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Homologous recombination deficiency derived from whole-genome sequencing predicts platinum response in triple-negative breast cancers.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37537-2
By:
- ter Brugge, Petra;
- Moser, Sarah C.;
- Bièche, Ivan;
- Kristel, Petra;
- Ibadioune, Sabrina;
- Eeckhoutte, Alexandre;
- de Bruijn, Roebi;
- van der Burg, Eline;
- Lutz, Catrin;
- Annunziato, Stefano;
- de Ruiter, Julian;
- Masliah Planchon, Julien;
- Vacher, Sophie;
- Courtois, Laura;
- El-Botty, Rania;
- Dahmani, Ahmed;
- Montaudon, Elodie;
- Morisset, Ludivine;
- Sourd, Laura;
- Huguet, Léa
Publication type:
Article
Oxidative phosphorylation is a metabolic vulnerability of endocrine therapy and palbociclib resistant metastatic breast cancers.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40022-5
By:
- El-Botty, Rania;
- Morriset, Ludivine;
- Montaudon, Elodie;
- Tariq, Zakia;
- Schnitzler, Anne;
- Bacci, Marina;
- Lorito, Nicla;
- Sourd, Laura;
- Huguet, Léa;
- Dahmani, Ahmed;
- Painsec, Pierre;
- Derrien, Heloise;
- Vacher, Sophie;
- Masliah-Planchon, Julien;
- Raynal, Virginie;
- Baulande, Sylvain;
- Larcher, Thibaut;
- Vincent-Salomon, Anne;
- Dutertre, Guillaume;
- Cottu, Paul
Publication type:
Article
Analysis of genomic and non-genomic signaling of estrogen receptor in PDX models of breast cancer treated with a combination of the PI3K inhibitor alpelisib (BYL719) and fulvestrant.
Published in:
2021
By:
- Jacquemetton, Julien;
- Kassem, Loay;
- Poulard, Coralie;
- Dahmani, Ahmed;
- De Plater, Ludmilla;
- Montaudon, Elodie;
- Sourd, Laura;
- Morisset, Ludivine;
- El Botty, Rania;
- Chateau-Joubert, Sophie;
- Vacher, Sophie;
- Bièche, Ivan;
- Treilleux, Isabelle;
- Trédan, Olivier;
- Marangoni, Elisabetta;
- Le Romancer, Muriel
Publication type:
journal article
Evaluation of Combined Chemotherapy and Genomic-Driven Targeted Therapy in Patient-Derived Xenografts Identifies New Therapeutic Approaches in Squamous Non-Small-Cell Lung Cancer Patients.
Published in:
Cancers, 2024, v. 16, n. 16, p. 2785, doi. 10.3390/cancers16162785
By:
- Decaudin, Didier;
- Némati, Fariba;
- Masliah Planchon, Julien;
- Seguin-Givelet, Agathe;
- Lefevre, Marine;
- Etienne, Vesnie;
- Ahnine, Harry;
- Peretti, Quentin;
- Sourd, Laura;
- El-Botty, Rania;
- Huguet, Lea;
- Lagha, Sarah;
- Hegarat, Nadia;
- Roman-Roman, Sergio;
- Bièche, Ivan;
- Girard, Nicolas;
- Montaudon, Elodie
Publication type:
Article
Dramatic In Vivo Efficacy of the EZH2-Inhibitor Tazemetostat in PBRM1 -Mutated Human Chordoma Xenograft.
Published in:
Cancers, 2022, v. 14, n. 6, p. 1486, doi. 10.3390/cancers14061486
By:
- Passeri, Thibault;
- Dahmani, Ahmed;
- Masliah-Planchon, Julien;
- Naguez, Adnan;
- Michou, Marine;
- El Botty, Rania;
- Vacher, Sophie;
- Bouarich, Rachida;
- Nicolas, André;
- Polivka, Marc;
- Franck, Coralie;
- Schnitzler, Anne;
- Némati, Fariba;
- Roman-Roman, Sergio;
- Bourdeaut, Franck;
- Adle-Biassette, Homa;
- Mammar, Hamid;
- Froelich, Sébastien;
- Bièche, Ivan;
- Decaudin, Didier
Publication type:
Article
PARP Inhibition Increases the Response to Chemotherapy in Uveal Melanoma.
Published in:
Cancers, 2019, v. 11, n. 6, p. 751, doi. 10.3390/cancers11060751
By:
- de Koning, Leanne;
- Decaudin, Didier;
- El Botty, Rania;
- Nicolas, André;
- Carita, Guillaume;
- Schuller, Mathieu;
- Ouine, Bérengère;
- Cartier, Aurélie;
- Naguez, Adnan;
- Fleury, Justine;
- Cooke, Vesselina;
- Wylie, Andrew;
- Smith, Paul;
- Marangoni, Elisabetta;
- Gentien, David;
- Meseure, Didier;
- Mariani, Pascale;
- Cassoux, Nathalie;
- Piperno-Neumann, Sophie;
- Roman-Roman, Sergio
Publication type:
Article
HORMAD1 overexpression predicts response to anthracycline–cyclophosphamide and survival in triple‐negative breast cancers.
Published in:
Molecular Oncology, 2023, v. 17, n. 10, p. 2017, doi. 10.1002/1878-0261.13412
By:
- El‐Botty, Rania;
- Vacher, Sophie;
- Mainguené, Juliette;
- Briaux, Adrien;
- Ibadioune, Sabrina;
- Dahmani, Ahmed;
- Montaudon, Elodie;
- Nemati, Fariba;
- Huguet, Léa;
- Sourd, Laura;
- Morriset, Ludivine;
- Château‐Joubert, Sophie;
- Dubois, Thierry;
- Maire, Virginie;
- Lidereau, Rosette;
- Rapinat, Audrey;
- Gentien, David;
- Coussy, Florence;
- Bièche, Ivan;
- Marangoni, Elisabetta
Publication type:
Article
BRCAness, SLFN11, and RB1 loss predict response to topoisomerase I inhibitors in triple-negative breast cancers.
Published in:
Science Translational Medicine, 2020, v. 12, n. 531, p. 1, doi. 10.1126/scitranslmed.aax2625
By:
- Coussy, Florence;
- El-Botty, Rania;
- Château-Joubert, Sophie;
- Dahmani, Ahmed;
- Montaudon, Elodie;
- Leboucher, Sophie;
- Morisset, Ludivine;
- Painsec, Pierre;
- Sourd, Laura;
- Huguet, Léa;
- Nemati, Fariba;
- Servely, Jean-Luc;
- Larcher, Thibaut;
- Vacher, Sophie;
- Briaux, Adrien;
- Reyes, Cécile;
- La Rosa, Philippe;
- Lucotte, Georges;
- Popova, Tatiana;
- Foidart, Pierre
Publication type:
Article
A large collection of integrated genomically characterized patient‐derived xenografts highlighting the heterogeneity of triple‐negative breast cancer.
Published in:
International Journal of Cancer, 2019, v. 145, n. 7, p. 1902, doi. 10.1002/ijc.32266
By:
- Coussy, Florence;
- Koning, Leanne;
- Lavigne, Marion;
- Bernard, Virginie;
- Ouine, Berengere;
- Boulai, Anais;
- El Botty, Rania;
- Dahmani, Ahmed;
- Montaudon, Elodie;
- Assayag, Franck;
- Morisset, Ludivine;
- Huguet, Lea;
- Sourd, Laura;
- Painsec, Pierre;
- Callens, Celine;
- Chateau‐Joubert, Sophie;
- Servely, Jean‐Luc;
- Larcher, Thibaut;
- Reyes, Cecile;
- Girard, Elodie
Publication type:
Article
Interaction between IGF2‐PI3K axis and cancer‐associated‐fibroblasts promotes anal squamous carcinogenesis.
Published in:
International Journal of Cancer, 2019, v. 145, n. 7, p. 1852, doi. 10.1002/ijc.32178
By:
- Cacheux, Wulfran;
- Lièvre, Astrid;
- Richon, Sophie;
- Vacher, Sophie;
- El Alam, Elsy;
- Briaux, Adrien;
- El Botty, Rania;
- Mariani, Pascale;
- Buecher, Bruno;
- Schnitzler, Anne;
- Barbazan, Jorge;
- Roman‐Roman, Sergio;
- Bièche, Ivan;
- Dangles‐Marie, Virginie
Publication type:
Article
Vandetanib as a potential new treatment for estrogen receptor-negative breast cancers.
Published in:
International Journal of Cancer, 2016, v. 138, n. 10, p. 2510, doi. 10.1002/ijc.29974
By:
- Hatem, Rana;
- Labiod, Dalila;
- Château‐Joubert, Sophie;
- de Plater, Ludmilla;
- El Botty, Rania;
- Vacher, Sophie;
- Bonin, Florian;
- Servely, Jean‐Luc;
- Dieras, Véronique;
- Bièche, Ivan;
- Marangoni, Elisabetta
Publication type:
Article
Acetyl-CoA carboxylase 1 controls a lipid droplet–peroxisome axis and is a vulnerability of endocrine-resistant ER<sup>+</sup> breast cancer.
Published in:
Science Translational Medicine, 2024, v. 16, n. 736, p. 1, doi. 10.1126/scitranslmed.adf9874
By:
- Bacci, Marina;
- Lorito, Nicla;
- Smiriglia, Alfredo;
- Subbiani, Angela;
- Bonechi, Francesca;
- Comito, Giuseppina;
- Morriset, Ludivine;
- El Botty, Rania;
- Benelli, Matteo;
- López-Velazco, Joanna I.;
- Caffarel, Maria M.;
- Urruticoechea, Ander;
- Sflomos, George;
- Malorni, Luca;
- Corsini, Michela;
- Ippolito, Luigi;
- Giannoni, Elisa;
- Meattini, Icro;
- Matafora, Vittoria;
- Havas, Kristina
Publication type:
Article
HRAS is a therapeutic target in malignant chemo-resistant adenomyoepithelioma of the breast.
Published in:
Journal of Hematology & Oncology, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13045-021-01158-3
By:
- Bièche, Ivan;
- Coussy, Florence;
- El‑Botty, Rania;
- Vacher, Sophie;
- Château‑Joubert, Sophie;
- Dahmani, Ahmed;
- Montaudon, Elodie;
- Reyes, Cécile;
- Gentien, David;
- Reyal, Fabien;
- Ricci, Francesco;
- Nicolas, André;
- Marchio, Caterina;
- Vincent‑Salomon, Anne;
- Laé, Marick;
- Marangoni, Elisabetta
Publication type:
Article
PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17697-1
By:
- Montaudon, Elodie;
- Nikitorowicz-Buniak, Joanna;
- Sourd, Laura;
- Morisset, Ludivine;
- El Botty, Rania;
- Huguet, Léa;
- Dahmani, Ahmed;
- Painsec, Pierre;
- Nemati, Fariba;
- Vacher, Sophie;
- Chemlali, Walid;
- Masliah-Planchon, Julien;
- Château-Joubert, Sophie;
- Rega, Camilla;
- Leal, Mariana Ferreira;
- Simigdala, Nikiana;
- Pancholi, Sunil;
- Ribas, Ricardo;
- Nicolas, André;
- Meseure, Didier
Publication type:
Article

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