Works by El-Demerdash, Ebtehal

Results: 50

Forskolin, a hedgehog signalling inhibitor, attenuates carbon tetrachloride-induced liver fibrosis in rats.

Published in:

2016

By:

El ‐ Agroudy, Nermeen N;
El ‐ Naga, Reem N;
El ‐ Razeq, Rania Abd;
El ‐ Demerdash, Ebtehal;
El-Agroudy, Nermeen N;
El-Naga, Reem N;
El-Razeq, Rania Abd;
El-Demerdash, Ebtehal

Publication type:

journal article

Can vildagliptin protect against radiation-induced premature ovarian failure? Insights into the AMPK and AKT signaling pathways.

Published in:

BMC Pharmacology & Toxicology, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s40360-025-00903-5

By:

Mahgoub, Nada A.;
El-Sherbiny, Doaa A.;
El-Demerdash, Ebtehal

Publication type:

Article

Effect of renin angiotensin blockers on angiotensin converting enzyme 2 level in cardiovascular patients.

Published in:

BMC Pharmacology & Toxicology, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s40360-023-00667-w

By:

Farid fahmy, Sarah;
El Derany, Marwa Omar;
Khorshid, Hazem;
Saleh, Ayman;
El-Demerdash, Ebtehal

Publication type:

Article

Prenatal modulation of NADPH-oxidase reverses the deranged GABA switch and rescues behavioral deficits in valproate ASD rat model.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1571008

By:

Yasseen, Basma A.;
Abdelkhalek, Hadeer;
Gohar, Sara;
Hatem, Yasmin;
El-Sayed, Hajar;
Elkhodiry, Aya A.;
Galal, Aya;
Samir, Aya;
Al-Shehaby, Nouran;
Elbenhawi, Malak W.;
Hamdy, Rehab;
Prince, Christine S.;
Kamel, Azza G.;
Badawy, Mohamed A.;
Soliman, Ghada F.;
ElMorsy, Soha Aly;
Gamal El-Din, Tamer M.;
El-Demerdash, Ebtehal;
Ali, Sameh S.;
Abdel-Rahman, Engy A.

Publication type:

Article

Obestatin can potentially differentiate Wharton’s jelly mesenchymal stem cells into insulin-producing cells.

Published in:

Cell & Tissue Research, 2018, v. 372, n. 1, p. 91, doi. 10.1007/s00441-017-2725-6

By:

El-Asfar, Rana K.;
Kamal, Mohamed M.;
Abd EL-Razek, Rania S.;
EL-Demerdash, Ebtehal;
El-Mesallamy, Hala O.

Publication type:

Article

Protective Effects of the Angiotensin II Receptor Blocker Losartan on Cisplatin-Induced Kidney Injury.

Published in:

Chemotherapy (0009-3157), 2009, v. 55, n. 6, p. 399, doi. 10.1159/000262453

By:

Saleh, Samira;
Ain-Shoka, Afaf A.;
El-Demerdash, Ebtehal;
Khalef, Marwa M.

Publication type:

Article

Selective A3 adenosine receptor agonist protects against doxorubicin-induced cardiotoxicity.

Published in:

2016

By:

Galal, Aya;
El-Bakly, Wesam;
Al Haleem, Ekram;
El-Demerdash, Ebtehal;
El-Bakly, Wesam M;
Al Haleem, Ekram Nemr Abd

Publication type:

journal article

2-Methoxyestradiol reverses doxorubicin resistance in human breast tumor xenograft.

Published in:

Cancer Chemotherapy & Pharmacology, 2008, v. 62, n. 5, p. 893, doi. 10.1007/s00280-008-0679-9

By:

Azab, Samar S.;
Salama, Salama A.;
Hassan, Memy H.;
Khalifa, Amani E.;
El-Demerdash, Ebtehal;
Fouad, Hala;
Al-Hendy, Ayman;
Abdel-Naim, Ashraf B.

Publication type:

Article

New aspects in probucol cardioprotection against doxorubicin-induced cardiotoxicity.

Published in:

Cancer Chemotherapy & Pharmacology, 2003, v. 52, n. 5, p. 411, doi. 10.1007/s00280-003-0676-y

By:

El-Demerdash, Ebtehal;
Ali, Azza A.;
Sayed-Ahmed, Mohamed M.;
Osman, Abdel-Moneim M.

Publication type:

Article

Metabolic/hypoxial axis predicts tamoxifen resistance in breast cancer.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-19977-w

By:

Azzam, Hany N.;
El-Derany, Marwa O.;
Wahdan, Sara A.;
Faheim, Reham M.;
Helal, Gouda K.;
El-Demerdash, Ebtehal

Publication type:

Article

Metabolic/hypoxial axis predicts tamoxifen resistance in breast cancer.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-19977-w

By:

Azzam, Hany N.;
El-Derany, Marwa O.;
Wahdan, Sara A.;
Faheim, Reham M.;
Helal, Gouda K.;
El-Demerdash, Ebtehal

Publication type:

Article

Molecular mechanisms underlying cyclophosphamide-induced cognitive impairment and strategies for neuroprotection in preclinical models.

Published in:

Molecular & Cellular Biochemistry, 2024, v. 479, n. 8, p. 1873, doi. 10.1007/s11010-023-04805-0

By:

Ibrahim, Kamilia M.;
Darwish, Samar F.;
Mantawy, Eman M.;
El-demerdash, Ebtehal

Publication type:

Article

Effect of phylloquinone on indomethacin‐induced gastric ulceration in rats: Role of SIRT‐1.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2023, v. 50, n. 5, p. 369, doi. 10.1111/1440-1681.13752

By:

Hamza, Sara E.;
Wahdan, Sara A.;
El‐Demerdash, Ebtehal

Publication type:

Article

Thymoquinone attenuates isoproterenol‐induced myocardial infarction by inhibiting cytochrome C and matrix metalloproteinase‐9 expression.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2022, v. 49, n. 3, p. 391, doi. 10.1111/1440-1681.13614

By:

Medhet, Marwa;
El‐Bakly, Wesam M.;
Badr, Amira M.;
Awad, Azza;
El‐Demerdash, Ebtehal

Publication type:

Article

Rosuvastatin and low‐dose carvedilol combination protects against isoprenaline‐induced myocardial infarction in rats: Role of PI3K/Akt/Nrf2/HO‐1 signalling.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2021, v. 48, n. 10, p. 1358, doi. 10.1111/1440-1681.13535

By:

Baraka, Sarah A.;
Tolba, Mai F.;
Elsherbini, Doaa A.;
El‐Naga, Reem N.;
Awad, Azza S.;
El‐Demerdash, Ebtehal

Publication type:

Article

Deferoxamine alleviates liver fibrosis induced by CCl<sub>4</sub> in rats.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2016, v. 43, n. 8, p. 760, doi. 10.1111/1440-1681.12591

By:

Mohammed, Aya;
Abd Al Haleem, Ekram N;
El ‐ Bakly, Wesam M;
El ‐ Demerdash, Ebtehal

Publication type:

Article

INHIBITION OF THE RENIN–ANGIOTENSIN SYSTEM ATTENUATES THE DEVELOPMENT OF LIVER FIBROSIS AND OXIDATIVE STRESS IN RATS.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2008, v. 35, n. 2, p. 159, doi. 10.1111/j.1440-1681.2007.04797.x

By:

El-Demerdash, Ebtehal;
Salam, Omar M Abdel;
El-Batran, Seham A;
Abdallah, Heba MI;
Shaffie, Nermeen M

Publication type:

Article

Effect of taurine supplementation on hyperhomocysteinemia and markers of oxidative stress in high fructose diet induced insulin resistance.

Published in:

Diabetology & Metabolic Syndrome, 2010, v. 2, n. 1, p. 1, doi. 10.1186/1758-5996-2-46

By:

El Mesallamy, Hala O.;
El-Demerdash, Ebtehal;
Hammad, Lamiaa N.;
El Magdoub, Hekmat M.

Publication type:

Article

2-Methoxyestradiol and multidrug resistance: can 2-methoxyestradiol chemosensitize resistant breast cancer cells?

Published in:

Breast Cancer Research & Treatment, 2009, v. 113, n. 1, p. 9, doi. 10.1007/s10549-008-9898-3

By:

Azab, Samar;
Salama, Salama;
Abdel-Naim, Ashraf;
Khalifa, Amani;
El-Demerdash, Ebtehal;
Al-Hendy, Ayman

Publication type:

Article

Effects of aged garlic and ginkgo biloba extracts on the pharmacokinetics of sofosbuvir in rats.

Published in:

Biopharmaceutics & Drug Disposition, 2022, v. 43, n. 4, p. 152, doi. 10.1002/bdd.2326

By:

Wasef, Abanoub K.;
Wahdan, Sara A.;
Saeed, Noha M.;
El‐Demerdash, Ebtehal

Publication type:

Article

Telmisartan ameliorates carbon tetrachloride-induced acute hepatotoxicity in rats.

Published in:

Environmental Toxicology, 2017, v. 32, n. 2, p. 359, doi. 10.1002/tox.22240

By:

Atawia, Reem T.;
Esmat, Ahmed;
Elsherbiny, Doaa A.;
El‐Demerdash, Ebtehal

Publication type:

Article

Captopril attenuates oxidative stress and neuroinflammation implicated in cisplatin-induced cognitive deficits in rats.

Published in:

Psychopharmacology, 2025, v. 242, n. 3, p. 563, doi. 10.1007/s00213-024-06706-6

By:

Mostafa, Fatma;
Mantawy, Eman M.;
Said, Riham S.;
Azab, Samar S.;
El-Demerdash, Ebtehal

Publication type:

Article

Biochanin A Protects against Acute Carbon Tetrachloride-Induced Hepatotoxicity in Rats.

Published in:

Bioscience, Biotechnology & Biochemistry, 2013, v. 77, n. 5, p. 909, doi. 10.1271/bbb.120675

By:

BREIKAA, Randa M.;
ALGANDABY, Mardi M.;
EL-DEMERDASH, Ebtehal;
ABDEL-NAIM, Ashraf B.

Publication type:

Article

Cytotoxic Effects of 2-Methoxyestradiol in the Hepatocellular Carcinoma Cell Line HepG2.

Published in:

Pharmacology, 2009, v. 84, n. 1, p. 9, doi. 10.1159/000221062

By:

El Naga, Reem N. Abou;
El-Demerdash, Ebtehal;
Youssef, Samar S.;
Abdel-Naim, Ashraf B.;
El-Merzabani, Mahmoud

Publication type:

Article

Naringin treatment improved main clozapine‐induced adverse effects in rats; emphasis on weight gain, metabolic abnormalities, and agranulocytosis.

Published in:

Drug Development Research, 2021, v. 82, n. 7, p. 980, doi. 10.1002/ddr.21800

By:

George, Mina Y.;
Menze, Esther T.;
Esmat, Ahmed;
Tadros, Mariane G.;
El‐Demerdash, Ebtehal

Publication type:

Article

Piceatannol ameliorates behavioural, biochemical and histological aspects in cisplatin‐induced peripheral neuropathy in rats.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2021, v. 129, n. 6, p. 486, doi. 10.1111/bcpt.13643

By:

Wahdan, Sara A.;
Elsherbiny, Doaa A.;
Azab, Samar S.;
El‐Demerdash, Ebtehal

Publication type:

Article

The natural flavonoid galangin ameliorates dextran sulphate sodium–induced ulcerative colitis in mice: Effect on Toll‐like receptor 4, inflammation and oxidative stress.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2020, v. 127, n. 1, p. 10, doi. 10.1111/bcpt.13388

By:

Gerges, Samar H.;
Tolba, Mai F.;
Elsherbiny, Doaa A.;
El‐Demerdash, Ebtehal

Publication type:

Article

Retraction Note: Piceatannol protects against cisplatin nephrotoxicity via activation of Nrf2/HO-1 pathway and hindering NF-κB inflammatory cascade.

Published in:

2023

By:

Wahdan, Sara A.;
Azab, Samar S.;
Elsherbiny, Doaa A.;
El-Demerdash, Ebtehal

Publication type:

Correction Notice

Correction to: Protection from doxorubicin-induced nephrotoxicity by clindamycin: novel antioxidant, anti-inflammatory and anti-apoptotic roles.

Published in:

2020

By:

Ibrahim, Kamilia M.;
Mantawy, Eman M.;
Elanany, Mona M.;
Abdelgawad, Hend S.;
Khalifa, Nuha M.;
Hussien, Rada H.;
El-Agroudy, Nermeen N.;
El-demerdash, Ebtehal

Publication type:

Correction Notice

Protection from doxorubicin-induced nephrotoxicity by clindamycin: novel antioxidant, anti-inflammatory and anti-apoptotic roles.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2020, v. 393, n. 4, p. 739, doi. 10.1007/s00210-019-01782-4

By:

Ibrahim, Kamilia M.;
Mantawy, Eman M.;
Elanany, Mona M.;
Abdelgawad, Hend S.;
Khalifa, Nuha M.;
Hussien, Rada H.;
El-Agroudy, Nermeen N.;
El-demerdash, Ebtehal

Publication type:

Article

Piceatannol protects against cisplatin nephrotoxicity via activation of Nrf2/HO-1 pathway and hindering NF-κB inflammatory cascade.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2019, v. 392, n. 11, p. 1331, doi. 10.1007/s00210-019-01673-8

By:

Wahdan, Sara A.;
Azab, Samar S.;
Elsherbiny, Doaa A.;
El-Demerdash, Ebtehal

Publication type:

Article

Mechanistic perspective of protective effects of resveratrol against cisplatin-induced ovarian injury in rats: emphasis on anti-inflammatory and anti-apoptotic effects.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2019, v. 392, n. 10, p. 1225, doi. 10.1007/s00210-019-01662-x

By:

Said, Riham S.;
Mantawy, Eman M.;
El-Demerdash, Ebtehal

Publication type:

Article

Effect of carvedilol on pharmacokinetics of sofosbuvir and its metabolite GS-331007: role of P-glycoprotein.

Published in:

Journal of Pharmacy & Pharmacology, 2024, v. 76, n. 8, p. 1051, doi. 10.1093/jpp/rgae070

By:

Fahmy, Salma N;
Khedr, Lobna H;
Wahdan, Sara A;
Menze, Esther T;
Azab, Samar S;
El-Demerdash, Ebtehal

Publication type:

Article

Eugenol modulates insulin sensitivity by upregulating insulin receptor substrate-2 in non-alcoholic fatty liver disease in rats.

Published in:

Journal of Pharmacy & Pharmacology, 2021, v. 73, n. 6, p. 846, doi. 10.1093/jpp/rgab032

By:

Fawzy, Mariam H.;
Saeed, Noha M.;
El-Sherbiny, Doaa A.;
El-Demerdash, Ebtehal

Publication type:

Article

Effect of low-protein diet on anthracycline pharmacokinetics and cardiotoxicity.

Published in:

Journal of Pharmacy & Pharmacology, 2012, v. 64, n. 3, p. 344, doi. 10.1111/j.2042-7158.2011.01413.x

By:

El-Demerdash, Ebtehal;
Ali, Azza A.;
El-Taher, Dalia E.M.;
Hamada, Farid M.A.

Publication type:

Article

Rubus sanctusprotects against carbon tetrachloride-induced toxicity in rat isolated hepatocytes: isolation and characterization of its galloylated flavonoids.

Published in:

Journal of Pharmacy & Pharmacology, 2009, v. 61, n. 11, p. 1511, doi. 10.1211/jpp/61.11.0011

By:

Amira M. Badr;
Ebtehal El-Demerdash;
Amani E. Khalifa;
Asser I. Ghoneim;
Nahla A. Ayoub;
Ashraf B. Abdel-Naim

Publication type:

Article

Phytoestrogen genistein hinders ovarian oxidative damage and apoptotic cell death-induced by ionizing radiation: co-operative role of ER-β, TGF-β, and FOXL-2.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-70309-2

By:

Haddad, Yasmin Hamdy;
Said, Riham S.;
Kamel, Rehab;
Morsy, Engy M. El;
El-Demerdash, Ebtehal

Publication type:

Article

Growth Hormone Ameliorates the Radiotherapy-Induced Ovarian Follicular Loss in Rats: Impact on Oxidative Stress, Apoptosis and IGF-1/IGF-1R Axis.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0140055

By:

Mahran, Yasmen F.;
El-Demerdash, Ebtehal;
Nada, Ahmed S.;
El-Naga, Reem N.;
Ali, Azza A.;
Abdel-Naim, Ashraf B.

Publication type:

Article

Targeting TNF-α and NF-κB Activation by Bee Venom: Role in Suppressing Adjuvant Induced Arthritis and Methotrexate Hepatotoxicity in Rats.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0079284

By:

Darwish, Samar F.;
El-Bakly, Wesam M.;
Arafa, Hossam M.;
El-Demerdash, Ebtehal

Publication type:

Article

Multimechanistic Antifibrotic Effect of Biochanin A in Rats: Implications of Proinflammatory and Profibrogenic Mediators.

Published in:

PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0069276

By:

Breikaa, Randa M.;
Algandaby, Mardi M.;
El-Demerdash, Ebtehal;
Abdel-Naim, Ashraf B.

Publication type:

Article

Sodium Selenite Improves Folliculogenesis in Radiation-Induced Ovarian Failure: A Mechanistic Approach.

Published in:

PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0050928

By:

Said, Riham S.;
Nada, Ahmed S.;
El-Demerdash, Ebtehal

Publication type:

Article

Bone Marrow Transplantation Restores Follicular Maturation and Steroid Hormones Production in a Mouse Model for Primary Ovarian Failure.

Published in:

PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032462

By:

Ghadami, Mohsen;
El-Demerdash, Ebtehal;
Zhang, Dong;
Salama, Salama A.;
Binhazim, Awadh A.;
Archibong, Anthony E.;
Chen, Xinlei;
Ballard, Billy R.;
Sairam, M. Ram;
Al-Hendy, Ayman

Publication type:

Article

The potential antifibrotic impact of apocynin and alpha-lipoic acid in concanavalin A-induced liver fibrosis in rats: Role of NADPH oxidases 1 and 4.

Published in:

Drug Discoveries & Therapeutics, 2018, v. 12, n. 2, p. 58, doi. 10.5582/ddt.2017.01065

By:

Fayed, Mostafa R.;
El-Naga, Reem N.;
Akool, El-Sayed;
El-Demerdash, Ebtehal

Publication type:

Article

A comparative study of protective mechanisms of glycine and L-arginine against cisplatin-induced nephrotoxicity in rat renal cortical slices.

Published in:

Drug Discoveries & Therapeutics, 2011, v. 5, n. 1, p. 32, doi. 10.5582/ddt.v5.1.32

By:

Mahran, Yasmen Y. F. K.;
Khalifa, Amani E.;
El-Demerdash, Ebtehal

Publication type:

Article

The potential therapeutic effect of nitric oxide modulators in experimentally-induced gastric ulcers.

Published in:

Drug Discoveries & Therapeutics, 2010, v. 4, n. 4, p. 276

By:

El-Demerdash, Ebtehal;
El-Mesallamy, Hala O.;
Abu-Zaid, Noha M.;
Gad, Mohamed Z.

Publication type:

Article

Antifibrotic Mechanism of Pinocembrin: Impact on Oxidative Stress, Inflammation and TGF-β/Smad Inhibition in Rats.

Published in:

Annals of Hepatology: Official Journal of the Mexican Association of Hepatology, 2018, v. 17, n. 2, p. 307, doi. 10.5604/01.3001.0010.8662

By:

Said, Marwa M.;
Azab, Samar S.;
Saeed, Noha M.;
El-Demerdash, Ebtehal

Publication type:

Article

Modulation of Imatinib Cytotoxicity by Selenite in HCT116 Colorectal Cancer Cells.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2015, v. 116, n. 1, p. 37, doi. 10.1111/bcpt.12281

By:

Abdel‐Aziz, Amal Kamal;
Azab, Samar Saad Eldeen;
Youssef, Samar Samir;
El‐Sayed, Abeer Mostafa;
El‐Demerdash, Ebtehal;
Shouman, Samia

Publication type:

Article

Protective Effects of L-Arginine against Cisplatin-Induced Renal Oxidative Stress and Toxicity: Role of Nitric Oxide.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2005, v. 97, n. 2, p. 91, doi. 10.1111/j.1742-7843.2005.pto_114.x

By:

Saleh, Samira;
El-Demerdash, Ebtehal

Publication type:

Article

Indole-3- carbinol enhances sorafenib cytotoxicity in hepatocellular carcinoma cells: A mechanistic study.

Published in:

Scientific Reports, 2016, p. 32733, doi. 10.1038/srep32733

By:

Abdelmageed, Mai M.;
El-Naga, Reem N.;
El-Demerdash, Ebtehal;
Elmazar, Mohamed M.

Publication type:

Article

The role of mitochondrial/metabolic axis in development of tamoxifen resistance in breast cancer.

Published in:

Human Cell, 2023, v. 36, n. 6, p. 1877, doi. 10.1007/s13577-023-00977-5

By:

Azzam, Hany N.;
El-Derany, Marwa O.;
Wahdan, Sara A.;
Faheim, Reham M.;
Helal, Gouda K.;
El-Demerdash, Ebtehal

Publication type:

Article