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Study of the mechanisms of crocetin‐induced differentiation and apoptosis in human acute promyelocytic leukemia cells.
- Published in:
- Journal of Cellular Biochemistry, 2019, v. 120, n. 2, p. 1943, doi. 10.1002/jcb.27489
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- Publication type:
- Article
Study of the mechanisms of crocetin‐induced differentiation and apoptosis in human acute promyelocytic leukemia cells.
- Published in:
- Journal of Cellular Biochemistry, 2019, v. 120, n. 2, p. 1943, doi. 10.1002/jcb.27489
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- Publication type:
- Article
SMN-deficient cells exhibit increased ribosomal DNA damage.
- Published in:
- Life Science Alliance, 2022, v. 5, n. 8, p. 1, doi. 10.26508/lsa.202101145
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- Publication type:
- Article
A role for Rad5 in ribonucleoside monophosphate (rNMP) tolerance.
- Published in:
- Life Science Alliance, 2021, v. 4, n. 10, p. 1, doi. 10.26508/lsa.202000966
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- Publication type:
- Article
The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates.
- Published in:
- 2006
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- Publication type:
- Letter
Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1.
- Published in:
- Nature, 2005, v. 434, n. 7029, p. 108, doi. 10.1038/nature03314
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- Publication type:
- Article
Expression of a pathogenic mutation of SOD1 sensitizes aprataxin-deficient cells and mice to oxidative stress and triggers hallmarks of premature ageing
- Published in:
- Human Molecular Genetics, 2015, v. 24, n. 3, p. 828, doi. 10.1093/hmg/ddu500
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- Publication type:
- Article
Perturbed autophagy and DNA repair converge to promote neurodegeneration in amyotrophic lateral sclerosis and dementia.
- Published in:
- 2018
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- Publication type:
- journal article
DNA Homeostasis and Senescence: Lessons from the Naked Mole Rat.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 11, p. 6011, doi. 10.3390/ijms22116011
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- Publication type:
- Article
A human 5′-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage.
- Published in:
- Nature, 2009, v. 461, n. 7264, p. 674, doi. 10.1038/nature08444
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- Publication type:
- Article
TDP1-dependent DNA single-strand break repair and neurodegeneration.
- Published in:
- Mutagenesis, 2006, v. 21, n. 4, p. 219, doi. 10.1093/mutage/gel024
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- Publication type:
- Article
High Glucose Increases DNA Damage and Elevates the Expression of Multiple DDR Genes.
- Published in:
- Genes, 2023, v. 14, n. 1, p. 144, doi. 10.3390/genes14010144
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- Publication type:
- Article
TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function.
- Published in:
- Nature Genetics, 2014, v. 46, n. 5, p. 516, doi. 10.1038/ng.2929
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- Publication type:
- Article
CORM-3 induces DNA damage through Ru(II) binding to DNA.
- Published in:
- Biochemical Journal, 2022, v. 479, n. 13, p. 1429, doi. 10.1042/BCJ20220254
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- Publication type:
- Article
USP11 controls R-loops by regulating senataxin proteostasis.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25459-w
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- Publication type:
- Article
Hypoxia-induced SETX links replication stress with the unfolded protein response.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24066-z
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- Publication type:
- Article
To live or to die: a matter of processing damaged DNA termini in neurons.
- Published in:
- EMBO Molecular Medicine, 2011, v. 3, n. 2, p. 78, doi. 10.1002/emmm.201000114
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- Publication type:
- Article
ATM Deficiency Results in Accumulation of DNA-Topoisomerase I Covalent Intermediates in Neural Cells.
- Published in:
- PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0058239
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- Publication type:
- Article
The DNA repair kinase ATM regulates CD13 expression and cell migration.
- Published in:
- Frontiers in Cell & Developmental Biology, 2024, p. 1, doi. 10.3389/fcell.2024.1359105
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- Publication type:
- Article
Isoeugenol is a selective potentiator of camptothecin cytotoxicity in vertebrate cells lacking TDP1.
- Published in:
- Scientific Reports, 2016, p. 26626, doi. 10.1038/srep26626
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- Publication type:
- Article
Editorial: Genomic Instability and Neurodegeneration.
- Published in:
- 2022
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- Publication type:
- Editorial
Gold nanoparticles – an optical biosensor for RNA quantification for cancer and neurologic disorders diagnosis.
- Published in:
- International Journal of Nanomedicine, 2018, v. 13, p. 8137, doi. 10.2147/IJN.S181732
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- Publication type:
- Article
Defective repair of topoisomerase I induced chromosomal damage in Huntington’s disease.
- Published in:
- Cellular & Molecular Life Sciences, 2022, v. 79, n. 3, p. 1, doi. 10.1007/s00018-022-04204-6
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- Publication type:
- Article
DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity.
- Published in:
- Cellular & Molecular Life Sciences, 2021, v. 78, n. 15, p. 5707, doi. 10.1007/s00018-021-03872-0
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- Publication type:
- Article
TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo.
- Published in:
- EMBO Journal, 2007, v. 26, n. 22, p. 4720, doi. 10.1038/sj.emboj.7601869
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- Publication type:
- Article
Integrative microRNA and gene expression analysis identifies new epigenetically regulated microRNAs mediating taxane resistance in ovarian cancer.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-78596-5
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- Publication type:
- Article
Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan.
- Published in:
- Nucleic Acids Research, 2017, v. 45, n. 3, p. 1159, doi. 10.1093/nar/gkw1026
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- Publication type:
- Article
TDP1 deficiency sensitizes human cells to base damage via distinct topoisomerase I and PARP mechanisms with potential applications for cancer therapy.
- Published in:
- Nucleic Acids Research, 2014, v. 42, n. 5, p. 3089, doi. 10.1093/nar/gkt1260
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- Publication type:
- Article
TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1.
- Published in:
- Nucleic Acids Research, 2012, v. 40, n. 17, p. 8371, doi. 10.1093/nar/gks622
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- Publication type:
- Article
A requirement for PARP‐1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage.
- Published in:
- Nucleic Acids Research, 2003, v. 31, n. 19, p. 5526
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- Publication type:
- Article
TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15000-w
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- Publication type:
- Article
Typhoid toxin exhausts the RPA response to DNA replication stress driving senescence and Salmonella infection.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12064-1
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- Publication type:
- Article
High Temperature Drives Topoisomerase Mediated Chromosomal Break Repair Pathway Choice.
- Published in:
- Cancers, 2021, v. 13, n. 10, p. 2315, doi. 10.3390/cancers13102315
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- Publication type:
- Article
Identification and Validation of ERK5 as a DNA Damage Modulating Drug Target in Glioblastoma.
- Published in:
- Cancers, 2021, v. 13, n. 5, p. 944, doi. 10.3390/cancers13050944
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- Publication type:
- Article
Topoisomerase-mediated chromosomal break repair: an emerging player in many games.
- Published in:
- Nature Reviews Cancer, 2015, v. 15, n. 3, p. 137, doi. 10.1038/nrc3892
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- Publication type:
- Article
The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1.
- Published in:
- Nature Neuroscience, 2009, v. 12, n. 8, p. 973, doi. 10.1038/nn.2375
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- Publication type:
- Article
Recent advances in stem cells therapy: A focus on cancer, Parkinson's and Alzheimer's.
- Published in:
- Journal of Genetic Engineering & Biotechnology, 2018, v. 16, n. 2, p. 427, doi. 10.1016/j.jgeb.2018.09.002
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- Publication type:
- Article