Works by Ellis, Lee M.

Results: 71

Sex Representation in Clinical Trials Associated with FDA Cancer Drug Approvals Differs Between Solid and Hematologic Malignancies.

Published in:

Oncologist, 2021, v. 26, n. 2, p. 107, doi. 10.1002/onco.13534

By:

Mendis, Shehara;
Anand, Seerat;
Karasinska, Joanna M.;
Dasari, Arvind;
Unger, Joseph M.;
Gothwal, Anirudh;
Ellis, Lee M.;
Varadhachary, Gauri;
Kopetz, Scott;
Overman, Michael J.;
Raghav, Kanwal;
Loree, Jonathan M.

Publication type:

Article

A Disintegrin and Metalloproteinase Domain 17 Regulates Colorectal Cancer Stem Cells and Chemosensitivity Via Notch1 Signaling.

Published in:

Stem Cells Translational Medicine, 2016, v. 5, n. 3, p. 331, doi. 10.5966/sctm.2015-0168

By:

Wang, Rui;
Ye, Xiangcang;
Bhattacharya, Rajat;
Boulbes, Delphine R.;
Fan, Fan;
Xia, Ling;
Ellis, Lee M.

Publication type:

Article

Combining MEK and SRC inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo.

Published in:

PLoS ONE, 2023, v. 18, n. 3, p. 1, doi. 10.1371/journal.pone.0281063

By:

Fan, Fan;
Ghosh, Susmita;
Powell, Reid;
Roszik, Jason;
Park, Yongsun;
Sobieski, Mary;
Sorokin, Alexey;
Stephan, Clifford;
Kopetz, Scott;
Ellis, Lee M.;
Bhattacharya, Rajat

Publication type:

Article

Endothelial cells activate the cancer stem cell-associated NANOGP8 pathway in colorectal cancer cells in a paracrine fashion.

Published in:

Molecular Oncology, 2017, v. 11, n. 8, p. 1023, doi. 10.1002/1878-0261.12071

By:

Wang, Rui;
Bhattacharya, Rajat;
Ye, Xiangcang;
Fan, Fan;
Boulbes, Delphine R.;
Xia, Ling;
Ellis, Lee M.

Publication type:

Article

miR-203 induces oxaliplatin resistance in colorectal cancer cells by negatively regulating ATM kinase.

Published in:

Molecular Oncology, 2014, v. 8, n. 1, p. 83, doi. 10.1016/j.molonc.2013.09.004

By:

Zhou, Yunfei;
Wan, Guohui;
Spizzo, Riccardo;
Ivan, Cristina;
Mathur, Rohit;
Hu, Xiaoxiao;
Ye, Xiangcang;
Lu, Jia;
Fan, Fan;
Xia, Ling;
Calin, George A.;
Ellis, Lee M.;
Lu, Xiongbin

Publication type:

Article

Intracrine VEGF signalling mediates colorectal cancer cell migration and invasion.

Published in:

British Journal of Cancer, 2017, v. 117, n. 6, p. 848, doi. 10.1038/bjc.2017.238

By:

Bhattacharya, Rajat;
Fan, Fan;
Wang, Rui;
Ye, Xiangcang;
Xia, Ling;
Boulbes, Delphine;
Ellis, Lee M

Publication type:

Article

Intracrine VEGF signalling mediates colorectal cancer cell migration and invasion.

Published in:

2017

By:

Bhattacharya, Rajat;
Fan, Fan;
Wang, Rui;
Ye, Xiangcang;
Xia, Ling;
Boulbes, Delphine;
Ellis, Lee M

Publication type:

journal article

Multiparametric in situ mRNA Hybridization Analysis of Gastric Biopsies Predicts Lymph Node Metastasis in Patients with Gastric Carcinoma.

Published in:

Cancer Science, 2002, v. 93, n. 11, p. 1258, doi. 10.1111/j.1349-7006.2002.tb01232.x

By:

Takahashi, Yutaka;
Kitadai, Yasuhiko;
Ellis, Lee M.;
Bucana, Corazon D.;
Fidler, Isaiah J.;
Mai, Masayoshi

Publication type:

Article

Cancer: The nuances of therapy.

Published in:

Nature, 2009, v. 458, n. 7236, p. 290, doi. 10.1038/458290a

By:

Ellis, Lee M.;
Reardon, David A.

Publication type:

Article

Overall Survival in Phase 3 Clinical Trials and the Surveillance, Epidemiology, and End Results Database in Patients With Metastatic Colorectal Cancer, 1986-2016: A Systematic Review.

Published in:

JAMA Network Open, 2022, v. 5, n. 5, p. e2213588, doi. 10.1001/jamanetworkopen.2022.13588

By:

Shen, Chan;
Tannenbaum, Daniel;
Horn, Robert;
Rogers, Jane;
Eng, Cathy;
Zhou, Shouhao;
Johnson, Benny;
Kopetz, Scott;
Morris, Van;
Overman, Michael;
Parseghian, Christine;
Chang, George J.;
Lopez-Olivo, Maria A.;
Kanwal, Raghav;
Ellis, Lee M.;
Dasari, Arvind

Publication type:

Article

Biology of angiogenesis in tumors of the gastrointestinal tract.

Published in:

Microscopy Research & Technique, 2003, v. 60, n. 2, p. 199, doi. 10.1002/jemt.10258

By:

Reinmuth, Niels;
Parikh, Alexander A.;
Ahmad, Syed A.;
Liu, Wenbiao;
Stoeltzing, Oliver;
Fan, Fan;
Takeda, Akihiko;
Akagi, Morihisa;
Ellis, Lee M.

Publication type:

Article

Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content.

Published in:

2007

By:

McCarty, Marya F.;
Somcio, Ray J.;
Stoeltzing, Oliver;
Wey, Jane;
Fan Fan;
Wenbiao Liu;
Bucana, Corazon;
Ellis, Lee M.;
Fan, Fan;
Liu, Wenbiao

Publication type:

journal article

Cancer-derived small extracellular vesicles promote angiogenesis by heparin-bound, bevacizumab-insensitive VEGF, independent of vesicle uptake.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0609-x

By:

Ko, Song Yi;
Lee, WonJae;
Kenny, Hilary A.;
Dang, Long H.;
Ellis, Lee M.;
Jonasch, Eric;
Lengyel, Ernst;
Naora, Honami

Publication type:

Article

Regulation of Vascular Endothelial Growth Factor Receptor KDR in vitro by a Soluble Factor in Confluent Endothelial Cells.

Published in:

Pathobiology, 1998, v. 66, n. 5, p. 247, doi. 10.1159/000028030

By:

Liu, Wenbiao;
Ellis, Lee M.

Publication type:

Article

Trends in Medical Aid in Dying in Oregon and Washington.

Published in:

JAMA Network Open, 2019, v. 2, n. 8, p. e198648, doi. 10.1001/jamanetworkopen.2019.8648

By:

Al Rabadi, Luai;
LeBlanc, Michael;
Bucy, Taylor;
Ellis, Lee M.;
Hershman, Dawn L.;
Meyskens, Frank L.;
Taylor, Lynne;
Blanke, Charles D.

Publication type:

Article

p53, vessel count, and vascular endothelial growth factor expression in human colon cancer.

Published in:

International Journal of Cancer, 1998, v. 79, n. 1, p. 34, doi. 10.1002/(SICI)1097-0215(19980220)79:1<34::AID-IJC7>3.0.CO;2-X

By:

Takahashi, Yutaka;
Bucana, Corazon D.;
Cleary, Karen R.;
Ellis, Lee M.

Publication type:

Article

A Targeted Approach for Antiangiogenic Therapy of Metastatic Human Colon Cancer.

Published in:

American Surgeon, 2003, v. 69, n. 1, p. 3, doi. 10.1177/000313480306900102

By:

Ellis, Lee M.

Publication type:

Article

Macrophage conditioned medium promotes colorectal cancer stem cell phenotype via the hedgehog signaling pathway.

Published in:

PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0190070

By:

Fan, Fan;
Wang, Rui;
Boulbes, Delphine R.;
Zhang, Huiyuan;
Watowich, Stephanie S.;
Xia, Ling;
Ye, Xiangcang;
Bhattacharya, Rajat;
Ellis, Lee M.

Publication type:

Article

Inhibition of PGE<sub>2</sub>/EP4 receptor signaling enhances oxaliplatin efficacy in resistant colon cancer cells through modulation of oxidative stress.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-40848-4

By:

Huang, Huakang;
Aladelokun, Oladimeji;
Ideta, Takayasu;
Giardina, Charles;
Ellis, Lee M.;
Rosenberg, Daniel W.

Publication type:

Article

Mammalian target of rapamycin is activated in human gastric cancer and serves as a target for therapy in an experimental model.

Published in:

International Journal of Cancer, 2007, v. 120, n. 8, p. 1803, doi. 10.1002/ijc.22442

By:

Lang, Sven A.;
Gaumann, Andreas;
Koehl, Gudrun E.;
Seidel, Ulrike;
Bataille, Frauke;
Klein, Dagmar;
Ellis, Lee M.;
Bolder, Ulrich;
Hofstaedter, Ferdinand;
Schlitt, Hans-Jürgen;
Geissler, Edward K.;
Stoeltzing, Oliver

Publication type:

Article

Production of VEGF165 by Ewing's sarcoma cells induces vasculogenesis and the incorporation of CD34.

Published in:

International Journal of Cancer, 2006, v. 119, n. 4, p. 839, doi. 10.1002/ijc.21916

By:

Lee, Tim H.;
Bolontrade, Marcela F.;
Worth, Laura L.;
Guan, Hui;
Ellis, Lee M.;
Kleinerman, Eugenie S.

Publication type:

Article

Effect of the vascular endothelial growth factor receptor-2 antibody DC101 plus gemcitabine on growth, metastasis and angiogenesis of human pancreatic cancer growing orthotopically in nude mice.

Published in:

International Journal of Cancer, 2002, v. 102, n. 2, p. 101, doi. 10.1002/ijc.10681

By:

Bruns, Christiane J.;
Shrader, Marissa;
Harbison, Matthew T.;
Portera, Charles;
Solorzano, Carmen C.;
Jauch, K.-W.;
Hicklin, Daniel J.;
Radinsky, Robert;
Ellis, Lee M.

Publication type:

Article

Endothelial cell apoptosis is inhibited by a soluble factor secreted by human colon cancer cells.

Published in:

International Journal of Cancer, 2001, v. 92, n. 1, p. 26, doi. 10.1002/1097-0215(200102)9999:9999<::AID-IJC1151>3.0.CO;2-T

By:

Liu, Wenbiao;
Davis, Darren W.;
Ramirez, Karen;
McConkey, David J.;
Ellis, Lee M.

Publication type:

Article

It Is Time to Re-Evaluate the Peer Review Process for Preclinical Research.

Published in:

BioEssays, 2018, v. 40, n. 1, p. n/a, doi. 10.1002/bies.201700185

By:

Bhattacharya, Rajat;
Ellis, Lee M.

Publication type:

Article

Chemotherapeutic drugs?more really is not better.

Published in:

Nature Medicine, 2000, v. 6, n. 5, p. 500, doi. 10.1038/74969

By:

Fidler, Isaiah J.;
Ellis, Lee M.

Publication type:

Article

Inhibition of tumour invasion and angiogenesis by epigallocatechin gallate (EGCG), a major component of green tea.

Published in:

International Journal of Experimental Pathology, 2001, v. 82, n. 6, p. 309, doi. 10.1046/j.1365-2613.2001.00205.x

By:

Jung, Young D.;
Ellis, Lee M.

Publication type:

Article

Expression of Interferon-β is Associated with Growth Arrest of Murine and Human Epidermal Cells.

Published in:

Journal of Investigative Dermatology, 1999, v. 112, n. 5, p. 802, doi. 10.1046/j.1523-1747.1999.00566.x

By:

Bielenberg, Diane R.;
McCarty, Marya F.;
Bucana, Corazon D.;
Yuspa, Stuart H.;
Morgan, David;
Arbeit, Jeffrey M.;
Ellis, Lee M.;
Cleary, Karen R.;
Fidler, Isaiah J.

Publication type:

Article

Tumor Sidedness, Recurrence, and Survival After Curative Resection of Localized Colon Cancer.

Published in:

2021

By:

Malakorn, Songphol;
Ouchi, Akira;
Hu, Chung-Yuan;
Sandhu, Lakhbir;
Dasari, Arvind;
You, Yi-Qian Nancy;
Kopetz, E Scott;
Ellis, Lee M;
Chang, George J

Publication type:

journal article

VEGF-targeted therapy: mechanisms of anti-tumour activity.

Published in:

Nature Reviews Cancer, 2008, v. 8, n. 8, p. 579, doi. 10.1038/nrc2403

By:

Ellis, Lee M.;
Hicklin, Daniel J.

Publication type:

Article

Functional significance of VEGFR-2 on ovarian cancer cells.

Published in:

International Journal of Cancer, 2009, v. 124, n. 5, p. 1045, doi. 10.1002/ijc.24028

By:

Spannuth, Whitney A.;
Nick, Alpa M.;
Jennings, Nicholas B.;
Armaiz-Pena, Guillermo N.;
Mangala, Lingegowda S.;
Danes, Christopher G.;
Lin, Yvonne G.;
Merritt, William M.;
Thaker, Premal H.;
Kamat, Aparna A.;
Han, Liz Y.;
Tonra, James R.;
Coleman, Robert L.;
Ellis, Lee M.;
Sood, Anil K.

Publication type:

Article

Effect of different types of smoking and synergism with hepatitis C virus on risk of hepatocellular carcinoma in American men and women: Case-control study.

Published in:

International Journal of Cancer, 2008, v. 123, n. 8, p. 1883, doi. 10.1002/ijc.23730

By:

Hassan, Manal M.;
Spitz, Margaret R.;
Thomas, Melanie B.;
El-Deeb, Adel S.;
Glover, Katrina Y.;
Nguyen, Nga T.;
Chan, Wenyaw;
Kaseb, Ahmed;
Curley, Steven A.;
Vauthey, Jean-Nicolas;
Ellis, Lee M.;
Abdalla, Eddie;
Lozano, Richard D.;
Patt, Yehuda Z.;
Brown, Thomas D.;
Abbruzzese, James L.;
Li, Donghui

Publication type:

Article

Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS -mutated colorectal cancer.

Published in:

Therapeutic Advances in Medical Oncology, 2024, p. 1, doi. 10.1177/17588359241303302

By:

Ghosh, Susmita;
Fan, Fan;
Powell, Reid;
Park, Yong Sung;
Stephan, Clifford;
Kopetz, E. Scott;
Ellis, Lee M.;
Bhattacharya, Rajat

Publication type:

Article

Words matter: Restoring respect and dignity when referring to individuals with cancer.

Published in:

2017

By:

Ellis, Lee M.;
Blanke, Charles D.;
Kohn, Elise C.

Publication type:

journal article

Identification of polymorphisms in ultraconserved elements associated with clinical outcomes in locally advanced colorectal adenocarcinoma.

Published in:

Cancer (0008543X), 2012, v. 118, n. 24, p. 6188, doi. 10.1002/cncr.27653

By:

Lin, Moubin;
Eng, Cathy;
Hawk, Ernest T.;
Huang, Maosheng;
Lin, Jie;
Gu, Jian;
Ellis, Lee M.;
Wu, Xifeng

Publication type:

Article

Role for the double-stranded RNA activated protein kinase PKR in E2F-1-induced apoptosis.

Published in:

Oncogene, 2002, v. 21, n. 41, p. 6278, doi. 10.1038/sj.onc.1205761

By:

Virburger, Stephan A.;
Pataer, Abujiang;
Yoshida, Kazumi;
Barber, Glen N.;
Weiya Xia;
Chiao, Paul;
Ellis, Lee M.;
Mien-Chie Hung;
Swisher, Stephen G.;
Hunt, Kelly K.

Publication type:

Article

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis.

Published in:

Oncogene, 2002, v. 21, n. 13, p. 2000, doi. 10.1038/sj.onc.1205260

By:

Niu, Guilian;
Wright, Kenneth L.;
Huang, Mei;
Song, Lanxi;
Haura, Eric;
Turkson, James;
Shumin Zhang;
Wang, Tianhong;
Sinibaldi, Dominic;
Coppola, Domenico;
Heller, Richard;
Ellis, Lee M.;
Karras, James;
Bromberg, Jacqueline;
Pardoll, Drew;
Jove, Richard;
Hua Yu

Publication type:

Article

Cytospin-A Regulates Colorectal Cancer Cell Division and Migration by Modulating Stability of Microtubules and Actin Filaments.

Published in:

Cancers, 2022, v. 14, n. 8, p. 1977, doi. 10.3390/cancers14081977

By:

Fan, Fan;
Roszik, Jason;
Xia, Ling;
Ghosh, Susmita;
Wang, Rui;
Ye, Xiangcang;
Hawke, David;
Ellis, Lee M.;
Bhattacharya, Rajat

Publication type:

Article

Vascular endothelial growth factor is an in vivo survival factor for tumor endothelium in a murine model of colorectal carcinoma liver metastases.

Published in:

Cancer (0008543X), 2000, v. 89, n. 3, p. 488, doi. 10.1002/1097-0142(20000801)89:3<488::AID-CNCR3>3.0.CO;2-X

By:

Bruns, Christiane J.;
Liu, Wenbiao;
Davis, Darren W.;
Shaheen, Raymond M.;
McConkey, David J.;
Wilson, Michael R.;
Bucana, Corazon D.;
Hicklin, Daniel J.;
Ellis, Lee M.

Publication type:

Article

Carcinoid tumors of the rectum.

Published in:

Cancer (0008543X), 1997, v. 79, n. 7, p. 1294, doi. 10.1002/(SICI)1097-0142(19970401)79:7<1294::AID-CNCR4>3.0.CO;2-H

By:

Koura, Aaryan N.;
Giacco, Geoffrey G.;
Curley, Steven A.;
Skibber, John M.;
Feig, Barry W.;
Ellis, Lee M.

Publication type:

Article

Gastrointestinal leiomyosarcoma metastatic to the liver. Durable tumor regression by hepatic chemoembolization infusion with cisplatin and vinblastine.

Published in:

1995

By:

Mavligit, Giora M.;
Zukwiski, Alexander A.;
Ellis, Lee M.;
Chuang, Vincent P.;
Wallace, Sidney;
Mavligit, G M;
Zukwiski, A A;
Ellis, L M;
Chuang, V P;
Wallace, S

Publication type:

journal article

Influence of surgical margins on outcome in patients with preoperatively irradiated extremity soft tissue sarcomas.

Published in:

1994

By:

Tanabe, Kenneth K.;
Pollock, Raphael E.;
Ellis, Lee M.;
Murphy, Anne;
Sherman, Neil;
Romsdahl, Marvin M.;
Tanabe, K K;
Pollock, R E;
Ellis, L M;
Murphy, A;
Sherman, N;
Romsdahl, M M

Publication type:

journal article

Finding the tumor copycat: Therapy fails, patients don't.

Published in:

Nature Medicine, 2010, v. 16, n. 9, p. 974, doi. 10.1038/nm0910-974

By:

Ellis, Lee M.;
Fidler, Isaiah J.

Publication type:

Article

Bevacizumab.

Published in:

Nature Reviews Drug Discovery, 2005, v. 4, p. S8, doi. 10.1038/nrd1727

By:

Ellis, Lee M.;
Kirkpatrick, Peter

Publication type:

Article

Analysis of LGR4 Receptor Distribution in Human and Mouse Tissues.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0078144

By:

Yi, Jing;
Xiong, Wei;
Gong, Xing;
Bellister, Seth;
Ellis, Lee M.;
Liu, Qingyun

Publication type:

Article

Generation of Monoclonal Antibody MS17-57 Targeting Secreted Alkaline Phosphatase Ectopically Expressed on the Surface of Gastrointestinal Cancer Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077398

By:

Li, Ming;
Gao, Jianpeng;
Feng, Runhua;
Wang, Yuling;
Chen, Xuehua;
Sun, Jianyu;
Zhang, Dongqing;
Zhu, Zhenggang;
Ellis, Lee M.;
Lu, Mason;
Lee, Jeffrey E.;
Feng, Zhenqing;
Liu, Bingya

Publication type:

Article

A Survey on Data Reproducibility in Cancer Research Provides Insights into Our Limited Ability to Translate Findings from the Laboratory to the Clinic

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063221

By:

Mobley, Aaron;
Linder, Suzanne K.;
Braeuer, Russell;
Ellis, Lee M.;
Zwelling, Leonard

Publication type:

Article

Neuropilin-2 Mediated b-Catenin Signaling and Survival in Human Gastro-Intestinal Cancer Cell Lines.

Published in:

PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0023208

By:

Samuel, Shaija;
Gaur, Puja;
Fan, Fan;
Xia, Ling;
Gray, Michael J.;
Dallas, Nikolaos A.;
Bose, Debashish;
Rodriguez-Aguayo, Cristian;
Lopez-Berestein, Gabriel;
Plowman, Greg;
Bagri, Anil;
Sood, Anil K.;
Ellis, Lee M.

Publication type:

Article

Drug development: Raise standards for preclinical cancer research.

Published in:

2012

By:

Begley, C. Glenn;
Ellis, Lee M.

Publication type:

Opinion

Therapeutic Targeting of Neuropilin-2 on Colorectal Carcinoma Cells Implanted in the Murine Liver.

Published in:

JNCI: Journal of the National Cancer Institute, 2008, v. 100, n. 2, p. 109, doi. 10.1093/jnci/djm279

By:

Gray, Michael J.;
Van Buren, George;
Dallas, Nikolaos A.;
Ling Xia;
Xuemei Wang;
Yang, Anthony D.;
Somcio, Ray J.;
Lin, Yvonne G.;
Lim, Sherry;
Fan Fan;
Mangala, Lingegowda S.;
Arumugam, Thiruvengadam;
Logsdon, Craig D.;
Lopez-Berestein, Gabriel;
Sood, Anil K.;
Ellis, Lee M.

Publication type:

Article

GWAS-identified colorectal cancer susceptibility loci associated with clinical outcomes.

Published in:

Carcinogenesis, 2012, v. 33, n. 7, p. 1327, doi. 10.1093/carcin/bgs147

By:

Dai, Jingyao;
Gu, Jian;
Huang, Maosheng;
Eng, Cathy;
Kopetz, E.Scott;
Ellis, Lee M.;
Hawk, Ernest;
Wu, Xifeng

Publication type:

Article