Works by Ervasti, James M.

Results: 41

Association of dystrophin-related protein with dystrophin-associated proteins in mdx mouse muscle.

Published in:

Nature, 1992, v. 360, n. 6404, p. 588, doi. 10.1038/360588a0

By:

Matsumura, Kiichiro;
Ervasti, James M.

Publication type:

Article

Functional Substitution by TAT-Utrophin in Dystrophin-Deficient Mice.

Published in:

PLoS Medicine, 2009, v. 6, n. 5, p. 1, doi. 10.1371/journal.pmed.1000083

By:

Sonnemann, Kevin J.;
Heun-Johnson, Hanke;
Turner, Amy J.;
Baltgalvis, Kristen A.;
Lowe, Dawn A.;
Ervasti, James M.

Publication type:

Article

The utrophin actin-binding domain binds F-actin in two different modes: implications for the spectrin superfamily of proteins.

Published in:

Journal of Cell Biology, 2002, v. 157, n. 2, p. 243, doi. 10.1083/jcb.200111097

By:

Galkin, Vitold E.;
Orlova, Albina;
VanLoock, Margaret S.;
Rybakova, Inna N.;
Ervasti, James M.;
Egelman, Edward H.

Publication type:

Article

In vitro stability of therapeutically relevant, internally truncated dystrophins.

Published in:

Skeletal Muscle, 2015, v. 5, n. 1, p. 1, doi. 10.1186/s13395-015-0040-z

By:

McCourt, Jackie L.;
Rhett, Katrina K.;
Jaeger, Michele A.;
Belanto, Joseph J.;
Talsness, Dana M.;
Ervasti, James M.

Publication type:

Article

Context-dependent functional substitution of α-skeletal actin by γ-cytoplasmic actin.

Published in:

FASEB Journal, 2009, v. 23, n. 7, p. 2205, doi. 10.1096/fj.09-129783

By:

Jaeger, Michele A.;
Sonnemann, Kevin J.;
Fitzsimons, Daniel P.;
Prins, Kurt W.;
Ervasti, James M.

Publication type:

Article

Variable cytoplasmic actin expression impacts the sensitivity of different dystrophin‐deficient mdx skeletal muscles to eccentric contraction.

Published in:

FEBS Journal, 2019, v. 286, n. 13, p. 2562, doi. 10.1111/febs.14831

By:

Lindsay, Angus;
Southern, William M.;
McCourt, Preston M.;
Larson, Alexie A.;
Hodges, James S.;
Lowe, Dawn A.;
Ervasti, James M.

Publication type:

Article

Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms.

Published in:

FEBS Journal, 2018, v. 285, n. 3, p. 481, doi. 10.1111/febs.14367

By:

O'Rourke, Allison R.;
Lindsay, Angus;
Tarpey, Michael D.;
Yuen, Samantha;
McCourt, Preston;
Nelson, D'anna M.;
Perrin, Benjamin J.;
Thomas, David D.;
Spangenburg, Espen E.;
Lowe, Dawn A.;
Ervasti, James M.

Publication type:

Article

Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia.

Published in:

Nature, 2012, v. 481, n. 7382, p. 520, doi. 10.1038/nature10745

By:

Zhang, Duan-Sun;
Piazza, Valeria;
Perrin, Benjamin J.;
Rzadzinska, Agnieszka K.;
Poczatek, J. Collin;
Wang, Mei;
Prosser, Haydn M.;
Ervasti, James M.;
Corey, David P.;
Lechene, Claude P.

Publication type:

Article

Retention of stress susceptibility in the mdx mouse model of Duchenne muscular dystrophy after PGC-1α overexpression or ablation of IDO1 or CD38.

Published in:

Human Molecular Genetics, 2024, v. 33, n. 7, p. 594, doi. 10.1093/hmg/ddad206

By:

Johnson, Erynn E;
Southern, W Michael;
Doud, Baird;
Steiger, Brandon;
Razzoli, Maria;
Bartolomucci, Alessandro;
Ervasti, James M

Publication type:

Article

Corrigendum: Persistent upregulation of the β-tubulin tubb6, linked to muscle regeneration, is a source of microtubule disorganization in dystrophic muscle.

Published in:

Human Molecular Genetics, 2019, v. 28, n. 11, p. 1930, doi. 10.1093/hmg/ddz035

By:

Randazzo, Davide;
Khalique, Umara;
Belanto, Joseph J;
Kenea, Aster;
Talsness, Dana M;
Olthoff, John T;
Tran, Michelle D;
Zaal, Kristien J;
Pak, Katherine;
Pinal-Fernandez, Iago;
Mammen, Andrew L;
Sackett, Dan;
Ervasti, James M;
Ralston, Evelyn

Publication type:

Article

Persistent upregulation of the β-tubulin tubb6, linked to muscle regeneration, is a source of microtubule disorganization in dystrophic muscle.

Published in:

Human Molecular Genetics, 2019, v. 28, n. 7, p. 1117, doi. 10.1093/hmg/ddy418

By:

Randazzo, Davide;
Khalique, Umara;
Belanto, Joseph J;
Kenea, Aster;
Talsness, Dana M;
Olthoff, John T;
Tran, Michelle D;
Zaal, Kristien J;
Pak, Katherine;
Pinal-Fernandez, Iago;
Mammen, Andrew L;
Sackett, Dan;
Ervasti, James M;
Ralston, Evelyn

Publication type:

Article

Dystrophinopathy-associated dysfunction of Krebs cycle metabolism.

Published in:

Human Molecular Genetics, 2019, v. 28, n. 6, p. 942, doi. 10.1093/hmg/ddy404

By:

Lindsay, Angus;
Chamberlain, Christopher M;
Witthuhn, Bruce A;
Lowe, Dawn A;
Ervasti, James M

Publication type:

Article

Variable rescue of microtubule and physiological phenotypes in mdx muscle expressing different miniaturized dystrophins.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 15, p. 2773, doi. 10.1093/hmg/ddy209

By:

Nelson, D’anna M;
Lindsay, Angus;
Judge, Luke M;
Duan, Dongsheng;
Chamberlain, Jeffrey S;
Lowe, Dawn A;
Ervasti, James M

Publication type:

Article

Variable rescue of microtubule and physiological phenotypes in mdx muscle expressing different miniaturized dystrophins.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 12, p. 2090, doi. 10.1093/hmg/ddy113

By:

Nelson, D'anna M.;
Lindsay, Angus;
Judge, Luke M.;
Duan, Dongsheng;
Chamberlain, Jeffrey S.;
Lowe, Dawn A.;
Ervasti, James M.

Publication type:

Article

Mouse models of two missense mutations in actin-binding domain 1 of dystrophin associated with Duchenne or Becker muscular dystrophy.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 3, p. 451, doi. 10.1093/hmg/ddx414

By:

McCourt, Jackie L.;
Talsness, Dana M.;
Lindsay, Angus;
Arpke, Robert W.;
Chatterton, Paul D.;
Nelson, D'anna M.;
Chamberlain, Christopher M.;
Olthoff, John T.;
Belanto, Joseph J.;
McCourt, Preston M.;
Kyba, Michael;
Lowe, Dawn A.;
Ervasti, James M.

Publication type:

Article

High Frequency Hearing Loss and Hyperactivity in DUX4 Transgenic Mice.

Published in:

PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0151467

By:

Dandapat, Abhijit;
Perrin, Benjamin J.;
Cabelka, Christine;
Razzoli, Maria;
Ervasti, James M.;
Bartolomucci, Alessandro;
Lowe, Dawn A.;
Kyba, Michael

Publication type:

Article

Tetrahydrobiopterin synthesis and metabolism is impaired in dystrophin‐deficient mdx mice and humans.

Published in:

Acta Physiologica, 2021, v. 231, n. 4, p. 1, doi. 10.1111/apha.13627

By:

Lindsay, Angus;
Kemp, Bailey;
Larson, Alexie A.;
Baumann, Cory W.;
McCourt, Preston M.;
Holm, John;
Karachunski, Peter;
Lowe, Dawn A.;
Ervasti, James M.

Publication type:

Article

β-Actin and Fascin-2 Cooperate to Maintain Stereocilia Length.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 19, p. 8114, doi. 10.1523/JNEUROSCI.0238-13.2013

By:

Perrin, Benjamin J.;
Strandjord, Dana M.;
Narayanan, Praveena;
Henderson, Davin M.;
Johnson, Kenneth R.;
Ervasti, James M.

Publication type:

Article

Loss of peroxiredoxin-2 exacerbates eccentric contraction-induced force loss in dystrophin-deficient muscle.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07639-3

By:

Olthoff, John T.;
Lindsay, Angus;
Abo-Zahrah, Reem;
Baltgalvis, Kristen A.;
Patrinostro, Xiaobai;
Belanto, Joseph J.;
Yu, Dae-Yeul;
Perrin, Benjamin J.;
Garry, Daniel J.;
Rodney, George G.;
Lowe, Dawn A.;
Ervasti, James M.

Publication type:

Article

Distinct mechanical properties in homologous spectrin-like repeats of utrophin.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-41569-4

By:

Rajaganapathy, Sivaraman;
McCourt, Jackie L.;
Ghosal, Sayan;
Lindsay, Angus;
McCourt, Preston M.;
Lowe, Dawn A.;
Ervasti, James M.;
Salapaka, Murti V.

Publication type:

Article

Do actin isoforms have unique functionalities at the protein level?

Published in:

Nature Communications, 2025, v. 16, p. 1, doi. 10.1038/s41467-025-57103-2

By:

Ervasti, James M.;
Kashina, Anna S.;
Perrin, Benjamin J.

Publication type:

Article

Contraction-Induced Loss of Plasmalemmal Electrophysiological Function Is Dependent on the Dystrophin Glycoprotein Complex.

Published in:

Frontiers in Physiology, 2021, v. 12, p. 1, doi. 10.3389/fphys.2021.757121

By:

Baumann, Cory W.;
Lindsay, Angus;
Sidky, Sylvia R.;
Ervasti, James M.;
Warren, Gordon L.;
Lowe, Dawn A.

Publication type:

Article

Mechanical factors tune the sensitivity of mdx muscle to eccentric strength loss and its protection by antioxidant and calcium modulators.

Published in:

Skeletal Muscle, 2020, v. 10, n. 1, p. 1, doi. 10.1186/s13395-020-0221-2

By:

Lindsay, Angus;
Baumann, Cory W.;
Rebbeck, Robyn T.;
Yuen, Samantha L.;
Southern, William M.;
Hodges, James S.;
Cornea, Razvan L.;
Thomas, David D.;
Ervasti, James M.;
Lowe, Dawn A.

Publication type:

Article

Pax3-induced expansion enables the genetic correction of dystrophic satellite cells.

Published in:

Skeletal Muscle, 2015, v. 5, p. 1, doi. 10.1186/s13395-015-0061-7

By:

Filareto, Antonio;
Rinaldi, Fabrizio;
Arpke, Robert W.;
Darabi, Radbod;
Belanto, Joseph J.;
Toso, Erik A.;
Miller, Auston Z.;
Ervasti, James M.;
McIvor, R. Scott;
Kyba, Michael;
Perlingeiro, Rita C. R.

Publication type:

Article

Dystrophin is a microtubule-associated protein.

Published in:

Journal of Cell Biology, 2009, v. 186, n. 3, p. 363, doi. 10.1083/jcb.200905048

By:

Prins, Kurt W.;
Humston, Jill L.;
Mehta, Amisha;
Tate, Victoria;
Ralston, Evelyn;
Ervasti, James M.

Publication type:

Article

Length regulation of mechanosensitive stereocilia depends on very slow actin dynamics and filament-severing proteins.

Published in:

Nature Communications, 2015, v. 6, n. 4, p. 6855, doi. 10.1038/ncomms7855

By:

Narayanan, Praveena;
Chatterton, Paul;
Ikeda, Akihiro;
Ikeda, Sakae;
Corey, David P.;
Ervasti, James M.;
Perrin, Benjamin J.

Publication type:

Article

An ex vivo gene therapy approach to treat muscular dystrophy using inducible pluripotent stem cells.

Published in:

Nature Communications, 2013, v. 4, n. 3, p. 1549, doi. 10.1038/ncomms2550

By:

Filareto, Antonio;
Parker, Sarah;
Darabi, Radbod;
Borges, Luciene;
Iacovino, Michelina;
Schaaf, Tory;
Mayerhofer, Timothy;
Chamberlain, Jeffrey S.;
Ervasti, James M.;
McIvor, R. Scott;
Kyba, Michael;
Perlingeiro, Rita C. R.

Publication type:

Article

Human dystrophin tandem calponin homology actin‐binding domain crystallized in a closed‐state conformation.

Published in:

Acta Crystallographica: Section D, Structural Biology, 2025, v. 81, n. 3, p. 122, doi. 10.1107/S2059798325001457

By:

Streeter, Oakley;
Shi, Ke;
Vavra, Joseph;
Aihara, Hideki;
Ervasti, James M.;
Evans, Robert;
Muretta, Joseph M.

Publication type:

Article

Neopterin/7,8‐dihydroneopterin is elevated in Duchenne muscular dystrophy patients and protects mdx skeletal muscle function.

Published in:

Experimental Physiology, 2018, v. 103, n. 7, p. 995, doi. 10.1113/EP087031

By:

Lindsay, Angus;
Schmiechen, Alexandra;
Chamberlain, Christopher M.;
Ervasti, James M.;
Lowe, Dawn A.

Publication type:

Article

Independent variability of microtubule perturbations associated with dystrophinopathy.

Published in:

Human Molecular Genetics, 2016, v. 25, n. 22, p. 4951, doi. 10.1093/hmg/ddw318

By:

Belanto, Joseph J.;
Olthoff, John T.;
Mader, Tara L.;
Chamberlain, Christopher M.;
Nelson, D'anna M.;
McCourt, Preston M.;
Talsness, Dana M.;
Gundersen, Gregg G.;
Lowe, Dawn A.;
Ervasti, James M.

Publication type:

Article

Internal deletion compromises the stability of dystrophin.

Published in:

Human Molecular Genetics, 2011, v. 20, n. 15, p. 2955, doi. 10.1093/hmg/ddr199

By:

Henderson, Davin M.;
Belanto, Joseph J.;
Li, Bin;
Heun-Johnson, Hanke;
Ervasti, James M.

Publication type:

Article

Dystrophin Deficiency Compromises Force Production of the Extensor Carpi Ulnaris Muscle in the Canine Model of Duchenne Muscular Dystrophy.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044438

By:

Yang, Hsiao T.;
Jin-Hong Shin;
Hakim, Chady H.;
Xiufang Pan;
Terjung, Ronald L.;
Duan, Dongsheng;
Ervasti, James M.

Publication type:

Article

Restricted Morphological and Behavioral Abnormalities following Ablation of β-Actin in the Brain.

Published in:

PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032970

By:

Cheever, Thomas R.;
Bin Li;
Ervasti, James M.

Publication type:

Article

Axonal Regeneration and Neuronal Function Are Preserved in Motor Neurons Lacking ßActin In Vivo.

Published in:

PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0017768

By:

Cheever, Thomas R.;
Olson, Emily A.;
Ervasti, James M.

Publication type:

Article

Destabilization of the Dystrophin-Glycoprotein Complex without Functional Deficits in α-Dystrobrevin Null Muscle.

Published in:

PLoS ONE, 2008, v. 3, n. 7, p. 1, doi. 10.1371/journal.pone.0002604

By:

Bunnell, Tina M.;
Jaeger, Michele A.;
Fitzsimons, Daniel P.;
Prins, Kurt W.;
Ervasti, James M.

Publication type:

Article

Skeletal Muscle-Specific Ablation of γ<sub>cyto</sub>-Actin Does Not Exacerbate the mdx Phenotype.

Published in:

PLoS ONE, 2008, v. 3, n. 6, p. 1, doi. 10.1371/journal.pone.0002419

By:

Prins, Kurt W.;
Lowe, Dawn A.;
Ervasti, James M.

Publication type:

Article

Expression of Dp260 in muscle tethers the actin cytoskeleton to the dystrophin–glycoprotein complex and partially prevents dystrophy.

Published in:

Human Molecular Genetics, 2002, v. 11, n. 9, p. 1095, doi. 10.1093/hmg/11.9.1095

By:

Warner, Laura E.;
DelloRusso, Christiana;
Crawford, Robert W.;
Rybakova, Inna N.;
Patel, Jitandrakumar R.;
Ervasti, James M.;
Chamberlain, Jeffrey S.

Publication type:

Article

The actin gene family: Function follows isoform.

Published in:

Cytoskeleton, 2010, v. 67, n. 10, p. 630, doi. 10.1002/cm.20475

By:

Perrin, Benjamin J.;
Ervasti, James M.

Publication type:

Article

Delayed embryonic development and impaired cell growth and survival in Actg1 null mice.

Published in:

Cytoskeleton, 2010, v. 67, n. 9, p. 564, doi. 10.1002/cm.20467

By:

Bunnell, Tina M.;
Ervasti, James M.

Publication type:

Article

Brain α-dystroglycan displays unique glycoepitopes and preferential binding to laminin-10/11

Published in:

FEBS Letters, 2006, v. 580, n. 14, p. 3381, doi. 10.1016/j.febslet.2006.05.010

By:

McDearmon, Erin L.;
Combs, Ariana C.;
Sekiguchi, Kiyotoshi;
Fujiwara, Hironobu;
Ervasti, James M.

Publication type:

Article

Some dystrophy phenotypes of dystrophin-deficient mdx mice are exacerbated by mild, repetitive daily stress.

Published in:

FASEB Journal, 2021, v. 35, n. 4, p. 1, doi. 10.1096/fj.202002500R

By:

Lindsay, Angus;
Holm, John;
Razzoli, Maria;
Bartolomucci, Alessandro;
Ervasti, James M.;
Lowe, Dawn A.

Publication type:

Article