Trevor D.;
Evan, Gerard I.

Publication type:

Article

C-fos Induction in the Spinal Cord after Peripheral Nerve Lesion.

Published in:

European Journal of Neuroscience, 1991, v. 3, n. 9, p. 887, doi. 10.1111/j.1460-9568.1991.tb00100.x

By:

Williams, Simon;
Evan, Gerard;
Hunt, Stephen P.

Publication type:

Article

Acute Overexpression of Myc in Intestinal Epithelium Recapitulates Some but Not All the Changes Elicited by Wnt/β-Catenin Pathway Activation.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 19, p. 9, doi. 10.1128/MCB.01745-08

By:

Finch, Andrew J.;
Soucek, Laura;
Junttila, Melissa R.;
Swigart, Lamorna Brown;
Evan, Gerard I.

Publication type:

Article

Genetic Analysis of Myc and Telomerase Interactions In Vivo.

Published in:

Molecular & Cellular Biology, 2006, v. 26, n. 16, p. 18, doi. 10.1128/MCB.00543-06

By:

Flores, Ignacio;
Evan, Gerard;
Blasco, María A.

Publication type:

Article

1d2 Is Dispensable for Myc-Induced Epidermal Neoplasia.

Published in:

Molecular & Cellular Biology, 2004, v. 24, n. 5, p. 2083, doi. 10.1128/MCB.24.5.2083-2090.2004

By:

Murphy, Daniel J.;
Swigart, Lamorna Brown;
Israel, Mark A.;
Evan, Gerard I.

Publication type:

Article

Synthetic peptides in biochemical research.

Published in:

Molecular Biotechnology, 1995, v. 4, n. 1, p. 73, doi. 10.1007/BF02907472

By:

Hancock, David;
O'Reilly, Nicola;
Evan, Gerard

Publication type:

Article

KSHV viral cyclin interferes with T-cell development and induces lymphoma through Cdk6 and Notch activation in vivo.

Published in:

Cell Cycle, 2014, v. 13, n. 23, p. 3670, doi. 10.4161/15384101.2014.964118

By:

Pekkonen, Pirita;
Järviluoma, Annika;
Zinovkina, Nadezhda;
Cvrljevic, Anna;
Prakash, Sonam;
Westermarck, Jukka;
Evan, Gerard I;
Cesarman, Ethel;
Verschuren, Emmy W;
Ojala, Päivi M

Publication type:

Article

Regulated beta-cell regeneration in the adult mouse pancreas.

Published in:

2008

By:

Cano, David A;
Rulifson, Ingrid C;
Heiser, Patrick W;
Swigart, Lamorna B;
Pelengaris, Stella;
German, Mike;
Evan, Gerard I;
Bluestone, Jeffrey A;
Hebrok, Matthias

Publication type:

journal article

Regulated β-Cell Regeneration in the Adult Mouse Pancreas.

Published in:

Diabetes, 2008, v. 57, n. 4, p. 958, doi. 10.2337/db07-0913

By:

Cano, David A.;
Rulifson, Ingrid C.;
Heiser, Patrick W.;
Swigart, Lamorna B.;
Pelengaris, Stella;
German, Mike;
Evan, Gerard I.;
Bluestone, Jeffrey A.;
Hebrok, Matthias

Publication type:

Article