Works by Ehler, Andreas

Results: 7

Novel β‐Glucocerebrosidase Activators That Bind to a New Pocket at a Dimer Interface and Induce Dimerization.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 10, p. 5436, doi. 10.1002/anie.202013890

By:

Benz, Joerg;
Rufer, Arne C.;
Huber, Sylwia;
Ehler, Andreas;
Hug, Melanie;
Topp, Andreas;
Guba, Wolfgang;
Hofmann, Eva Carolina;
Jagasia, Ravi;
Rodríguez Sarmiento, Rosa María

Publication type:

Article

P329G-CAR-J: a novel Jurkat-NFAT-based CAR-T reporter system recognizing the P329G Fc mutation.

Published in:

PEDS: Protein Engineering, Design & Selection, 2019, v. 32, n. 5, p. 207, doi. 10.1093/protein/gzz027

By:

Darowski, Diana;
Jost, Christian;
Stubenrauch, Kay;
Wessels, Uwe;
Benz, Jörg;
Ehler, Andreas;
Freimoser-Grundschober, Anne;
Brünker, Peter;
Mössner, Ekkehard;
Umaña, Pablo;
Kobold, Sebastian;
Klein, Christian

Publication type:

Article

Variable heavy–variable light domain and Fab-arm CrossMabs with charged residue exchanges to enforce correct light chain assembly.

Published in:

PEDS: Protein Engineering, Design & Selection, 2018, v. 31, n. 7/8, p. 289, doi. 10.1093/protein/gzy021

By:

Regula, Joerg Thomas;
Imhof-Jung, Sabine;
Mølhøj, Michael;
Benz, Joerg;
Ehler, Andreas;
Bujotzek, Alexander;
Schaefer, Wolfgang;
Klein, Christian

Publication type:

Article

Prodrug-Activating Chain Exchange (PACE) converts targeted prodrug derivatives to functional bi- or multispecific antibodies.

Published in:

Biological Chemistry, 2022, v. 403, n. 5/6, p. 495, doi. 10.1515/hsz-2021-0401

By:

Dickopf, Steffen;
Buldun, Can;
Vasic, Vedran;
Georges, Guy;
Hage, Carina;
Mayer, Klaus;
Forster, Matthias;
Wessels, Uwe;
Stubenrauch, Kay-Gunnar;
Benz, Jörg;
Ehler, Andreas;
Lauer, Matthias E.;
Ringler, Philippe;
Kobold, Sebastian;
Endres, Stefan;
Klein, Christian;
Brinkmann, Ulrich

Publication type:

Article

Molecular Recognition at the Active Site of Catechol- O-Methyltransferase: Energetically Favorable Replacement of a Water Molecule Imported by a Bisubstrate Inhibitor.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 48, p. 9092, doi. 10.1002/anie.200904410

By:

Ellermann, Manuel;
Jakob-Roetne, Roland;
Lerner, Christian;
Borroni, Edilio;
Schlatter, Daniel;
Roth, Doris;
Ehler, Andreas;
Rudolph, Markus Georg;
Diederich, François

Publication type:

Article

Molecular Recognition at the Active Site of Catechol- O-methyltransferase (COMT): Adenine Replacements in Bisubstrate Inhibitors.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 23, p. 6369, doi. 10.1002/chem.201003648

By:

Ellermann, Manuel;
Paulini, Ralph;
Jakob-Roetne, Roland;
Lerner, Christian;
Borroni, Edilio;
Roth, Doris;
Ehler, Andreas;
Schweizer, W. Bernd;
Schlatter, Daniel;
Rudolph, Markus G.;
Diederich, François

Publication type:

Article

Novel β‐Glucocerebrosidase Activators That Bind to a New Pocket at a Dimer Interface and Induce Dimerization.

Published in:

Angewandte Chemie, 2021, v. 133, n. 10, p. 5496, doi. 10.1002/ange.202013890

By:

Benz, Joerg;
Rufer, Arne C.;
Huber, Sylwia;
Ehler, Andreas;
Hug, Melanie;
Topp, Andreas;
Guba, Wolfgang;
Hofmann, Eva Carolina;
Jagasia, Ravi;
Rodríguez Sarmiento, Rosa María

Publication type:

Article