Works by Edenhofer, Frank

Results: 40

Need for high-resolution Genetic Analysis in iPSC: Results and Lessons from the ForIPS Consortium.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-35506-0

By:

Popp, Bernt;
Krumbiegel, Mandy;
Grosch, Janina;
Sommer, Annika;
Uebe, Steffen;
Kohl, Zacharias;
Plötz, Sonja;
Farrell, Michaela;
Trautmann, Udo;
Kraus, Cornelia;
Ekici, Arif B.;
Asadollahi, Reza;
Regensburger, Martin;
Günther, Katharina;
Rauch, Anita;
Edenhofer, Frank;
Winkler, Jürgen;
Winner, Beate;
Reis, André

Publication type:

Article

Development of a bioreactor system for pre‐endothelialized cardiac patch generation with enhanced viscoelastic properties by combined collagen I compression and stromal cell culture.

Published in:

Journal of Tissue Engineering & Regenerative Medicine, 2020, v. 14, n. 12, p. 1749, doi. 10.1002/term.3129

By:

Krziminski, Carolin;
Kammann, Sebastian;
Hansmann, Jan;
Edenhofer, Frank;
Dandekar, Gudrun;
Walles, Heike;
Leistner, Marcus

Publication type:

Article

Scalable stirred suspension culture for the generation of billions of human induced pluripotent stem cells using single‐use bioreactors.

Published in:

Journal of Tissue Engineering & Regenerative Medicine, 2018, v. 12, n. 2, p. e1076, doi. 10.1002/term.2435

By:

Kwok, Chee Keong;
Ueda, Yuichiro;
Kadari, Asifiqbal;
Günther, Katharina;
Ergün, Süleyman;
Heron, Antoine;
Schnitzler, Aletta C.;
Rook, Martha;
Edenhofer, Frank

Publication type:

Article

Serotonin-specific neurons differentiated from human iPSCs form distinct subtypes with synaptic protein assembly.

Published in:

Journal of Neural Transmission, 2021, v. 128, n. 2, p. 225, doi. 10.1007/s00702-021-02303-5

By:

Jansch, Charline;
Ziegler, Georg C.;
Forero, Andrea;
Gredy, Sina;
Wäldchen, Sina;
Vitale, Maria Rosaria;
Svirin, Evgeniy;
Zöller, Johanna E. M.;
Waider, Jonas;
Günther, Katharina;
Edenhofer, Frank;
Sauer, Markus;
Wischmeyer, Erhard;
Lesch, Klaus-Peter

Publication type:

Article

Merging Fields: Stem Cells in Neurogenesis, Transplantation, and Disease Modeling.

Published in:

Brain Pathology, 2006, v. 16, n. 2, p. 155, doi. 10.1111/j.1750-3639.2006.00010.x

By:

Scheffler, Björn;
Edenhofer, Frank;
Brüstle, Oliver

Publication type:

Article

MicroRNAs Are Indispensable for Reprogramming Mouse Embryonic Fibroblasts into Induced Stem Cell-Like Cells.

Published in:

PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0039239

By:

Byeong-Moo Kim;
Thier, Marc-Christian;
Sangnam Oh;
Sherwood, Richard;
Kanellopoulou, Chryssa;
Edenhofer, Frank;
Choi, Michael Y.

Publication type:

Article

Sox2 Is Essential for Formation of Trophectoderm in the Preimplantation Embryo.

Published in:

PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0013952

By:

Keramari, Maria;
Razavi, Janet;
Ingman, Karen A.;
Patsch, Christoph;
Edenhofer, Frank;
Ward, Christopher M.;
Kimber, Susan J.

Publication type:

Article

Cargo-dependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells.

Published in:

FASEB Journal, 2006, v. 20, n. 11, p. 1775, doi. 10.1096/fj.05-5523com

By:

Tünnemann, Gisela;
Martin, Robert M.;
Haupt, Simone;
Patsch, Christoph;
Edenhofer, Frank;
Cardoso, M. Cristina

Publication type:

Article

A novel conditional <italic>Aire</italic> allele enables cell‐specific ablation of the immune tolerance regulator Aire.

Published in:

European Journal of Immunology, 2018, v. 48, n. 3, p. 546, doi. 10.1002/eji.201747267

By:

Dobeš, Jan;
Edenhofer, Frank;
Vobořil, Matouš;
Brabec, Tomáš;
Dobešová, Martina;
Čepková, Adéla;
Klein, Ludger;
Rajewsky, Klaus;
Filipp, Dominik

Publication type:

Article

BMP/SMAD Pathway Promotes Neurogenesis of Midbrain Dopaminergic Neurons In Vivo and in Human Induced Pluripotent and Neural Stem Cells.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 7, p. 1662, doi. 10.1523/JNEUROSCI.1540-17.2018

By:

Jovanovic, Vukasin M.;
Salti, Ahmad;
Tilleman, Hadas;
Zega, Ksenija;
Jukic, Marin M.;
Hongyan Zou;
Friede, Roland H.;
Prakash, Nilima;
Blaess, Sandra;
Edenhofer, Frank;
Brodski, Claude

Publication type:

Article

Modeling early phenotypes of Parkinson's disease by age-induced midbrain-striatum assembloids.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07273-4

By:

Barmpa, Kyriaki;
Saraiva, Claudia;
Lopez-Pigozzi, Diego;
Gomez-Giro, Gemma;
Gabassi, Elisa;
Spitz, Sarah;
Brandauer, Konstanze;
Rodriguez Gatica, Juan E.;
Antony, Paul;
Robertson, Graham;
Sabahi-Kaviani, Rahman;
Bellapianta, Alessandro;
Papastefanaki, Florentia;
Luttge, Regina;
Kubitscheck, Ulrich;
Salti, Ahmad;
Ertl, Peter;
Bortolozzi, Mario;
Matsas, Rebecca;
Edenhofer, Frank

Publication type:

Article

ADHD‐associated PARK2 copy number variants: A pilot study on gene expression and effects of supplementary deprivation in patient‐derived cell lines.

Published in:

American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2022, v. 189, n. 7/8, p. 257, doi. 10.1002/ajmg.b.32918

By:

Radtke, Franziska;
Palladino, Viola Stella;
McNeill, Rhiannon V.;
Chiocchetti, Andreas G.;
Haslinger, Denise;
Leyh, Matthias;
Gersic, Danijel;
Frank, Markus;
Grünewald, Lena;
Klebe, Stephan;
Brüstle, Oliver;
Günther, Katharina;
Edenhofer, Frank;
Kranz, Thorsten M.;
Reif, Andreas;
Kittel‐Schneider, Sarah

Publication type:

Article

Automated selection and harvesting of pluripotent stem cell colonies.

Published in:

Biotechnology & Applied Biochemistry, 2012, v. 59, n. 2, p. 77, doi. 10.1002/bab.1014

By:

Haupt, Simone;
Grützner, Jan;
Thier, Marc-Christian;
Kallweit, Tobias;
Rath, Barbara Helen;
Laufenberg, Iris;
Forgber, Michael;
Eberhardt, Jens;
Edenhofer, Frank;
Brüstle, Oliver

Publication type:

Article

A genome-scale map of DNA methylation turnover identifies site-specific dependencies of DNMT and TET activity.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16354-x

By:

Ginno, Paul Adrian;
Gaidatzis, Dimos;
Feldmann, Angelika;
Hoerner, Leslie;
Imanci, Dilek;
Burger, Lukas;
Zilbermann, Frederic;
Peters, Antoine H. F. M.;
Edenhofer, Frank;
Smallwood, Sébastien A.;
Krebs, Arnaud R.;
Schübeler, Dirk

Publication type:

Article

Transcription factor-based modulation of neural stem cell differentiation using direct protein transduction.

Published in:

Cellular & Molecular Life Sciences, 2010, v. 67, n. 14, p. 2439, doi. 10.1007/s00018-010-0347-1

By:

Stock, Kristin;
Nolden, Lars;
Edenhofer, Frank;
Quandel, Tamara;
Brüstle, Oliver

Publication type:

Article

Deciphering the stem cell machinery as a basis for understanding the molecular mechanism underlying reprogramming.

Published in:

Cellular & Molecular Life Sciences, 2009, v. 66, n. 21, p. 3403, doi. 10.1007/s00018-009-0095-2

By:

Bosnali, Manal;
Münst, Bernhard;
Thier, Marc;
Edenhofer, Frank

Publication type:

Article

MTOR Is Essential for Growth and Proliferation in Early Mouse Embryos and Embryonic Stem Cells.

Published in:

Molecular & Cellular Biology, 2004, v. 24, n. 15, p. 6710, doi. 10.1128/MCB.24.15.6710-6718.2004

By:

Murakami, Mirei;
Ichisaka, Tomoko;
Maeda, Mitsuyo;
Oshiro, Noriko;
Hara, Kenta;
Edenhofer, Frank;
Kiyama, Hiroshi;
Yonezawa, Kazuyoshi;
Yamanaka, Shinya

Publication type:

Article

Efficient in vitro and in vivo excision of floxed sequences with a high-capacity adenoviral vector expressing CRE recombinase.

Published in:

Genesis: The Journal of Genetics & Development, 2002, v. 33, n. 3, p. 119, doi. 10.1002/gene.10099

By:

Badorf, Michael;
Edenhofer, Frank;
Dries, Volker;
Kochanek, Stefan;
Schiedner, Gudrun

Publication type:

Article

Targeting α-Synuclein in Parkinson's Disease by Induced Pluripotent Stem Cell Models.

Published in:

Frontiers in Neurology, 2022, v. 12, p. 1, doi. 10.3389/fneur.2021.786835

By:

Spathopoulou, Angeliki;
Edenhofer, Frank;
Fellner, Lisa

Publication type:

Article

Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain.

Published in:

Frontiers in Cellular Neuroscience, 2017, p. 1, doi. 10.3389/fncel.2017.00307

By:

Forero, Andrea;
Rivero, Olga;
Wäldchen, Sina;
Ku, Hsing-Ping;
Kiser, Dominik P.;
Gärtner, Yvonne;
Pennington, Laura S.;
Waider, Jonas;
Gaspar, Patricia;
Jansch, Charline;
Edenhofer, Frank;
Resink, Thérèse J.;
Blum, Robert;
Sauer, Markus;
Lesch, Klaus-Peter

Publication type:

Article

Chemistry and Molecular Biology of Transmissible Spongiform Encephalopathies.

Published in:

Angewandte Chemie International Edition, 1997, v. 36, n. 16, p. 1674, doi. 10.1002/anie.199716741

By:

Edenhofer, Frank;
Weiss, Stefan;
Winnacker, Ernst-Ludwig;
Famulok, Michael

Publication type:

Article

Next‐generation disease modeling with direct conversion: a new path to old neurons.

Published in:

FEBS Letters, 2019, v. 593, n. 23, p. 3316, doi. 10.1002/1873-3468.13678

By:

Traxler, Larissa;
Edenhofer, Frank;
Mertens, Jerome

Publication type:

Article

Take the shortcut – direct conversion of somatic cells into induced neural stem cells and their biomedical applications.

Published in:

FEBS Letters, 2019, v. 593, n. 23, p. 3353, doi. 10.1002/1873-3468.13656

By:

Erharter, Anita;
Rizzi, Sandra;
Mertens, Jerome;
Edenhofer, Frank

Publication type:

Article

Site-specific recombination in human embryonic stem cells induced by cell-permeant Cre recombinase.

Published in:

Nature Methods, 2006, v. 3, n. 6, p. 461, doi. 10.1038/nmeth884

By:

Nolden, Lars;
Edenhofer, Frank;
Haupt, Simone;
Koch, Philipp;
Wunderlich, F. Thomas;
Siemen, Henrike;
Brüstle, Oliver

Publication type:

Article

Energy Metabolism Disturbances in Cell Models of PARK2 CNV Carriers with ADHD.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 12, p. 4092, doi. 10.3390/jcm9124092

By:

Palladino, Viola Stella;
Chiocchetti, Andreas G.;
Frank, Lukas;
Haslinger, Denise;
McNeill, Rhiannon;
Radtke, Franziska;
Till, Andreas;
Haupt, Simone;
Brüstle, Oliver;
Günther, Katharina;
Edenhofer, Frank;
Hoffmann, Per;
Reif, Andreas;
Kittel-Schneider, Sarah

Publication type:

Article

A thermoresponsive and chemically defined hydrogel for long-term culture of human embryonic stem cells.

Published in:

Nature Communications, 2013, v. 4, n. 1, p. 1335, doi. 10.1038/ncomms2341

By:

Zhang, Rong;
Mjoseng, Heidi K.;
Hoeve, Marieke A.;
Bauer, Nina G.;
Pells, Steve;
Besseling, Rut;
Velugotla, Srinivas;
Tourniaire, Guilhem;
Kishen, Ria E. B.;
Tsenkina, Yanina;
Armit, Chris;
Duffy, Cairnan R. E.;
Helfen, Martina;
Edenhofer, Frank;
de Sousa, Paul A.;
Bradley, Mark

Publication type:

Article

Emerging Role of miR-21-5p in Neuron–Glia Dysregulation and Exosome Transfer Using Multiple Models of Alzheimer's Disease.

Published in:

Cells (2073-4409), 2022, v. 11, n. 21, p. 3377, doi. 10.3390/cells11213377

By:

Garcia, Gonçalo;
Pinto, Sara;
Ferreira, Sofia;
Lopes, Daniela;
Serrador, Maria João;
Fernandes, Adelaide;
Vaz, Ana Rita;
Mendonça, Alexandre de;
Edenhofer, Frank;
Malm, Tarja;
Koistinaho, Jari;
Brites, Dora

Publication type:

Article

Autophagy in α-Synucleinopathies—An Overstrained System.

Published in:

Cells (2073-4409), 2021, v. 10, n. 11, p. 3143, doi. 10.3390/cells10113143

By:

Fellner, Lisa;
Gabassi, Elisa;
Haybaeck, Johannes;
Edenhofer, Frank

Publication type:

Article

High Glycolytic Activity Enhances Stem Cell Reprogramming of Fahd1-KO Mouse Embryonic Fibroblasts.

Published in:

Cells (2073-4409), 2021, v. 10, n. 8, p. 2040, doi. 10.3390/cells10082040

By:

Salti, Ahmad;
Etemad, Solmaz;
Cubero, Marta Suarez;
Albertini, Eva;
Kovacs-Szalka, Beata;
Holzknecht, Max;
Cappuccio, Elia;
Cavinato, Maria;
Edenhofer, Frank;
Jansen Dürr, Pidder

Publication type:

Article

Excision of viral reprogramming cassettes by Cre protein transduction enables rapid, robust and efficient derivation of transgene-free human induced pluripotent stem cells.

Published in:

Stem Cell Research & Therapy, 2014, v. 5, n. 2, p. 1, doi. 10.1186/scrt435

By:

Kadari, Asifiqbal;
Min Lu;
Ming Li;
Sekaran, Thileepan;
Thummer, Rajkumar P.;
Guyette, Naomi;
Vi Chu;
Edenhofer, Frank

Publication type:

Article

Cellular Reprogramming Employing Recombinant Sox2 Protein.

Published in:

Stem Cells International, 2012, p. 1, doi. 10.1155/2012/549846

By:

Thier, Marc;
Münst, Bernhard;
Mielke, Stephanie;
Edenhofer, Frank

Publication type:

Article

Abrogation of Gap Junctional Communication in ES Cells Results in a Disruption of Primitive Endoderm Formation in Embryoid Bodies.

Published in:

Stem Cells, 2017, v. 35, n. 4, p. 859, doi. 10.1002/stem.2545

By:

Wörsdörfer, Philipp;
Bosen, Felicitas;
Gebhardt, Martina;
Russ, Nicole;
Zimmermann, Katrin;
Komla Kessie, David;
Sekaran, Thileepan;
Egert, Angela;
Ergün, Süleyman;
Schorle, Hubert;
Pfeifer, Alexander;
Edenhofer, Frank;
Willecke, Klaus

Publication type:

Article

Inhibition of Notch Signaling in Human Embryonic Stem Cell-Derived Neural Stem Cells Delays Gl/S Phase Transition and Accelerates Neuronal Differentiation In Vitro and In Vivo.

Published in:

Stem Cells, 2010, v. 28, n. 5, p. 955, doi. 10.1002/stem.408

By:

Borghese, Lodovica;
Dolezalova, Dasa;
Opitz, Thoralf;
Hauft, Simone;
Leinhaas, Anke;
Steinfarz, Barbara;
Koch, Philipp;
Edenhofer, Frank;
Hampl, Ales;
Brüstle, Oliver

Publication type:

Article

Engineering Cell-Permeant FLP Recombinase for Tightly Controlled Inducible and Reversible Overexpression in Embryonic Stem Cells.

Published in:

Stem Cells, 2010, v. 28, n. 5, p. 894, doi. 10.1002/stem.417

By:

Patsch, Christoph;
Peitz, Micahel;
Otte, David M.;
Kesskler, Daniela;
Jungverdorben, Johannes;
Wunderlich, Frank Thomas;
Brüstle, Oliver;
Zimmer, Andreas;
Edenhofer, Frank

Publication type:

Article

Stage-Specific Conditional Mutagenesis in Mouse Embryonic Stem Cell-Derived Neural Cells and Postmitotic Neurons by Direct Delivery of Biologically Active Cre Recombinase.

Published in:

Stem Cells, 2007, v. 25, n. 1, p. 181, doi. 10.1634/stemcells.2006-0371

By:

HAUPT, SIMONE;
EDENHOFER, FRANK;
PEITZ, MICHAEL;
LEINHAAS, ANKE;
BRÜSTLE, OLIVER

Publication type:

Article

Low-density lipoprotein receptor-related protein 1 is a novel modulator of radial glia stem cell proliferation, survival, and differentiation.

Published in:

Glia (0894-1491), 2016, v. 64, n. 8, p. 1363, doi. 10.1002/glia.23009

By:

Safina, Dina;
Schlitt, Frederik;
Romeo, Ramona;
Pflanzner, Thorsten;
Pietrzik, Claus U.;
Narayanaswami, Vasanthy;
Edenhofer, Frank;
Faissner, Andreas

Publication type:

Article

Transplantation of induced neural stem cells (iNSCs) into chronically demyelinated corpus callosum ameliorates motor deficits.

Published in:

Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00960-3

By:

Sullivan, Genevieve M.;
Knutsen, Andrew K.;
Peruzzotti-Jametti, Luca;
Korotcov, Alexandru;
Bosomtwi, Asamoah;
Dardzinski, Bernard J.;
Bernstock, Joshua D.;
Rizzi, Sandra;
Edenhofer, Frank;
Pluchino, Stefano;
Armstrong, Regina C.

Publication type:

Article

Quantification of cell fusion events human breast cancer cells and breast epithelial cells using a Cre-LoxP-based double fluorescence reporter system.

Published in:

Cellular & Molecular Life Sciences, 2015, v. 72, n. 19, p. 3769, doi. 10.1007/s00018-015-1910-6

By:

Mohr, Marieke;
Tosun, Songül;
Arnold, Wolfgang;
Edenhofer, Frank;
Zänker, Kurt;
Dittmar, Thomas

Publication type:

Article

Generation of transducible versions of transcription factors Oct4 and Sox2.

Published in:

Biological Chemistry, 2008, v. 389, n. 7, p. 851, doi. 10.1515/BC.2008.106

By:

Bosnali, Manal;
Edenhofer, Frank

Publication type:

Article

The promise of genetic screens in human in vitro brain models.

Published in:

Biological Chemistry, 2024, v. 405, n. 1, p. 13, doi. 10.1515/hsz-2023-0174

By:

Beirute-Herrera, Julianne;
López-Amo Calvo, Beatriz;
Edenhofer, Frank;
Esk, Christopher

Publication type:

Article