Works by Edagwa, Benson

Results: 25

LONG-ACTING NANOFORMULATIONS REDUCE DOLUTEGRAVIR EXPOSURE TO EMBRYO BRAIN.

Published in:

Topics in Antiviral Medicine, 2023, v. 31, n. 2, p. 313

By:

Foster, Emma G.;
Edagwa, Benson;
Gendelman, Howard E.;
Bade, Aditya

Publication type:

Article

ULTRA-LONG-ACTING BICTEGRAVIR NANOFORMULATIONS.

Published in:

Topics in Antiviral Medicine, 2023, v. 31, n. 2, p. 212

By:

Nayan, Mohammad Ullah;
Das, Srijanee;
Sillman, Brady;
Hanson, Brandon;
Byrareddy, Siddappa;
Gendelman, Howard E.;
Edagwa, Benson

Publication type:

Article

Elevated Methylglyoxal: An Elusive Risk Factor Responsible for Early-Onset Cardiovascular Diseases in People Living with HIV-1 Infection.

Published in:

Viruses (1999-4915), 2025, v. 17, n. 4, p. 547, doi. 10.3390/v17040547

By:

Ramasamy, Mahendran;
Venn, Zachary L.;
Alomar, Fadhel A.;
Namvaran, Ali;
Edagwa, Benson;
Gorantla, Santhi;
Bidasee, Keshore R.

Publication type:

Article

Transformation of tenofovir into stable ProTide nanocrystals with long-acting pharmacokinetic profiles.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25690-5

By:

Cobb, Denise A.;
Smith, Nathan;
Deodhar, Suyash;
Bade, Aditya N.;
Gautam, Nagsen;
Shetty, Bhagya Laxmi Dyavar;
McMillan, JoEllyn;
Alnouti, Yazen;
Cohen, Samuel M.;
Gendelman, Howard E.;
Edagwa, Benson

Publication type:

Article

Lipophilic nanocrystal prodrug-release defines the extended pharmacokinetic profiles of a year-long cabotegravir.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23668-x

By:

Gautam, Nagsen;
McMillan, JoEllyn M.;
Kumar, Devendra;
Bade, Aditya N.;
Pan, Qiaoyu;
Kulkarni, Tanmay A.;
Li, Wenkuan;
Sillman, Brady;
Smith, Nathan A.;
Shetty, Bhagya L. Dyavar;
Szlachetka, Adam;
Edagwa, Benson J.;
Gendelman, Howard E.;
Alnouti, Yazen

Publication type:

Article

Polymer Delivery Systems for Long-Acting Antiretroviral Drugs.

Published in:

Pharmaceutics, 2024, v. 16, n. 2, p. 183, doi. 10.3390/pharmaceutics16020183

By:

Nayan, Mohammad Ullah;
Panja, Sudipta;
Sultana, Ashrafi;
Zaman, Lubaba A.;
Vora, Lalitkumar K.;
Sillman, Brady;
Gendelman, Howard E.;
Edagwa, Benson

Publication type:

Article

Prodrug Therapies for Infectious and Neurodegenerative Diseases.

Published in:

Pharmaceutics, 2022, v. 14, n. 3, p. 518, doi. 10.3390/pharmaceutics14030518

By:

Markovic, Milica;
Deodhar, Suyash;
Machhi, Jatin;
Yeapuri, Pravin;
Saleh, Maamoon;
J. Edagwa, Benson;
Mosley, Rodney Lee;
Gendelman, Howard E.

Publication type:

Article

Autophagy facilitates macrophage depots of sustained-release nanoformulated antiretroviral drugs.

Published in:

2017

By:

Gnanadhas, Divya Prakash;
Dash, Prasanta K.;
Sillman, Brady;
Bade, Aditya N.;
Zhiyi Lin;
Palandri, Diana L.;
Gautam, Nagsen;
Alnouti, Yazen;
Gelbard, Harris A.;
McMillan, JoEllyn;
Mosley, R. Lee;
Edagwa, Benson;
Gendelman, Howard E.;
Gorantla, Santhi;
Lin, Zhiyi

Publication type:

journal article

HIV-Tat Exacerbates the Actions of Atazanavir, Efavirenz, and Ritonavir on Cardiac Ryanodine Receptor (RyR2).

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 274, doi. 10.3390/ijms24010274

By:

Alomar, Fadhel A.;
Tian, Chengju;
Bidasee, Sean R.;
Venn, Zachary L.;
Schroder, Evan;
Palermo, Nicholas Y.;
AlShabeeb, Mohammad;
Edagwa, Benson J.;
Payne, Jason J.;
Bidasee, Keshore R.

Publication type:

Article

EcoHIV infection of mice establishes latent viral reservoirs in T cells and active viral reservoirs in macrophages that are sufficient for induction of neurocognitive impairment.

Published in:

PLoS Pathogens, 2018, v. 14, n. 6, p. 1, doi. 10.1371/journal.ppat.1007061

By:

Gu, Chao-Jiang;
Borjabad, Alejandra;
Hadas, Eran;
Kelschenbach, Jennifer;
Kim, Boe-Hyun;
Chao, Wei;
Arancio, Ottavio;
Suh, Jin;
Polsky, Bruce;
McMillan, JoEllyn;
Edagwa, Benson;
Gendelman, Howard E.;
Potash, Mary Jane;
Volsky, David J.

Publication type:

Article

Challenges in ultralong-acting formulation development: eyes on buprenorphine.

Published in:

2023

By:

Deodhar, Suyash;
Edagwa, Benson;
Sillman, Brady

Publication type:

Letter to the Editor

Humanized Mice for Infectious and Neurodegenerative disorders.

Published in:

Retrovirology, 2021, v. 18, n. 1, p. 1, doi. 10.1186/s12977-021-00557-1

By:

Dash, Prasanta K.;
Gorantla, Santhi;
Poluektova, Larisa;
Hasan, Mahmudul;
Waight, Emiko;
Zhang, Chen;
Markovic, Milica;
Edagwa, Benson;
Machhi, Jatin;
Olson, Katherine E.;
Wang, Xinglong;
Mosley, R. Lee;
Kevadiya, Bhavesh;
Gendelman, Howard E.

Publication type:

Article

A mature macrophage is a principal HIV-1 cellular reservoir in humanized mice after treatment with long acting antiretroviral therapy.

Published in:

Retrovirology, 2017, v. 14, p. 1, doi. 10.1186/s12977-017-0344-7

By:

Araínga, Mariluz;
Edagwa, Benson;
Mosley, R. Lee;
Poluektova, Larisa Y.;
Gorantla, Santhi;
Gendelman, Howard E.

Publication type:

Article

Long-acting approaches for delivery of antiretroviral drugs for prevention and treatment of HIV: a review of recent research.

Published in:

Expert Opinion on Drug Delivery, 2020, v. 17, n. 9, p. 1227, doi. 10.1080/17425247.2020.1783233

By:

Cobb, Denise A.;
Smith, Nathan A.;
Edagwa, Benson J.;
McMillan, JoEllyn M.

Publication type:

Article

Long-acting slow effective release antiretroviral therapy.

Published in:

Expert Opinion on Drug Delivery, 2017, v. 14, n. 11, p. 1281, doi. 10.1080/17425247.2017.1288212

By:

Edagwa, Benson;
McMillan, JoEllyn;
Sillman, Brady;
Gendelman, Howard E

Publication type:

Article

Chronic Hepatitis B Infection: New Approaches towards Cure.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 8, p. 1208, doi. 10.3390/biom13081208

By:

Ogunnaike, Mojisola;
Das, Srijanee;
Raut, Samiksha S.;
Sultana, Ashrafi;
Nayan, Mohammad Ullah;
Ganesan, Murali;
Edagwa, Benson J.;
Osna, Natalia A.;
Poluektova, Larisa Y.

Publication type:

Article

Creation of a long-acting nanoformulated dolutegravir.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-02885-x

By:

Sillman, Brady;
Bade, Aditya N.;
Dash, Prasanta K.;
Bhargavan, Biju;
Kocher, Ted;
Mathews, Saumi;
Hang Su;
Kanmogne, Georgette D.;
Poluektova, Larisa Y.;
Gorantla, Santhi;
McMillan, JoEllyn;
Gautam, Nagsen;
Alnouti, Yazen;
Edagwa, Benson;
Gendelman, Howard E.

Publication type:

Article

Long-acting antituberculous therapeutic nanoparticles target macrophage endosomes.

Published in:

FASEB Journal, 2014, v. 28, n. 12, p. 5071, doi. 10.1096/fj.14-255786

By:

Edagwa, Benson J.;
Dongwei Guo;
Puligujja, Pavan;
Han Chen;
McMillan, JoEllyn;
Xinming Liu;
Gendelman, Howard E.;
Narayanasamy, Prabagaran

Publication type:

Article

Long-acting dolutegravir formulations prevent neurodevelopmental impairments in a mouse model.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1294579

By:

Foster, Emma G.;
Sillman, Brady;
Yutong Liu;
Summerlin, Micah;
Kumar, Vikas;
Sajja, Balasrinivasa R.;
Cassidy, Adam R.;
Edagwa, Benson;
Gendelman, Howard E.;
Bade, Aditya N.

Publication type:

Article

Cellular Responses and Tissue Depots for Nanoformulated Antiretroviral Therapy.

Published in:

PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0145966

By:

Martinez-Skinner, Andrea L.;
Araínga, Mariluz A.;
Puligujja, Pavan;
Palandri, Diana L.;
Baldridge, Hannah M.;
Edagwa, Benson J.;
McMillan, JoEllyn M.;
Mosley, R. Lee;
Gendelman, Howard E.

Publication type:

Article

Dolutegravir Inhibition of Matrix Metalloproteinases Affects Mouse Neurodevelopment.

Published in:

Molecular Neurobiology, 2021, v. 58, n. 11, p. 5703, doi. 10.1007/s12035-021-02508-5

By:

Bade, Aditya N.;
McMillan, JoEllyn M.;
Liu, Yutong;
Edagwa, Benson J.;
Gendelman, Howard E.

Publication type:

Article

Nanoformulated Antiretroviral Therapy Attenuates Brain Metabolic Oxidative Stress.

Published in:

Molecular Neurobiology, 2019, v. 56, n. 4, p. 2896, doi. 10.1007/s12035-018-1273-8

By:

Montenegro-Burke, J. Rafael;
Woldstad, Christopher J.;
Fang, Mingliang;
Bade, Aditya N.;
McMillan, JoEllyn;
Edagwa, Benson;
Boska, Michael D.;
Gendelman, Howard E.;
Siuzdak, Gary

Publication type:

Article

Synthesis and characterization of a long-acting emtricitabine prodrug nanoformulation.

Published in:

International Journal of Nanomedicine, 2019, v. 14, p. 6231, doi. 10.2147/IJN.S215447

By:

Ibrahim, Ibrahim M;
Bade, Aditya N;
Lin, Zhiyi;
Soni, Dhruvkumar;
Wojtkiewicz, Melinda;
Shetty, Bhagya Laxmi Dyavar;
Gautam, Nagsen;
McMillan, JoEllyn M;
Alnouti, Yazen;
Edagwa, Benson J;
Gendelman, Howard E

Publication type:

Article

Magnetic resonance imaging of folic acid-coated magnetite nanoparticles reflects tissue biodistribution of long-acting antiretroviral therapy.

Published in:

International Journal of Nanomedicine, 2015, v. 10, p. 3779, doi. 10.2147/IJN.S83279

By:

Tianyuzi Li;
Gendelman, Howard E.;
Gang Zhang;
Puligujja, Pavan;
McMillan, JoEllyn M.;
Bronich, Tatiana K.;
Edagwa, Benson;
Xin-Ming Liu;
Boska, Michael D.

Publication type:

Article

Oral antivirals for the prevention and treatment of SARS-CoV-2 infection.

Published in:

AIDS Reviews, 2022, v. 24, n. 1, p. 41, doi. 10.24875/AIDSRev.22000001

By:

Soriano, Vicente;
de-Mendoza, Carmen;
Edagwa, Benson;
Treviño, Ana;
Barreiro, Pablo;
Fernandez-Montero, José V.;
Gendelman, Howard E.

Publication type:

Article