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DARPP‐32 genomic fragments drive Cre expression in postnatal striatum.
- Published in:
- Genesis: The Journal of Genetics & Development, 2005, v. 42, n. 1, p. 37, doi. 10.1002/gene.20118
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- Publication type:
- Article
Physiologically generated presenilin 1 lacking exon 8 fails to rescue brain PS1−/− phenotype and forms complexes with wildtype PS1 and nicastrin.
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- Scientific Reports, 2015, p. 17042, doi. 10.1038/srep17042
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- Publication type:
- Article
Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces β-Amyloid Load in Males and Females.
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- Cells (2073-4409), 2022, v. 11, n. 23, p. 3880, doi. 10.3390/cells11233880
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- Article
Intranasal Peptide Therapeutics: A Promising Avenue for Overcoming the Challenges of Traditional CNS Drug Development.
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- Cells (2073-4409), 2022, v. 11, n. 22, p. 3629, doi. 10.3390/cells11223629
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- Publication type:
- Article
Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice.
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- Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1400447
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- Publication type:
- Article
Protein Sortin g Motifs in the Cytoplasmic Tail of SorCSl Control Generation of Alzheimer's Amyloid-ß Peptide.
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- Journal of Neuroscience, 2013, v. 33, n. 16, p. 7099, doi. 10.1523/JNEUROSCI.5270-12.2013
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- Publication type:
- Article
Egr-1 Induces DARPP-32 Expression in Striatal Medium Spiny Neurons via a Conserved Intragenic Element.
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- Journal of Neuroscience, 2012, v. 32, n. 20, p. 6808, doi. 10.1523/JNEUROSCI.5448-11.2012
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- Publication type:
- Article
Diabetes-Associated SorCS1 Regulates Alzheimer's Amyloid-β Metabolism: Evidence for Involvement of SorL1 and the Retromer Complex.
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- Journal of Neuroscience, 2010, v. 30, n. 39, p. 13110, doi. 10.1523/JNEUROSCI.3872-10.2010
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- Publication type:
- Article
Group II Metabotropic Glutamate Receptor Stimulation Triggers Production and Release of Alzheimer's Amyloid β<sub>42</sub> from Isolated Intact Nerve Terminals.
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- Journal of Neuroscience, 2010, v. 30, n. 11, p. 3870, doi. 10.1523/JNEUROSCI.4717-09.2010
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- Publication type:
- Article
Trk: A Neuromodulator of Age-Specific Behavioral and Neurochemical Responses to Cocaine in Mice.
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- Journal of Neuroscience, 2008, v. 28, n. 5, p. 1198, doi. 10.1523/JNEUROSCI.0988-07.2008
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- Publication type:
- Article
Neonatal Opioid Withdrawal Syndrome in Mice: Acute Molecular and Long‐Term Behavioral Consequences.
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- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R4002
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- Publication type:
- Article
Phosphatidylinositide 3-kinase and protein kinase C zeta mediate retinoic acid induction of DARPP-32 in medium size spiny neurons in vitro.
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- Journal of Neurochemistry, 2008, v. 106, n. 2, p. 917, doi. 10.1111/j.1471-4159.2008.05475.x
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- Publication type:
- Article
Alzheimer’s presenilin 1 modulates sorting of APP and its carboxyl-terminal fragments in cerebral neurons in vivo.
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- Journal of Neurochemistry, 2007, v. 102, n. 3, p. 619, doi. 10.1111/j.1471-4159.2007.04587.x
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- Publication type:
- Article
In vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons.
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- Human Molecular Genetics, 2011, v. 20, n. 6, p. 1049, doi. 10.1093/hmg/ddq548
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- Publication type:
- Article
Neocortical expression of mutant huntingtin is not required for alterations in striatal gene expression or motor dysfunction in a transgenic mouse.
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- Human Molecular Genetics, 2008, v. 17, n. 20, p. 3095, doi. 10.1093/hmg/ddn206
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- Publication type:
- Article
Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome.
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- Addiction, 2011, v. 106, n. 3, p. 574, doi. 10.1111/j.1360-0443.2010.03170.x
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- Publication type:
- Article
miR155 regulation of behavior, neuropathology, and cortical transcriptomics in Alzheimer's disease.
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- Acta Neuropathologica, 2020, v. 140, n. 3, p. 295, doi. 10.1007/s00401-020-02185-z
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- Publication type:
- Article
Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer's APP/PSEN1 mice by gene targeting of diabetes/Alzheimer's-related Sorcs1.
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- Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0282-y
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- Publication type:
- Article
Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation.
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- eLife, 2021, p. 1, doi. 10.7554/eLife.65979
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- Publication type:
- Article
Behavioral and transcriptome alterations in male and female mice with postnatal deletion of TrkB in dorsal striatal medium spiny neurons.
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- Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 2, doi. 10.1186/1750-1326-8-47
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- Publication type:
- Article
Protein kinase C and rho activated coiled coil protein kinase 2 (ROCK2) modulate Alzheimer's APP metabolism and phosphorylation of the Vps10-domain protein, SorL1.
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- Molecular Neurodegeneration, 2011, v. 6, n. 1, p. 62, doi. 10.1186/1750-1326-5-62
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- Publication type:
- Article
Mutations in GNAL cause primary torsion dystonia.
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- Nature Genetics, 2013, v. 45, n. 1, p. 88, doi. 10.1038/ng.2496
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- Publication type:
- Article
Mutations in the THAP1 gene are responsible for DYT6 primary torsion dystonia.
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- Nature Genetics, 2009, v. 41, n. 3, p. 286, doi. 10.1038/ng.304
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- Article
Characterization of Rat ARPP-21 mRNA: Sequence Analysis, Tissue Distribution, and Regulation.
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- Journal of Neurochemistry, 1991, v. 57, n. 6, p. 1985, doi. 10.1111/j.1471-4159.1991.tb06413.x
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- Publication type:
- Article
Stable G protein-effector complexes in striatal neurons: mechanism of assembly and role in neurotransmitter signaling.
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- eLife, 2015, p. 1, doi. 10.7554/eLife.10451
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- Publication type:
- Article
A novel Oprm1-Cre mouse maintains endogenous expression, function and enables detailed molecular characterization of μ-opioid receptor cells.
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- PLoS ONE, 2022, v. 17, n. 12, p. 1, doi. 10.1371/journal.pone.0270317
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- Publication type:
- Article
Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis.
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- Journal of Neuroscience, 2016, v. 36, n. 40, p. 10245, doi. 10.1523/JNEUROSCI.0669-16.2016
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- Publication type:
- Article
CHARACTERIZATION OF BASAL FOREBRAIN CHOLINERGIC NEURONS FROM INDUCED PLURIPOTENT STEM CELLS HARBORING FAMILIAL ALZHEIMER’S MUTATION PSEN2N141I.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P1139, doi. 10.1016/j.jalz.2016.07.020
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- Article
Latrepirdine enhances Aβ degradation in yeast via an autophagic pathway
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- 2010
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- Abstract
Evidence for dose-dependent neurotoxicity of amyloid-β oligomers/Aβ-derived diffusible ligands generated from physiological processing of transgenic human APP in situ in mouse brain
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- 2010
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- Abstract
Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons.
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- Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19319-2
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- Article
Neurobehavioral effects of neonatal opioid exposure in mice: Influence of the OPRM1 SNP.
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- 2020
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- Publication type:
- journal article
Induction of DARPP-32 by Brain-Derived Neurotrophic Factor in Striatal Neurons <i>In Vitro</i> Is Modified by Histone Deacetylase Inhibitors and Nab2.
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- PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076842
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- Publication type:
- Article
Msh2Acts in Medium-Spiny Striatal Neurons as an Enhancer of CAG Instability and Mutant Huntingtin Phenotypes in Huntington's Disease Knock-In Mice.
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- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044273
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- Publication type:
- Article
Molecular and long-term behavioral consequences of neonatal opioid exposure and withdrawal in mice.
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- Frontiers in Behavioral Neuroscience, 2023, p. 1, doi. 10.3389/fnbeh.2023.1202099
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- Publication type:
- Article
TYROBP/DAP12 knockout in Huntington's disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterioration.
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- Journal of Neuroinflammation, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12974-024-03052-4
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- Publication type:
- Article
Correction: miR155, TREM2, INPP5D: Disease stage and cell-type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer's amyloidopathy.
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- 2023
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- Correction Notice
miR155, TREM2, INPP5D: Disease stage and cell type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer's amyloidopathy.
- Published in:
- Journal of Neuroinflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12974-023-02895-7
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- Publication type:
- Article
miR155, TREM2, INPP5D: Disease stage and cell type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer's amyloidopathy.
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- Journal of Neuroinflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12974-023-02895-7
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- Publication type:
- Article
Modulation of Statin-Activated Shedding of Alzheimer APP Ectodomain by ROCK.
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- PLoS Medicine, 2005, v. 2, n. 1, p. 69, doi. 10.1371/journal.pmed.0020018
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- Publication type:
- Article
Proteomic Signaling of Dual-Specificity Phosphatase 4 (DUSP4) in Alzheimer's Disease.
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- Biomolecules (2218-273X), 2024, v. 14, n. 1, p. 66, doi. 10.3390/biom14010066
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- Publication type:
- Article
Transcriptomic Changes Highly Similar to Alzheimer's Disease Are Observed in a Subpopulation of Individuals During Normal Brain Aging.
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- Frontiers in Aging Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnagi.2021.711524
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- Publication type:
- Article
Effect of Aging and a Dual Orexin Receptor Antagonist on Sleep Architecture and Non-REM Oscillations Including an REM Behavior Disorder Phenotype in the PS19 Mouse Model of Tauopathy.
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- Journal of Neuroscience, 2023, v. 43, n. 25, p. 4738, doi. 10.1523/JNEUROSCI.1828-22.2023
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- Publication type:
- Article
Diverse Mechanisms Lead to Common Dysfunction of Striatal Cholinergic Interneurons in Distinct Genetic Mouse Models of Dystonia.
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- Journal of Neuroscience, 2019, v. 39, n. 36, p. 7195, doi. 10.1523/JNEUROSCI.0407-19.2019
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- Publication type:
- Article
CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer's PSEN2<sup>N141I</sup> neurons.
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- Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0475-z
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- Publication type:
- Article
Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in <italic>Drosophila</italic> models.
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- Genome Medicine, 2018, v. 10, p. 1, doi. 10.1186/s13073-018-0530-9
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- Publication type:
- Article
Microglial TYROBP/DAP12 in Alzheimer's disease: Transduction of physiological and pathological signals across TREM2.
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- Molecular Neurodegeneration, 2022, v. 17, n. 1, p. 1, doi. 10.1186/s13024-022-00552-w
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- Publication type:
- Article
VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-0357-x
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- Publication type:
- Article
Postnatal Conditional Deletion of Bcl11b in Striatal Projection Neurons Mimics the Transcriptional Signature of Huntington's Disease.
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- Biomedicines, 2022, v. 10, n. 10, p. N.PAG, doi. 10.3390/biomedicines10102377
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- Article
Abnormal cerebellar function and tremor in a mouse model for non‐manifesting partially penetrant dystonia type 6.
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- Journal of Physiology, 2021, v. 599, n. 7, p. 2037, doi. 10.1113/JP280978
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- Publication type:
- Article