Works by Efferth, Thomas

Results: 286

Drug Repurposing to Inhibit Oncostatin M in Crohn's Disease.

Published in:

Molecules, 2025, v. 30, n. 9, p. 1897, doi. 10.3390/molecules30091897

By:

Bahramimehr, Faranak;
Guthart, Axel;
Kurz, Stefanie;
Hai, Yuanping;
Dawood, Mona;
Yücer, Rümeysa;
Shahhamzehei, Nasim;
Weiskirchen, Ralf;
Roth, Wilfried;
Stremmel, Wolfgang;
Bringmann, Gerhard;
Efferth, Thomas

Publication type:

Article

Cytochrome P450 reaction phenotyping and inhibition and induction studies of pinostrobin in human liver microsomes and hepatocytes.

Published in:

Biomedical Chromatography, 2017, v. 31, n. 6, p. n/a, doi. 10.1002/bmc.3888

By:

Tan, Shengnan;
Dong, Zhimin;
Zhang, Jiashuo;
Efferth, Thomas;
Fu, Yujie;
Hua, Xin

Publication type:

Article

Sensitivity and resistance towards isoliquiritigenin, doxorubicin and methotrexate in T cell acute lymphoblastic leukaemia cell lines by pharmacogenomics.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2010, v. 382, n. 3, p. 221, doi. 10.1007/s00210-010-0541-6

By:

Youns, Mahmoud;
Fu, Yu-Jie;
Zu, Yuan-Gang;
Kramer, Anne;
Konkimalla, V.;
Radlwimmer, Bernhard;
Sültmann, Holger;
Efferth, Thomas

Publication type:

Article

Molecular modes of action of cephalotaxine and homoharringtonine from the coniferous tree Cephalotaxus hainanensis in human tumor cell lines.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2003, v. 367, n. 1, p. 56, doi. 10.1007/s00210-002-0632-0

By:

Efferth, Thomas;
Sauerbrey, Axel;
Halatsch, Marc-Eric;
Ross, Douglas D.;
Gebhart, Erich

Publication type:

Article

Antimicrobial activity and cytotoxicity towards cancer cells of Melaleuca alternifolia (tea tree) oil.

Published in:

European Food Research & Technology, 2009, v. 229, n. 2, p. 247, doi. 10.1007/s00217-009-1057-5

By:

Liu, Xia;
Zu, Yuangang;
Fu, Yujie;
Yao, Liping;
Gu, Chengbo;
Wang, Wei;
Efferth, Thomas

Publication type:

Article

Rapid microwave-assisted transesterification for the preparation of fatty acid methyl esters from the oil of yellow horn ( Xanthoceras sorbifolia Bunge.).

Published in:

European Food Research & Technology, 2009, v. 229, n. 1, p. 43, doi. 10.1007/s00217-009-1024-1

By:

Yuangang Zu;
Su Zhang;
Yujie Fu;
Wei Liu;
Zhiguo Liu;
Meng Luo;
Efferth, Thomas

Publication type:

Article

Immunohistochemical Detection of P Glycoprotein, Glutathione S Transferase and DNATopoisomerase II in Human Tumors.

Published in:

Oncology, 1992, v. 49, n. 5, p. 368, doi. 10.1159/000227075

By:

Efferth, Thomas;
Mattern, Jürgen;
Volm, Manfred

Publication type:

Article

Artemisinin Derivatives Target Topoisomerase 1 and Cause DNA Damage in Silico and in Vitro.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00711

By:

Kadioglu, Onat;
Ariel Chan;
Cong Ling Qiu, Alena;
Kam Wai Wong, Vincent;
Colligs, Vanessa;
Wecklein, Sabine;
Rached, Halima Freund-Henni;
Efferth, Thomas;
Wen-Luan Wendy Hsiao

Publication type:

Article

North African Medicinal Plants Traditionally Used in Cancer Therapy.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00383

By:

Alves-Silva, Jorge M.;
Romane, Abderrahmane;
Efferth, Thomas;
Salgueiro, Lígia

Publication type:

Article

Potential of Central, Eastern and Western Africa Medicinal Plants for Cancer Therapy: Spotlight on Resistant Cells and Molecular Targets.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00343

By:

Mbaveng, Armelle T.;
Kuete, Victor;
Efferth, Thomas

Publication type:

Article

Mode of Action Analyses of Neferine, a Bisbenzylisoquinoline Alkaloid of Lotus (Nelumbo nucifera) against Multidrug-Resistant Tumor Cells.

Published in:

Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00238

By:

Kadioglu, Onat;
Law, Betty Y. K.;
Mok, Simon W. F.;
Su-Wei Xu;
Efferth, Thomas;
Wong, Vincent K. W.

Publication type:

Article

Identification of NF-κB as Determinant of Posttraumatic Stress Disorder and Its Inhibition by the Chinese Herbal Remedy Free and Easy Wanderer.

Published in:

Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00181

By:

Chunlan Hong;
Schüffler, Anja;
Kauhl, Ulrich;
Jingming Cao;
Ching-Fen Wu;
Opatz, Till;
Thines, Eckhard;
Efferth, Thomas

Publication type:

Article

Drug Repurposing of the Anthelmintic Niclosamide to Treat Multidrug-Resistant Leukemia.

Published in:

Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00110

By:

Hamdoun, Sami;
Jung, Philipp;
Efferth, Thomas

Publication type:

Article

Theabrownin Inhibits Cell Cycle Progression and Tumor Growth of Lung Carcinoma through c-myc-Related Mechanism.

Published in:

Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00075

By:

Li Zhou;
Feifei Wu;
Wangdong Jin;
Bo Yan;
Xin Chen;
Yingfei He;
Weiji Yang;
Wenlin Du;
Qiang Zhang;
Yonghua Guo;
Qiang Yuan;
Xiaoqiao Dong;
Wenhua Yu;
Jin Zhang;
Luwei Xiao;
Peijian Tong;
Letian Shan;
Efferth, Thomas

Publication type:

Article

Pharmacogenomic Characterization and Isobologram Analysis of the Combination of Ascorbic Acid and Curcumin--Two Main Metabolites of Curcuma longa--in Cancer Cells.

Published in:

Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00038

By:

Ooko, Edna;
Kadioglu, Onat;
Greten, Henry J.;
Efferth, Thomas;
Ghosh, Subhalakshmi;
Fumiaki Uchiumi

Publication type:

Article

Anti-Proliferative and Apoptosis-Inducing Effect of Theabrownin against Non-small Cell Lung Adenocarcinoma A549 Cells.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00465

By:

Feifei Wu;
Li Zhou;
Wangdong Jin;
Weiji Yang;
Ying Wang;
Bo Yan;
Wenlin Du;
Qiang Zhang;
Lei Zhang;
Yonghua Guo;
Jin Zhang;
Shan, Letian;
Efferth, Thomas

Publication type:

Article

Both Phenolic and Non-phenolic Green Tea Fractions Inhibit Migration of Cancer Cells.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00398

By:

Ean-Jeong Seo;
Ching-Fen Wu;
Ali, Zulfiqar;
Yan-Hong Wang;
Khan, Shabana I.;
Walker, Larry A.;
Khan, Ikhlas A.;
Efferth, Thomas

Publication type:

Article

Anti-inflammatory Effects of Herbal Preparations STW5 and STW5-II in Cytokine-Challenged Normal Human Colon Cells.

Published in:

Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00393

By:

Schneider, Mathias;
Efferth, Thomas;
Abdel-Aziz, Heba;
Fang-Rong Chang;
Jian Li;
Cañigueral, Salvador

Publication type:

Article

A Multicenter, Single-Blind, Case-Control, Immunohistochemical Study of Orbital Tissue in Thyroid Eye Disease.

Published in:

Thyroid, 2022, v. 32, n. 12, p. 1547, doi. 10.1089/thy.2022.0173

By:

Hai, Yuan-Ping;
Saeed, Mohamed E.M.;
Ponto, Katharina A.;
Elflein, Heike M.;
Lee, Alan Chun Hong;
Fang, Sijie;
Zhou, Huifang;
Frommer, Lara;
Längericht, Jan;
Efferth, Thomas;
Kahaly, George J.

Publication type:

Article

XCP1 cleaves Pathogenesis-related protein 1 into CAPE9 for systemic immunity in Arabidopsis.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40406-7

By:

Chen, Ying-Lan;
Lin, Fan-Wei;
Cheng, Kai-Tan;
Chang, Chi-Hsin;
Hung, Sheng-Chi;
Efferth, Thomas;
Chen, Yet-Ran

Publication type:

Article

The Histogenetic Origin of Malignant Cells Predicts Their Susceptibility towards Synthetic Lethality Utilizing the TK.007 System.

Published in:

Cancers, 2024, v. 16, n. 12, p. 2278, doi. 10.3390/cancers16122278

By:

Pallasch, Fabian Bernhard;
Freytag, Vera;
Kriegs, Malte;
Gatzemeier, Dennis;
Mair, Thomas;
Voss, Hannah;
Riecken, Kristoffer;
Dawood, Mona;
Fehse, Boris;
Efferth, Thomas;
Schlüter, Hartmut;
Schumacher, Udo

Publication type:

Article

In Silico, In Vitro, and In Vivo Investigations on Adapalene as Repurposed Third Generation Retinoid against Multiple Myeloma and Leukemia.

Published in:

Cancers, 2023, v. 15, n. 16, p. 4136, doi. 10.3390/cancers15164136

By:

Boulos, Joelle C.;
Chatterjee, Manik;
Shan, Letian;
Efferth, Thomas

Publication type:

Article

Expression of Chemoresistance-Associated ABC Proteins in Hepatobiliary, Pancreatic and Gastrointestinal Cancers.

Published in:

Cancers, 2022, v. 14, n. 14, p. N.PAG, doi. 10.3390/cancers14143524

By:

Marin, Jose J. G.;
Monte, Maria J.;
Macias, Rocio I. R.;
Romero, Marta R.;
Herraez, Elisa;
Asensio, Maitane;
Ortiz-Rivero, Sara;
Cives-Losada, Candela;
Giacomo, Silvia Di;
Gonzalez-Gallego, Javier;
Mauriz, Jose L.;
Efferth, Thomas;
Briz, Oscar

Publication type:

Article

Shikonin Inhibits Cell Growth of Sunitinib-Resistant Renal Cell Carcinoma by Activating the Necrosome Complex and Inhibiting the AKT/mTOR Signaling Pathway.

Published in:

Cancers, 2022, v. 14, n. 5, p. 1114, doi. 10.3390/cancers14051114

By:

Markowitsch, Sascha D.;
Vakhrusheva, Olesya;
Schupp, Patricia;
Akele, Yasminn;
Kitanovic, Jovana;
Slade, Kimberly S.;
Efferth, Thomas;
Thomas, Anita;
Tsaur, Igor;
Mager, René;
Haferkamp, Axel;
Juengel, Eva

Publication type:

Article

Epigenetic Alterations Upstream and Downstream of p53 Signaling in Colorectal Carcinoma.

Published in:

Cancers, 2021, v. 13, n. 16, p. 4072, doi. 10.3390/cancers13164072

By:

Tomicic, Maja T.;
Dawood, Mona;
Efferth, Thomas

Publication type:

Article

The Role of p53 Dysfunction in Colorectal Cancer and Its Implication for Therapy.

Published in:

Cancers, 2021, v. 13, n. 10, p. 2296, doi. 10.3390/cancers13102296

By:

Michel, Maurice;
Kaps, Leonard;
Maderer, Annett;
Galle, Peter R.;
Moehler, Markus;
Tomicic, Maja T.;
Efferth, Thomas

Publication type:

Article

Platinum Complexes in Colorectal Cancer and Other Solid Tumors.

Published in:

Cancers, 2021, v. 13, n. 9, p. 2073, doi. 10.3390/cancers13092073

By:

Köberle, Beate;
Schoch, Sarah;
Tomicic, Maja T.;
Efferth, Thomas

Publication type:

Article

Shikonin Reduces Growth of Docetaxel-Resistant Prostate Cancer Cells Mainly through Necroptosis.

Published in:

Cancers, 2021, v. 13, n. 4, p. 882, doi. 10.3390/cancers13040882

By:

Markowitsch, Sascha D.;
Juetter, Kira M.;
Schupp, Patricia;
Hauschulte, Kristine;
Vakhrusheva, Olesya;
Slade, Kimberly Sue;
Thomas, Anita;
Tsaur, Igor;
Cinatl Jr., Jindrich;
Michaelis, Martin;
Efferth, Thomas;
Haferkamp, Axel;
Juengel, Eva;
Heidegger-Pircher, Isabel

Publication type:

Article

Artesunate Inhibits Growth of Sunitinib-Resistant Renal Cell Carcinoma Cells through Cell Cycle Arrest and Induction of Ferroptosis.

Published in:

Cancers, 2020, v. 12, n. 11, p. 3150, doi. 10.3390/cancers12113150

By:

Markowitsch, Sascha D.;
Schupp, Patricia;
Lauckner, Julia;
Vakhrusheva, Olesya;
Slade, Kimberly S.;
Mager, René;
Efferth, Thomas;
Haferkamp, Axel;
Juengel, Eva

Publication type:

Article

Synthesis of novel xanthone and acridone carboxamides with potent antiproliferative activities.

Published in:

Arabian Journal of Chemistry, 2020, v. 13, n. 11, p. 7953, doi. 10.1016/j.arabjc.2020.09.025

By:

Georgakopoulos, Antonios;
Kalampaliki, Amalia D.;
Gioti, Katerina;
Hamdoun, Sami;
Giannopoulou, Aikaterini F.;
Efferth, Thomas;
Stravopodis, Dimitrios J.;
Tenta, Roxane;
Marakos, Panagiotis;
Pouli, Nicole;
Kostakis, Ioannis K.

Publication type:

Article

Qigong therapy for physiotherapists suffering from burnout: a preliminary study.

Published in:

Journal of Chinese Integrative Medicine, 2012, v. 10, n. 11, p. 1233, doi. 10.3736/jcim20121106

By:

Saganha, Joao Pedro;
Doenitz, Christoph;
Greten, Tobias;
Efferth, Thomas;
Greten, Henry J.

Publication type:

Article

Effects of qigong on performance-related anxiety and physiological stress functions in transverse flute music schoolchildren: a feasibility study.

Published in:

Journal of Chinese Integrative Medicine, 2012, v. 10, n. 8, p. 858, doi. 10.3736/jcim20120805

By:

Sousa, Claudia Maria;
Gonoalves, Mario;
Machado, Jorge;
Efferth, Thomas;
Greten, Tobias;
Froeschen, Petra;
Greten, Henry J.

Publication type:

Article

Can heat and cold be parameterized? Clinical data of a preliminary study.

Published in:

Journal of Chinese Integrative Medicine, 2012, v. 10, n. 5, p. 532, doi. 10.3736/jcim20120508

By:

Doenitz, Christoph A.;
Anjos, Ana;
Efferth, Thomas;
Greten, Tobias;
Greten, Henry J.

Publication type:

Article

The European directive on traditional herbal medicinal products: friend or for plant-based therapies?

Published in:

Journal of Chinese Integrative Medicine, 2012, v. 10, n. 4, p. 357, doi. 10.3736/jcim20120401

By:

Efferth, Thomas;
Greten, Henry Johannes

Publication type:

Article

Transport processes of radiopharmaceuticals and -modulators.

Published in:

2011

By:

Efferth, Thomas;
Langguth, Peter

Publication type:

journal article

Cardiotoxicity and Cardioprotection by Artesunate in Larval Zebrafish.

Published in:

Dose-Response, 2020, v. 18, n. 1, p. 1, doi. 10.1177/1559325819897180

By:

Zheng, Chuanrui;
Shan, Letian;
Tong, Peijian;
Efferth, Thomas

Publication type:

Article

Cytotoxicity of methanol extracts of 10 Cameroonian medicinal plants towards multi-factorial drug-resistant cancer cell lines.

Published in:

BMC Complementary & Alternative Medicine, 2016, v. 16, p. 1, doi. 10.1186/s12906-016-1253-3

By:

Kuete, Victor;
Tchinda, Cedric F.;
Mambe, Flora T.;
Beng, Veronique P.;
Efferth, Thomas

Publication type:

Article

Cytotoxicity of selected Cameroonian medicinal plants and Nauclea pobeguinii towards multi-factorial drug-resistant cancer cells.

Published in:

BMC Complementary & Alternative Medicine, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12906-015-0841-y

By:

Kuete, Victor;
Sandjo, Louis P.;
Mbaveng, Armelle T.;
Seukep, Jackson A.;
Ngadjui, Bonaventure T.;
Efferth, Thomas

Publication type:

Article

Cytotoxicity of selected Cameroonian medicinal plants and Nauclea pobeguinii towards multi-factorial drug-resistant cancer cells.

Published in:

BMC Complementary & Alternative Medicine, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12906-015-0841-y

By:

Kuete, Victor;
Sandjo, Louis P.;
Mbaveng, Armelle T.;
Seukep, Jackson A.;
Ngadjui, Bonaventure T.;
Efferth, Thomas

Publication type:

Article

Cytotoxicity of four Aframomum species (A. arundinaceum, A. alboviolaceum, A. kayserianum and A. polyanthum) towards multi-factorial drug resistant cancer cell lines.

Published in:

BMC Complementary & Alternative Medicine, 2014, v. 14, p. 1, doi. 10.1186/1472-6882-14-340

By:

Kuete, Victor;
Ango, Patrick Y.;
Yeboah, Samuel O.;
Mbaveng, Armelle T.;
Mapitse, Renameditswe;
Kapche, Gilbert D. W. F.;
Ngadjui, Bonaventure T.;
Efferth, Thomas

Publication type:

Article

Cytotoxicity of Elaoephorbia drupifera and other Cameroonian medicinal plants against drug sensitive and multidrug resistant cancer cells.

Published in:

BMC Complementary & Alternative Medicine, 2013, v. 13, n. 1, p. 250, doi. 10.1186/1472-6882-13-250

By:

Victor Kuete, Victor Kuete;
Voukeng, Igor K.;
Tsobou, Roger;
Mbaveng, Armelle T.;
Wiench, Benjamin;
Beng, Veronique P.;
Efferth, Thomas

Publication type:

Article

Cytotoxicity, mode of action and antibacterial activities of selected Saudi Arabian medicinal plants.

Published in:

BMC Complementary & Alternative Medicine, 2013, v. 13, n. 1, p. 354, doi. 10.1186/1472-6882-13-354

By:

Kuete, Victor;
Wiench, Benjamin;
Alsaid, Mansour S.;
Alyahya, Muhammad A.;
Fankam, Aimé G.;
Shahat, Abdelaaty A.;
Efferth, Thomas

Publication type:

Article

A phenolic ester from Aglaia loheri leaves reveals cytotoxicity towards sensitive and multidrug-resistant cancer cells.

Published in:

BMC Complementary & Alternative Medicine, 2013, v. 13, n. 1, p. 286, doi. 10.1186/1472-6882-13-286

By:

Dapat, Else;
Jacinto, Sonia;
Efferth, Thomas

Publication type:

Article

Targeting epigenetics in cancer: therapeutic potential of flavonoids.

Published in:

2021

By:

Khan, Haroon;
Belwal, Tarun;
Efferth, Thomas;
Farooqi, Ammad Ahmad;
Sanches-Silva, Ana;
Vacca, Rosa Anna;
Nabavi, Seyed Fazel;
Khan, Fazlullah;
Prasad Devkota, Hari;
Barreca, Davide;
Sureda, Antoni;
Tejada, Silvia;
Dacrema, Marco;
Daglia, Maria;
Suntar, İpek;
Xu, Suowen;
Ullah, Hammad;
Battino, Maurizio;
Giampieri, Francesca;
Nabavi, Seyed Mohammad

Publication type:

journal article

Fighting Cancer with Red Wine? Molecular Mechanisms of Resveratrol.

Published in:

Critical Reviews in Food Science & Nutrition, 2009, v. 49, n. 9, p. 782, doi. 10.1080/10408390802248627

By:

Kraft, Thomas E.;
Parisotto, Daniel;
Schempp, Christina;
Efferth, Thomas

Publication type:

Article

Prospecting for cytotoxic and antiprotozoal 4‐aryl‐4H‐chromenes and 10‐aryldihydropyrano[2,3‐f]chromenes.

Published in:

Archiv der Pharmazie, 2018, v. 351, n. 10, p. 1, doi. 10.1002/ardp.201800100

By:

Martin, Erlon F.;
Mbaveng, Armelle T.;
de Moraes, Milene H.;
Kuete, Victor;
Biavatti, Maique W.;
Steindel, Mario;
Efferth, Thomas;
Sandjo, Louis P.

Publication type:

Article

The immunosuppressive activity of artemisinin‐type drugs towards inflammatory and autoimmune diseases.

Published in:

Medicinal Research Reviews, 2021, v. 41, n. 6, p. 3023, doi. 10.1002/med.21842

By:

Efferth, Thomas;
Oesch, Franz

Publication type:

Article

Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress‐ and aging‐related diseases.

Published in:

Medicinal Research Reviews, 2021, v. 41, n. 1, p. 630, doi. 10.1002/med.21743

By:

Panossian, Alexander G.;
Efferth, Thomas;
Shikov, Alexander N.;
Pozharitskaya, Olga N.;
Kuchta, Kenny;
Mukherjee, Pulok K.;
Banerjee, Subhadip;
Heinrich, Michael;
Wu, Wanying;
Guo, De‐an;
Wagner, Hildebert

Publication type:

Article

Sister chromatid exchange-inducing DNA lesions and depression of activation markers on the surface of cultured peripheral blood mononuclear cells after the addition of streptococcal pyrogenic exotoxins A and C.

Published in:

Medical Microbiology & Immunology, 1995, v. 184, n. 2, p. 87, doi. 10.1007/BF00221392

By:

Büssing, Arndt;
Klotz, Martina;
Suzart, Kiliana;
Efferth, Thomas;
Gerlach, Dieter;
Schnitzler, Norbert;
Osieka, Reinhardt;
Schweizer, Klaus;
Kaufhold, Achim

Publication type:

Article

The Effect of Plastic-Related Compounds on Transcriptome-Wide Gene Expression on CYP2C19-Overexpressing HepG2 Cells.

Published in:

Molecules, 2023, v. 28, n. 16, p. 5952, doi. 10.3390/molecules28165952

By:

Rosellini, Matteo;
Schulze, Alicia;
Omer, Ejlal A.;
Ali, Nadeen T.;
Marini, Federico;
Küpper, Jan-Heiner;
Efferth, Thomas

Publication type:

Article