Works by Eizirik DL

Results: 12

Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the american diabetes association and the European association for the study of diabetes: response to nathan et Al.

Published in:

2009

By:

Eizirik DL

Publication type:

Journal Article

Central role and mechanisms of β-cell dysfunction and death in friedreich ataxia-associated diabetes.

Published in:

2012

By:

Cnop M;
Igoillo-Esteve M;
Rai M;
Begu A;
Serroukh Y;
Depondt C;
Musuaya AE;
Marhfour I;
Ladrière L;
Moles Lopez X;
Lefkaditis D;
Moore F;
Brion JP;
Cooper JM;
Schapira AH;
Clark A;
Koeppen AH;
Marchetti P;
Pandolfo M;
Eizirik DL

Publication type:

journal article

Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis.

Published in:

2012

By:

Cunha DA;
Igoillo-Esteve M;
Gurzov EN;
Germano CM;
Naamane N;
Marhfour I;
Fukaya M;
Vanderwinden JM;
Gysemans C;
Mathieu C;
Marselli L;
Marchetti P;
Harding HP;
Ron D;
Eizirik DL;
Cnop M;
Cunha, Daniel A;
Igoillo-Esteve, Mariana;
Gurzov, Esteban N;
Germano, Carla M

Publication type:

journal article

On the immense variety and complexity of circumstances conditioning pancreatic β-cell apoptosis in type 1 diabetes.

Published in:

2012

By:

Eizirik DL;
Grieco FA;
Eizirik, Decio L;
Grieco, Fabio A

Publication type:

journal article

PTPN2, a candidate gene for type 1 diabetes, modulates pancreatic β-cell apoptosis via regulation of the BH3-only protein Bim.

Published in:

2011

By:

Santin I;
Moore F;
Colli ML;
Gurzov EN;
Marselli L;
Marchetti P;
Eizirik DL;
Santin, Izortze;
Moore, Fabrice;
Colli, Maikel L;
Gurzov, Esteban N;
Marselli, Lorella;
Marchetti, Piero;
Eizirik, Decio L

Publication type:

journal article

Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell death.

Published in:

2011

By:

Arif S;
Moore F;
Marks K;
Bouckenooghe T;
Dayan CM;
Planas R;
Vives-Pi M;
Powrie J;
Tree T;
Marchetti P;
Huang GC;
Gurzov EN;
Pujol-Borrell R;
Eizirik DL;
Peakman M;
Arif, Sefina;
Moore, Fabrice;
Marks, Katherine;
Bouckenooghe, Thomas;
Dayan, Colin M

Publication type:

journal article

Heterozygous inactivation of the Na/Ca exchanger increases glucose-induced insulin release, β-cell proliferation, and mass.

Published in:

2011

By:

Nguidjoe E;
Sokolow S;
Bigabwa S;
Pachera N;
D'Amico E;
Allagnat F;
Vanderwinden JM;
Sener A;
Manto M;
Depreter M;
Mast J;
Joanny G;
Montanya E;
Rahier J;
Cardozo AK;
Eizirik DL;
Schurmans S;
Herchuelz A;
Nguidjoe, Evrard;
Sokolow, Sophie

Publication type:

journal article

Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells.

Published in:

2010

By:

Ortis F;
Naamane N;
Flamez D;
Ladrière L;
Moore F;
Cunha DA;
Colli ML;
Thykjaer T;
Thorsen K;
Orntoft TF;
Eizirik DL;
Ortis, Fernanda;
Naamane, Najib;
Flamez, Daisy;
Ladrière, Laurence;
Moore, Fabrice;
Cunha, Daniel A;
Colli, Maikel L;
Thykjaer, Thomas;
Thorsen, Kasper

Publication type:

journal article

Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB.

Published in:

2009

By:

Cunha DA;
Ladrière L;
Ortis F;
Igoillo-Esteve M;
Gurzov EN;
Lupi R;
Marchetti P;
Eizirik DL;
Cnop M;
Cunha, Daniel A;
Ladrière, Laurence;
Ortis, Fernanda;
Igoillo-Esteve, Mariana;
Gurzov, Esteban N;
Lupi, Roberto;
Marchetti, Piero;
Eizirik, Décio L;
Cnop, Miriam

Publication type:

journal article

PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis.

Published in:

2009

By:

Moore F;
Colli ML;
Cnop M;
Esteve MI;
Cardozo AK;
Cunha DA;
Bugliani M;
Marchetti P;
Eizirik DL;
Moore, Fabrice;
Colli, Maikel L;
Cnop, Miriam;
Esteve, Mariana Igoillo;
Cardozo, Alessandra K;
Cunha, Daniel A;
Bugliani, Marco;
Marchetti, Piero;
Eizirik, Décio L

Publication type:

journal article

Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways.

Published in:

2008

By:

Dogusan Z;
García M;
Flamez D;
Alexopoulou L;
Goldman M;
Gysemans C;
Mathieu C;
Libert C;
Eizirik DL;
Rasschaert J

Publication type:

Journal Article

Disruption of the gamma-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cells.

Published in:

2005

By:

Gysemans CA;
Ladrière L;
Callewaert H;
Rasschaert J;
Flamez D;
Levy DE;
Matthys P;
Eizirik DL;
Mathieu C;
Gysemans, Conny A;
Ladrière, Laurence;
Callewaert, Hanne;
Rasschaert, Joanne;
Flamez, Daisy;
Levy, David E;
Matthys, Patrick;
Eizirik, Décio L;
Mathieu, Chantal

Publication type:

journal article