Works by Ellerby, Lisa M.

Results: 31

Correction to: N-Propargylglycine: a unique suicide inhibitor of proline dehydrogenase with anticancer activity and brain-enhancing mitohormesis properties.

Published in:

2021

By:

Scott, Gary K.;
Mahoney, Sophia;
Scott, Madeleine;
Loureiro, Ashley;
Lopez-Ramirez, Alejandro;
Tanner, John J.;
Ellerby, Lisa M.;
Benz, Christopher C.

Publication type:

Correction Notice

N-Propargylglycine: a unique suicide inhibitor of proline dehydrogenase with anticancer activity and brain-enhancing mitohormesis properties.

Published in:

Amino Acids, 2021, v. 53, n. 12, p. 1927, doi. 10.1007/s00726-021-03012-9

By:

Scott, Gary K.;
Mahoney, Sophia;
Scott, Madeleine;
Loureiro, Ashley;
Lopez-Ramirez, Alejandro;
Tanner, John J.;
Ellerby, Lisa M.;
Benz, Christopher C.

Publication type:

Article

Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity.

Published in:

Genome Biology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s13059-021-02301-6

By:

Sorek, Matan;
Oweis, Walaa;
Nissim-Rafinia, Malka;
Maman, Moria;
Simon, Shahar;
Hession, Cynthia C.;
Adiconis, Xian;
Simmons, Sean K.;
Sanjana, Neville E.;
Shi, Xi;
Lu, Congyi;
Pan, Jen Q.;
Xu, Xiaohong;
Pouladi, Mahmoud A.;
Ellerby, Lisa M.;
Zhang, Feng;
Levin, Joshua Z.;
Meshorer, Eran

Publication type:

Article

A second cytotoxic proteolytic peptide derived from amyloid β-protein precursor.

Published in:

Nature Medicine, 2000, v. 6, n. 4, p. 397, doi. 10.1038/74656

By:

Lu, Daniel C.;
Rabizadeh, Shahrooz;
Chandra, Sreeganga;
Shayya, Rana F.;
Ellerby, Lisa M.;
Ye, Xin;
Salvesen, Guy S.;
Koo, Edward H.;
Bredesen, Dale E.

Publication type:

Article

Anti-cancer activity of targeted pro-apoptotic peptides.

Published in:

Nature Medicine, 1999, v. 5, n. 9, p. 1032, doi. 10.1038/12469

By:

Ellerby, H. Michael;
Arap, Wadih;
Ellerby, Lisa M.;
Kain, Renate;
Andrusiak, Rebecca;
Rio, Gabriel Del;
Krajewski, Stanislaw;
Lombardo, Christian R.;
Rao, Rammohan;
Ruoslahti, Erkki;
Bredesen, Dale E.;
Pasqualini, Renata

Publication type:

Article

Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.65979

By:

Cirnaru, Maria-Daniela;
Sicheng Song;
Tshilenge, Kizito-Tshitoko;
Chuhyon Corwin;
Mleczko, Justyna;
Aguirre, Carlos Galicia;
Benlhabib, Houda;
Bendl, Jaroslav;
Apontes, Pasha;
Fullard, John;
Creus-Muncunill, Jordi;
Reyahi, Azadeh;
Nik, Ali M.;
Carlsson, Peter;
Roussos, Panos;
Mooney, Sean D.;
Ellerby, Lisa M.;
Ehrlich, Michelle E.

Publication type:

Article

Structural Evaluation of a Novel Pro-apoptotic Peptide Coupled to CNGRC Tumor Homing Sequence by NMR.

Published in:

Chemical Biology & Drug Design, 2006, v. 67, n. 6, p. 417, doi. 10.1111/j.1747-0285.2006.00394.x

By:

Sandoval, Cristina M.;
Geierstanger, Bernhard H.;
Fujimura, Satoshi;
Balatbat, Calvin;
Williams, Taylor;
de Unamuno, Julio;
Whiles-Lillig, Jennifer A.;
Ellerby, Lisa M.;
Michael Ellerby, H.;
Jennings, Patricia;
Plesniak, Leigh A.

Publication type:

Article

Proteolytic cleavage of ataxin-7 promotes SCA7 retinal degeneration and neurological dysfunction.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 14, p. 3908, doi. 10.1093/hmg/ddv121

By:

Guyenet, Stephan J.;
Mookerjee, Shona S.;
Lin, Amy;
Custer, Sara K.;
Chen, Sylvia F.;
Sopher, Bryce L.;
La Spada, Albert R.;
Ellerby, Lisa M.

Publication type:

Article

Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels.

Published in:

Autophagy, 2021, v. 17, n. 12, p. 4119, doi. 10.1080/15548627.2021.1904489

By:

Bailus, Barbara J.;
Scheeler, Stephen M.;
Simons, Jesse;
Sanchez, Maria A.;
Tshilenge, Kizito-Tshitoko;
Creus-Muncunill, Jordi;
Naphade, Swati;
Lopez-Ramirez, Alejandro;
Zhang, Ningzhe;
Lakshika Madushani, Kuruwitage;
Moroz, Stanislav;
Loureiro, Ashley;
Schreiber, Katherine H.;
Hausch, Felix;
Kennedy, Brian K.;
Ehrlich, Michelle E.;
Ellerby, Lisa M.

Publication type:

Article

Caspase-6 Activity in a BACHD Mouse Modulates Steady-State Levels of Mutant Huntingtin Protein But Is Not Necessary for Production of a 586 Amino Acid Proteolytic Fragment.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 22, p. 7454, doi. 10.1523/JNEUROSCI.6379-11.2012

By:

Gafni, Juliette;
Papanikolaou, Theodora;
DeGiacomo, Francesco;
Holcomb, Jennifer;
Sylvia Chen;
Menalled, Liliana;
Kudwa, Andrea;
Fitzpatrick, Jon;
Miller, Sam;
Ramboz, Sylvie;
Tuunanen, Pasi I.;
Lehtimäki, Kimmo K.;
Yang, X. William;
Larry Park;
Seung Kwak;
Howland, David;
Hyunsun Park;
Ellerby, Lisa M.

Publication type:

Article

Polyglutamine Disease Modeling: Epitope Based Screen for Homologous Recombination using CRISPR/Cas9 System.

Published in:

PLoS Currents, 2014, p. 369, doi. 10.1371/currents.hd.0242d2e7ad72225efa72f6964589369a

By:

An, Mahru C.;
O'Brien, Robert N.;
Ningzhe Zhang;
Patra, Biranchi N.;
De La Cruz, Michael;
Ray, Animesh;
Ellerby, Lisa M.

Publication type:

Article

Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78

Published in:

FEBS Letters, 2002, v. 514, n. 2/3, p. 122, doi. 10.1016/S0014-5793(02)02289-5

By:

Rao, Rammohan V.;
Peel, Alyson;
Logvinova, Anna;
del Rio, Gabriel;
Hermel, Evan;
Yokota, Takanori;
Goldsmith, Paul C.;
Ellerby, Lisa M.;
Ellerby, H. Michael;
Bredesen, Dale E.

Publication type:

Article

Do posttranslational modifications of CuZnSOD lead to sporadic amyotrophic lateral sclerosis?

Published in:

Annals of Neurology, 1997, v. 42, n. 2, p. 135, doi. 10.1002/ana.410420202

By:

Bredesen, Dale E.;
Ellerby, Lisa M.;
Hart, P. John;
Wiedau-Pazos, Martina;
Valentine, Joan Selverstone

Publication type:

Article

TYROBP/DAP12 knockout in Huntington's disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterioration.

Published in:

Journal of Neuroinflammation, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12974-024-03052-4

By:

Creus-Muncunill, Jordi;
Haure-Mirande, Jean Vianney;
Mattei, Daniele;
Bons, Joanna;
Ramirez, Angie V.;
Hamilton, B. Wade;
Corwin, Chuhyon;
Chowdhury, Sarah;
Schilling, Birgit;
Ellerby, Lisa M.;
Ehrlich, Michelle E.

Publication type:

Article

Histone deacetylase-3 interacts with ataxin-7 and is altered in a spinocerebellar ataxia type 7 mouse model.

Published in:

Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-42

By:

Duncan, Carlotta E.;
An, Mahru C.;
Papanikolaou, Theodora;
Rugani, Caitlin;
Vitelli, Cathy;
Ellerby, Lisa M.

Publication type:

Article

Mitochondrial dysfunction in Huntington’s disease: the bioenergetics of isolated and in situ mitochondria from transgenic mice.

Published in:

Journal of Neurochemistry, 2007, v. 101, n. 1, p. 241, doi. 10.1111/j.1471-4159.2006.04361.x

By:

Oliveira, Jorge M. A.;
Jekabsons, Mika B.;
Chen, Sylvia;
Lin, Amy;
Rego, A. Cristina;
Gonçalves, Jorge;
Ellerby, Lisa M.;
Nicholls, David G.

Publication type:

Article

Caspase-mediated proteolysis of the polyglutamine disease protein ataxin-3.

Published in:

Journal of Neurochemistry, 2004, v. 89, n. 4, p. 908, doi. 10.1111/j.1471-4159.2004.02369.x

By:

Berke, Sarah J. Shoesmith;
Schmied, Francisca A. Flores;
Brunt, Ewout R.;
Ellerby, Lisa M.;
Paulson, Henry L.

Publication type:

Article

Kennedy's Disease: Caspase Cleavage of the Androgen Receptor Is aCrucial Event in Cytotoxicity.

Published in:

Journal of Neurochemistry, 1999, v. 72, n. 1, p. 185, doi. 10.1046/j.1471-4159.1999.0720185.x

By:

Ellerby, Lisa M.;
Hackam, Abigail S.;
Propp, Stephanie S.;
Ellerby, H. Michael;
Rabizadeh, Shahrooz;
Cashman, Neil R.;
Trifiro, Mark A.;
Pinsky, Leonard;
Wellington, Cheryl L.;
Salvesen, Guy S.;
Hayden, Michael R.;
Bredesen, Dale E.

Publication type:

Article

Shift of the Cellular Oxidation-Reduction Potential in Neural Cells Expressing Bcl-2.

Published in:

Journal of Neurochemistry, 1996, v. 67, n. 3, p. 1259, doi. 10.1046/j.1471-4159.1996.67031259.x

By:

Ellerby, Lisa M.;
Ellerby, H. Michael;
Park, Sunghi M.;
Holleran, Anne L.;
Murphy, Anne N.;
Fiskum, Gary;
Kane, Darci J.;
Testa, Maria P.;
Kayalar, Celik;
Bredesen, Dale E.

Publication type:

Article

Altered Expression of Matrix Metalloproteinases and Their Endogenous Inhibitors in a Human Isogenic Stem Cell Model of Huntington's Disease.

Published in:

Frontiers in Neuroscience, 2018, p. 1, doi. 10.3389/fnins.2017.00736

By:

Naphade, Swati;
Embusch, Alexander;
Madushani, Kuruwitage Lakshika;
Ring, Karen L.;
Ellerby, Lisa M.

Publication type:

Article

Autophagy.

Published in:

Autophagy, 2010, v. 6, n. 2, p. 312, doi. 10.4161/auto.6.2.11139

By:

Duncan, Carlotta;
Papanikolaou, Theodora;
Ellerby, Lisa M.

Publication type:

Article

Novel probes for label-free detection of neurodegenerative GGGGCC repeats associated with amyotrophic lateral sclerosis.

Published in:

Analytical & Bioanalytical Chemistry, 2019, v. 411, n. 26, p. 6995, doi. 10.1007/s00216-019-02075-8

By:

Taki, Motahareh;
Rohilla, Kushal J.;
Barton, Maria;
Funneman, Madison;
Benzabeh, Najiyah;
Naphade, Swati;
Ellerby, Lisa M.;
Gagnon, Keith T.;
Shamsi, Mohtashim H.

Publication type:

Article

Striatal Cholinergic Dysregulation after Neonatal Decrease in X‐Linked Dystonia Parkinsonism‐Related TAF1 Isoforms.

Published in:

Movement Disorders, 2021, v. 36, n. 12, p. 2780, doi. 10.1002/mds.28750

By:

Cirnaru, Maria‐Daniela;
Creus‐Muncunill, Jordi;
Nelson, Shareen;
Lewis, Travis B.;
Watson, Jaime;
Ellerby, Lisa M.;
Gonzalez‐Alegre, Pedro;
Ehrlich, Michelle E.

Publication type:

Article

Postnatal Conditional Deletion of Bcl11b in Striatal Projection Neurons Mimics the Transcriptional Signature of Huntington's Disease.

Published in:

Biomedicines, 2022, v. 10, n. 10, p. N.PAG, doi. 10.3390/biomedicines10102377

By:

Song, Sicheng;
Creus Muncunill, Jordi;
Galicia Aguirre, Carlos;
Tshilenge, Kizito-Tshitoko;
Hamilton, B. Wade;
Gerencser, Akos A.;
Benlhabib, Houda;
Cirnaru, Maria-Daniela;
Leid, Mark;
Mooney, Sean D.;
Ellerby, Lisa M.;
Ehrlich, Michelle E.

Publication type:

Article

Neurodegenerative disease: Cut to the chase.

Published in:

Nature, 2006, v. 442, n. 7103, p. 641, doi. 10.1038/442641a

By:

Ellerby, Lisa M.;
Orr, Harry T.

Publication type:

Article

FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16<sup>INK4a</sup> increase.

Published in:

Aging Cell, 2020, v. 19, n. 11, p. 1, doi. 10.1111/acel.13226

By:

Voisin, Jessica;
Farina, Francesca;
Naphade, Swati;
Fontaine, Morgane;
Tshilenge, Kizito‐Tshitoko;
Galicia Aguirre, Carlos;
Lopez‐Ramirez, Alejandro;
Dancourt, Julia;
Ginisty, Aurélie;
Sasidharan Nair, Satish;
Lakshika Madushani, Kuruwitage;
Zhang, Ningzhe;
Lejeune, François‐Xavier;
Verny, Marc;
Campisi, Judith;
Ellerby, Lisa M.;
Neri, Christian

Publication type:

Article

Posttranslational Modification of Ataxin-7 at Lysine 257 Prevents Autophagy-Mediated Turnover of an N-Terminal Caspase-7 Cleavage Fragment.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 48, p. 15134, doi. 10.1523/JNEUROSCI.4720-09.2009

By:

Mookerjee, Shona;
Papanikolaou, Theodora;
Guyenet, Stephan J.;
Sampath, Vanitha;
Lin, Amy;
Vitelli, Cathy;
DeGiacomo, Francesco;
Sopher, Bryce L.;
Chen, Sylvia F.;
La Spada, Albert R.;
Ellerby, Lisa M.

Publication type:

Article

Polyglutamine-Expanded Androgen Receptor Truncation Fragments Activate a Bax-Dependent Apoptotic Cascade Mediated by DP5/Hrk.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 7, p. 1987, doi. 10.1523/JNEUROSCI.4072-08.2009

By:

Young, Jessica E.;
Garden, Gwenn A.;
Martinez, Refugio A.;
Tanaka, Fumiaki;
Sandoval, C. Miguel;
Smith, Annette C.;
Sopher, Bryce L.;
Lin, Amy;
Fischbeck, Kenneth H.;
Ellerby, Lisa M.;
Morrison, Richard S.;
Taylor, J. Paul;
La Spada, Albert R.

Publication type:

Article

Mitochondrial-Dependent Ca<sup>2+</sup> Handling in Huntington's Disease Striatal Cells: Effect of Histone Deacetylase Inhibitors.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 43, p. 11174, doi. 10.1523/JNEUROSCI.3004-06.2006

By:

Oliveira, Jorge M. A.;
Chen, Sylvia;
Almeida, Sandra;
Riley, Rebeccah;
Gonçalves, Jorge;
Oliveira, Catarina R.;
Hayden, Michael R.;
Nicholls, David G.;
Ellerby, Lisa M.;
Rego, A. Christina

Publication type:

Article

A Genome-Scale RNA--Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington's Disease.

Published in:

PLoS Genetics, 2012, v. 8, n. 11, p. 1, doi. 10.1371/journal.pgen.1003042

By:

Miller, John P.;
Yates, Bridget E.;
Al-Ramahi, Ismael;
Berman, Ari E.;
Sanhueza, Mario;
Kim, Eugene;
de Haro, Maria;
DeGiacomo, Francesco;
Torcassi, Cameron;
Holcomb, Jennifer;
Gafni, Juliette;
Mooney, Sean D.;
Botas, Juan;
Ellerby, Lisa M.;
Hughes, Robert E.

Publication type:

Article

Huntingtin Interacting Proteins Are Genetic Modifiers of Neurodegeneration.

Published in:

PLoS Genetics, 2007, v. 3, n. 5, p. e82, doi. 10.1371/journal.pgen.0030082

By:

Kaltenbach, Linda S.;
Romero, Eliana;
Becklin, Robert R.;
Chettier, Rakesh;
Bell, Russell;
Phansalkar, Amit;
Strand, Andrew;
Torcassi, Cameron;
Savage, Justin;
Hurlburt, Anthony;
Guang-Ho Cha;
Ukani, Lubna;
Chepanoske, Cindy Lou;
Yuejun Zhen;
Sahasrabudhe, Sudhir;
Olson, James;
Kurschner, Cornelia;
Ellerby, Lisa M.;
Peltier, John M.;
Botas, Juan

Publication type:

Article