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Synthesis and Conformational Analysis of Sterically Congested (4R)-(--)-1-(2,4,6-Trimethylbenzenesulfonyl)-3-n-butyryl-4-tert-butyl-2-imidazolidinone: X-Ray Crystallography and Semiempirical Calculations.
Published in:
Journal of Chemistry, 2014, p. 1, doi. 10.1155/2014/173902
By:
- Al-Swaidan, Ibrahim A.;
- El-Azab, Adel S.;
- Alanazi, Amer M.;
- Abdel-Aziz, Alaa A.-M.
Publication type:
Article
An Alternative Route for Synthesis of Chiral 4-Substituted 1-Arenesulfonyl-2-imidazolidinones: Unusual Utility of (4S,5S)- and (4R,5R)-4,5-Dimethoxy-2-imidazolidinones and X-Ray Crystallography.
Published in:
Journal of Chemistry, 2013, p. 1, doi. 10.1155/2013/349519
By:
- Al-Swaidan, Ibrahim A.;
- Alanazi, Amer M.;
- El-Azab, Adel S.;
- Abdel-Aziz, Alaa A.-M.
Publication type:
Article
Hirshfeld Surface, Molecular Docking Study, Spectroscopic Characterization and NLO Profile of 2-Methoxy-4,6- Diphenylnicotinonitrile.
Published in:
ChemistrySelect, 2019, v. 4, n. 33, p. 9857, doi. 10.1002/slct.201902391
By:
- Gökce, Halil;
- Sert, Yusuf;
- Alpaslan, Gökhan;
- El-Azab, Adel S.;
- Alanazi, Mohammed M.;
- Al-Agamy, Mohamed H. M.;
- Abdel-Aziz, Alaa A. -M.
Publication type:
Article
Structural, Spectroscopic, Electronic and Molecular Docking Studies on (11R,12 S)‐16‐Aminotetracyclo[6.6.2.02,7.09,14]hexadeca‐2(7),3,5,9(14),10,12‐hexaen‐15‐ol.
Published in:
ChemistrySelect, 2019, v. 4, n. 3, p. 825, doi. 10.1002/slct.201803732
By:
- Kaya, Serdal;
- Gökce, Halil;
- El‐Azab, Adel S.;
- Sert, Yusuf;
- Alanazi, Mohammed M.;
- Öztürk, Nuri;
- Al‐Agamy, Mohamed H. M.;
- Abdel‐Aziz, Alaa A.‐M.
Publication type:
Article
4‐[(1, 3‐Dioxoisoindolin‐2‐yl)methyl]benzenesulfonamide: Full Structural and Spectroscopic Characterization and Molecular Docking with Carbonic Anhydrase II.
Published in:
ChemistrySelect, 2018, v. 3, n. 35, p. 10113, doi. 10.1002/slct.201802484
By:
- Gökce, Halil;
- Öztürk, Nuri;
- Sert, Yusuf;
- El‐Azab, Adel S.;
- A. AlSaif, Nawaf;
- Abdel‐Aziz, Alaa A.‐M.
Publication type:
Article
A Liquid Chromatography Tandem Mass Spectrometry Method for the Simultaneous Estimation of the Dopamine Receptor Antagonist LE300 and Its N-methyl Metabolite in Plasma: Application to a Pharmacokinetic Study.
Published in:
Molecules, 2023, v. 28, n. 4, p. 1553, doi. 10.3390/molecules28041553
By:
- Hefnawy, Mohamed M.;
- Attwa, Mohamed W.;
- Alzamil, Adeeba A.;
- El-Gendy, Manal A.;
- El-Azab, Adel S.;
- Jardan, Yousef A. Bin;
- El-Gamal, Ali A.
Publication type:
Article
Synthesis, Cytotoxic Evaluation, and Structure-Activity Relationship of Substituted Quinazolinones as Cyclin-Dependent Kinase 9 Inhibitors.
Published in:
Molecules, 2023, v. 28, n. 1, p. 120, doi. 10.3390/molecules28010120
By:
- Alkahtani, Hamad M.;
- Zen, Amer Alhaj;
- Obaidullah, Ahmad J.;
- Alanazi, Mohammed M.;
- Almehizia, Abdulrahman A.;
- Ansari, Siddique Akber;
- Aleanizy, Fadilah Sfouq;
- Alqahtani, Fulwah Yahya;
- Aldossari, Rana M.;
- Algamdi, Raghad Abdullah;
- Al-Rasheed, Lamees S.;
- Abdel-Hamided, Sami G.;
- Abdel-Aziz, Alaa A.-M.;
- El-Azab, Adel S.
Publication type:
Article
A Rapid and Sensitive Liquid Chromatography-Tandem Mass Spectrometry Bioanalytical Method for the Quantification of Encorafenib and Binimetinib as a First-Line Treatment for Advanced (Unresectable or Metastatic) Melanoma—Application to a Pharmacokinetic Study
Published in:
Molecules, 2023, v. 28, n. 1, p. 79, doi. 10.3390/molecules28010079
By:
- Hefnawy, Mohamed M.;
- Alanazi, Mohammed M.;
- Al-Hossaini, Abdullah M.;
- Alnasser, Abdulaziz I.;
- El-Azab, Adel S.;
- Jardan, Yousef A. Bin;
- Attwa, Mohamed W.;
- El-Gendy, Manal A.
Publication type:
Article
Carbonic Anhydrase Inhibition Activities of Schiff's Bases Based on Quinazoline-Linked Benzenesulfonamide.
Published in:
Molecules, 2022, v. 27, n. 22, p. 7703, doi. 10.3390/molecules27227703
By:
- El-Azab, Adel S.;
- Abdel-Aziz, Alaa A.-M.;
- Ghabbour, Hazem A.;
- Bua, Silvia;
- Nocentini, Alessio;
- Alkahtani, Hamad M.;
- Alsaif, Nawaf A.;
- Al-Agamy, Mohamed H. M.;
- Supuran, Claudiu T.
Publication type:
Article
Co-Inhibition of P-gp and Hsp90 by an Isatin-Derived Compound Contributes to the Increase of the Chemosensitivity of MCF7/ADR-Resistant Cells to Doxorubicin.
Published in:
Molecules, 2022, v. 27, n. 1, p. 90, doi. 10.3390/molecules27010090
By:
- Abdalla, Ashraf N.;
- Di Stefano, Miriana;
- Poli, Giulio;
- Tuccinardi, Tiziano;
- Bader, Ammar;
- Vassallo, Antonio;
- Abdallah, Mohamed E.;
- El-Readi, Mahmoud Zaki;
- Refaat, Bassem;
- Algarni, Alanood S.;
- Ahmad, Rizwan;
- Alkahtani, Hamad M.;
- Abdel-Aziz, Alaa A.-M.;
- El-Azab, Adel S.;
- Alqathama, Aljawharah
Publication type:
Article
Remarkable Conversion of 2-Thioxo-2,3-dihydroquinazolin-4(1H)-ones into the Corresponding Quinazoline-2,4(1H,3H)-diones: Spectroscopic Analysis and X-Ray Crystallography.
Published in:
Journal of Chemistry, 2021, p. 1, doi. 10.1155/2021/6612177
By:
- El-Azab, Adel S.;
- Khalil, Nasr Y.;
- Abdel-Aziz, Alaa A.-M.
Publication type:
Article
AMANTADINE AMIDES PRODRUGS AS HEPATIC DELIVERY SYSTEMS TO ENHANCE ITS ACTIVITY AGAINST HCV.
Published in:
Digest Journal of Nanomaterials & Biostructures (DJNB), 2011, v. 6, n. 4, p. 1675
By:
- Aboul-Fadl, Tarek;
- Sheha, Mahmoud M.;
- El-Azab, Adel S.;
- Abdel-Aziz, Hatem A.
Publication type:
Article
Crystal structure of 6-iodo-3-phenyl-2-propylquinazolin-4(3H)-one, C17H15IN2O.
Published in:
Zeitschrift für Kristallographie / New Crystal Structures, 2020, v. 235, n. 2, p. 489, doi. 10.1515/ncrs-2019-0788
By:
- El-Azab, Adel S.;
- Ghabbour, Hazem A.;
- Abdel-Aziz, Alaa A.-M.;
- Alkahtani, Hamad M.
Publication type:
Article
Crystal structure of (E)-N′-((4-aminophenyl)sulfonyl)-N,N-dimethylformimidamide, C9H13N3O2S.
Published in:
Zeitschrift für Kristallographie / New Crystal Structures, 2020, v. 235, n. 2, p. 483, doi. 10.1515/ncrs-2019-0781
By:
- Abdel-Aziz, Alaa A.-M.;
- El-Azab, Adel S.;
- Ghabbour, Hazem A.;
- Obaidullaha, Ahmad J.
Publication type:
Article
Synthesis, Anticancer Screening of Some Novel Trimethoxy Quinazolines and VEGFR2, EGFR Tyrosine Kinase Inhibitors Assay; Molecular Docking Studies.
Published in:
Molecules, 2021, v. 26, n. 10, p. 2992, doi. 10.3390/molecules26102992
By:
- Altamimi, Abdulmalik S.;
- El-Azab, Adel S.;
- Abdelhamid, Sami G.;
- Alamri, Mubarak A.;
- Bayoumi, Ashraf H.;
- Alqahtani, Safar M.;
- Alabbas, Alhumaidi B.;
- Altharawi, Ali I.;
- Alossaimi, Manal A.;
- Mohamed, Menshawy A.;
- Gauld, James
Publication type:
Article
Synergistic Anti Leukemia Effect of a Novel Hsp90 and a Pan Cyclin Dependent Kinase Inhibitors.
Published in:
Molecules, 2020, v. 25, n. 9, p. 2220, doi. 10.3390/molecules25092220
By:
- Abdalla, Ashraf N.;
- Abdallah, Mohamed E.;
- Aslam, Akhmed;
- Bader, Ammar;
- Vassallo, Antonio;
- Tommasi, Nunziatina De;
- Malki, Waleed H.;
- Gouda, Ahmed M.;
- Mukhtar, Mohammed H.;
- El-Readi, Mahmoud Zaki;
- Alkahtani, Hamad M.;
- Abdel-Aziz, Alaa A.-M.;
- El-Azab, Adel S.;
- Tylkowski, Bartosz;
- Bajek, Anna;
- Roszkowski, Krzysztof
Publication type:
Article
Synthesis of hapten, generation of specific polyclonal antibody and development of ELISA with high sensitivity for therapeutic monitoring of crizotinib.
Published in:
PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0212048
By:
- Al-Shehri, Mona M.;
- El-Azab, Adel S.;
- El-Gendy, Manal A.;
- Hamidaddin, Mohammed A.;
- Darwish, Ibrahim A.
Publication type:
Article

Found: 17

Synthesis and Conformational Analysis of Sterically Congested (4R)-(--)-1-(2,4,6-Trimethylbenzenesulfonyl)-3-n-butyryl-4-tert-butyl-2-imidazolidinone: X-Ray Crystallography and Semiempirical Calculations.

An Alternative Route for Synthesis of Chiral 4-Substituted 1-Arenesulfonyl-2-imidazolidinones: Unusual Utility of (4S,5S)- and (4R,5R)-4,5-Dimethoxy-2-imidazolidinones and X-Ray Crystallography.

Hirshfeld Surface, Molecular Docking Study, Spectroscopic Characterization and NLO Profile of 2-Methoxy-4,6- Diphenylnicotinonitrile.

Structural, Spectroscopic, Electronic and Molecular Docking Studies on (11R,12 S)‐16‐Aminotetracyclo[6.6.2.0<sup>2,7</sup>.0<sup>9,14</sup>]hexadeca‐2(7),3,5,9(14),10,12‐hexaen‐15‐ol.

4‐[(1, 3‐Dioxoisoindolin‐2‐yl)methyl]benzenesulfonamide: Full Structural and Spectroscopic Characterization and Molecular Docking with Carbonic Anhydrase II.

A Liquid Chromatography Tandem Mass Spectrometry Method for the Simultaneous Estimation of the Dopamine Receptor Antagonist LE300 and Its N-methyl Metabolite in Plasma: Application to a Pharmacokinetic Study.

Synthesis, Cytotoxic Evaluation, and Structure-Activity Relationship of Substituted Quinazolinones as Cyclin-Dependent Kinase 9 Inhibitors.

A Rapid and Sensitive Liquid Chromatography-Tandem Mass Spectrometry Bioanalytical Method for the Quantification of Encorafenib and Binimetinib as a First-Line Treatment for Advanced (Unresectable or Metastatic) Melanoma—Application to a Pharmacokinetic Study

Carbonic Anhydrase Inhibition Activities of Schiff's Bases Based on Quinazoline-Linked Benzenesulfonamide.

Co-Inhibition of P-gp and Hsp90 by an Isatin-Derived Compound Contributes to the Increase of the Chemosensitivity of MCF7/ADR-Resistant Cells to Doxorubicin.

Remarkable Conversion of 2-Thioxo-2,3-dihydroquinazolin-4(1H)-ones into the Corresponding Quinazoline-2,4(1H,3H)-diones: Spectroscopic Analysis and X-Ray Crystallography.

AMANTADINE AMIDES PRODRUGS AS HEPATIC DELIVERY SYSTEMS TO ENHANCE ITS ACTIVITY AGAINST HCV.

Crystal structure of 6-iodo-3-phenyl-2-propylquinazolin-4(3H)-one, C<sub>17</sub>H<sub>15</sub>IN<sub>2</sub>O.

Crystal structure of (E)-N′-((4-aminophenyl)sulfonyl)-N,N-dimethylformimidamide, C<sub>9</sub>H<sub>13</sub>N<sub>3</sub>O<sub>2</sub>S.

Synthesis, Anticancer Screening of Some Novel Trimethoxy Quinazolines and VEGFR2, EGFR Tyrosine Kinase Inhibitors Assay; Molecular Docking Studies.

Synergistic Anti Leukemia Effect of a Novel Hsp90 and a Pan Cyclin Dependent Kinase Inhibitors.

Synthesis of hapten, generation of specific polyclonal antibody and development of ELISA with high sensitivity for therapeutic monitoring of crizotinib.