Works by El fadili, Mohamed

Results: 31

In silico design of novel pyridazine derivatives as balanced multifunctional agents against Alzheimer's disease.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-98182-x

By:

Aloui, Mourad;
El fadili, Mohamed;
Mujwar, Somdutt;
Er-rajy, Mohammed;
Abuelizz, Hatem A.;
Er-rahmani, Sara;
Zarougui, Sara;
Menana, Elhalaoui

Publication type:

Article

Exploring the essence of celery seeds (Apium graveolens L.): Innovations in microwave-assisted hydrodistillation for essential oil extraction using in vitro, in vivo and in silico studies.

Published in:

Arabian Journal of Chemistry, 2024, v. 17, n. 5, p. N.PAG, doi. 10.1016/j.arabjc.2024.105726

By:

Nouioura, Ghizlane;
El fadili, Mohamed;
Ghneim, Hazem K.;
Zbadi, Latifa;
Maache, Souad;
Zouirech, Otmane;
Danouche, Mohamed;
Aboul-Soud, Mourad A.M.;
Giesy, John P.;
Lyoussi, Badiaa;
Derwich, Elhoussine

Publication type:

Article

Design of novel anti-cancer agents targeting COX-2 inhibitors based on computational studies.

Published in:

Arabian Journal of Chemistry, 2023, v. 16, n. 10, p. N.PAG, doi. 10.1016/j.arabjc.2023.105193

By:

Er-rajy, Mohammed;
El fadili, Mohamed;
Mujwar, Somdutt;
Imtara, Hamada;
Al kamaly, Omkulthom;
Zuhair Alshawwa, Samar;
Nasr, Fahd A.;
Zarougui, Sara;
Elhallaoui, Menana

Publication type:

Article

In-silico screening based on molecular simulations of 3,4-disubstituted pyrrolidine sulfonamides as selective and competitive GlyT1 inhibitors.

Published in:

Arabian Journal of Chemistry, 2023, v. 16, n. 10, p. N.PAG, doi. 10.1016/j.arabjc.2023.105105

By:

El fadili, Mohamed;
Er-rajy, Mohammed;
Ali Eltayb, Wafa;
Kara, Mohammed;
Assouguem, Amine;
Saleh, Asmaa;
Al Kamaly, Omkulthom;
Zarougui, Sara;
Elhallaoui, Menana

Publication type:

Article

Author Correction: Comprehensive analysis of different solvent extracts of Ferula communis L. fruit reveals phenolic compounds and their biological properties via in vitro and in silico assays.

Published in:

2024

By:

Nouioura, Ghizlane;
El fadili, Mohamed;
El Barnossi, Azeddin;
Loukili, El Hassania;
Laaroussi, Hassan;
Bouhrim, Mohammed;
Giesy, John P.;
Aboul-Soud, Mourad A. M.;
Al-Sheikh, Yazeed A.;
Lyoussi, Badiaa;
Derwich, El houssine

Publication type:

Correction Notice

Comprehensive analysis of different solvent extracts of Ferula communis L. fruit reveals phenolic compounds and their biological properties via in vitro and in silico assays.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-59087-3

By:

Nouioura, Ghizlane;
El fadili, Mohamed;
El Barnossi, Azeddin;
Loukili, El Hassania;
Laaroussi, Hassan;
Bouhrim, Mohammed;
Giesy, John P.;
Aboul-Soud, Mourad A. M.;
Al-Sheikh, Yazeed A.;
Lyoussi, Badiaa;
Derwich, El houssine

Publication type:

Article

GC/MS Profiling, In Vitro Antidiabetic Efficacy of Origanum compactum Benth. Essential Oil and In Silico Molecular Docking of Its Major Bioactive Compounds.

Published in:

Catalysts (2073-4344), 2023, v. 13, n. 11, p. 1429, doi. 10.3390/catal13111429

By:

Assaggaf, Hamza;
El Hachlafi, Naoufal;
El fadili, Mohamed;
Elbouzidi, Amine;
Ouassou, Hayat;
Jeddi, Mohamed;
Alnasser, Sulaiman Mohammed;
Qasem, Ahmed;
Attar, Ammar;
AL-Farga, Ammar;
Alghamdi, Othman A.;
Mehana, Elsayed Eldeeb;
Mrabti, Hanae Naceiri

Publication type:

Article

QSAR, ADMET In Silico Pharmacokinetics, Molecular Docking and Molecular Dynamics Studies of Novel Bicyclo (Aryl Methyl) Benzamides as Potent GlyT1 Inhibitors for the Treatment of Schizophrenia.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 6, p. 670, doi. 10.3390/ph15060670

By:

El fadili, Mohamed;
Er-Rajy, Mohammed;
Kara, Mohammed;
Assouguem, Amine;
Belhassan, Assia;
Alotaibi, Amal;
Mrabti, Nidal Naceiri;
Fidan, Hafize;
Ullah, Riaz;
Ercisli, Sezai;
Zarougui, Sara;
Elhallaoui, Menana

Publication type:

Article

Chemical, Mineralogical, and Biological Properties of Pistacia atlantica subsp. atlantica Essential Oils from the Middle Atlas of Morocco.

Published in:

Horticulturae, 2025, v. 11, n. 3, p. 265, doi. 10.3390/horticulturae11030265

By:

Bassouya, Mohammed;
Chedadi, Mohamed;
El fadili, Mohamed;
Zahra, Jawhari Fatima;
El-byari, Younesse;
Shahat, Abdelaaty A.;
Morya, Sonia;
El Moussaoui, Abdelfattah;
Kara, Mohammed;
Bari, Amina

Publication type:

Article

3D-QSAR Studies, Molecular Docking, Molecular Dynamic Simulation, and ADMET Proprieties of Novel Pteridinone Derivatives as PLK1 Inhibitors for the Treatment of Prostate Cancer.

Published in:

Life (2075-1729), 2023, v. 13, n. 1, p. 127, doi. 10.3390/life13010127

By:

Er-rajy, Mohammed;
El fadili, Mohamed;
Imtara, Hamada;
Saeed, Aamir;
Ur Rehman, Abid;
Zarougui, Sara;
Abdullah, Shaef A.;
Alahdab, Ahmad;
Parvez, Mohammad Khalid;
Elhallaoui, Menana

Publication type:

Article

GC-MS Profiling, In Vitro and In Silico Antibacterial and Antioxidant Potential of Origanum elongatum Essential Oil: Novel Source against Phytopathogenic Bacteria.

Published in:

Phyton (0031-9457), 2025, v. 94, n. 2, p. 481, doi. 10.32604/phyton.2025.059841

By:

Batbat, Amine;
Fadili, Mohamed El;
Hachlafi, Naoufal El;
Elbouzidi, Amine;
Hmimen, Chaymae;
Yahyaoui, Hiba;
Jeddi, Samir;
Benbouazza, Abdellatif;
Fikri-Benbrahim, Kawtar;
Addi, Mohamed;
Al-Mijalli, Samiah Hamad;
Habbadi, Khaoula;
Greche, Hassane

Publication type:

Article

In-silico screening and ADMET evaluation of therapeutic MAO-B inhibitors against Parkinson disease.

Published in:

Intelligent Pharmacy, 2024, v. 2, n. 4, p. 554, doi. 10.1016/j.ipha.2023.12.008

By:

Ajala, Abduljelil;
Wafa Ali Eltayb;
Abatyough, Terungwa Michael;
Ejeh, Stephen;
El fadili, Mohamed;
Otaru, Habiba Asipita;
Edache, Emmanuel Israel;
Abdulganiyyu, A. Ibrahim;
Areguamen, Omole Isaac;
Patil, Shashank M.;
Ramu, Ramith

Publication type:

Article

Design of novel pyrazole and benzofuran-based derivatives as potent acetylcholinesterase inhibitors for Alzheimer's disease management.

Published in:

Frontiers in Chemistry, 2025, p. 1, doi. 10.3389/fchem.2025.1614462

By:

El Fadili, Mohamed;
Ez-Zoubi, Amine;
Aloui, Mourad;
Mujwar, Somdutt;
Abuelizz, Hatem A.;
Elhalaoui, Menana;
Amin, Adnan

Publication type:

Article

Design and evaluation of novel triazole derivatives as potential anti-gout inhibitors: a comprehensive molecular modeling study.

Published in:

Frontiers in Chemistry, 2025, p. 1, doi. 10.3389/fchem.2025.1518777

By:

Er-rajy, Mohammed;
El fadili, Mohamed;
Zarougui, Sara;
Mujwar, Somdutt;
Aloui, Mourad;
Zerrouk, Mohammed;
Hammouti, Belkheir;
Rhazi, Larbi;
Sabbahi, Rachid;
Alanazi, Mohammed M.;
Azzaoui, Khalil;
Salghi, Rachid;
Elhallaoui, Menana

Publication type:

Article

Molecular characterization, chemical profile and biological properties of essential oils from Chamaemelum nobile (L.) flowers of Morocco: in vitro and in silico studies.

Published in:

Frontiers in Chemistry, 2025, p. 1, doi. 10.3389/fchem.2025.1539872

By:

El-Assri, El-Mehdi;
El-Assri, Youssef;
El Brahimi, Rajae;
El fadili, Mohamed;
Baghouz, Asmae;
Abuelizz, Hatem A.;
Er-Rahmani, Sara;
Lahkimi, Amal;
Bouia, Abdelhak

Publication type:

Article

Ferula communis leaf extract: antioxidant capacity, UHPLC–MS/MS analysis, and in vivo and in silico toxicity investigations.

Published in:

Frontiers in Chemistry, 2025, p. 1, doi. 10.3389/fchem.2024.1485463

By:

Ed-Dahmani, Imad;
El Fadili, Mohamed;
Nouioura, Ghizlane;
Kandsi, Fahd;
Atki, Yassine El;
Abuelizz, Hatem A.;
Conte, Raffaele;
Zahra Lafdil, Fatima;
Taleb, Abdeslam;
Abdellaoui, Abdelfattah;
Taleb, Mustapha

Publication type:

Article

Phytochemical and physicochemical studies of different apple varieties grown in Morocco.

Published in:

Open Chemistry, 2024, v. 22, n. 1, p. 1, doi. 10.1515/chem-2023-0205

By:

Mohammed, Kara;
Saghrouchni, Hamza;
El Abdali, Youness;
Amine, Assouguem;
Haoudi, Nouha;
El fadili, Mohamed;
Amar, Aya;
Hamijo, Tareq;
Var, Isil;
Ullah, Riaz;
Rachid, Zerhouni Abdou;
Jamila, Bahhou

Publication type:

Article

Unveiling the Phenolic Profiling of Moroccan Ferula communis L. Fruits: A Combination of In Silico and In Vivo Protective Effect Against Methotrexate‐Induced Hepato‐Renal Dysfunction.

Published in:

Journal of Food Biochemistry, 2025, v. 2025, p. 1, doi. 10.1155/jfbc/1106215

By:

Nouioura, Ghizlane;
Fadili, Mohamed El;
Bouhrim, Mohamed;
Loukili, El Hassania;
Ghneim, Hazem K.;
Aboul-Soud, Mourad A. M.;
Giesy, John P.;
Lyoussi, Badiaa;
Derwich, Elhoussine;
Sakar, El Hassan

Publication type:

Article

Dysphania ambrosioides (L.) Mosyakin and Clemants: bridging traditional knowledge, photochemistry, preclinical investigations, and toxicological validation for health benefits.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2024, v. 397, n. 2, p. 969, doi. 10.1007/s00210-023-02658-4

By:

Kandsi, Fahd;
Lafdil, Fatima Zahra;
El Hachlafi, Naoufal;
Jeddi, Mohamed;
Bouslamti, Mohammed;
El Fadili, Mohamed;
Seddoqi, Sara;
Gseyra, Nadia

Publication type:

Article

Exploring Phytochemical Composition, Antioxidant, Antibacterial Properties, and in Silico Study of Aqueous Leaf Extract of Pistacia lentiscus L. from the Eastern Region of Morocco.

Published in:

Tropical Journal of Natural Product Research, 2024, v. 8, n. 4, p. 6891, doi. 10.26538/tjnpr/v8i4.20

By:

Seddoqi, Sara;
Aouinti, Fatima;
El fadili, Mohamed;
Conte, Raffaele;
Elhachlafi, Naoufal;
Gseyra, Nadia

Publication type:

Article

Evaluation of Polyphenolic Content, Antioxidant and Antimicrobial Activities, and Toxicity Study of Ferula communis L. Fruits.

Published in:

Tropical Journal of Natural Product Research, 2024, v. 8, n. 2, p. 6423, doi. 10.26538/tjnpr/v8i2.34

By:

Ed-Dahmani, Imad;
Kara, Mohammed;
Lfitat, Aziza;
Touijer, Hanane;
Bousraf, Fatima Z.;
Slighoua, Meryem;
Nouioura, Ghizlane;
El Atki, Yassine;
El Fadili, Mohamed;
Taleb, Mustapha;
Abdellaoui, Abdelfattah

Publication type:

Article

Beta‐Cyclodextrin Inclusion Complexes with Phenolic Synthetic Antioxidants: Synthesis, Spectroscopic Characterisation, Molecular Modeling, and Activity Efficiency.

Published in:

ChemistrySelect, 2025, v. 10, n. 10, p. 1, doi. 10.1002/slct.202405310

By:

Ez‐zoubi, Amine;
Boutahiri, Naima;
El fadili, Mohamed;
Sghyar, Riham;
Mujwar, Somdutt;
Moustaid, Wafae;
El‐Mrabet, Ayoub;
Farah, Abdellah

Publication type:

Article

Chemical Composition, Antioxidant Properties, Acute Toxicity, and Pharmacokinetic Evaluation of Aqueous Extract of Roots of Ferula communis L.

Published in:

ChemistrySelect, 2024, v. 9, n. 43, p. 1, doi. 10.1002/slct.202403973

By:

Ed‐Dahmani, Imad;
El fadili, Mohamed;
Nouioura, Ghizlane;
El Atki, Yassine;
Kandsi, Fahd;
Conte, Raffaele;
Lafdil, Fatima Zahra;
Mssillou, Ibrahim;
Al‐Sheikh, Yazeed A.;
Aboul‐Soud, Mourad A. M.;
Giesy, John P.;
Abdellaoui, Abdelfattah;
Taleb, Mustapha

Publication type:

Article

3D-QSAR, ADME-Tox In Silico Prediction and Molecular Docking Studies for Modeling the Analgesic Activity against Neuropathic Pain of Novel NR2B-Selective NMDA Receptor Antagonists.

Published in:

Processes, 2022, v. 10, n. 8, p. 1462, doi. 10.3390/pr10081462

By:

El fadili, Mohamed;
Er-rajy, Mohammed;
Imtara, Hamada;
Kara, Mohammed;
Zarougui, Sara;
Altwaijry, Najla;
Al kamaly, Omkulthom;
Al Sfouk, Aisha;
Elhallaoui, Menana

Publication type:

Article

Coriandrum sativum L., essential oil as a promising source of bioactive compounds with GC/MS, antioxidant, antimicrobial activities: in vitro and in silico predictions.

Published in:

Frontiers in Chemistry, 2024, p. 1, doi. 10.3389/fchem.2024.1369745

By:

Nouioura, Ghizlane;
fadili, Mohamed El;
Hachlafi, Naoufal El;
Maache, Souad;
Mssillou, Ibrahim;
Abuelizz, Hatem A.;
Lafdil, Fatima Zahra;
Er-rahmani, Sara;
Lyoussi, Badiaa;
Derwich, Elhoussine;
Yener, Ismail

Publication type:

Article

3D computer modeling of inhibitors targeting the MCF-7 breast cancer cell line.

Published in:

Frontiers in Chemistry, 2024, p. 01, doi. 10.3389/fchem.2024.1384832

By:

Zarougui, Sara;
Er-Rajy, Mohammed;
Faris, Abdelmoujoud;
Imtara, Hamada;
El fadili, Mohamed;
Qurtam, Ashraf Ahmed;
Nasr, Fahd A.;
Al-Zharani, Mohammed;
Elhallaoui, Menana;
Darwish, Khaled Mohamed;
Dalal, Vikram

Publication type:

Article

An in-silico investigation based on molecular simulations of novel and potential brain-penetrant GluN2B NMDA receptor antagonists as anti-stroke therapeutic agents.

Published in:

Journal of Biomolecular Structure & Dynamics, 2024, v. 42, n. 12, p. 6174, doi. 10.1080/07391102.2023.2232024

By:

El fadili, Mohamed;
Er-rajy, Mohammed;
Ali Eltayb, Wafa;
Kara, Mohammed;
Imtara, Hamada;
Zarougui, Sara;
Al-Hoshani, Nawal;
Hamadi, Abdullah;
Elhallaoui, Menana

Publication type:

Article

Design of novel anti-cancer drugs targeting TRKs inhibitors based 3D QSAR, molecular docking and molecular dynamics simulation.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 21, p. 11657, doi. 10.1080/07391102.2023.2170471

By:

Er-rajy, Mohammed;
El fadili, Mohamed;
Mujwar, Somdutt;
Zarougui, Sara;
Elhallaoui, Menana

Publication type:

Article

New Triazole-Isoxazole Hybrids as Antibacterial Agents: Design, Synthesis, Characterization, In Vitro, and In Silico Studies.

Published in:

Molecules, 2024, v. 29, n. 11, p. 2510, doi. 10.3390/molecules29112510

By:

Bouzammit, Rachid;
Belchkar, Salim;
El fadili, Mohamed;
Kanzouai, Youssra;
Mujwar, Somdutt;
Alanazi, Mohammed M.;
Chalkha, Mohammed;
Nakkabi, Asmae;
Bakhouch, Mohamed;
Gal, Emese;
Gaina, Luiza Ioana;
al houari, Ghali

Publication type:

Article

Contribution to the Evaluation of Physicochemical Properties, Total Phenolic Content, Antioxidant Potential, and Antimicrobial Activity of Vinegar Commercialized in Morocco.

Published in:

Molecules, 2022, v. 27, n. 3, p. 770, doi. 10.3390/molecules27030770

By:

Kara, Mohammed;
Assouguem, Amine;
Fadili, Mohamed El;
Benmessaoud, Safaâ;
Alshawwa, Samar Zuhair;
Kamaly, Omkulthom Al;
Saghrouchni, Hamza;
Zerhouni, Abdou Rachid;
Bahhou, Jamila

Publication type:

Article

In silico insights into the design of novel NR2B-selective NMDA receptor antagonists: QSAR modeling, ADME-toxicity predictions, molecular docking, and molecular dynamics investigations.

Published in:

BMC Chemistry, 2024, v. 18, n. 1, p. 1, doi. 10.1186/s13065-024-01248-6

By:

El fadili, Mohamed;
Er-rajy, Mohammed;
Mujwar, Somdutt;
Ajala, Abduljelil;
Bouzammit, Rachid;
Kara, Mohammed;
Abuelizz, Hatem A.;
Er-rahmani, Sara;
Elhallaoui, Menana

Publication type:

Article