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Anti-seizure effects of JNJ-54175446 in the intra-amygdala kainic acid model of drug-resistant temporal lobe epilepsy in mice.
- Published in:
- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2023.1308478
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- Publication type:
- Article
Immunoproteasome deficiency results in age-dependent development of epilepsy.
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- Brain Communications, 2024, v. 6, n. 1, p. 1, doi. 10.1093/braincomms/fcae017
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- Publication type:
- Article
The P2X7 receptor contributes to seizures and inflammation‐driven long‐lasting brain hyperexcitability following hypoxia in neonatal mice.
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- British Journal of Pharmacology, 2023, v. 180, n. 13, p. 1710, doi. 10.1111/bph.16033
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- Article
P2X7 receptor inhibition ameliorates ubiquitin–proteasome system dysfunction associated with Alzheimer's disease.
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- Alzheimer's Research & Therapy, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13195-023-01258-x
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- Article
The P2X7 Receptor as a Mechanistic Biomarker for Epilepsy.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5410, doi. 10.3390/ijms24065410
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- Article
Increased uptake of the P2X7 receptor radiotracer <sup>18</sup>F‐JNJ‐64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice.
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- Epilepsia (Series 4), 2023, v. 64, n. 2, p. 511, doi. 10.1111/epi.17484
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- Publication type:
- Article
Highly efficient fermentation of 5-keto-d-fructose with Gluconobacter oxydans at different scales.
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- Microbial Cell Factories, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12934-022-01980-5
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- Publication type:
- Article
Purinergic Signalling and Inflammation-Related Diseases.
- Published in:
- Cells (2073-4409), 2022, v. 11, n. 23, p. 3748, doi. 10.3390/cells11233748
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- Article
Editorial: The molecular mechanisms of epilepsy and potential therapeutics.
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- Frontiers in Molecular Neuroscience, 2022, v. 15, p. 1, doi. 10.3389/fnmol.2022.1064121
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- Publication type:
- Article
Increased expression of the ATP‐gated P2X7 receptor reduces responsiveness to anti‐convulsants during status epilepticus in mice.
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- British Journal of Pharmacology, 2022, v. 179, n. 12, p. 2986, doi. 10.1111/bph.15785
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- Publication type:
- Article
Beyond Seizure Control: Treating Comorbidities in Epilepsy via Targeting of the P2X7 Receptor.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 4, p. 2380, doi. 10.3390/ijms23042380
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- Article
Inherent P2X7 Receptors Regulate Macrophage Functions during Inflammatory Diseases.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 232, doi. 10.3390/ijms23010232
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- Publication type:
- Article
Novel Point-of-Care Diagnostic Method for Neonatal Encephalopathy Using Purine Nucleosides.
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- Frontiers in Molecular Neuroscience, 2021, v. 14, p. 1, doi. 10.3389/fnmol.2021.732199
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- Publication type:
- Article
Circulating P2X7 Receptor Signaling Components as Diagnostic Biomarkers for Temporal Lobe Epilepsy.
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- Cells (2073-4409), 2021, v. 10, n. 9, p. 2444, doi. 10.3390/cells10092444
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- Publication type:
- Article
Progressive Mitochondrial SOD1 G93A Accumulation Causes Severe Structural, Metabolic and Functional Aberrations through OPA1 Down-Regulation in a Mouse Model of Amyotrophic Lateral Sclerosis.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 15, p. 8194, doi. 10.3390/ijms22158194
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- Publication type:
- Article
Targeting Neuroinflammation via Purinergic P2 Receptors for Disease Modification in Drug-Refractory Epilepsy.
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- Journal of Inflammation Research, 2021, v. 14, p. 3367, doi. 10.2147/JIR.S287740
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- Article
Editorial: P2X7 as Common Therapeutic Target in Brain Diseases.
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- 2021
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- Publication type:
- Editorial
Elevated blood purine levels as a biomarker of seizures and epilepsy.
- Published in:
- Epilepsia (Series 4), 2021, v. 62, n. 3, p. 817, doi. 10.1111/epi.16839
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- Publication type:
- Article
High concordance between hippocampal transcriptome of the mouse intra‐amygdala kainic acid model and human temporal lobe epilepsy.
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- Epilepsia (Series 4), 2020, v. 61, n. 12, p. 2795, doi. 10.1111/epi.16714
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- Publication type:
- Article
The Medical Triazole Voriconazole Can Select for Tandem Repeat Variations in Azole-Resistant Aspergillus Fumigatus Harboring TR<sub>34</sub>/L98H via Asexual Reproduction.
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- Journal of Fungi, 2020, v. 6, n. 4, p. 1, doi. 10.3390/jof6040277
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- Article
Deviant reporter expression and P2X4 passenger gene overexpression in the soluble EGFP BAC transgenic P2X7 reporter mouse model.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-76428-0
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- Publication type:
- Article
Neonatal Seizures and Purinergic Signalling.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 21, p. 7832, doi. 10.3390/ijms21217832
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- Publication type:
- Article
Characterization of the Expression of the ATP-Gated P2X7 Receptor Following Status Epilepticus and during Epilepsy Using a P2X7-EGFP Reporter Mouse.
- Published in:
- Neuroscience Bulletin, 2020, v. 36, n. 11, p. 1242, doi. 10.1007/s12264-020-00573-9
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- Publication type:
- Article
Genetic deletion of microRNA-22 blunts the inflammatory transcriptional response to status epilepticus and exacerbates epilepsy in mice.
- Published in:
- Molecular Brain, 2020, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13041-020-00653-x
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- Publication type:
- Article
P2X7 Receptor-Dependent microRNA Expression Profile in the Brain Following Status Epilepticus in Mice.
- Published in:
- Frontiers in Molecular Neuroscience, 2020, v. 13, p. N.PAG, doi. 10.3389/fnmol.2020.00127
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- Publication type:
- Article
Polyadenylation of mRNA as a novel regulatory mechanism of gene expression in temporal lobe epilepsy.
- Published in:
- 2020
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- Publication type:
- journal article
Evaluation of a New Culture Protocol for Enhancing Fungal Detection Rates in Respiratory Samples of Cystic Fibrosis Patients.
- Published in:
- Journal of Fungi, 2020, v. 6, n. 2, p. 1, doi. 10.3390/jof6020082
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- Publication type:
- Article
Differential Expression of the Metabotropic P2Y Receptor Family in the Cortex Following Status Epilepticus and Neuroprotection via P2Y<sub>1</sub> Antagonism in Mice.
- Published in:
- Frontiers in Pharmacology, 2020, v. 10, p. 1, doi. 10.3389/fphar.2019.01558
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- Publication type:
- Article
Tau Phosphorylation in a Mouse Model of Temporal Lobe Epilepsy.
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- Frontiers in Aging Neuroscience, 2019, v. 11, p. 1, doi. 10.3389/fnagi.2019.00308
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- Publication type:
- Article
Elevated Plasma microRNA-206 Levels Predict Cognitive Decline and Progression to Dementia from Mild Cognitive Impairment.
- Published in:
- Biomolecules (2218-273X), 2019, v. 9, n. 11, p. 734, doi. 10.3390/biom9110734
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- Article
Proteins and microRNAs are differentially expressed in tear fluid from patients with Alzheimer's disease.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-51837-y
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- Publication type:
- Article
Context-Specific Switch from Anti- to Pro-epileptogenic Function of the P2Y<sub>l</sub> Receptor in Experimental Epilepsy.
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- Journal of Neuroscience, 2019, v. 39, n. 27, p. 5377, doi. 10.1523/jneurosci.0089-19.2019
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- Publication type:
- Article
Antagonizing Increased miR-135a Levels at the Chronic Stage of Experimental TLE Reduces Spontaneous Recurrent Seizures.
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- Journal of Neuroscience, 2019, v. 39, n. 26, p. 5064, doi. 10.1523/JNEUROSCI.3014-18.2019
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- Article
Aerosol Transmission of Aspergillus fumigatus in Cystic Fibrosis Patients in the Netherlands.
- Published in:
- 2019
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- Publication type:
- journal article
Real Driving NOx Emissions and Emission Manipulations of Trucks observed with Plume Chasing.
- Published in:
- Geophysical Research Abstracts, 2019, v. 21, p. 1
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- Publication type:
- Article
Bi-directional genetic modulation of GSK-3β exacerbates hippocampal neuropathology in experimental status epilepticus.
- Published in:
- Cell Death & Disease, 2018, v. 9, n. 10, p. 1, doi. 10.1038/s41419-018-0963-5
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- Publication type:
- Article
The Metabotropic Purinergic P2Y Receptor Family as Novel Drug Target in Epilepsy.
- Published in:
- Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00193
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- Publication type:
- Article
Real Driving NO<sub>x</sub> Emissions of Public Buses in Urban Traffic.
- Published in:
- Geophysical Research Abstracts, 2018, v. 20, p. 8050
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- Publication type:
- Article
Expression and function of the metabotropic purinergic P2Y receptor family in experimental seizure models and patients with drug-refractory epilepsy.
- Published in:
- Epilepsia (Series 4), 2017, v. 58, n. 9, p. 1603, doi. 10.1111/epi.13850
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- Publication type:
- Article
Spatiotemporal progression of ubiquitinproteasome system inhibition after status epilepticus suggests protective adaptation against hippocampal injury.
- Published in:
- Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0163-2
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- Publication type:
- Article
The ATP-Gated P2X7 Receptor As a Target for the Treatment of Drug-Resistant Epilepsy.
- Published in:
- Frontiers in Neuroscience, 2017, v. 10, p. 1, doi. 10.3389/fnins.2017.00021
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- Publication type:
- Article
RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis.
- Published in:
- Scientific Reports, 2017, p. 41517, doi. 10.1038/srep41517
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- Publication type:
- Article
Deletion of the BH3-only protein Noxa alters electrographic seizures but does not protect against hippocampal damage after status epilepticus in mice.
- Published in:
- Cell Death & Disease, 2017, v. 8, n. 1, p. e2556, doi. 10.1038/cddis.2016.301
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- Publication type:
- Article
Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation.
- Published in:
- Human Molecular Genetics, 2016, v. 25, n. 19, p. 4143, doi. 10.1093/hmg/ddw248
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- Publication type:
- Article
Efficacy and safety of bevacizumab plus chemotherapy compared to chemotherapy alone in previously untreated advanced or metastatic colorectal cancer: a systematic review and meta-analysis.
- Published in:
- 2016
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- Publication type:
- journal article
Efficacy and Safety of Combined Androgen Deprivation Therapy (ADT) and Docetaxel Compared with ADT Alone for Metastatic Hormone-Naive Prostate Cancer: A Systematic Review and Meta-Analysis.
- Published in:
- PLoS ONE, 2016, v. 11, n. 6, p. 1, doi. 10.1371/journal.pone.0157660
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- Publication type:
- Article
Critical Evaluation of P2X7 Receptor Antagonists in Selected Seizure Models.
- Published in:
- PLoS ONE, 2016, v. 11, n. 6, p. 1, doi. 10.1371/journal.pone.0156468
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- Publication type:
- Article
Transient P2X7 Receptor Antagonism Produces Lasting Reductions in Spontaneous Seizures and Gliosis in Experimental Temporal Lobe Epilepsy.
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- Journal of Neuroscience, 2016, v. 36, n. 22, p. 5920, doi. 10.1523/JNEUROSCI.4009-15.2016
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- Publication type:
- Article
Bok Is Not Pro-Apoptotic But Suppresses Poly ADP-Ribose Polymerase-Dependent Cell Death Pathways and Protects against Excitotoxic and Seizure-Induced Neuronal Injury.
- Published in:
- Journal of Neuroscience, 2016, v. 36, n. 16, p. 4564, doi. 10.1523/JNEUROSCI.3780-15.2016
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- Publication type:
- Article
Antagomirs targeting microRNA-134 increase hippocampal pyramidal neuron spine volume in vivo and protect against pilocarpine-induced status epilepticus.
- Published in:
- Brain Structure & Function, 2015, v. 220, n. 4, p. 2387, doi. 10.1007/s00429-014-0798-5
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- Publication type:
- Article