Works by Eizirik, Decio L.

Results: 146

Is there a role for locally produced interleukin-1 in the deleterious effects of high glucose or the type 2 diabetes milieu to human pancreatic islets?

Published in:

2005

By:

Welsh, Nils;
Cnop, Miriam;
Kharroubi, Ilham;
Bugliani, Marco;
Lupi, Roberto;
Marchetti, Piero;
Eizirik, Décio L.;
Eizirik, Décio L

Publication type:

journal article

Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells.

Published in:

2005

By:

Cardozo, Alessandra K.;
Ortis, Fernanda;
Storling, Joachim;
Feng, Ying-Mei;
Rasschaert, Joanne;
Tonnesen, Morten;
Van Eylen, Françoise;
Mandrup-Poulsen, Thomas;
Herchuelz, André;
Eizirik, Décio L.;
Van Eylen, Françoise;
Herchuelz, André;
Eizirik, Décio L

Publication type:

journal article

Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells.

Published in:

2003

By:

Kutlu, Burak;
Cardozo, Alessandra K.;
Darville, Martine I.;
Eizirik, Décio L.;
Kruhøffer, Mogens;
Magnusson, Nils;
Ørntoft, Torben;
Kruhøffer, Mogens;
Ørntoft, Torben;
Eizirik, Décio L

Publication type:

journal article

Molecular regulation of monocyte chemoattractant protein-1 expression in pancreatic beta-cells.

Published in:

2003

By:

Kutlu, Burak;
Darville, Martine I.;
Cardozo, Alessandra K.;
Eizirik, Décio L.;
Eizirik, Décio L

Publication type:

journal article

Preclinical evaluation of tyrosine kinase 2 inhibitors for human beta‐cell protection in type 1 diabetes.

Published in:

Diabetes, Obesity & Metabolism, 2020, v. 22, n. 10, p. 1827, doi. 10.1111/dom.14104

By:

Coomans de Brachène, Alexandra;
Castela, Angela;
Op de Beeck, Anne;
Mirmira, Raghavendra G.;
Marselli, Lorella;
Marchetti, Piero;
Masse, Craig;
Miao, Wenyan;
Leit, Silvana;
Evans‐Molina, Carmella;
Eizirik, Decio L.

Publication type:

Article

When one becomes many—Alternative splicing in β‐cell function and failure.

Published in:

Diabetes, Obesity & Metabolism, 2018, v. 20, p. 77, doi. 10.1111/dom.13388

By:

Alvelos, Maria Inês;
Juan‐Mateu, Jonàs;
Colli, Maikel Luis;
Turatsinze, Jean‐Valéry;
Eizirik, Décio L.

Publication type:

Article

Distinct gene expression pathways in islets from individuals with short‐ and long‐duration type 1 diabetes.

Published in:

Diabetes, Obesity & Metabolism, 2018, v. 20, n. 8, p. 1859, doi. 10.1111/dom.13298

By:

Mastracci, Teresa L.;
Turatsinze, Jean‐Valery;
Book, Benita K.;
Restrepo, Ivan A.;
Pugia, Michael J.;
Wiebke, Eric A.;
Pescovitz, Mark D.;
Eizirik, Decio L.;
Mirmira, Raghavendra G.

Publication type:

Article

Coxsackievirus B Tailors the Unfolded Protein Response to Favour Viral Amplification in Pancreatic β Cells.

Published in:

Journal of Innate Immunity, 2019, v. 11, n. 4, p. 375, doi. 10.1159/000496034

By:

Colli, Maikel L.;
Paula, Flavia M.;
Marselli, Lorella;
Marchetti, Piero;
Roivainen, Merja;
Eizirik, Decio L.;
Op de beeck, Anne

Publication type:

Article

The Pancreatic ß-cell Response to Secretory Demands and Adaption to Stress.

Published in:

Endocrinology, 2021, v. 162, n. 11, p. 1, doi. 10.1210/endocr/bqab173

By:

Kalwat, Michael A;
Scheuner, Donalyn;
Rodrigues-dos-Santos, Karina;
Eizirik, Decio L;
Cobb, Melanie H

Publication type:

Article

The RNA-binding profile of the splicing factor SRSF6 in immortalized human pancreatic β-cells.

Published in:

Life Science Alliance, 2021, v. 4, n. 3, p. 1, doi. 10.26508/lsa.202000825

By:

Alvelos, Maria Inês;
Brüggemann, Mirko;
Sutandy, F. X. Reymond;
Juan-Mateu, Jonàs;
Colli, Maikel Luis;
Busch, Anke;
Lopes, Miguel;
Castela, Ângela;
Aartsma-Rus, Annemieke;
König, Julian;
Zarnack, Kathi;
Eizirik, Décio L.

Publication type:

Article

Pro-Inflammatory Cytokines Promote the Transcription of Circular RNAs in Human Pancreatic β Cells.

Published in:

Non-Coding RNA, 2022, v. 8, n. 5, p. 69, doi. 10.3390/ncrna8050069

By:

Kaur, Simranjeet;
Frørup, Caroline;
Mirza, Aashiq H.;
Fløyel, Tina;
Yarani, Reza;
Colli, Maikel L.;
Johannesen, Jesper;
Størling, Joachim;
Eizirik, Decio L.;
Pociot, Flemming

Publication type:

Article

The Protective Action of Metformin against Pro-Inflammatory Cytokine-Induced Human Islet Cell Damage and the Mechanisms Involved.

Published in:

Cells (2073-4409), 2022, v. 11, n. 15, p. 2465, doi. 10.3390/cells11152465

By:

Giusti, Laura;
Tesi, Marta;
Ciregia, Federica;
Marselli, Lorella;
Zallocco, Lorenzo;
Suleiman, Mara;
De Luca, Carmela;
Del Guerra, Silvia;
Zuccarini, Mariachiara;
Trerotola, Marco;
Eizirik, Decio L.;
Cnop, Miriam;
Mazzoni, Maria R.;
Marchetti, Piero;
Lucacchini, Antonio;
Ronci, Maurizio

Publication type:

Article

T1DBase: integration and presentation of complex data for type 1 diabetes research.

Published in:

Nucleic Acids Research, 2007, v. 35, p. d742, doi. 10.1093/nar/gkl933

By:

Hulbert, Erin M.;
Smink, Luc J.;
Adlem, Ellen C.;
Allen, James E.;
Burdick, David B.;
Burren, Oliver S.;
Cavnor, Christopher C.;
Dolman, Geoffrey E.;
Flamez, Daisy;
Friery, Karen F.;
Healy, Barry C.;
Killcoyne, Sarah A.;
Kutlu, Burak;
Schuilenburg, Helen;
Walker, Neil M.;
Mychaleckyj, Josyf;
Eizirik, Decio L.;
Wicker, Linda S.;
Todd, John A.;
Goodman, Nathan

Publication type:

Article

T1DBase, a community web-based resource for type 1 diabetes research.

Published in:

Nucleic Acids Research, 2005, v. 33, n. suppl 1, p. d544

By:

Smink, Luc J.;
Helton, Erin M.;
Healy, Barry C.;
Cavnor, Christopher C.;
Lam, Alex C.;
Flamez, Daisy;
Burren, Oliver S.;
Wang, Yang;
Dolman, Geoffrey E.;
Burdick, David B.;
Everett, Vincent H.;
Glusman, Gustavo;
Laneri, Davide;
Rowen, Lee;
Schuilenburg, Helen;
Walker, Neil M.;
Mychaleckyj, Josyf;
Wicker, Linda S.;
Eizirik, Decio L.;
Todd, John A.

Publication type:

Article

β‐Cell gene expression stress signatures in types 1 and 2 diabetes.

Published in:

Journal of Diabetes, 2024, v. 16, n. 11, p. 1, doi. 10.1111/1753-0407.70026

By:

Yi, Xiaoyan;
Eizirik, Decio L.

Publication type:

Article

Peptides Derived From Insulin Granule Proteins Are Targeted by CD8+ T Cells Across MHC Class I Restrictions in Humans and NOD Mice.

Published in:

2020

By:

Azoury, Marie Eliane;
Tarayrah, Mahmoud;
Afonso, Georgia;
Pais, Aurore;
Colli, Maikel L.;
Maillard, Claire;
Lavaud, Cassandra;
Alexandre-Heymann, Laure;
Gonzalez-Duque, Sergio;
Verdier, Yann;
Vinh, Joelle;
Pinto, Sheena;
Buus, Soren;
Dubois-Laforgue, Danièle;
Larger, Etienne;
Beressi, Jean-Paul;
Bruno, Graziella;
Eizirik, Decio L.;
You, Sylvaine;
Mallone, Roberto

Publication type:

journal article

tRNA Methyltransferase Homolog Gene TRMT10A Mutation in Young Onset Diabetes and Primary Microcephaly in Humans.

Published in:

PLoS Genetics, 2013, v. 9, n. 10, p. 1, doi. 10.1371/journal.pgen.1003888

By:

Igoillo-Esteve, Mariana;
Genin, Anne;
Lambert, Nelle;
Désir, Julie;
Pirson, Isabelle;
Abdulkarim, Baroj;
Simonis, Nicolas;
Drielsma, Anais;
Marselli, Lorella;
Marchetti, Piero;
Vanderhaeghen, Pierre;
Eizirik, Décio L.;
Wuyts, Wim;
Julier, Cécile;
Chakera, Ali J.;
Ellard, Sian;
Hattersley, Andrew T.;
Abramowicz, Marc;
Cnop, Miriam

Publication type:

Article

GLIS3, a Susceptibility Gene for Type 1 and Type 2 Diabetes, Modulates Pancreatic Beta Cell Apoptosis via Regulation of a Splice Variant of the BH3-Only Protein Bim

Published in:

PLoS Genetics, 2013, v. 9, n. 5, p. 1, doi. 10.1371/journal.pgen.1003532

By:

Nogueira, Tatiane C.;
Paula, Flavia M.;
Villate, Olatz;
Colli, Maikel L.;
Moura, Rodrigo F.;
Cunha, Daniel A.;
Marselli, Lorella;
Marchetti, Piero;
Cnop, Miriam;
Julier, Cécile;
Eizirik, Decio L.

Publication type:

Article

The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro-Inflammatory Cytokines.

Published in:

PLoS Genetics, 2012, v. 8, n. 3, p. 1, doi. 10.1371/journal.pgen.1002552

By:

Eizirik, Décio L.;
Sammeth, Michael;
Bouckenooghe, Thomas;
Bottu, Guy;
Sisino, Giorgia;
Igoillo-Esteve, Mariana;
Ortis, Fernanda;
Santin, Izortze;
Colli, Maikel L.;
Barthson, Jenny;
Bouwens, Luc;
Hughes, Linda;
Gregory, Lorna;
Lunter, Gerton;
Marselli, Lorella;
Marchetti, Piero;
McCarthy, Mark I.;
Cnop, Miriam

Publication type:

Article

BCL-XL Overexpression Protects Pancreatic β-Cells against Cytokine- and Palmitate-Induced Apoptosis.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5657, doi. 10.3390/ijms24065657

By:

Perez-Serna, Atenea A.;
Dos Santos, Reinaldo S.;
Ripoll, Cristina;
Nadal, Angel;
Eizirik, Decio L.;
Marroqui, Laura

Publication type:

Article

The Role of Beta Cell Recovery in Type 2 Diabetes Remission.

Published in:

2022

By:

Suleiman, Mara;
Marselli, Lorella;
Cnop, Miriam;
Eizirik, Decio L.;
De Luca, Carmela;
Femia, Francesca R.;
Tesi, Marta;
Del Guerra, Silvia;
Marchetti, Piero

Publication type:

Literature Review

Beta Cell Imaging—From Pre-Clinical Validation to First in Man Testing.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 19, p. 7274, doi. 10.3390/ijms21197274

By:

Demine, Stephane;
Schulte, Michael L.;
Territo, Paul R.;
Eizirik, Decio L.

Publication type:

Article

Strain Differences Determine the Suitability of Animal Models for Noninvasive In Vivo Beta Cell Mass Determination with Radiolabeled Exendin.

Published in:

2016

By:

Willekens, Stefanie;
Joosten, Lieke;
Boerman, Otto;
Balhuizen, Alexander;
Eizirik, Decio;
Gotthardt, Martin;
Brom, Maarten;
Willekens, Stefanie M A;
Boerman, Otto C;
Eizirik, Decio L

Publication type:

journal article

A novel inhibitor of inducible NOS dimerization protects against cytokine-induced rat beta cell dysfunction.

Published in:

2018

By:

Zhong, Linlin;
Tran, Tuan;
Baguley, Tyler D.;
Lee, Sang Jun;
Henke, Adam;
To, Andrew;
Li, Sijia;
Yu, Shan;
Grieco, Fabio A.;
Roland, Jason;
Schultz, Peter G.;
Eizirik, Decio L.;
Rogers, Nikki;
Chartterjee, Arnab K.;
Tremblay, Matthew S.;
Shen, Weijun

Publication type:

journal article

Myo9b mutations are associated with altered dendritic cell functions and increased susceptibility to autoimmune diabetes onset.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41534-w

By:

Zhang, Jing;
Zou, Yuan;
Chen, Longmin;
Sun, Fei;
Xu, Qianqian;
Zhou, Qing;
Wang, Yi;
Luo, Xi;
Wang, Na;
Li, Yang;
Zhang, Shu;
Xiong, Fei;
Yang, Ping;
Liu, Shiwei;
Yang, Tao;
Weng, Jianping;
Eizirik, Décio L.;
Yan, Jinhua;
Zhou, Zhiguang;
Wang, Cong-Yi

Publication type:

Article

Restoration of the Unfolded Protein Response in Pancreatic β Cells Protects Mice Against Type 1 Diabetes.

Published in:

Science Translational Medicine, 2013, v. 5, n. 211, p. 1, doi. 10.1126/scitranslmed.3006534

By:

Engin, Feyza;
Yermalovich, Alena;
Truc Nguyen;
Hummasti, Sarah;
Wenxian Fu;
Eizirik, Decio L.;
Mathis, Diane;
Hotamisligil, Gökhan S.

Publication type:

Article

The role of proteomics in assessing beta-cell dysfunction and death in type 1 diabetes.

Published in:

Expert Review of Proteomics, 2019, v. 16, n. 7, p. 569, doi. 10.1080/14789450.2019.1634548

By:

Nakayasu, Ernesto S.;
Qian, Wei-Jun;
Evans-Molina, Carmella;
Mirmira, Raghavendra G.;
Eizirik, Decio L.;
Metz, Thomas O.

Publication type:

Article

Mechanisms of Coxsackievirus-Induced Damage to Human Pancreatic β-Cells.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2000, v. 85, n. 1, p. 432, doi. 10.1210/jcem.85.1.6306

By:

ROIVAINEN, MERJA;
RASILAINEN, SUVI;
YLIPAASTO, PETRI;
NISSINEN, RIIKKA;
USTINOV, JARKKO;
BOUWENS, LUC;
EIZIRIK, DÉCIO L.;
HOVI, TAPANI;
OTONKOSKI, TIMO

Publication type:

Article

Mechanisms of Defective Glucose-Induced Insulin Release in Human Pancreatic Islets Transplanted to Diabetic Nude Mice.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1997, v. 82, n. 8, p. 2660, doi. 10.1210/jcem.82.8.4150

By:

EIZIRIK, DÉCIO L.;
JANSSON, LEIF;
FLODSTRÖM, MALIN;
HELLERSTRÖM, CLAES;
ANDERSSON, ARNE

Publication type:

Article

Genetic regulation of RNA splicing in human pancreatic islets.

Published in:

Genome Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s13059-022-02757-0

By:

Atla, Goutham;
Bonàs-Guarch, Silvia;
Cuenca-Ardura, Mirabai;
Beucher, Anthony;
Crouch, Daniel J. M.;
Garcia-Hurtado, Javier;
Moran, Ignasi;
the T2DSystems Consortium;
Cnop, Miriam;
Eliasson, Lena;
Esguerra, Jonathan Lou S.;
Eizirik, Décio L.;
Groop, Leif;
Jensen, Thomas S.;
Hansen, Torben;
Marchetti, Piero;
Mercader, Josep M.;
Mulder, Hindrik;
Stabile-Barnett, Chris R.;
Thirion, Christian

Publication type:

Article

Enhanced Signaling Downstream of Ribonucleic Acid-Activated Protein Kinase-Like Endoplasmic Reticulum Kinase Potentiates Lipotoxic Endoplasmic Reticulum Stress in Human Islets.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2010, v. 95, n. 3, p. 1442, doi. 10.1210/jc.2009-2322

By:

Ladrière, Laurence;
Igoillo-Esteve, Mariana;
Cunha, Daniel A.;
Brion, Jean-Pierre;
Bugliani, Marco;
Marchetti, Piero;
L. Eizirik, Décio;
Cnop, Miriam

Publication type:

Article

Regulation of β-cell death by ADP-ribosylhydrolase ARH3 via lipid signaling in insulitis.

Published in:

Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-023-01437-1

By:

Sarkar, Soumyadeep;
Deiter, Cailin;
Kyle, Jennifer E.;
Guney, Michelle A.;
Sarbaugh, Dylan;
Yin, Ruichuan;
Li, Xiangtang;
Cui, Yi;
Ramos-Rodriguez, Mireia;
Nicora, Carrie D.;
Syed, Farooq;
Juan-Mateu, Jonas;
Muralidharan, Charanya;
Pasquali, Lorenzo;
Evans-Molina, Carmella;
Eizirik, Decio L.;
Webb-Robertson, Bobbie-Jo M.;
Burnum-Johnson, Kristin;
Orr, Galya;
Laskin, Julia

Publication type:

Article

Regulation of β-cell death by ADP-ribosylhydrolase ARH3 via lipid signaling in insulitis.

Published in:

Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-023-01437-1

By:

Sarkar, Soumyadeep;
Deiter, Cailin;
Kyle, Jennifer E.;
Guney, Michelle A.;
Sarbaugh, Dylan;
Yin, Ruichuan;
Li, Xiangtang;
Cui, Yi;
Ramos-Rodriguez, Mireia;
Nicora, Carrie D.;
Syed, Farooq;
Juan-Mateu, Jonas;
Muralidharan, Charanya;
Pasquali, Lorenzo;
Evans-Molina, Carmella;
Eizirik, Decio L.;
Webb-Robertson, Bobbie-Jo M.;
Burnum-Johnson, Kristin;
Orr, Galya;
Laskin, Julia

Publication type:

Article

Exposure to the Viral By-Product dsRNA or Coxsackievirus B5 Triggers Pancreatic Beta Cell Apoptosis via a Bim / Mcl-1 Imbalance.

Published in:

PLoS Pathogens, 2011, v. 7, n. 9, p. 1, doi. 10.1371/journal.ppat.1002267

By:

Colli, Maikel L.;
Nogueira, Tatiane C.;
Allagnat, Florent;
Cunha, Daniel A.;
Gurzov, Esteban N.;
Cardozo, Alessandra K.;
Roivainen, Merja;
de beeck, Anne Op;
Eizirik, Decio L.

Publication type:

Article

Exercise-induced meteorin-like protein protects human pancreatic beta cells from cytokine-induced apoptosis.

Published in:

Diabetologia, 2025, v. 68, n. 7, p. 1524, doi. 10.1007/s00125-025-06426-2

By:

Costa-Junior, José Maria;
Coomans de Brachène, Alexandra;
Musuaya, Anyïshai E.;
Zimath, Priscila L.;
Martin-Vazquez, Eugenia;
Oliveira, Junior G.;
Carpentier, Julie;
Faoro, Vitalie;
Klass, Malgorzata;
Cnop, Miriam;
Eizirik, Decio L.

Publication type:

Article

Beta cell extracellular vesicle PD-L1 as a novel regulator of CD8+ T cell activity and biomarker during the evolution of type 1 diabetes.

Published in:

Diabetologia, 2025, v. 68, n. 2, p. 382, doi. 10.1007/s00125-024-06313-2

By:

Rao, Chaitra;
Cater, Daniel T.;
Roy, Saptarshi;
Xu, Jerry;
De Oliveira, Andre G.;
Evans-Molina, Carmella;
Piganelli, Jon D.;
Eizirik, Decio L.;
Mirmira, Raghavendra G.;
Sims, Emily K.

Publication type:

Article

Comment on the role of interferons in the pathology of beta cell destruction in type 1 diabetes. Reply to Lenzen S [letter].

Published in:

2024

By:

Eizirik, Decio L.;
Zimath, Priscila L.;
Yi, Xiaoyan;
Roca Rivada, Arturo;
Richardson, Sarah J.

Publication type:

Letter

Inhibition of the type 1 diabetes candidate gene PTPN2 aggravates TNF-α-induced human beta cell dysfunction and death.

Published in:

Diabetologia, 2023, v. 66, n. 8, p. 1544, doi. 10.1007/s00125-023-05908-5

By:

Roca-Rivada, Arturo;
Marín-Cañas, Sandra;
Colli, Maikel L.;
Vinci, Chiara;
Sawatani, Toshiaki;
Marselli, Lorella;
Cnop, Miriam;
Marchetti, Piero;
Eizirik, Decio L.

Publication type:

Article

The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes.

Published in:

Diabetologia, 2023, v. 66, n. 7, p. 1273, doi. 10.1007/s00125-023-05912-9

By:

Huerta-Chagoya, Alicia;
Schroeder, Philip;
Mandla, Ravi;
Deutsch, Aaron J.;
Zhu, Wanying;
Petty, Lauren;
Yi, Xiaoyan;
Cole, Joanne B.;
Udler, Miriam S.;
Dornbos, Peter;
Porneala, Bianca;
DiCorpo, Daniel;
Liu, Ching-Ti;
Li, Josephine H.;
Szczerbiński, Lukasz;
Kaur, Varinderpal;
Kim, Joohyun;
Lu, Yingchang;
Martin, Alicia;
Eizirik, Decio L.

Publication type:

Article

Exercise as a non-pharmacological intervention to protect pancreatic beta cells in individuals with type 1 and type 2 diabetes.

Published in:

Diabetologia, 2023, v. 66, n. 3, p. 450, doi. 10.1007/s00125-022-05837-9

By:

Coomans de Brachène, Alexandra;
Scoubeau, Corentin;
Musuaya, Anyïshai E.;
Costa-Junior, Jose Maria;
Castela, Angela;
Carpentier, Julie;
Faoro, Vitalie;
Klass, Malgorzata;
Cnop, Miriam;
Eizirik, Decio L.

Publication type:

Article

Presumption of innocence for beta cells: why are they vulnerable autoimmune targets in type 1 diabetes?

Published in:

Diabetologia, 2020, v. 63, n. 10, p. 1999, doi. 10.1007/s00125-020-05176-7

By:

Mallone, Roberto;
Eizirik, Decio L.

Publication type:

Article

Extracellular HMGB1 exacerbates autoimmune progression and recurrence of type 1 diabetes by impairing regulatory T cell stability.

Published in:

Diabetologia, 2020, v. 63, n. 5, p. 987, doi. 10.1007/s00125-020-05105-8

By:

Zhang, Jing;
Chen, Longmin;
Wang, Faxi;
Zou, Yuan;
Li, Jingyi;
Luo, Jiahui;
Khan, Faheem;
Sun, Fei;
Li, Yang;
Liu, Jing;
Chen, Zhishui;
Zhang, Shu;
Xiong, Fei;
Yu, Qilin;
Li, Jinxiu;
Huang, Kun;
Adam, Bao-Ling;
Zhou, Zhiguang;
Eizirik, Decio L.;
Yang, Ping

Publication type:

Article

A nanobody-based nuclear imaging tracer targeting dipeptidyl peptidase 6 to determine the mass of human beta cell grafts in mice.

Published in:

Diabetologia, 2020, v. 63, n. 4, p. 825, doi. 10.1007/s00125-019-05068-5

By:

Demine, Stéphane;
Garcia Ribeiro, Rita;
Thevenet, Julien;
Marselli, Lorella;
Marchetti, Piero;
Pattou, François;
Kerr-Conte, Julie;
Devoogdt, Nick;
Eizirik, Decio L.

Publication type:

Article

Fostering improved human islet research: a European perspective.

Published in:

2019

By:

Marchetti, Piero;
Schulte, Anke M.;
Marselli, Lorella;
Schoniger, Eyke;
Bugliani, Marco;
Kramer, Werner;
Overbergh, Lut;
Ullrich, Susanne;
Gloyn, Anna L.;
Ibberson, Mark;
Rutter, Guy;
Froguel, Philippe;
Groop, Leif;
McCarthy, Mark I.;
Dotta, Francesco;
Scharfmann, Raphael;
Magnan, Christophe;
Eizirik, Decio L.;
Mathieu, Chantal;
Cnop, Miriam

Publication type:

Letter

DEXI, a candidate gene for type 1 diabetes, modulates rat and human pancreatic beta cell inflammation via regulation of the type I IFN/STAT signalling pathway.

Published in:

Diabetologia, 2019, v. 62, n. 3, p. 459, doi. 10.1007/s00125-018-4782-0

By:

Dos Santos, Reinaldo S.;
Marroqui, Laura;
Velayos, Teresa;
Olazagoitia-Garmendia, Ane;
Jauregi-Miguel, Amaia;
Castellanos-Rubio, Ainara;
Eizirik, Decio L.;
Castaño, Luis;
Santin, Izortze

Publication type:

Article

Detection and quantification of beta cells by PET imaging: why clinical implementation has never been closer.

Published in:

Diabetologia, 2018, v. 61, n. 12, p. 2516, doi. 10.1007/s00125-018-4745-5

By:

Gotthardt, Martin;
Eizirik, Decio L.;
Aanstoot, Henk-Jan;
Korsgren, Olle;
Mul, Dick;
Martin, Frank;
Boss, Marti;
Jansen, Tom J. P.;
van Lith, Sanne A. M.;
Buitinga, Mijke;
Eriksson, Olof;
Cnop, Miriam;
Brom, Maarten

Publication type:

Article

Unexpected subcellular distribution of a specific isoform of the Coxsackie and adenovirus receptor, CAR-SIV, in human pancreatic beta cells.

Published in:

Diabetologia, 2018, v. 61, n. 11, p. 2344, doi. 10.1007/s00125-018-4704-1

By:

Ifie, Eseoghene;
Russell, Mark A.;
Dhayal, Shalinee;
Leete, Pia;
Sebastiani, Guido;
Nigi, Laura;
Dotta, Francesco;
Marjomäki, Varpu;
Eizirik, Decio L.;
Morgan, Noel G.;
Richardson, Sarah J.

Publication type:

Article

Biomarkers of islet beta cell stress and death in type 1 diabetes.

Published in:

Diabetologia, 2018, v. 61, n. 11, p. 2259, doi. 10.1007/s00125-018-4712-1

By:

Sims, Emily K.;
Evans-Molina, Carmella;
Tersey, Sarah A.;
Eizirik, Decio L.;
Mirmira, Raghavendra G.

Publication type:

Article

IFN-α induces a preferential long-lasting expression of MHC class I in human pancreatic beta cells.

Published in:

Diabetologia, 2018, v. 61, n. 3, p. 636, doi. 10.1007/s00125-017-4536-4

By:

Coomans de Brachène, Alexandra;
Dos Santos, Reinaldo S.;
Marroqui, Laura;
Colli, Maikel L.;
Marselli, Lorella;
Mirmira, Raghavendra G.;
Marchetti, Piero;
Eizirik, Decio L.

Publication type:

Article

Pro-Inflammatory Cytokines Induce Insulin and Glucagon Double Positive Human Islet Cells That Are Resistant to Apoptosis.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 2, p. 320, doi. 10.3390/biom11020320

By:

Tesi, Marta;
Bugliani, Marco;
Ferri, Gianmarco;
Suleiman, Mara;
De Luca, Carmela;
Bosi, Emanuele;
Masini, Matilde;
De Tata, Vincenzo;
Gysemans, Conny;
Cardarelli, Francesco;
Cnop, Miriam;
Eizirik, Decio L.;
Marchetti, Piero;
Marselli, Lorella

Publication type:

Article