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Interferon-γ potentiates endoplasmic reticulum stress-induced death by reducing pancreatic beta cell defence mechanisms.
- Published in:
- Diabetologia, 2006, v. 49, n. 6, p. 1229, doi. 10.1007/s00125-006-0214-7
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- Publication type:
- Article
Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor κB-mediated gene expression in insulin-producing INS-1E cells.
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- Diabetologia, 2005, v. 48, n. 12, p. 2582, doi. 10.1007/s00125-005-0039-9
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- Publication type:
- Article
High glucose and hydrogen peroxide increase c-Myc and haeme-oxygenase 1 mRNA levels in rat pancreatic islets without activating NFκB.
- Published in:
- 2005
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- Publication type:
- Correction Notice
Global profiling of coxsackievirus- and cytokine-induced gene expression in human pancreatic islets.
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- Diabetologia, 2005, v. 48, n. 8, p. 1510, doi. 10.1007/s00125-005-1839-7
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- Publication type:
- Article
High glucose and hydrogen peroxide increase c-Myc and haeme-oxygenase 1 mRNA levels in rat pancreatic islets without activating NF?B.
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- Diabetologia, 2005, v. 48, n. 3, p. 496, doi. 10.1007/s00125-004-1664-4
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- Publication type:
- Article
Global profiling of double stranded RNA- and IFN-γ-induced genes in rat pancreatic beta cells.
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- Diabetologia, 2003, v. 46, n. 12, p. 1641, doi. 10.1007/s00125-003-1245-y
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- Publication type:
- Article
IL-1β and IFN-γ induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice A.K. Cardozo et al.: Chemokine expression by pancreatic islets.
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- Diabetologia, 2003, v. 46, n. 2, p. 255, doi. 10.1007/s00125-002-1017-0
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- Article
Erratum: Diabetologia (2001) 44: 2115–2133.
- Published in:
- 2002
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- Publication type:
- Erratum
A choice of death – the signal-transduction of immune-mediated beta-cell apoptosis.
- Published in:
- Diabetologia, 2001, v. 44, n. 12, p. 2115, doi. 10.1007/s001250100021
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- Publication type:
- Article
Dual role of interferon-γ signalling pathway in sensitivity of pancreatic beta cells to immune destruction.
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- Diabetologia, 2001, v. 44, n. 5, p. 567, doi. 10.1007/s001250051662
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- Publication type:
- Article
Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1β-exposed human and rat islet cells.
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- Diabetologia, 2001, v. 44, n. 3, p. 325, doi. 10.1007/s001250051622
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- Publication type:
- Article
Nitric Oxide Synthase And Antimicrobial Armature Of Human Macrophages.
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- Journal of Infectious Diseases, 1994, v. 170, n. 3, p. 744
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- Publication type:
- Article
Candidate genes for type 1 diabetes modulate pancreatic islet inflammation and β-cell apoptosis.
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- Diabetes, Obesity & Metabolism, 2013, v. 15, p. 71, doi. 10.1111/dom.12162
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- Publication type:
- Article
Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation.
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- Oncogene, 2012, v. 31, n. 13, p. 1723, doi. 10.1038/onc.2011.353
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- Publication type:
- Article
Reduced diabetogenic effect of streptozotocin in rats previously adapted to a high-protein, carbohydrate-free diet.
- Published in:
- 1984
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- Publication type:
- journal article
IL-1 receptor antagonist inhibits recurrence of disease after syngeneic pancreatic islet transplantation to spontaneously diabetic non-obese diabetic (NOD) mice.
- Published in:
- Clinical & Experimental Immunology, 1997, v. 108, n. 2, p. 314, doi. 10.1046/j.1365-2249.1997.3771275.x
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- Publication type:
- Article
Absence of autoantibodies against glutamate decarboxylase (GAD) in the non-obese diabetic (NOD) mouse and low expression of the enzyme in mouse islets.
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- Clinical & Experimental Immunology, 1994, v. 96, n. 1, p. 129
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- Publication type:
- Article
JunB protects β-cells from lipotoxicity via the XBP1-AKT pathway.
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- Cell Death & Differentiation, 2014, v. 21, n. 8, p. 1313, doi. 10.1038/cdd.2014.53
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- Publication type:
- Article
C/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in β-cells.
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- Cell Death & Differentiation, 2012, v. 19, n. 11, p. 1836, doi. 10.1038/cdd.2012.67
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- Publication type:
- Article
Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosis.
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- Cell Death & Differentiation, 2011, v. 18, n. 2, p. 328, doi. 10.1038/cdd.2010.105
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- Publication type:
- Article
Signaling by IL-1β+IFN-γ and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic β-cell apoptosis.
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- Cell Death & Differentiation, 2009, v. 16, n. 11, p. 1539, doi. 10.1038/cdd.2009.99
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- Publication type:
- Article
Modulation of Autophagy Influences the Function and Survival of Human Pancreatic Beta Cells Under Endoplasmic Reticulum Stress Conditions and in Type 2 Diabetes.
- Published in:
- Frontiers in Endocrinology, 2019, p. N.PAG, doi. 10.3389/fendo.2019.00052
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- Publication type:
- Article
Endoplasmic reticulum stress sensitizes pancreatic beta cells to interleukin-1β-induced apoptosis via Bim/A1 imbalance.
- Published in:
- Cell Death & Disease, 2013, v. 4, n. 7, p. 1, doi. 10.1038/cddis.2013.236
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- Publication type:
- Article
Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis.
- Published in:
- 2001
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- Publication type:
- journal article
Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation.
- Published in:
- 2001
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- Publication type:
- journal article
Cytokine induction of Fas gene expression in insulin-producing cells requires the transcription factors NF-kappaB and C/EBP.
- Published in:
- 2001
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- Publication type:
- journal article
Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays.
- Published in:
- 2001
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- Publication type:
- journal article
beta-cell apoptosis and defense mechanisms: lessons from type 1 diabetes.
- Published in:
- 2001
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- Publication type:
- journal article
Molecular regulation of Fas expression in beta-cells.
- Published in:
- 2001
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- Publication type:
- journal article
Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-).
- Published in:
- 2000
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- Publication type:
- journal article
Interleukin-1beta-induced alteration in a beta-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis.
- Published in:
- 2000
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- Publication type:
- journal article
Contribution of ductal cells to cytokine responses by human pancreatic islets.
- Published in:
- 1999
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- Publication type:
- journal article
Efficient gene transfer to dispersed human pancreatic islet cells in vitro using adenovirus-polylysine/DNA complexes or polycationic liposomes.
- Published in:
- 1996
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- Publication type:
- journal article
Treatment with an interleukin-1 receptor antagonist protein prolongs mouse islet allograft survival.
- Published in:
- 1993
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- Publication type:
- journal article
Repair of pancreatic beta-cells. A relevant phenomenon in early IDDM?
- Published in:
- 1993
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- Publication type:
- journal article
Genotoxic agents increase expression of growth arrest and DNA damage--inducible genes gadd 153 and gadd 45 in rat pancreatic islets.
- Published in:
- 1993
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- Publication type:
- journal article
Liposomal delivery of purified heat shock protein hsp70 into rat pancreatic islets as protection against interleukin 1 beta-induced impaired beta-cell function.
- Published in:
- 1991
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- Publication type:
- journal article
Functional characteristics of rat pancreatic islets maintained in culture after exposure to human interleukin 1.
- Published in:
- 1988
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- Publication type:
- journal article