Works by Ettari, Roberta

Results: 43

Synthesis and Combination Studies of Novel Dipeptide Nitriles with Curcumin for a Potent Synergistic Action Against Rhodesain, Cysteine Protease of Trypanosoma brucei rhodesiense.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 847, doi. 10.3390/ph18060847

By:

Di Chio, Carla;
Starvaggi, Josè;
Previti, Santo;
De Luca, Fabiola;
Natale, Benito;
Cosconati, Sandro;
Schirmeister, Tanja;
Zappalà, Maria;
Ettari, Roberta

Publication type:

Article

Application of a Genus-Specific LAMP Assay for Schistosome Species to Detect Schistosoma haematobium x Schistosoma bovis Hybrids.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 6, p. 1308, doi. 10.3390/jcm10061308

By:

Crego-Vicente, Beatriz;
Fernández-Soto, Pedro;
Febrer-Sendra, Begoña;
García-Bernalt Diego, Juan;
Boissier, Jérôme;
Angora, Etienne K.;
Oleaga, Ana;
Muro, Antonio;
Ettari, Roberta

Publication type:

Article

BAY 11-7082 inhibits the NF-κB and NLRP3 inflammasome pathways and protects against IMQ-induced psoriasis.

Published in:

Clinical Science, 2017, v. 131, n. 6, p. 487, doi. 10.1042/CS20160645

By:

Irrera, Natasha;
Vaccaro, Mario;
Bitto, Alessandra;
Pallio, Giovanni;
Pizzino, Gabriele;
Lentini, Maria;
Arcoraci, Vincenzo;
Minutoli, Letteria;
Scuruchi, Michele;
Cutroneo, Giuseppina;
Pio Anastasi, Giuseppe;
Ettari, Roberta;
Squadrito, Francesco;
Altavilla, Domenica

Publication type:

Article

Evaluation of curcumin irreversibility.

Published in:

2020

By:

Ettari, Roberta;
Previti, Santo;
Maiorana, Santina;
Allegra, Alessandro;
Schirmeister, Tanja;
Grasso, Silvana;
Zappalà, Maria

Publication type:

Letter

Drug combination studies of curcumin and genistein against rhodesain of Trypanosoma brucei rhodesiense.

Published in:

Natural Product Research, 2019, v. 33, n. 24, p. 3577, doi. 10.1080/14786419.2018.1483927

By:

Ettari, Roberta;
Previti, Santo;
Maiorana, Santina;
Allegra, Alessandro;
Schirmeister, Tanja;
Grasso, Silvana;
Zappalà, Maria

Publication type:

Article

Potential Role of microRNAs in inducing Drug Resistance in Patients with Multiple Myeloma.

Published in:

Cells (2073-4409), 2021, v. 10, n. 2, p. 448, doi. 10.3390/cells10020448

By:

Allegra, Alessandro;
Ettari, Roberta;
Innao, Vanessa;
Bitto, Alessandra;
Kalyuzhny, Alexander E.

Publication type:

Article

Drug combination studies of PS-1 and quercetin against rhodesain of Trypanosoma brucei rhodesiense.

Published in:

Natural Product Research, 2022, v. 36, n. 16, p. 4282, doi. 10.1080/14786419.2021.1978993

By:

Di Chio, Carla;
Previti, Santo;
De Luca, Fabiola;
Allegra, Alessandro;
Zappalà, Maria;
Ettari, Roberta

Publication type:

Article

Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma MM.1R cells.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 1307, doi. 10.1080/14756366.2019.1594802

By:

Ettari, Roberta;
Pallio, Giovanni;
Pizzino, Gabriele;
Irrera, Natasha;
Zappalà, Maria;
Maiorana, Santina;
Di Chio, Carla;
Altavilla, Domenica;
Squadrito, Francesco;
Bitto, Alessandra

Publication type:

Article

Synthesis and biological evaluation of novel peptidomimetics as rhodesain inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1184, doi. 10.3109/14756366.2015.1108972

By:

Ettari, Roberta;
Previti, Santo;
Cosconati, Sandro;
Kesselring, Jochen;
Schirmeister, Tanja;
Grasso, Silvana;
Zappalà, Maria

Publication type:

Article

Drug Combination Studies of Isoquinolinone AM12 with Curcumin or Quercetin: A New Combination Strategy to Synergistically Inhibit 20S Proteasome.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 19, p. 10708, doi. 10.3390/ijms251910708

By:

Di Chio, Carla;
Previti, Santo;
Starvaggi, Josè;
De Luca, Fabiola;
Calabrò, Maria Luisa;
Zappalà, Maria;
Ettari, Roberta

Publication type:

Article

Development of Novel Peptidyl Nitriles Targeting Rhodesain and Falcipain-2 for the Treatment of Sleeping Sickness and Malaria.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 8, p. 4410, doi. 10.3390/ijms25084410

By:

Di Chio, Carla;
Starvaggi, Josè;
Totaro, Noemi;
Previti, Santo;
Natale, Benito;
Cosconati, Sandro;
Bogacz, Marta;
Schirmeister, Tanja;
Legac, Jenny;
Rosenthal, Philip J.;
Zappalà, Maria;
Ettari, Roberta

Publication type:

Article

The Inhibition of NS2B/NS3 Protease: A New Therapeutic Opportunity to Treat Dengue and Zika Virus Infection.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 8, p. 4376, doi. 10.3390/ijms25084376

By:

Starvaggi, Josè;
Previti, Santo;
Zappalà, Maria;
Ettari, Roberta

Publication type:

Article

Blunting Neuroinflammation by Targeting the Immunoproteasome with Novel Amide Derivatives.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 13, p. 10732, doi. 10.3390/ijms241310732

By:

Imbesi, Chiara;
Ettari, Roberta;
Irrera, Natasha;
Zappalà, Maria;
Pallio, Giovanni;
Bitto, Alessandra;
Mannino, Federica

Publication type:

Article

Virtual Screening Strategy and In Vitro Tests to Identify New Inhibitors of the Immunoproteasome.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 13, p. 10504, doi. 10.3390/ijms241310504

By:

Culletta, Giulia;
Tutone, Marco;
Ettari, Roberta;
Perricone, Ugo;
Di Chio, Carla;
Almerico, Anna Maria;
Zappalà, Maria

Publication type:

Article

Cysteine Proteases as Validated Targets for the Treatment of Neglected and Poverty-Related Parasitic Diseases.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 12, p. 10097, doi. 10.3390/ijms241210097

By:

Ettari, Roberta

Publication type:

Article

Dipeptide Nitrile CD34 with Curcumin: A New Improved Combination Strategy to Synergistically Inhibit Rhodesain of Trypanosoma brucei rhodesiense.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 10, p. 8477, doi. 10.3390/ijms24108477

By:

Di Chio, Carla;
Previti, Santo;
Totaro, Noemi;
De Luca, Fabiola;
Allegra, Alessandro;
Schirmeister, Tanja;
Zappalà, Maria;
Ettari, Roberta

Publication type:

Article

Monoclonal Antibodies: The Greatest Resource to Treat Multiple Myeloma.

Published in:

2023

By:

De Luca, Fabiola;
Allegra, Alessandro;
Di Chio, Carla;
Previti, Santo;
Zappalà, Maria;
Ettari, Roberta

Publication type:

Literature Review

Alarmins and MicroRNAs, a New Axis in the Genesis of Respiratory Diseases: Possible Therapeutic Implications.

Published in:

2023

By:

Allegra, Alessandro;
Murdaca, Giuseppe;
Gammeri, Luca;
Ettari, Roberta;
Gangemi, Sebastiano

Publication type:

Literature Review

The Impact of Curcumin on Immune Response: An Immunomodulatory Strategy to Treat Sepsis.

Published in:

2022

By:

Allegra, Alessandro;
Mirabile, Giuseppe;
Ettari, Roberta;
Pioggia, Giovanni;
Gangemi, Sebastiano

Publication type:

Literature Review

Drug Combination Studies of the Dipeptide Nitrile CD24 with Curcumin: A New Strategy to Synergistically Inhibit Rhodesain of Trypanosoma brucei rhodesiense.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 14470, doi. 10.3390/ijms232214470

By:

Di Chio, Carla;
Previti, Santo;
De Luca, Fabiola;
Bogacz, Marta;
Zimmer, Collin;
Wagner, Annika;
Schirmeister, Tanja;
Zappalà, Maria;
Ettari, Roberta

Publication type:

Article

A Proteomic Platform Unveils the Brain Glycogen Phosphorylase as a Potential Therapeutic Target for Glioblastoma Multiforme.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8200, doi. 10.3390/ijms23158200

By:

Ferraro, Giusy;
Mozzicafreddo, Matteo;
Ettari, Roberta;
Corsi, Lorenzo;
Monti, Maria Chiara

Publication type:

Article

Mechanism of falcipain-2 inhibition by α,β-unsaturated benzo[1,4]diazepin-2-one methyl ester.

Published in:

Journal of Computer-Aided Molecular Design, 2012, v. 26, n. 9, p. 1035, doi. 10.1007/s10822-012-9596-4

By:

Grazioso, Giovanni;
Legnani, Laura;
Toma, Lucio;
Ettari, Roberta;
Micale, Nicola;
Micheli, Carlo

Publication type:

Article

Synthesis and Cytotoxicity of Diarylpentanoids against Sensitive CCRF‐CEM and Multidrug‐Resistant CEM/ADR5000 Leukemia Cells.

Published in:

Chemistry & Biodiversity, 2022, v. 19, n. 2, p. 1, doi. 10.1002/cbdv.202100451

By:

Di Chio, Carla;
Zhou, Min;
Efferth, Thomas;
Schirmeister, Tanja;
Zappalà, Maria;
Ettari, Roberta

Publication type:

Article

Recent Advances in Nanotherapeutics for Multiple Myeloma.

Published in:

Cancers, 2020, v. 12, n. 11, p. 3144, doi. 10.3390/cancers12113144

By:

Iannazzo, Daniela;
Ettari, Roberta;
Giofrè, Salvatore;
Eid, Ali H.;
Bitto, Alessandra

Publication type:

Article

Efficient synthesis of kainic acid analogues.

Published in:

ARKIVOC: Online Journal of Organic Chemistry, 2013, p. 377

By:

Tamborini, Lucia;
Mastronardi, Federica;
Cullia, Gregorio;
Ettari, Roberta;
De Micheli, Carlo

Publication type:

Article

Synthesis and anti-HIV activity evaluation of new phenyl ethyl thiourea (PET) derivatives.

Published in:

ARKIVOC: Online Journal of Organic Chemistry, 2009, p. 227

By:

Ettari, Roberta;
Pinto, Andrea;
Micale, Nicola

Publication type:

Article

Development of Novel Benzodiazepine‐Based Peptidomimetics as Inhibitors of Rhodesain from Trypanosoma brucei rhodesiense.

Published in:

ChemMedChem, 2020, v. 15, n. 11, p. 995, doi. 10.1002/cmdc.202000158

By:

Di Chio, Carla;
Previti, Santo;
Amendola, Giorgio;
Cosconati, Sandro;
Schirmeister, Tanja;
Zappalà, Maria;
Ettari, Roberta

Publication type:

Article

Development of Novel Amides as Noncovalent Inhibitors of Immunoproteasomes.

Published in:

ChemMedChem, 2019, v. 14, n. 8, p. 842, doi. 10.1002/cmdc.201900028

By:

Ettari, Roberta;
Cerchia, Carmen;
Maiorana, Santina;
Guccione, Manuela;
Novellino, Ettore;
Bitto, Alessandra;
Grasso, Silvana;
Lavecchia, Antonio;
Zappalà, Maria

Publication type:

Article

Synthesis and Pharmacological Evaluation of α<sub>4</sub>β<sub>2</sub> Nicotinic Ligands with a 3-Fluoropyrrolidine Nucleus.

Published in:

ChemMedChem, 2015, v. 10, n. 6, p. 1071, doi. 10.1002/cmdc.201500073

By:

Tamborini, Lucia;
Pinto, Andrea;
Ettari, Roberta;
Gotti, Cecilia;
Fasoli, Francesca;
Conti, Paola;
De Micheli, Carlo

Publication type:

Article

Development of Novel Selective Peptidomimetics Containing a Boronic Acid Moiety, Targeting the 20S Proteasome as Anticancer Agents.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1801, doi. 10.1002/cmdc.201402075

By:

Scarbaci, Kety;
Troiano, Valeria;
Ettari, Roberta;
Pinto, Andrea;
Micale, Nicola;
Di Giovanni, Carmen;
Cerchia, Carmen;
Schirmeister, Tanja;
Novellino, Ettore;
Lavecchia, Antonio;
Zappalà, Maria;
Grasso, Silvana

Publication type:

Article

Synthesis and Biological Evaluation of Papain-Family Cathepsin L-Like Cysteine Protease Inhibitors Containing a 1,4-Benzodiazepine Scaffold as Antiprotozoal Agents.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1817, doi. 10.1002/cmdc.201402079

By:

Ettari, Roberta;
Pinto, Andrea;
Tamborini, Lucia;
Angelo, Ilenia C.;
Grasso, Silvana;
Zappalà, Maria;
Capodicasa, Natale;
Yzeiraj, Laura;
Gruber, Esther;
Aminake, Makoah N.;
Pradel, Gabriele;
Schirmeister, Tanja;
De Micheli, Carlo;
Conti, Paola

Publication type:

Article

Development of Rhodesain Inhibitors with a 3-Bromoisoxazoline Warhead.

Published in:

ChemMedChem, 2013, v. 8, n. 12, p. 2070, doi. 10.1002/cmdc.201300390

By:

Ettari, Roberta;
Tamborini, Lucia;
Angelo, Ilenia C.;
Grasso, Silvana;
Schirmeister, Tanja;
Lo Presti, Leonardo;
De Micheli, Carlo;
Pinto, Andrea;
Conti, Paola

Publication type:

Article

Synthesis and Molecular Modeling Studies of Derivatives of a Highly Potent Peptidomimetic Vinyl Ester as Falcipain-2 Inhibitors.

Published in:

ChemMedChem, 2012, v. 7, n. 9, p. 1594, doi. 10.1002/cmdc.201200274

By:

Ettari, Roberta;
Micale, Nicola;
Grazioso, Giovanni;
Bova, Floriana;
Schirmeister, Tanja;
Grasso, Silvana;
Zappalà, Maria

Publication type:

Article

Development of Novel Peptidomimetics Containing a Vinyl Sulfone Moiety as Proteasome Inhibitors.

Published in:

ChemMedChem, 2011, v. 6, n. 7, p. 1228, doi. 10.1002/cmdc.201100093

By:

Ettari, Roberta;
Bonaccorso, Cinzia;
Micale, Nicola;
Heindl, Cornelia;
Schirmeister, Tanja;
Calabrò, Maria Luisa;
Grasso, Silvana;
Zappalà, Maria

Publication type:

Article

Nonpeptidic Vinyl and Allyl Phosphonates as Falcipain-2 Inhibitors.

Published in:

ChemMedChem, 2008, v. 3, n. 7, p. 1030, doi. 10.1002/cmdc.200800050

By:

Ettari, Roberta;
Nizi, Emanuela;
Di Francesco, Maria Emilia;
Micale, Nicola;
Grasso, Silvana;
Zappalà, Maria;
Vičík, Radim;
Schirmeister, Tanja

Publication type:

Article

Peptide-Based Proteasome Inhibitors in Anticancer Drug Design.

Published in:

Medicinal Research Reviews, 2014, v. 34, n. 5, p. 1001, doi. 10.1002/med.21312

By:

Micale, Nicola;
Scarbaci, Kety;
Troiano, Valeria;
Ettari, Roberta;
Grasso, Silvana;
Zappalà, Maria

Publication type:

Article

Falcipain-2 inhibitors.

Published in:

Medicinal Research Reviews, 2010, v. 30, n. 1, p. 136, doi. 10.1002/med.20163

By:

Ettari, Roberta;
Bova, Floriana;
Zappalà, Maria;
Grasso, Silvana;
Micale, Nicola

Publication type:

Article

A Benzodiazepine-Derived Molecule That Interferes with the Bio-Mechanical Properties of Glioblastoma-Astrocytoma Cells Altering Their Proliferation and Migration.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 6, p. 2767, doi. 10.3390/ijms26062767

By:

Ragazzini, Gregorio;
Mescola, Andrea;
Tassinari, Riccardo;
Gallerani, Alessia;
Zannini, Chiara;
Di Rosa, Domenico;
Cavallini, Claudia;
Marcuzzi, Martina;
Taglioli, Valentina;
Bighi, Beatrice;
Ettari, Roberta;
Zappavigna, Vincenzo;
Ventura, Carlo;
Alessandrini, Andrea;
Corsi, Lorenzo

Publication type:

Article

Theranostic Applications of 2D Graphene-Based Materials for Solid Tumors Treatment.

Published in:

Nanomaterials (2079-4991), 2023, v. 13, n. 16, p. 2380, doi. 10.3390/nano13162380

By:

Iannazzo, Daniela;
Celesti, Consuelo;
Giofrè, Salvatore V.;
Ettari, Roberta;
Bitto, Alessandra

Publication type:

Article

Exploiting Curcumin Synergy With Natural Products Using Quantitative Analysis of Dose–Effect Relationships in an Experimental In Vitro Model of Osteoarthritis.

Published in:

Frontiers in Pharmacology, 2019, v. 10, p. 1, doi. 10.3389/fphar.2019.01347

By:

D'Ascola, Angela;
Irrera, Natasha;
Ettari, Roberta;
Bitto, Alessandra;
Pallio, Giovanni;
Mannino, Federica;
Atteritano, Marco;
Campo, Giuseppe M.;
Minutoli, Letteria;
Arcoraci, Vincenzo;
Squadrito, Violetta;
Picciolo, Giacomo;
Squadrito, Francesco;
Altavilla, Domenica

Publication type:

Article

Peptidyl Vinyl Ketone Irreversible Inhibitors of Rhodesain: Modifications of the P2 Fragment.

Published in:

ChemMedChem, 2020, v. 15, n. 16, p. 1552, doi. 10.1002/cmdc.202000360

By:

Maiorana, Santina;
Ettari, Roberta;
Previti, Santo;
Amendola, Giorgio;
Wagner, Annika;
Cosconati, Sandro;
Hellmich, Ute A.;
Schirmeister, Tanja;
Zappalà, Maria

Publication type:

Article

Development of Reduced Peptide Bond Pseudopeptide Michael Acceptors for the Treatment of Human African Trypanosomiasis.

Published in:

Molecules, 2022, v. 27, n. 12, p. 3765, doi. 10.3390/molecules27123765

By:

Previti, Santo;
Ettari, Roberta;
Di Chio, Carla;
Ravichandran, Rahul;
Bogacz, Marta;
Hellmich, Ute A.;
Schirmeister, Tanja;
Cosconati, Sandro;
Zappalà, Maria

Publication type:

Article

Immunoproteasome and Non-Covalent Inhibition: Exploration by Advanced Molecular Dynamics and Docking Methods.

Published in:

Molecules, 2021, v. 26, n. 13, p. 4046, doi. 10.3390/molecules26134046

By:

Culletta, Giulia;
Zappalà, Maria;
Ettari, Roberta;
Almerico, Anna Maria;
Tutone, Marco

Publication type:

Article