Works by Ellerby, Lisa M.

Results: 31

Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78
Published in:
FEBS Letters, 2002, v. 514, n. 2/3, p. 122, doi. 10.1016/S0014-5793(02)02289-5
By:
- Rao, Rammohan V.;
- Peel, Alyson;
- Logvinova, Anna;
- del Rio, Gabriel;
- Hermel, Evan;
- Yokota, Takanori;
- Goldsmith, Paul C.;
- Ellerby, Lisa M.;
- Ellerby, H. Michael;
- Bredesen, Dale E.
Publication type:
Article
Caspase-mediated proteolysis of the polyglutamine disease protein ataxin-3.
Published in:
Journal of Neurochemistry, 2004, v. 89, n. 4, p. 908, doi. 10.1111/j.1471-4159.2004.02369.x
By:
- Berke, Sarah J. Shoesmith;
- Schmied, Francisca A. Flores;
- Brunt, Ewout R.;
- Ellerby, Lisa M.;
- Paulson, Henry L.
Publication type:
Article
Kennedy's Disease: Caspase Cleavage of the Androgen Receptor Is aCrucial Event in Cytotoxicity.
Published in:
Journal of Neurochemistry, 1999, v. 72, n. 1, p. 185, doi. 10.1046/j.1471-4159.1999.0720185.x
By:
- Ellerby, Lisa M.;
- Hackam, Abigail S.;
- Propp, Stephanie S.;
- Ellerby, H. Michael;
- Rabizadeh, Shahrooz;
- Cashman, Neil R.;
- Trifiro, Mark A.;
- Pinsky, Leonard;
- Wellington, Cheryl L.;
- Salvesen, Guy S.;
- Hayden, Michael R.;
- Bredesen, Dale E.
Publication type:
Article
Shift of the Cellular Oxidation-Reduction Potential in Neural Cells Expressing Bcl-2.
Published in:
Journal of Neurochemistry, 1996, v. 67, n. 3, p. 1259, doi. 10.1046/j.1471-4159.1996.67031259.x
By:
- Ellerby, Lisa M.;
- Ellerby, H. Michael;
- Park, Sunghi M.;
- Holleran, Anne L.;
- Murphy, Anne N.;
- Fiskum, Gary;
- Kane, Darci J.;
- Testa, Maria P.;
- Kayalar, Celik;
- Bredesen, Dale E.
Publication type:
Article
Neurodegenerative disease: Cut to the chase.
Published in:
Nature, 2006, v. 442, n. 7103, p. 641, doi. 10.1038/442641a
By:
- Ellerby, Lisa M.;
- Orr, Harry T.
Publication type:
Article
Postnatal Conditional Deletion of Bcl11b in Striatal Projection Neurons Mimics the Transcriptional Signature of Huntington's Disease.
Published in:
Biomedicines, 2022, v. 10, n. 10, p. N.PAG, doi. 10.3390/biomedicines10102377
By:
- Song, Sicheng;
- Creus Muncunill, Jordi;
- Galicia Aguirre, Carlos;
- Tshilenge, Kizito-Tshitoko;
- Hamilton, B. Wade;
- Gerencser, Akos A.;
- Benlhabib, Houda;
- Cirnaru, Maria-Daniela;
- Leid, Mark;
- Mooney, Sean D.;
- Ellerby, Lisa M.;
- Ehrlich, Michelle E.
Publication type:
Article
Novel probes for label-free detection of neurodegenerative GGGGCC repeats associated with amyotrophic lateral sclerosis.
Published in:
Analytical & Bioanalytical Chemistry, 2019, v. 411, n. 26, p. 6995, doi. 10.1007/s00216-019-02075-8
By:
- Taki, Motahareh;
- Rohilla, Kushal J.;
- Barton, Maria;
- Funneman, Madison;
- Benzabeh, Najiyah;
- Naphade, Swati;
- Ellerby, Lisa M.;
- Gagnon, Keith T.;
- Shamsi, Mohtashim H.
Publication type:
Article
Histone deacetylase-3 interacts with ataxin-7 and is altered in a spinocerebellar ataxia type 7 mouse model.
Published in:
Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-42
By:
- Duncan, Carlotta E.;
- An, Mahru C.;
- Papanikolaou, Theodora;
- Rugani, Caitlin;
- Vitelli, Cathy;
- Ellerby, Lisa M.
Publication type:
Article
Mitochondrial dysfunction in Huntington’s disease: the bioenergetics of isolated and in situ mitochondria from transgenic mice.
Published in:
Journal of Neurochemistry, 2007, v. 101, n. 1, p. 241, doi. 10.1111/j.1471-4159.2006.04361.x
By:
- Oliveira, Jorge M. A.;
- Jekabsons, Mika B.;
- Chen, Sylvia;
- Lin, Amy;
- Rego, A. Cristina;
- Gonçalves, Jorge;
- Ellerby, Lisa M.;
- Nicholls, David G.
Publication type:
Article
A second cytotoxic proteolytic peptide derived from amyloid β-protein precursor.
Published in:
Nature Medicine, 2000, v. 6, n. 4, p. 397, doi. 10.1038/74656
By:
- Lu, Daniel C.;
- Rabizadeh, Shahrooz;
- Chandra, Sreeganga;
- Shayya, Rana F.;
- Ellerby, Lisa M.;
- Ye, Xin;
- Salvesen, Guy S.;
- Koo, Edward H.;
- Bredesen, Dale E.
Publication type:
Article
Anti-cancer activity of targeted pro-apoptotic peptides.
Published in:
Nature Medicine, 1999, v. 5, n. 9, p. 1032, doi. 10.1038/12469
By:
- Ellerby, H. Michael;
- Arap, Wadih;
- Ellerby, Lisa M.;
- Kain, Renate;
- Andrusiak, Rebecca;
- Rio, Gabriel Del;
- Krajewski, Stanislaw;
- Lombardo, Christian R.;
- Rao, Rammohan;
- Ruoslahti, Erkki;
- Bredesen, Dale E.;
- Pasqualini, Renata
Publication type:
Article
Structural Evaluation of a Novel Pro-apoptotic Peptide Coupled to CNGRC Tumor Homing Sequence by NMR.
Published in:
Chemical Biology & Drug Design, 2006, v. 67, n. 6, p. 417, doi. 10.1111/j.1747-0285.2006.00394.x
By:
- Sandoval, Cristina M.;
- Geierstanger, Bernhard H.;
- Fujimura, Satoshi;
- Balatbat, Calvin;
- Williams, Taylor;
- de Unamuno, Julio;
- Whiles-Lillig, Jennifer A.;
- Ellerby, Lisa M.;
- Michael Ellerby, H.;
- Jennings, Patricia;
- Plesniak, Leigh A.
Publication type:
Article
Do posttranslational modifications of CuZnSOD lead to sporadic amyotrophic lateral sclerosis?
Published in:
Annals of Neurology, 1997, v. 42, n. 2, p. 135, doi. 10.1002/ana.410420202
By:
- Bredesen, Dale E.;
- Ellerby, Lisa M.;
- Hart, P. John;
- Wiedau-Pazos, Martina;
- Valentine, Joan Selverstone
Publication type:
Article
TYROBP/DAP12 knockout in Huntington's disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterioration.
Published in:
Journal of Neuroinflammation, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12974-024-03052-4
By:
- Creus-Muncunill, Jordi;
- Haure-Mirande, Jean Vianney;
- Mattei, Daniele;
- Bons, Joanna;
- Ramirez, Angie V.;
- Hamilton, B. Wade;
- Corwin, Chuhyon;
- Chowdhury, Sarah;
- Schilling, Birgit;
- Ellerby, Lisa M.;
- Ehrlich, Michelle E.
Publication type:
Article
A Genome-Scale RNA--Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington's Disease.
Published in:
PLoS Genetics, 2012, v. 8, n. 11, p. 1, doi. 10.1371/journal.pgen.1003042
By:
- Miller, John P.;
- Yates, Bridget E.;
- Al-Ramahi, Ismael;
- Berman, Ari E.;
- Sanhueza, Mario;
- Kim, Eugene;
- de Haro, Maria;
- DeGiacomo, Francesco;
- Torcassi, Cameron;
- Holcomb, Jennifer;
- Gafni, Juliette;
- Mooney, Sean D.;
- Botas, Juan;
- Ellerby, Lisa M.;
- Hughes, Robert E.
Publication type:
Article
Huntingtin Interacting Proteins Are Genetic Modifiers of Neurodegeneration.
Published in:
PLoS Genetics, 2007, v. 3, n. 5, p. e82, doi. 10.1371/journal.pgen.0030082
By:
- Kaltenbach, Linda S.;
- Romero, Eliana;
- Becklin, Robert R.;
- Chettier, Rakesh;
- Bell, Russell;
- Phansalkar, Amit;
- Strand, Andrew;
- Torcassi, Cameron;
- Savage, Justin;
- Hurlburt, Anthony;
- Guang-Ho Cha;
- Ukani, Lubna;
- Chepanoske, Cindy Lou;
- Yuejun Zhen;
- Sahasrabudhe, Sudhir;
- Olson, James;
- Kurschner, Cornelia;
- Ellerby, Lisa M.;
- Peltier, John M.;
- Botas, Juan
Publication type:
Article
FOXO3 targets are reprogrammed as Huntington's disease neural cells and striatal neurons face senescence with p16<sup>INK4a</sup> increase.
Published in:
Aging Cell, 2020, v. 19, n. 11, p. 1, doi. 10.1111/acel.13226
By:
- Voisin, Jessica;
- Farina, Francesca;
- Naphade, Swati;
- Fontaine, Morgane;
- Tshilenge, Kizito‐Tshitoko;
- Galicia Aguirre, Carlos;
- Lopez‐Ramirez, Alejandro;
- Dancourt, Julia;
- Ginisty, Aurélie;
- Sasidharan Nair, Satish;
- Lakshika Madushani, Kuruwitage;
- Zhang, Ningzhe;
- Lejeune, François‐Xavier;
- Verny, Marc;
- Campisi, Judith;
- Ellerby, Lisa M.;
- Neri, Christian
Publication type:
Article
Polyglutamine Disease Modeling: Epitope Based Screen for Homologous Recombination using CRISPR/Cas9 System.
Published in:
PLoS Currents, 2014, p. 369, doi. 10.1371/currents.hd.0242d2e7ad72225efa72f6964589369a
By:
- An, Mahru C.;
- O'Brien, Robert N.;
- Ningzhe Zhang;
- Patra, Biranchi N.;
- De La Cruz, Michael;
- Ray, Animesh;
- Ellerby, Lisa M.
Publication type:
Article
Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity.
Published in:
Genome Biology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s13059-021-02301-6
By:
- Sorek, Matan;
- Oweis, Walaa;
- Nissim-Rafinia, Malka;
- Maman, Moria;
- Simon, Shahar;
- Hession, Cynthia C.;
- Adiconis, Xian;
- Simmons, Sean K.;
- Sanjana, Neville E.;
- Shi, Xi;
- Lu, Congyi;
- Pan, Jen Q.;
- Xu, Xiaohong;
- Pouladi, Mahmoud A.;
- Ellerby, Lisa M.;
- Zhang, Feng;
- Levin, Joshua Z.;
- Meshorer, Eran
Publication type:
Article
Altered Expression of Matrix Metalloproteinases and Their Endogenous Inhibitors in a Human Isogenic Stem Cell Model of Huntington's Disease.
Published in:
Frontiers in Neuroscience, 2018, p. 1, doi. 10.3389/fnins.2017.00736
By:
- Naphade, Swati;
- Embusch, Alexander;
- Madushani, Kuruwitage Lakshika;
- Ring, Karen L.;
- Ellerby, Lisa M.
Publication type:
Article
Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation.
Published in:
eLife, 2021, p. 1, doi. 10.7554/eLife.65979
By:
- Cirnaru, Maria-Daniela;
- Sicheng Song;
- Tshilenge, Kizito-Tshitoko;
- Chuhyon Corwin;
- Mleczko, Justyna;
- Aguirre, Carlos Galicia;
- Benlhabib, Houda;
- Bendl, Jaroslav;
- Apontes, Pasha;
- Fullard, John;
- Creus-Muncunill, Jordi;
- Reyahi, Azadeh;
- Nik, Ali M.;
- Carlsson, Peter;
- Roussos, Panos;
- Mooney, Sean D.;
- Ellerby, Lisa M.;
- Ehrlich, Michelle E.
Publication type:
Article
Proteolytic cleavage of ataxin-7 promotes SCA7 retinal degeneration and neurological dysfunction.
Published in:
Human Molecular Genetics, 2015, v. 24, n. 14, p. 3908, doi. 10.1093/hmg/ddv121
By:
- Guyenet, Stephan J.;
- Mookerjee, Shona S.;
- Lin, Amy;
- Custer, Sara K.;
- Chen, Sylvia F.;
- Sopher, Bryce L.;
- La Spada, Albert R.;
- Ellerby, Lisa M.
Publication type:
Article
Correction to: N-Propargylglycine: a unique suicide inhibitor of proline dehydrogenase with anticancer activity and brain-enhancing mitohormesis properties.
Published in:
2021
By:
- Scott, Gary K.;
- Mahoney, Sophia;
- Scott, Madeleine;
- Loureiro, Ashley;
- Lopez-Ramirez, Alejandro;
- Tanner, John J.;
- Ellerby, Lisa M.;
- Benz, Christopher C.
Publication type:
Correction Notice
N-Propargylglycine: a unique suicide inhibitor of proline dehydrogenase with anticancer activity and brain-enhancing mitohormesis properties.
Published in:
Amino Acids, 2021, v. 53, n. 12, p. 1927, doi. 10.1007/s00726-021-03012-9
By:
- Scott, Gary K.;
- Mahoney, Sophia;
- Scott, Madeleine;
- Loureiro, Ashley;
- Lopez-Ramirez, Alejandro;
- Tanner, John J.;
- Ellerby, Lisa M.;
- Benz, Christopher C.
Publication type:
Article
Caspase-6 Activity in a BACHD Mouse Modulates Steady-State Levels of Mutant Huntingtin Protein But Is Not Necessary for Production of a 586 Amino Acid Proteolytic Fragment.
Published in:
Journal of Neuroscience, 2012, v. 32, n. 22, p. 7454, doi. 10.1523/JNEUROSCI.6379-11.2012
By:
- Gafni, Juliette;
- Papanikolaou, Theodora;
- DeGiacomo, Francesco;
- Holcomb, Jennifer;
- Sylvia Chen;
- Menalled, Liliana;
- Kudwa, Andrea;
- Fitzpatrick, Jon;
- Miller, Sam;
- Ramboz, Sylvie;
- Tuunanen, Pasi I.;
- Lehtimäki, Kimmo K.;
- Yang, X. William;
- Larry Park;
- Seung Kwak;
- Howland, David;
- Hyunsun Park;
- Ellerby, Lisa M.
Publication type:
Article
Posttranslational Modification of Ataxin-7 at Lysine 257 Prevents Autophagy-Mediated Turnover of an N-Terminal Caspase-7 Cleavage Fragment.
Published in:
Journal of Neuroscience, 2009, v. 29, n. 48, p. 15134, doi. 10.1523/JNEUROSCI.4720-09.2009
By:
- Mookerjee, Shona;
- Papanikolaou, Theodora;
- Guyenet, Stephan J.;
- Sampath, Vanitha;
- Lin, Amy;
- Vitelli, Cathy;
- DeGiacomo, Francesco;
- Sopher, Bryce L.;
- Chen, Sylvia F.;
- La Spada, Albert R.;
- Ellerby, Lisa M.
Publication type:
Article
Polyglutamine-Expanded Androgen Receptor Truncation Fragments Activate a Bax-Dependent Apoptotic Cascade Mediated by DP5/Hrk.
Published in:
Journal of Neuroscience, 2009, v. 29, n. 7, p. 1987, doi. 10.1523/JNEUROSCI.4072-08.2009
By:
- Young, Jessica E.;
- Garden, Gwenn A.;
- Martinez, Refugio A.;
- Tanaka, Fumiaki;
- Sandoval, C. Miguel;
- Smith, Annette C.;
- Sopher, Bryce L.;
- Lin, Amy;
- Fischbeck, Kenneth H.;
- Ellerby, Lisa M.;
- Morrison, Richard S.;
- Taylor, J. Paul;
- La Spada, Albert R.
Publication type:
Article
Mitochondrial-Dependent Ca<sup>2+</sup> Handling in Huntington's Disease Striatal Cells: Effect of Histone Deacetylase Inhibitors.
Published in:
Journal of Neuroscience, 2006, v. 26, n. 43, p. 11174, doi. 10.1523/JNEUROSCI.3004-06.2006
By:
- Oliveira, Jorge M. A.;
- Chen, Sylvia;
- Almeida, Sandra;
- Riley, Rebeccah;
- Gonçalves, Jorge;
- Oliveira, Catarina R.;
- Hayden, Michael R.;
- Nicholls, David G.;
- Ellerby, Lisa M.;
- Rego, A. Christina
Publication type:
Article
Striatal Cholinergic Dysregulation after Neonatal Decrease in X‐Linked Dystonia Parkinsonism‐Related TAF1 Isoforms.
Published in:
Movement Disorders, 2021, v. 36, n. 12, p. 2780, doi. 10.1002/mds.28750
By:
- Cirnaru, Maria‐Daniela;
- Creus‐Muncunill, Jordi;
- Nelson, Shareen;
- Lewis, Travis B.;
- Watson, Jaime;
- Ellerby, Lisa M.;
- Gonzalez‐Alegre, Pedro;
- Ehrlich, Michelle E.
Publication type:
Article
Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels.
Published in:
Autophagy, 2021, v. 17, n. 12, p. 4119, doi. 10.1080/15548627.2021.1904489
By:
- Bailus, Barbara J.;
- Scheeler, Stephen M.;
- Simons, Jesse;
- Sanchez, Maria A.;
- Tshilenge, Kizito-Tshitoko;
- Creus-Muncunill, Jordi;
- Naphade, Swati;
- Lopez-Ramirez, Alejandro;
- Zhang, Ningzhe;
- Lakshika Madushani, Kuruwitage;
- Moroz, Stanislav;
- Loureiro, Ashley;
- Schreiber, Katherine H.;
- Hausch, Felix;
- Kennedy, Brian K.;
- Ehrlich, Michelle E.;
- Ellerby, Lisa M.
Publication type:
Article
Autophagy.
Published in:
Autophagy, 2010, v. 6, n. 2, p. 312, doi. 10.4161/auto.6.2.11139
By:
- Duncan, Carlotta;
- Papanikolaou, Theodora;
- Ellerby, Lisa M.
Publication type:
Article