Works by Elfiky, Abdo A.

Results: 40

Understanding the association of cell-surface proteins (ACE2 and GRP78) facilitating pathogen recognition: a computational approach.

Published in:

Journal of Receptors & Signal Transduction, 2025, v. 45, n. 3, p. 182, doi. 10.1080/10799893.2025.2502383

By:

Elshemey, Wael M.;
Ibrahim, Ibrahim M.;
Elfiky, Abdo A.

Publication type:

Article

Acetylcholinesterase – glucose-regulated protein 78 binding site prediction, a hope to cure neurological disorders such as Alzheimer's disease.

Published in:

Journal of Receptors & Signal Transduction, 2024, v. 44, n. 3, p. 122, doi. 10.1080/10799893.2024.2426523

By:

Ali, Ahmed M.;
Mohamed, Ahmed A.;
Ibrahim, Ahmed N.;
Elfiky, Abdo A.

Publication type:

Article

Investigating the Structure–Activity Relationship of Laulimalides Marine Macrolides as Promising Inhibitors for SARS-CoV-2 Main Protease (Mpro).

Published in:

Journal of Computational Biophysics & Chemistry, 2025, v. 24, n. 4, p. 403, doi. 10.1142/S2737416524500637

By:

Elgohary, Alaa M.;
Elfiky, Abdo A.;
Pereira, Florbela;
El-Din, Mariam I. Gamal;
Tammam, Mohamed A.;
Aouidate, Adnane;
El-Demerdash, Amr

Publication type:

Article

Triple targeting of human IMPDH, SARS-CoV-2 RdRp, and Rhizopus oryzae RdRp: An in silico perspective.

Published in:

Journal of King Saud University - Science, 2023, v. 35, n. 10, p. N.PAG, doi. 10.1016/j.jksus.2023.102923

By:

Hassan, Abdel-moniem S.;
Elfiky, Abdo A.;
Elgohary, Alaa M.

Publication type:

Article

Tackling SARS‐CoV‐2: Deep Purpose Virtual Screening Identified Compounds to Target the Glycosylated Full‐Length GRP78.

Published in:

Advanced Theory & Simulations, 2024, v. 7, n. 10, p. 1, doi. 10.1002/adts.202400378

By:

Elshemey, Wael M.;
Ibrahim, Ibrahim M.;
Ezat, Ahmed A.;
Elgohary, Alaa M.;
Elfiky, Abdo A.;
Nassar, Aaya M.

Publication type:

Article

SARS-CoV-2 Delta Variant is Recognized Through GRP78 Host-Cell Surface Receptor, In Silico Perspective.

Published in:

International Journal of Peptide Research & Therapeutics, 2022, v. 28, n. 5, p. 1, doi. 10.1007/s10989-022-10450-w

By:

Elfiky, Abdo A.;
Ibrahim, Ibrahim M.;
Elgohary, Alaa M.

Publication type:

Article

Molecular Modeling Comparison of the Performance of NS5b Polymerase Inhibitor (PSI-7977) on Prevalent HCV Genotypes.

Published in:

Protein Journal, 2013, v. 32, n. 1, p. 75, doi. 10.1007/s10930-013-9462-9

By:

Elfiky, Abdo;
Elshemey, Wael;
Gawad, Wissam;
Desoky, Omar

Publication type:

Article

Correlation to Protein Conformation of Wide-Angle X-ray Scatter Parameters.

Published in:

Protein Journal, 2010, v. 29, n. 8, p. 545, doi. 10.1007/s10930-010-9291-z

By:

Elshemey, Wael M.;
Elfiky, Abdo A.;
Gawad, Wissam A.

Publication type:

Article

An insight into synthesis and antitumor activity of citrate and gallate stabilizing gold nanospheres.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-29821-4

By:

Fathy, Mohamed M.;
Elfiky, Abdo A.;
Bashandy, Yousef S.;
Hamdy, Mayar M.;
Elgharib, Ahmed M.;
Ibrahim, Ibrahim M.;
Kamal, Rana T.;
Mohamed, Ahmed S.;
Rashad, Anan M.;
Ahmed, Ola S.;
Elkaramany, Yomna;
Abdelaziz, Youssef S.;
Amin, Fatma G.;
Eid, Jehane I.

Publication type:

Article

Targeting SARS-CoV-2 endoribonuclease: a structure-based virtual screening supported by in vitro analysis.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-17573-6

By:

Ibrahim, Ibrahim M.;
Elfiky, Abdo A.;
Fathy, Mohamed M.;
Mahmoud, Sara H.;
ElHefnawi, Mahmoud

Publication type:

Article

SARS-CoV-2 Papain-like Protease as a Target for Anti-HCV and Anti-HIV Proteases: In silico Perspective.

Published in:

Systematic Reviews in Pharmacy, 2022, v. 13, n. 3, p. 242, doi. 10.31858/0975-8453.13.3.242-250

By:

Elfiky, Abdo A.

Publication type:

Article

SARS-CoV-2 Spike-Heat Shock Protein A5 (GRP78) Recognition may be Related to the Immersed Human Coronaviruses.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.577467

By:

Elfiky, Abdo A.

Publication type:

Article

SARS-CoV-2 spike behavior in situ: a Cryo-EM images for a better understanding of the COVID-19 pandemic.

Published in:

Signal Transduction & Targeted Therapy, 2020, v. 5, n. 1, p. N.PAG, doi. 10.1038/s41392-020-00365-7

By:

Ismail, Alaa M.;
Elfiky, Abdo A.

Publication type:

Article

Potential antiviral properties of antiplatelet agents against SARS-CoV-2 infection: an in silico perspective.

Published in:

Journal of Thrombosis & Thrombolysis, 2022, v. 53, n. 2, p. 273, doi. 10.1007/s11239-021-02558-5

By:

Abosheasha, Mohammed A.;
El-Gowily, Afnan H.;
Elfiky, Abdo A.

Publication type:

Article

Human papillomavirus E6: Host cell receptor, GRP78, binding site prediction.

Published in:

Journal of Medical Virology, 2020, v. 92, n. 12, p. 3759, doi. 10.1002/jmv.25737

By:

Elfiky, Abdo A.

Publication type:

Article

Novel guanosine derivatives against Zika virus polymerase in silico.

Published in:

Journal of Medical Virology, 2020, v. 92, n. 1, p. 11, doi. 10.1002/jmv.25573

By:

Elfiky, Abdo A.

Publication type:

Article

Molecular dynamics simulation revealed binding of nucleotide inhibitors to ZIKV polymerase over 444 nanoseconds.

Published in:

Journal of Medical Virology, 2018, v. 90, n. 1, p. 13, doi. 10.1002/jmv.24934

By:

Elfiky, Abdo A.;
Elshemey, Wael M.

Publication type:

Article

Quantitative structure-activity relationship and molecular docking revealed a potency of anti-hepatitis C virus drugs against human corona viruses.

Published in:

Journal of Medical Virology, 2017, v. 89, n. 6, p. 1040, doi. 10.1002/jmv.24736

By:

Elfiky, Abdo A.;
Mahdy, Samah M.;
Elshemey, Wael M.

Publication type:

Article

Zika viral polymerase inhibition using anti-HCV drugs both in market and under clinical trials.

Published in:

Journal of Medical Virology, 2016, v. 88, n. 12, p. 2044, doi. 10.1002/jmv.24678

By:

Elfiky, Abdo A.

Publication type:

Article

Chia seeds and coenzyme Q<sub>10</sub> alleviate iron overload induced hepatorenal toxicity in mice via iron chelation and oxidative stress modulation.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-47127-3

By:

Sadek, Shimaa A.;
Marzouk, Mohamed;
Mohamed, Hanan R. H.;
El-sallam, Bassant F. Abd;
Elfiky, Abdo A.;
Sayed, Amany A.

Publication type:

Article

Recognition of gluconeogenic enzymes; Icl1, Fbp1, and Mdh2 by Gid4 ligase: A molecular docking study.

Published in:

Journal of Molecular Recognition, 2020, v. 33, n. 5, p. 1, doi. 10.1002/jmr.2831

By:

Elfiky, Abdo A.;
Ismail, Alaa M.;
Elshemey, Wael M.

Publication type:

Article

Recognition of the gluconeogenic enzyme, Pck1, via the Gid4 E3 ligase: An in silico perspective.

Published in:

Journal of Molecular Recognition, 2020, v. 33, n. 3, p. N.PAG, doi. 10.1002/jmr.2821

By:

Ismail, Alaa M.;
Elfiky, Abdo A.;
Elshemey, Wael M.

Publication type:

Article

Nonhuman primates as valuable models for mpox drug and vaccine discovery.

Published in:

Expert Opinion on Drug Discovery, 2025, v. 20, n. 5, p. 575, doi. 10.1080/17460441.2025.2489473

By:

Rashwan, Mahmoud E.;
Amer, Mohamed A. S.;
Elshemey, Wael M.;
Elfiky, Abdo A.

Publication type:

Article

The discovery of novel antivirals for the treatment of mpox: is drug repurposing the answer?

Published in:

Expert Opinion on Drug Discovery, 2023, v. 18, n. 5, p. 551, doi. 10.1080/17460441.2023.2199980

By:

Ezat, Ahmed A.;
Abduljalil, Jameel M.;
Elghareib, Ahmed M.;
Samir, Ahmed;
Elfiky, Abdo A.

Publication type:

Article

The anti-HCV, Sofosbuvir, versus the anti-EBOV Remdesivir against SARS-CoV-2 RNA dependent RNA polymerase in silico.

Published in:

Molecular Diversity, 2022, v. 26, n. 1, p. 171, doi. 10.1007/s11030-020-10178-z

By:

Elfiky, Abdo A.;
Azzam, Eman B.;
Shafaa, Medhat W.

Publication type:

Article

Molecular dynamics simulations and MM-GBSA reveal a novel small molecule against Flu A RNA-dependent RNA polymerase.

Published in:

Journal of Biomolecular Structure & Dynamics, 2025, v. 43, n. 4, p. 1869, doi. 10.1080/07391102.2023.2293263

By:

Samir, Ahmed;
Elshemey, Wael M.;
Elfiky, Abdo A.

Publication type:

Article

Serine/threonine kinase of Mpox virus: computational modeling and structural analysis.

Published in:

Journal of Biomolecular Structure & Dynamics, 2024, v. 42, n. 22, p. 12434, doi. 10.1080/07391102.2023.2270680

By:

Abduljalil, Jameel M.;
Al-Madhagi, Haitham A.;
Elfiky, Abdo A.;
AlKhazindar, Maha M.

Publication type:

Article

Targeting of HPV E6 at the binding sites to the host-cell E6AP, p53, and the endoplasmic reticulum-resident chaperone, GRP78.

Published in:

Journal of Biomolecular Structure & Dynamics, 2024, v. 42, n. 22, p. 12385, doi. 10.1080/07391102.2023.2270067

By:

Elfiky, Abdo A.;
Saied, Hazem R.;
Ali, Maha A.

Publication type:

Article

A structural-based virtual screening and in vitro validation reveals novel effective inhibitors for SARS-CoV-2 helicase and endoribonuclease.

Published in:

Journal of Biomolecular Structure & Dynamics, 2024, v. 42, n. 17, p. 9145, doi. 10.1080/07391102.2023.2250479

By:

Ibrahim, Ibrahim M.;
Elfiky, Abdo A.;
Mahmoud, Sara H.;
ElHefnawi, Mahmoud

Publication type:

Article

In silico targeting of SARS-CoV-2 spike receptor-binding domain from different variants with chaga mushroom terpenoids.

Published in:

Journal of Biomolecular Structure & Dynamics, 2024, v. 42, n. 2, p. 1079, doi. 10.1080/07391102.2023.2199084

By:

Amin, Fatma G.;
Elfiky, Abdo A.;
Nassar, Aaya M.

Publication type:

Article

Can de-phosphorylation of serine-5 in the C-terminal domain of human polymerase II affect its interaction with the PA C-terminal domain of bat Flu A polymerase?

Published in:

Journal of Biomolecular Structure & Dynamics, 2024, v. 42, n. 1, p. 1, doi. 10.1080/07391102.2022.2152872

By:

Samir, Ahmed;
Elshemey, Wael;
Elfiky, Abdo

Publication type:

Article

In silico structural elucidation of Nipah virus L protein and targeting RNA-dependent RNA polymerase domain by nucleoside analogs.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 17, p. 8215, doi. 10.1080/07391102.2022.2130987

By:

Abduljalil, Jameel M.;
Elfiky, Abdo A.;
Sayed, El-Sayed T. A.;
AlKhazindar, Maha M.

Publication type:

Article

Anti-breast cancer drugs targeting cell-surface glucose-regulated protein 78: a drug repositioning in silico study.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 16, p. 7794, doi. 10.1080/07391102.2022.2125076

By:

Abu-Mahfouz, Alaa;
Ali, Maha;
Elfiky, Abdo

Publication type:

Article

Zika virus envelope – heat shock protein A5 (GRP78) binding site prediction.

Published in:

Journal of Biomolecular Structure & Dynamics, 2021, v. 39, n. 14, p. 5248, doi. 10.1080/07391102.2020.1784794

By:

Elfiky, Abdo A.;
Ibrahim, Ibrahim M.

Publication type:

Article

SARS-CoV-2 RNA dependent RNA polymerase (RdRp) targeting: an in silico perspective.

Published in:

Journal of Biomolecular Structure & Dynamics, 2021, v. 39, n. 9, p. 3204, doi. 10.1080/07391102.2020.1761882

By:

Elfiky, Abdo A.

Publication type:

Article

Natural products may interfere with SARS-CoV-2 attachment to the host cell.

Published in:

Journal of Biomolecular Structure & Dynamics, 2021, v. 39, n. 9, p. 3194, doi. 10.1080/07391102.2020.1761881

By:

Elfiky, Abdo A.

Publication type:

Article

Novel guanosine derivatives against MERS CoV polymerase: An in silico perspective.

Published in:

Journal of Biomolecular Structure & Dynamics, 2021, v. 39, n. 8, p. 2923, doi. 10.1080/07391102.2020.1758789

By:

Elfiky, Abdo A.;
Azzam, Eman B.

Publication type:

Article

Predicting the insecticide-driven mutations in a crop pest insect: Evidence for multiple polymorphisms of acetylcholinesterase gene with potential relevance for resistance to chemicals.

Published in:

Environmental Science & Pollution Research, 2023, v. 30, n. 7, p. 18937, doi. 10.1007/s11356-022-23309-w

By:

Renault, David;
Elfiky, Abdo;
Mohamed, Amr

Publication type:

Article

A Review of Human Coronaviruses' Receptors: The Host-Cell Targets for the Crown Bearing Viruses.

Published in:

Molecules, 2021, v. 26, n. 21, p. 6455, doi. 10.3390/molecules26216455

By:

Nassar, Aaya;
Ibrahim, Ibrahim M.;
Amin, Fatma G.;
Magdy, Merna;
Elgharib, Ahmed M.;
Azzam, Eman B.;
Nasser, Filopateer;
Yousry, Kirllos;
Shamkh, Israa M.;
Mahdy, Samah M.;
Elfiky, Abdo A.

Publication type:

Article

Clean Grinding Technique: A Facile Synthesis and In Silico Antiviral Activity of Hydrazones, Pyrazoles, and Pyrazines Bearing Thiazole Moiety against SARS-CoV-2 Main Protease (Mpro).

Published in:

Molecules, 2020, v. 25, n. 19, p. 4565, doi. 10.3390/molecules25194565

By:

Abu-Melha, Sraa;
Edrees, Mastoura M.;
Riyadh, Sayed M.;
Abdelaziz, Mohamad R.;
Elfiky, Abdo A.;
Gomha, Sobhi M.

Publication type:

Article