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The current state of molecular testing in the treatment of patients with solid tumors, 2019.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Correction: Anti-tumor effects of ONC201 in combination with VEGF-inhibitors significantly impacts colorectal cancer growth and survival in vivo through complementary non-overlapping mechanisms.
- Published in:
- 2024
- By:
- Publication type:
- Correction Notice
Expression of Immuno-Oncologic Biomarkers Is Enriched in Colorectal Cancers and Other Solid Tumors Harboring the A59T Variant of KRAS.
- Published in:
- Cells (2073-4409), 2021, v. 10, n. 6, p. 1275, doi. 10.3390/cells10061275
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- Publication type:
- Article
Endoplasmic reticulum calcium pool depletion-induced apoptosis is coupled with activation of the death receptor 5 pathway.
- Published in:
- Oncogene, 2002, v. 21, n. 17, p. 2623, doi. 10.1038/sj.onc.1205345
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- Publication type:
- Article
Tissue specific expression of p53 target genes suggests a key role for KILLER/DR5 in p53-dependent apoptosis in vivo.
- Published in:
- Oncogene, 2001, v. 20, n. 34, p. 4601, doi. 10.1038/sj.onc.1204484
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- Publication type:
- Article
Induction of the TRAIL receptor KILLER/DR5 in p53-dependent apoptosis but not growth arrest.
- Published in:
- Oncogene, 1999, v. 18, n. 47, p. 6411, doi. 10.1038/sj.onc.1203025
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- Publication type:
- Article
BRCA1 signals ARF-dependent stabilization and coactivation of p53.
- Published in:
- Oncogene, 1999, v. 18, n. 47, p. 6605, doi. 10.1038/sj.onc.1203284
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- Publication type:
- Article
The antiapoptotic decoy receptor TRID/TRAIL-R3 is a p53-regulated DNA damage-inducible gene that is overexpressed in primary tumors of the gastrointestinal tract.
- Published in:
- Oncogene, 1999, v. 18, n. 28, p. 4153, doi. 10.1038/sj.onc.1202763
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- Publication type:
- Article
Mechanisms of apoptosis induced by the synthetic retinoid CD437 in human non-small cell lung carcinoma cells.
- Published in:
- Oncogene, 1999, v. 18, n. 14, p. 2357, doi. 10.1038/sj.onc.1202543
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- Publication type:
- Article
Potential role for Cathepsin D in p53-dependent tumor suppression and chemosensitivity.
- Published in:
- Oncogene, 1998, v. 16, n. 17, p. 2177, doi. 10.1038/sj.onc.1201755
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- Publication type:
- Article
BRCA1 physically associates with p53 and stimulates its transcriptional activity.
- Published in:
- Oncogene, 1998, v. 16, n. 13, p. 1713, doi. 10.1038/sj.onc.1201932
- By:
- Publication type:
- Article
First-in-Human Phase 1b Trial of Quinacrine Plus Capecitabine in Patients With Refractory Metastatic Colorectal Cancer.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Personalized Dosing via Pharmacokinetic Monitoring of 5-Fluorouracil Might Reduce Toxicity in Early- or Late-Stage Colorectal Cancer Patients Treated With Infusional 5-Fluorouracil-Based Chemotherapy Regimens.
- Published in:
- Clinical Colorectal Cancer, 2014, v. 13, n. 2, p. 119, doi. 10.1016/j.clcc.2013.11.001
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- Publication type:
- Article
Corrigendum: Clinical Utilization Pattern of Liquid Biopsies (LB) to Detect Actionable Driver Mutations, Guide Treatment Decisions and Monitor Disease Burden During Treatment of 33 Metastatic Colorectal Cancer (mCRC) Patients (pts) at a Fox Chase Cancer Center GI Oncology Subspecialty Clinic
- Published in:
- 2021
- By:
- Publication type:
- Correction Notice
Challenges in Diversity, Equity, and Inclusion in Research and Clinical Oncology.
- Published in:
- Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2021.642112
- By:
- Publication type:
- Article
Frequent hypermethylation of the 5′ CpG island of the mitotic stress checkpoint gene Chfr in colorectal and non-small cell lung cancer.
- Published in:
- Carcinogenesis, 2003, v. 24, n. 1, p. 47, doi. 10.1093/carcin/24.1.47
- By:
- Publication type:
- Article
Anti-tumor effects of ONC201 in combination with VEGF-inhibitors significantly impacts colorectal cancer growth and survival in vivo through complementary non-overlapping mechanisms.
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2018, v. 37, p. 1, doi. 10.1186/s13046-018-0671-0
- By:
- Publication type:
- Article
Therapeutic targeting of TRAIL death receptors.
- Published in:
- Biochemical Society Transactions, 2023, v. 51, n. 1, p. 57, doi. 10.1042/BST20220098
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- Publication type:
- Article
Multispectral Fluorescence Imaging.
- Published in:
- Journal of Nuclear Medicine, 2009, v. 50, n. 10, p. 1563, doi. 10.2967/jnumed.109.063925
- By:
- Publication type:
- Article
GSK-3 Inhibitor Elraglusib Enhances Tumor-Infiltrating Immune Cell Activation in Tumor Biopsies and Synergizes with Anti-PD-L1 in a Murine Model of Colorectal Cancer.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 13, p. 10870, doi. 10.3390/ijms241310870
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- Publication type:
- Article
Advances in Liquid Biopsy Technology and Implications for Pancreatic Cancer.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 4, p. 4238, doi. 10.3390/ijms24044238
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- Publication type:
- Article
Differential p53-Mediated Cellular Responses to DNA-Damaging Therapeutic Agents.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 21, p. 11828, doi. 10.3390/ijms222111828
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- Publication type:
- Article
PBRM1 mutations might render a subtype of biliary tract cancers sensitive to drugs targeting the DNA damage repair system.
- Published in:
- NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00409-5
- By:
- Publication type:
- Article
A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutatedp53.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.70429
- By:
- Publication type:
- Article
Cytokine ranking via mutual information algorithm correlates cytokine profiles with presenting disease severity in patients infected with SARS-CoV-2.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.64958
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- Publication type:
- Article
Dopamine pre-treatment impairs the anti-cancer effect of integrated stress response- and TRAIL pathway-inducing ONC201, ONC206 and ONC212 imipridones in pancreatic, colorectal cancer but not DMG cells.
- Published in:
- American Journal of Cancer Research, 2024, v. 14, n. 5, p. 2453, doi. 10.62347/ZOTV8006
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- Publication type:
- Article
TRAIL and apoptosis induction by TNF-family death receptors.
- Published in:
- Oncogene, 2003, v. 22, n. 53, p. 8628, doi. 10.1038/sj.onc.1207232
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- Publication type:
- Article
Efficient growth inhibition of HPV 16 E6-expressing cells by an adenovirus-expressing p53 homologue p73ß.
- Published in:
- Oncogene, 2003, v. 22, n. 52, p. 8394, doi. 10.1038/sj.onc.1206908
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- Publication type:
- Article
The role of p53 in chemosensitivity and radiosensitivity.
- Published in:
- Oncogene, 2003, v. 22, n. 47, p. 7486, doi. 10.1038/sj.onc.1206949
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- Publication type:
- Article
P53 and radiation responses.
- Published in:
- Oncogene, 2003, v. 22, n. 37, p. 5774, doi. 10.1038/sj.onc.1206677
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- Publication type:
- Article
Acute overexpression of wt p53 facilitates anticancer drug-induced death of cancer and normal cells.
- Published in:
- International Journal of Cancer, 1998, v. 75, n. 6, p. 933, doi. 10.1002/(SICI)1097-0215(19980316)75:6<933::AID-IJC17>3.0.CO;2-3
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- Publication type:
- Article
In vitro evaluation of a p53-expressing adenovirus as an anti-cancer drug.
- Published in:
- International Journal of Cancer, 1996, v. 67, n. 3, p. 386, doi. 10.1002/(SICI)1097-0215(19960729)67:3<386::AID-IJC13>3.0.CO;2-6
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- Publication type:
- Article
Derangement of growth and differentiation control in oncogenesis.
- Published in:
- BioEssays, 2002, v. 24, n. 1, p. 83, doi. 10.1002/bies.10036
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- Publication type:
- Article
Preclinical Synergistic Combination Therapy of Lurbinectedin with Irinotecan and 5-Fluorouracil in Pancreatic Cancer.
- Published in:
- Current Oncology, 2023, v. 30, n. 11, p. 9611, doi. 10.3390/curroncol30110696
- By:
- Publication type:
- Article
Stroma Formation and Angiogenesis by Overexpression of Growth Factors, Cytokines, and Proteolytic Enzymes in Human Skin Grafted to SCID Mice.
- Published in:
- Journal of Investigative Dermatology, 2003, v. 120, n. 4, p. 683, doi. 10.1046/j.1523-1747.2003.12112.x
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- Publication type:
- Article
Tat-binding protein-1, a component of the 26S proteasome, contributes to the E3 ubiquitin ligase function of the von Hippel-Lindau protein.
- Published in:
- Nature Genetics, 2003, v. 35, n. 3, p. 229, doi. 10.1038/ng1254
- By:
- Publication type:
- Article
Molecular differences between lymph nodes and distant metastases compared with primaries in colorectal cancer patients.
- Published in:
- NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00230-y
- By:
- Publication type:
- Article
Dual Checkpoint Inhibition with Ipilimumab plus Nivolumab After Progression on Sequential PD‐1/PDL‐1 Inhibitors Pembrolizumab and Atezolizumab in a Patient with Lynch Syndrome, Metastatic Colon, and Localized Urothelial Cancer.
- Published in:
- Oncologist, 2019, v. 24, n. 11, p. 1416, doi. 10.1634/theoncologist.2018-0686
- By:
- Publication type:
- Article
ERBB family fusions are recurrent and actionable oncogenic targets across cancer types.
- Published in:
- Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1115405
- By:
- Publication type:
- Article
Anti-cancer immune responses to DNA damage response inhibitors: Molecular mechanisms and progress toward clinical translation.
- Published in:
- Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.998388
- By:
- Publication type:
- Article
Pioglitazone Inhibits Growth of Carcinoid Cells and Promotes TRAIL-Induced Apoptosis by Induction of p21[sup waf1/cip1].
- Published in:
- Digestion, 2001, v. 64, n. 2, p. 75, doi. 10.1159/000048843
- By:
- Publication type:
- Article
Sorafenib Sensitizes Solid Tumors to Apo2L/TRAIL and Apo2L/TRAIL Receptor Agonist Antibodies by the Jak2-Stat3-Mcl1 Axis.
- Published in:
- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0075414
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- Publication type:
- Article
The Akt Inhibitor ISC-4 Synergizes with Cetuximab in 5-FU-Resistant Colon Cancer.
- Published in:
- PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059380
- By:
- Publication type:
- Article
Selective Small Molecule Stat3 Inhibitor Reduces Breast Cancer Tumor- Initiating Cells and Improves Recurrence Free Survival in a Human-Xenograft Model.
- Published in:
- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0030207
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- Publication type:
- Article
p53-Dependent and p53-independent induction of insulin-like growth factor binding protein-3 by deoxyribonucleic acid damage and hypoxia.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Advanced Strategies for Therapeutic Targeting of Wild-Type and Mutant p53 in Cancer.
- Published in:
- Biomolecules (2218-273X), 2022, v. 12, n. 4, p. 548, doi. 10.3390/biom12040548
- By:
- Publication type:
- Article
Absence of Biomarker-Driven Treatment Options in Small Cell Lung Cancer, and Selected Preclinical Candidates for Next Generation Combination Therapies.
- Published in:
- Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.747180
- By:
- Publication type:
- Article
ERK and MDM2 prey on FOXO3a.
- Published in:
- Nature Cell Biology, 2008, v. 10, n. 2, p. 125, doi. 10.1038/ncb0208-125
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- Publication type:
- Article
Critical role for Daxx in regulating Mdm2.
- Published in:
- Nature Cell Biology, 2006, v. 8, n. 8, p. 855, doi. 10.1038/ncb1442
- By:
- Publication type:
- Article
BID regulation by p53 contributes to chemosensitivity.
- Published in:
- Nature Cell Biology, 2002, v. 4, n. 11, p. 842, doi. 10.1038/ncb866
- By:
- Publication type:
- Article