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Low Multiplicity of HIV-1 Infection and No Vaccine Enhancement in VAX003 Injection Drug Users.
Published in:
Open Forum Infectious Diseases, 2014, v. 1, n. 2, p. 1, doi. 10.1093/ofid/ofu056
By:
- Sterrett, Sarah;
- Learn, Gerald H.;
- Edlefsen, Paul T.;
- Haynes, Barton F.;
- Hahn, Beatrice H.;
- Shaw, George M.;
- Bar, Katharine J.
Publication type:
Article
Assessing vaccine-mediated protection in an ultra-low dose Mycobacterium tuberculosis murine model.
Published in:
PLoS Pathogens, 2023, v. 19, n. 11, p. 1, doi. 10.1371/journal.ppat.1011825
By:
- Plumlee, Courtney R.;
- Barrett, Holly W.;
- Shao, Danica E.;
- Lien, Katie A.;
- Cross, Lauren M.;
- Cohen, Sara B.;
- Edlefsen, Paul T.;
- Urdahl, Kevin B.
Publication type:
Article
FCCR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial.
Published in:
Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3879, doi. 10.1172/JCI75539
By:
- Shuying S. Li;
- Gilbert, Peter B.;
- Tomaras, Georgia D.;
- Kijak, Gustavo;
- Ferrari, Guido;
- Thomas, Rasmi;
- Chul-Woo Pyo;
- Zolla-Pazner, Susan;
- Montefiori, David;
- Hua-Xin Liao;
- Nabel, Gary;
- Pinter, Abraham;
- Evans, David T.;
- Gottardo, Raphael;
- Dai, James Y.;
- Janes, Holly;
- Morris, Daryl;
- Youyi Fong;
- Edlefsen, Paul T.;
- Fusheng Li
Publication type:
Article
B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers.
Published in:
Nature Medicine, 2015, v. 21, n. 2, p. 132, doi. 10.1038/nm.3781
By:
- Fukazawa, Yoshinori;
- Lum, Richard;
- Okoye, Afam A;
- Park, Haesun;
- Matsuda, Kenta;
- Bae, Jin Young;
- Hagen, Shoko I;
- Shoemaker, Rebecca;
- Deleage, Claire;
- Lucero, Carissa;
- Morcock, David;
- Swanson, Tonya;
- Legasse, Alfred W;
- Axthelm, Michael K;
- Hesselgesser, Joseph;
- Geleziunas, Romas;
- Hirsch, Vanessa M;
- Edlefsen, Paul T;
- Piatak, Michael;
- Estes, Jacob D
Publication type:
Article
CD8 and CD4 Epitope Predictions in RV144: No Strong Evidence of a T-Cell Driven Sieve Effect in HIV-1 Breakthrough Sequences from Trial Participants.
Published in:
PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0111334
By:
- Dommaraju, Kalpana;
- Kijak, Gustavo;
- Carlson, Jonathan M.;
- Larsen, Brendan B.;
- Tovanabutra, Sodsai;
- Geraghty, Dan E.;
- Deng, Wenjie;
- Maust, Brandon S.;
- Edlefsen, Paul T.;
- Sanders-Buell, Eric;
- Ratto-Kim, Silvia;
- deSouza, Mark S.;
- Rerks-Ngarm, Supachai;
- Nitayaphan, Sorachai;
- Pitisuttihum, Punnee;
- Kaewkungwal, Jaranit;
- O'Connell, Robert J.;
- Robb, Merlin L.;
- Michael, Nelson L.;
- Mullins, James I.
Publication type:
Article
No Evidence of Pritelivir Resistance Among Herpes Simplex Virus Type 2 Isolates After 4 Weeks of Daily Therapy.
Published in:
2016
By:
- Edlefsen, Paul T.;
- Birkmann, Alexander;
- Meei-Li Huang;
- Magaret, Craig A.;
- Jia Jin Kee;
- Diem, Kurt;
- Goldner, Thomas;
- Timmler, Burkhard;
- Stoelben, Susanne;
- Ruebsamen-Schaeff, Helga;
- Zimmermann, Holger;
- Warren, Terri;
- Wald, Anna;
- Corey, Lawrence;
- Huang, Meei-Li;
- Kee, Jia Jin
Publication type:
journal article
Correction: RV144 HIV-1 vaccination impacts post-infection antibody responses.
Published in:
2021
By:
- Mdluli, Thembi;
- Jian, Ningbo;
- Slike, Bonnie;
- Paquin-Proulx, Dominic;
- Donofrio, Gina;
- Alrubayyi, Aljawharah;
- Gift, Syna;
- Grande, Rebecca;
- Bryson, Mary;
- Lee, Anna;
- Dussupt, Vincent;
- Mendez-Rivera, Letzibeth;
- Sanders-Buell, Eric;
- Chenine, Agnès-Laurence;
- Tran, Ursula;
- Li, Yifan;
- Brown, Eric;
- Edlefsen, Paul T.;
- O'Connell, Robert;
- Gilbert, Peter
Publication type:
Correction Notice
Comprehensive Sieve Analysis of Breakthrough HIV-1 Sequences in the RV144 Vaccine Efficacy Trial.
Published in:
PLoS Computational Biology, 2015, v. 11, n. 2, p. 1, doi. 10.1371/journal.pcbi.1003973
By:
- Edlefsen, Paul T.;
- Rolland, Morgane;
- Hertz, Tomer;
- Tovanabutra, Sodsai;
- Gartland, Andrew J.;
- deCamp, Allan C.;
- Magaret, Craig A.;
- Ahmed, Hasan;
- Gottardo, Raphael;
- Juraska, Michal;
- McCoy, Connor;
- Larsen, Brendan B.;
- Sanders-Buell, Eric;
- Carrico, Chris;
- Menis, Sergey;
- Bose, Meera;
- null, null;
- Arroyo, Miguel A.;
- O’Connell, Robert J.;
- Nitayaphan, Sorachai
Publication type:
Article
B cells, antibody-secreting cells, and virus-specific antibodies respond to herpes simplex virus 2 reactivation in skin.
Published in:
2021
By:
- Ford, Emily S.;
- Sholukh, Anton M.;
- Boytz, RuthMabel;
- Carmack, Savanna S.;
- Klock, Alexis;
- Phasouk, Khamsone;
- Danica Shao;
- Rossenkhan, Raabya;
- Edlefsen, Paul T.;
- Tao Peng;
- Johnston, Christine;
- Wald, Anna;
- Jia Zhu;
- Corey, Lawrence;
- Shao, Danica;
- Peng, Tao;
- Zhu, Jia
Publication type:
journal article
CD8+ T cells fail to limit SIV reactivation following ART withdrawal until after viral amplification.
Published in:
2021
By:
- Okoye, Afam A.;
- Duell, Derick D.;
- Fukazawa, Yoshinori;
- Varco-Merth, Benjamin;
- Marenco, Alejandra;
- Behrens, Hannah;
- Chaunzwa, Morgan;
- Selseth, Andrea N.;
- Gilbride, Roxanne M.;
- Shao, Jason;
- Edlefsen, Paul T.;
- Geleziunas, Romas;
- Pinkevych, Mykola;
- Davenport, Miles P.;
- Busman-Sahay, Kathleen;
- Nekorchuk, Michael;
- Park, Haesun;
- Smedley, Jeremy;
- Axthelm, Michael K.;
- Estes, Jacob D.
Publication type:
journal article
A live-attenuated RhCMV/SIV vaccine shows long-term efficacy against heterologous SIV challenge.
Published in:
Science Translational Medicine, 2019, v. 11, n. 501, p. 1, doi. 10.1126/scitranslmed.aaw2607
By:
- Hansen, Scott G.;
- Marshall, Emily E.;
- Malouli, Daniel;
- Ventura, Abigail B.;
- Hughes, Colette M.;
- Ainslie, Emily;
- Ford, Julia C.;
- Morrow, David;
- Gilbride, Roxanne M.;
- Bae, Jin Y.;
- Legasse, Alfred W.;
- Oswald, Kelli;
- Shoemaker, Rebecca;
- Berkemeier, Brian;
- Bosche, William J.;
- Hull, Michael;
- Womack, Jennie;
- Shao, Jason;
- Edlefsen, Paul T.;
- Reed, Jason S.
Publication type:
Article
Enhancing safety of cytomegalovirus-based vaccine vectors by engaging host intrinsic immunity.
Published in:
Science Translational Medicine, 2019, v. 11, n. 501, p. 1, doi. 10.1126/scitranslmed.aaw2603
By:
- Marshall, Emily E.;
- Malouli, Daniel;
- Hansen, Scott G.;
- Gilbride, Roxanne M.;
- Hughes, Colette M.;
- Ventura, Abigail B.;
- Ainslie, Emily;
- Selseth, Andrea N.;
- Ford, Julia C.;
- Burke, David;
- Kreklywich, Craig N.;
- Womack, Jennie;
- Legasse, Alfred W.;
- Axthelm, Michael K.;
- Kahl, Christoph;
- Streblow, Daniel;
- Edlefsen, Paul T.;
- Picker, Louis J.;
- Früh, Klaus
Publication type:
Article
Observational study of effects of HIV acquisition and antiretroviral treatment on biomarkers of systemic immune activation.
Published in:
PLoS ONE, 2024, v. 19, n. 7, p. 1, doi. 10.1371/journal.pone.0288895
By:
- Kosmider, Ewelina;
- Wallner, Jackson;
- Gervassi, Ana;
- Bender Ignacio, Rachel A.;
- Pinto-Santini, Delia;
- Gornalusse, German;
- Pandey, Urvashi;
- Hladik, Florian;
- Edlefsen, Paul T.;
- Lama, Javier R.;
- Duerr, Ann C.;
- Frenkel, Lisa M.
Publication type:
Article
Feeding-Related Gut Microbial Composition Associates With Peripheral T-Cell Activation and Mucosal Gene Expression in African Infants.
Published in:
Clinical Infectious Diseases, 2018, v. 67, n. 8, p. 1237, doi. 10.1093/cid/ciy265
By:
- Wood, Lianna F;
- Brown, Bryan P;
- Lennard, Katie;
- Karaoz, Ulas;
- Havyarimana, Enock;
- Passmore, Jo-Ann S;
- Hesseling, Anneke C;
- Edlefsen, Paul T;
- Kuhn, Louise;
- Mulder, Nicola
Publication type:
Article
Myeloid‐derived suppressor cells and their association with vaccine immunogenicity in South African infants.
Published in:
Journal of Leukocyte Biology, 2021, v. 110, n. 5, p. 939, doi. 10.1002/JLB.5A0420-281R
By:
- Kidzeru, Elvis;
- Gasper, Melanie A.;
- Shao, Danica;
- Edlefsen, Paul T.;
- Lejarcegui, Nicholas;
- Havyarimana, Enock;
- Urdahl, Kevin;
- Gantt, Soren;
- Horton, Helen;
- Jaspan, Heather;
- Gervassi, Ana
Publication type:
Article
T-SPOT.TB Reactivity in Southern African Children With and Without in Utero Human Immunodeficiency Virus Exposure.
Published in:
Clinical Infectious Diseases, 2023, v. 77, n. 8, p. 1133, doi. 10.1093/cid/ciad356
By:
- Iwase, Saori C;
- Edlefsen, Paul T;
- Bhebhe, Lynnette;
- Motsumi, Kesego;
- Moyo, Sikhulile;
- Happel, Anna-Ursula;
- Shao, Danica;
- Mmasa, Nicholas;
- Schenkel, Sara;
- Gasper, Melanie A;
- Dubois, Melanie;
- Files, Megan A;
- Seshadri, Chetan;
- Duffy, Fergal;
- Aitchison, John;
- Netea, Mihai G;
- Jao, Jennifer;
- Cameron, Donald W;
- Gray, Clive M;
- Jaspan, Heather B
Publication type:
Article
Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2.
Published in:
Nature, 2012, v. 490, n. 7420, p. 417, doi. 10.1038/nature11519
By:
- Rolland, Morgane;
- Edlefsen, Paul T.;
- Larsen, Brendan B.;
- Tovanabutra, Sodsai;
- Sanders-Buell, Eric;
- Hertz, Tomer;
- deCamp, Allan C.;
- Carrico, Chris;
- Menis, Sergey;
- Magaret, Craig A.;
- Ahmed, Hasan;
- Juraska, Michal;
- Chen, Lennie;
- Konopa, Philip;
- Nariya, Snehal;
- Stoddard, Julia N.;
- Wong, Kim;
- Zhao, Hong;
- Deng, Wenjie;
- Maust, Brandon S.
Publication type:
Article
Early cellular innate immune responses drive Zika viral persistence and tissue tropism in pigtail macaques.
Published in:
Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-05826-w
By:
- O'Connor, Megan A.;
- Tisoncik-Go, Jennifer;
- Lewis, Thomas B.;
- Miller, Charlene J.;
- Bratt, Debra;
- Moats, Cassie R.;
- Edlefsen, Paul T.;
- Smedley, Jeremy;
- Klatt, Nichole R.;
- Gale Jr, Michael;
- Fuller, Deborah Heydenburg
Publication type:
Article
Evaluation of the immunogenicity and efficacy of an rVSV vaccine against Zika virus infection in macaca nemestrina.
Published in:
Frontiers in Virology, 2023, p. 1, doi. 10.3389/fviro.2023.1108420
By:
- Tisoncik-Go, Jennifer;
- Voss, Kathleen M.;
- Lewis, Thomas B.;
- Muruato, Antonio E.;
- Kuller, LaRene;
- Finn, Eric E.;
- Betancourt, Dillon;
- Wangari, Solomon;
- Ahrens, Joel;
- Iwayama, Naoto;
- Grant, Richard F.;
- Murnane, Robert D.;
- Edlefsen, Paul T.;
- Fuller, Deborah H.;
- Barber, Glen N.;
- Gale Jr, Michael;
- O'Connor, Megan A.
Publication type:
Article
Cytomegalovirus vectors expressing Plasmodium knowlesi antigens induce immune responses that delay parasitemia upon sporozoite challenge.
Published in:
PLoS ONE, 2019, v. 14, n. 1, p. 1, doi. 10.1371/journal.pone.0210252
By:
- Hansen, Scott G.;
- Womack, Jennie;
- Scholz, Isabel;
- Renner, Andrea;
- Edgel, Kimberly A.;
- Xu, Guangwu;
- Ford, Julia C.;
- Grey, Mikayla;
- St. Laurent, Brandyce;
- Turner, John M.;
- Planer, Shannon;
- Legasse, Al W.;
- Richie, Thomas L.;
- Aguiar, Joao C.;
- Axthelm, Michael K.;
- Villasante, Eileen D.;
- Weiss, Walter;
- Edlefsen, Paul T.;
- Picker, Louis J.;
- Früh, Klaus
Publication type:
Article
Transposon identification using profile HMMs.
Published in:
BMC Genomics, 2010, v. 11, p. 1, doi. 10.1186/1471-2164-11-S1-S10
By:
- Edlefsen, Paul T.;
- Liu, Jun S.
Publication type:
Article
RV144 HIV-1 vaccination impacts post-infection antibody responses.
Published in:
PLoS Pathogens, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.ppat.1009101
By:
- Mdluli, Thembi;
- Jian, Ningbo;
- Slike, Bonnie;
- Paquin-Proulx, Dominic;
- Donofrio, Gina;
- Alrubayyi, Aljawharah;
- Gift, Syna;
- Grande, Rebecca;
- Bryson, Mary;
- Lee, Anna;
- Dussupt, Vincent;
- Mendez-Riveria, Letzibeth;
- Sanders-Buell, Eric;
- Chenine, Agnès-Laurence;
- Tran, Ursula;
- Li, Yifan;
- Brown, Eric;
- Edlefsen, Paul T.;
- O'Connell, Robert;
- Gilbert, Peter
Publication type:
Article
Molecular dating and viral load growth rates suggested that the eclipse phase lasted about a week in HIV-1 infected adults in East Africa and Thailand.
Published in:
PLoS Pathogens, 2020, v. 16, n. 2, p. 1, doi. 10.1371/journal.ppat.1008179
By:
- Rolland, Morgane;
- Tovanabutra, Sodsai;
- Dearlove, Bethany;
- Li, Yifan;
- Owen, Christopher L.;
- Lewitus, Eric;
- Sanders-Buell, Eric;
- Bose, Meera;
- O'Sullivan, AnneMarie;
- Rossenkhan, Raabya;
- Labuschagne, Jan Phillipus Lourens;
- Edlefsen, Paul T.;
- Reeves, Daniel B.;
- Kijak, Gustavo;
- Miller, Shana;
- Poltavee, Kultida;
- Lee, Jenica;
- Bonar, Lydia;
- Harbolick, Elizabeth;
- Ahani, Bahar
Publication type:
Article
Prediction of VRC01 neutralization sensitivity by HIV-1 gp160 sequence features.
Published in:
PLoS Computational Biology, 2019, v. 15, n. 4, p. 1, doi. 10.1371/journal.pcbi.1006952
By:
- Magaret, Craig A.;
- Benkeser, David C.;
- Williamson, Brian D.;
- Borate, Bhavesh R.;
- Carpp, Lindsay N.;
- Georgiev, Ivelin S.;
- Setliff, Ian;
- Dingens, Adam S.;
- Simon, Noah;
- Carone, Marco;
- Simpkins, Christopher;
- Montefiori, David;
- Alter, Galit;
- Yu, Wen-Han;
- Juraska, Michal;
- Edlefsen, Paul T.;
- Karuna, Shelly;
- Mgodi, Nyaradzo M.;
- Edugupanti, Srilatha;
- Gilbert, Peter B.
Publication type:
Article
SieveSifter: a web-based tool for visualizing the sieve analyses of HIV-1 vaccine efficacy trials.
Published in:
Bioinformatics, 2017, v. 33, n. 15, p. 2386, doi. 10.1093/bioinformatics/btx168
By:
- Fiore-Gartland, Andrew;
- Kullman, Nicholas;
- Decamp, Allan C.;
- Clenaghan, Graham;
- Wayne Yang;
- Magaret, Craig A.;
- Edlefsen, Paul T.;
- Gilbert, Peter B.
Publication type:
Article
Sieve analysis of breakthrough HIV-1 sequences in HVTN 505 identifies vaccine pressure targeting the CD4 binding site of Env-gp120.
Published in:
PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0185959
By:
- Decamp, Allan C.;
- Rolland, Morgane;
- Edlefsen, Paul T.;
- Sanders-Buell, Eric;
- Hall, Breana;
- Magaret, Craig A.;
- Fiore-Gartland, Andrew J.;
- Juraska, Michal;
- Carpp, Lindsay N.;
- Karuna, Shelly T.;
- Bose, Meera;
- Lepore, Steven;
- Miller, Shana;
- O'sullivan, Annemarie;
- Poltavee, Kultida;
- Bai, Hongjun;
- Dommaraju, Kalpana;
- Zhao, Hong;
- Wong, Kim;
- Chen, Lennie
Publication type:
Article
Leaky Vaccines Protect Highly Exposed Recipients at a Lower Rate: Implications for Vaccine Efficacy Estimation and Sieve Analysis.
Published in:
Computational & Mathematical Methods in Medicine, 2014, p. 1, doi. 10.1155/2014/813789
By:
- Edlefsen, Paul T.
Publication type:
Article

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