Works by Efremov, Dimitar G

Results: 35

BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models.

Published in:

Cell Death & Disease, 2020, v. 11, n. 9, p. 1, doi. 10.1038/s41419-020-02944-6

By:

Vervloessem, Tamara;
Sasi, Binu K.;
Xerxa, Elena;
Karamanou, Spyridoula;
Kale, Justin;
La Rovere, Rita M.;
Chakraborty, Supriya;
Sneyers, Flore;
Vogler, Meike;
Economou, Anastassios;
Laurenti, Luca;
Andrews, David W.;
Efremov, Dimitar G.;
Bultynck, Geert

Publication type:

Article

New developments in the management of chronic lymphocytic leukemia: role of ofatumumab.

Published in:

OncoTargets & Therapy, 2016, v. 9, p. 421, doi. 10.2147/OTT.S72845

By:

Laurenti, Luca;
Innocenti, Idanna;
Autore, Francesco;
Sica, Simona;
Efremov, Dimitar G.

Publication type:

Article

The Pathologic Significance of the Immunoglobulins Expressed by Chronic Lymphocytic Leukemia....

Published in:

Leukemia & Lymphoma, 1998, v. 28, n. 3/4, p. 285, doi. 10.3109/10428199809092684

By:

Efremov, Dimitar G.

Publication type:

Article

Rare Hemoglobin Variants: Hb G-Szuhu ( HBB: c.243C>G), Hb G-Coushatta ( HBB: c.68A>C) and Hb Mizuho ( HBB: c.206T>C) in Sri Lankan Families.

Published in:

Hemoglobin, 2015, v. 39, n. 1, p. 62, doi. 10.3109/03630269.2014.992530

By:

Perera, P. Shiromi;
Silva, Ishari;
Hapugoda, Menaka;
Wickramarathne, Merita N.;
Wijesiriwardena, Indira;
Efremov, Dimitar G.;
Fisher, Christopher A.;
Weatherall, David J.;
Premawardhena, Anuja

Publication type:

Article

Anti-tumor activity of selinexor in combination with antineoplastic agents in chronic lymphocytic leukemia.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-44039-0

By:

Vitale, Candida;
Griggio, Valentina;
Todaro, Maria;
Riganti, Chiara;
Jones, Rebecca;
Boccellato, Elia;
Perutelli, Francesca;
Arruga, Francesca;
Vaisitti, Tiziana;
Efremov, Dimitar G.;
Deaglio, Silvia;
Landesman, Yosef;
Bruno, Benedetto;
Coscia, Marta

Publication type:

Article

Anti-tumor activity of selinexor in combination with antineoplastic agents in chronic lymphocytic leukemia.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-44039-0

By:

Vitale, Candida;
Griggio, Valentina;
Todaro, Maria;
Riganti, Chiara;
Jones, Rebecca;
Boccellato, Elia;
Perutelli, Francesca;
Arruga, Francesca;
Vaisitti, Tiziana;
Efremov, Dimitar G.;
Deaglio, Silvia;
Landesman, Yosef;
Bruno, Benedetto;
Coscia, Marta

Publication type:

Article

ABT-199 (Venetoclax), a BH3-mimetic Bcl-2 inhibitor, does not cause Ca<sup>2+</sup> -signalling dysregulation or toxicity in pancreatic acinar cells.

Published in:

2019

By:

Jakubowska, Monika A;
Kerkhofs, Martijn;
Martines, Claudio;
Efremov, Dimitar G;
Gerasimenko, Julia V;
Gerasimenko, Oleg V;
Petersen, Ole H;
Bultynck, Geert;
Vervliet, Tim;
Ferdek, Pawel E

Publication type:

journal article

LDH as Predictive Parameter in Treatment-Naïve Patients Affected by Chronic Lymphocytic Leukemia with Trisomy 12.

Published in:

Clinical Lymphoma, Myeloma & Leukemia, 2018, v. 18, p. S213, doi. 10.1016/j.clml.2018.07.075

By:

Autore, Francesco;
Strati, Paolo;
Innocenti, Idanna;
Corrente, Francesco;
Trentin, Livio;
Cortelezzi, Agostino;
Visco, Carlo;
Coscia, Marta;
Cuneo, Antonio;
Gozzetti, Alessandro;
Mauro, Francesca Romana;
Frustaci, Anna Maria;
Gentile, Massimo;
Morabito, Fortunato;
Molica, Stefano;
Falcucci, Paolo;
D'Arena, Giovanni;
Murru, Roberta;
Vincelli, Donatella;
Efremov, Dimitar G.

Publication type:

Article

Inhibitors of SRC kinases impair antitumor activity of anti-CD20 monoclonal antibodies.

Published in:

mAbs (1942-0862), 2014, v. 6, n. 5, p. 1300, doi. 10.4161/mabs.32106

By:

Winiarska, Magdalena;
Bojarczuk, Kamil;
Pyrzynska, Beata;
Bil, Jacek;
Siernicka, Marta;
Dwojak, Michal;
Bobrowicz, Malgorzata;
Miazek, Nina;
Zapala, Piotr;
Zagozdzon, Agnieszka;
Krol, Magdalena;
Syta, Aleksandra;
Podszywalow-Bartnicka, Paulina;
Pilch, Zofia;
Dabrowska-Iwanicka, Anna;
Juszczynski, Przemyslaw;
Efremov, Dimitar G;
Slabicki, Mikolaj;
Zenz, Thorsten;
Roy, Aude Le

Publication type:

Article

Editorial: The notch signaling pathway in lymphoid malignancies.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1216398

By:

Fais, Franco;
Efremov, Dimitar G.

Publication type:

Article

Chlorambucil plus Rituximab as Front-Line Therapy in Elderly/Unfit Patients Affected by B-Cell Chronic Lymphocytic Leukemia: Results of a Single-Centre Experience.

Published in:

Mediterranean Journal of Hematology & Infectious Diseases, 2013, v. 5, n. 1, p. 1, doi. 10.4084/MJHID.2013.031

By:

Laurenti, Luca;
Vannata, Barbara;
Innocenti, Idanna;
Autore, Francesco;
Santini, Francesco;
Piccirillo, Nicola;
Za, Tommaso;
Bellesi, Silvia;
Marietti, Sara;
Sica, Simona;
Efremov, Dimitar G.;
Leone, Giuseppe

Publication type:

Article

The Use of Monoclonal Antibodies in the Treatment of Autoimmune Complications of Chronic Lymphocytic Leukemia.

Published in:

Mediterranean Journal of Hematology & Infectious Diseases, 2013, v. 5, n. 1, p. 1, doi. 10.4084/MJHID.2013.027

By:

Laurenti, Luca;
Vannata, Barbara;
Innocenti, Idanna;
Autore, Francesco;
Santini, Francesco;
Sica, Simona;
Efremov, Dimitar G.

Publication type:

Article

Novel Agents and Emerging Strategies for Targeting the B-Cell Receptor Pathway in CLL.

Published in:

Mediterranean Journal of Hematology & Infectious Diseases, 2012, v. 4, n. 1, p. 1, doi. 10.4084/MJHID.2012.067

By:

Efremov, Dimitar G.;
Wiestner, Adrian;
Laurenti, Luca

Publication type:

Article

Molecular Subtypes and the Role of TP53 in Diffuse Large B-Cell Lymphoma and Richter Syndrome.

Published in:

Cancers, 2024, v. 16, n. 12, p. 2170, doi. 10.3390/cancers16122170

By:

Negara, Ivan;
Tomuleasa, Ciprian;
Buruiana, Sanda;
Efremov, Dimitar G.

Publication type:

Article

Therapeutic Targets in Chronic Lymphocytic Leukemia.

Published in:

2020

By:

Laurenti, Luca;
Efremov, Dimitar G.

Publication type:

Editorial

Mechanisms of B Cell Receptor Activation and Responses to B Cell Receptor Inhibitors in B Cell Malignancies.

Published in:

Cancers, 2020, v. 12, n. 6, p. 1396, doi. 10.3390/cancers12061396

By:

Efremov, Dimitar G.;
Turkalj, Sven;
Laurenti, Luca

Publication type:

Article

Elevated Lactate Dehydrogenase Has Prognostic Relevance in Treatment-Naïve Patients Affected by Chronic Lymphocytic Leukemia with Trisomy 12.

Published in:

Cancers, 2019, v. 11, n. 7, p. 896, doi. 10.3390/cancers11070896

By:

Autore, Francesco;
Strati, Paolo;
Innocenti, Idanna;
Corrente, Francesco;
Trentin, Livio;
Cortelezzi, Agostino;
Visco, Carlo;
Coscia, Marta;
Cuneo, Antonio;
Gozzetti, Alessandro;
Mauro, Francesca Romana;
Frustaci, Anna Maria;
Gentile, Massimo;
Morabito, Fortunato;
Molica, Stefano;
Falcucci, Paolo;
D'Arena, Giovanni;
Murru, Roberta;
Vincelli, Donatella;
Efremov, Dimitar G

Publication type:

Article

Comparison between oral and intravenous fludarabine plus cyclophosphamide regime as front-line therapy in patients affected by chronic lymphocytic leukaemia: influence of biological parameters on the clinical outcome.

Published in:

Annals of Hematology, 2011, v. 90, n. 1, p. 59, doi. 10.1007/s00277-010-1025-y

By:

Laurenti, Luca;
De Padua, Laura;
Tarnani, Michela;
Piccirillo, Nicola;
Falcucci, Paolo;
D'Arena, Giovanni;
Innocenti, Idanna;
Marietti, Sara;
Efremov, Dimitar G.;
Chiusolo, Patrizia;
Zini, Gina;
Sora', Federica;
Sica, Simona;
Leone, Giuseppe

Publication type:

Article

Pathogen-specific B-cell receptors drive chronic lymphocytic leukemia by light-chain-dependent cross-reaction with autoantigens.

Published in:

EMBO Molecular Medicine, 2017, v. 9, n. 11, p. 1482, doi. 10.15252/emmm.201707732

By:

Jiménez de Oya, Nereida;
De Giovanni, Marco;
Fioravanti, Jessica;
Übelhart, Rudolf;
Di Lucia, Pietro;
Fiocchi, Amleto;
Iacovelli, Stefano;
Efremov, Dimitar G;
Caligaris‐Cappio, Federico;
Jumaa, Hassan;
Ghia, Paolo;
Guidotti, Luca G;
Iannacone, Matteo

Publication type:

Article

Regression of monoclonal B-cell expansion in patients affected by mixed cryoglobulinemia responsive to α-interferon therapy.

Published in:

Cancer (0008543X), 1996, v. 77, n. 12, p. 2604, doi. 10.1002/(SICI)1097-0142(19960615)77:12<2604::AID-CNCR26>3.0.CO;2-V

By:

Mazzaro, Cesare;
Franzin, Francesco;
Tulissi, Patrizia;
Pussini, Elisabetta;
Crovatto, Marina;
Carniello, Giorgio S.;
Efremov, Dimitar G.;
Burrone, Oscar;
Santini, Gianfranco;
Pozzato, Gabriele

Publication type:

Article

Monoclonal gammopathy and serum immunoglobulin levels as prognostic factors in chronic lymphocytic leukaemia.

Published in:

British Journal of Haematology, 2020, v. 190, n. 6, p. 901, doi. 10.1111/bjh.16975

By:

Corbingi, Andrea;
Innocenti, Idanna;
Tomasso, Annamaria;
Pasquale, Raffaella;
Visentin, Andrea;
Varettoni, Marzia;
Flospergher, Elena;
Autore, Francesco;
Morelli, Francesca;
Trentin, Livio;
Reda, Gianluigi;
Efremov, Dimitar G.;
Laurenti, Luca

Publication type:

Article

Venetoclax in CLL patients who progress after B‐cell Receptor inhibitor treatment: a retrospective multi‐centre Italian experience.

Published in:

British Journal of Haematology, 2019, v. 187, n. 1, p. e8, doi. 10.1111/bjh.16123

By:

Innocenti, Idanna;
Morelli, Francesca;
Autore, Francesco;
Piciocchi, Alfonso;
Frustaci, Annamaria;
Mauro, Francesca R.;
Schiattone, Luana;
Trentin, Livio;
Del Poeta, Giovanni;
Reda, Gianluigi;
Rigolin, Gian M.;
Ibatici, Adalberto;
Ciolli, Stefania;
Coscia, Marta;
Sportoletti, Paolo;
Murru, Roberta;
Levato, Luciano;
Gentile, Massimo;
D'Arena, Giovanni;
Efremov, Dimitar G.

Publication type:

Article

B-cell receptor, clinical course and prognosis in chronic lymphocytic leukaemia: the growing saga of the IGHV3 subgroup gene usage.

Published in:

British Journal of Haematology, 2011, v. 153, n. 1, p. 3, doi. 10.1111/j.1365-2141.2010.08440.x

By:

Dal-Bo, Michele;
Del Giudice, Ilaria;
Bomben, Riccardo;
Capello, Daniela;
Bertoni, Francesco;
Forconi, Francesco;
Laurenti, Luca;
Rossi, Davide;
Zucchetto, Antonella;
Pozzato, Gabriele;
Marasca, Roberto;
Efremov, Dimitar G.;
Guarini, Anna;
Del Poeta, Giovanni;
Foà, Robin;
Gaidano, Gianluca;
Gattei, Valter

Publication type:

Article

IGHD3-3 fails to behave as unfavourable prognostic marker in chronic lymphocytic leukaemia.

Published in:

2010

By:

Bomben, Riccardo;
Dal Bo, Michele;
Capello, Daniela;
Forconi, Francesco;
Bertoni, Francesco;
Maffei, Rossana;
Laurenti, Luca;
Rossi, Davide;
Zucca, Emanuele;
Degan, Massimo;
Marasca, Roberto;
Efremov, Dimitar G.;
Del Poeta, Giovanni;
Gaidano, Gianluca;
Gattei, Valter

Publication type:

Letter

G-protein coupled receptor kinase-2 regulates the migration of chronic lymphocytic leukaemia cells to sphingosine-1 phosphate in vitro and their trafficking in vivo.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-91536-5

By:

Cassarino, María Chiara;
Colado, Ana;
Martinez, Valeria Sarapura;
Martines, Claudio;
Bonato, Alice;
Bertini, Martin;
Pavlovksy, Miguel;
Custidiano, Rosario;
Bezares, Fernando Raimundo;
Morande, Pablo Elías;
Vermeulen, Mónica;
Gamberale, Romina;
Giordano, Mirta;
Efremov, Dimitar G;
Borge, Mercedes

Publication type:

Article

The Leukemic Cells of Chronic Lymphocytic Leukemia Patients with Autoimmune Hemolytic Anemia Produce Isotype-switched Immunoglobulins That Are Preferentially Encoded by the 51pl and DP-50 V<sub>H</sub> Genes.

Published in:

Annals of the New York Academy of Sciences, 1997, v. 815, n. 1, p. 443, doi. 10.1111/j.1749-6632.1997.tb52098.x

By:

EFREMOV, DIMITAR G.;
IVANOVSKI, MARTIN;
POZZATO, GABRIELE;
BATISTA, FACUNDO D.;
BURRONE, OSCAR R.

Publication type:

Article

RECENT ADVANCES IN THE PATHOGENESIS AND TREATMENT OF CHRONIC LYMPHOCYTIC LEUKEMIA.

Published in:

Contributions / Prilozi (1857-9345), 2015, v. 35, n. 3, p. 105, doi. 10.1515/prilozi-2015-0015

By:

Efremov, Dimitar G.;
Laurenti, Luca

Publication type:

Article

Genotype-phenotype association analysis identifies the role of α globin genes in modulating disease severity of β thalassaemia intermedia in Sri Lanka.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46674-y

By:

Perera, Shiromi;
Allen, Angela;
Silva, Ishari;
Hapugoda, Menaka;
Wickramarathne, M. Nirmali;
Wijesiriwardena, Indira;
Allen, Stephen;
Rees, David;
Efremov, Dimitar G.;
Fisher, Christopher A.;
Weatherall, David J.;
Premawardhena, Anuja

Publication type:

Article

Low prevalence of chronic hepatitis C virus infection in B-cell non-Hodgkin's lymphoma patients from a population with a high prevalence of healthy Hepatitis c virus carriers.

Published in:

British Journal of Haematology, 2000, v. 109, n. 1, p. 249, doi. 10.1046/j.1365-2141.2000.01950.x

By:

Irina, Panovska;
Borce, Georgievski;
Aleksandar, Stojanovic;
Lidija, Cevreska;
Dimitar G., Efremov

Publication type:

Article

Chronic lymphocytic leukemia: A tale of one or two signals?

Published in:

Cell Research, 2013, v. 23, n. 2, p. 182, doi. 10.1038/cr.2012.152

By:

Chiorazzi, Nicholas;
Efremov, Dimitar G

Publication type:

Article

CD200 and Chronic Lymphocytic Leukemia: Biological and Clinical Relevance.

Published in:

Frontiers in Oncology, 2020, v. 11, p. N.PAG, doi. 10.3389/fonc.2020.584427

By:

D'Arena, Giovanni;
De Feo, Vincenzo;
Pietrantuono, Giuseppe;
Seneca, Elisa;
Mansueto, Giovanna;
Villani, Oreste;
La Rocca, Francesco;
D'Auria, Fiorella;
Statuto, Teodora;
Valvano, Luciana;
Arruga, Francesca;
Deaglio, Silvia;
Efremov, Dimitar G.;
Sgambato, Alessandro;
Laurenti, Luca

Publication type:

Article

A Specific CD44lo CD25lo Subpopulation of Regulatory T Cells Inhibits Anti-Leukemic Immune Response and Promotes the Progression in a Mouse Model of Chronic Lymphocytic Leukemia.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.781364

By:

Goral, Agnieszka;
Firczuk, Malgorzata;
Fidyt, Klaudyna;
Sledz, Marta;
Simoncello, Francesca;
Siudakowska, Karolina;
Pagano, Giulia;
Moussay, Etienne;
Paggetti, Jérôme;
Nowakowska, Patrycja;
Gobessi, Stefania;
Barankiewicz, Joanna;
Salomon-Perzynski, Aleksander;
Benvenuti, Federica;
Efremov, Dimitar G.;
Juszczynski, Przemyslaw;
Lech-Maranda, Ewa;
Muchowicz, Angelika

Publication type:

Article

Autoimmune hemolytic anemia during bendamustine plus rituximab treatment in CLL patients: multicenter experience.

Published in:

2016

By:

Laurenti, Luca;
Autore, Francesco;
Innocenti, Idanna;
D'Arena, Giovanni;
Coscia, Marta;
Mondello, Patrizia;
Chiusolo, Patrizia;
Bellesi, Silvia;
Efremov, Dimitar G.;
Sica, Simona;
Mauro, Francesca Romana

Publication type:

Letter to the Editor

Molecular and clinical features of chronic lymphocytic leukemia with stereotyped B-cell receptors in a Ukrainian cohort.

Published in:

Leukemia & Lymphoma, 2010, v. 51, n. 5, p. 822, doi. 10.3109/10428191003646002

By:

Bilous, Nadiia;
Bomben, Riccardo;
Dal Bo, Michele;
Capello, Daniela;
Forconi, Francesco;
Laurenti, Luca;
Bertoni, Francesco;
Efremov, Dimitar G.;
Marasca, Roberto;
Del Poeta, Giovanni;
Martina, Zoya;
Kryachouk, Iryna;
Dyagil, Iryna;
Gaidano, Gianluca;
Chumak, Anatoliy;
Gattei, Valter;
Abramenko, Iryna

Publication type:

Article

Treatment approach for elderly and unfit patients with chronic lymphocytic leukemia.

Published in:

Expert Review of Hematology, 2017, v. 10, n. 12, p. 1069, doi. 10.1080/17474086.2017.1398642

By:

Innocenti, Idanna;
Autore, Francesco;
Pasquale, Raffaella;
Morelli, Francesca;
Efremov, Dimitar G;
Laurenti, Luca

Publication type:

Article