Works by Eckel, Jürgen

Results: 55

A novel insulin analog with unique properties: LysB3,GluB29 insulin induces prominent activation of insulin receptor substrate 2, but marginal phosphorylation of insulin receptor substrate 1.

Published in:

2003

By:

Rakatzi, Irini;
Ramrath, Stefanie;
Ledwig, Daniela;
Dransfeld, Olaf;
Bartels, Thomas;
Seipke, Gerhard;
Eckel, Jürgen;
Eckel, Jürgen

Publication type:

journal article

Impairment of insulin signaling in human skeletal muscle cells by co-culture with human adipocytes.

Published in:

2002

By:

Dietze, Daniela;
Koenen, Marlis;
Röhrig, Karin;
Horikoshi, Hiroyoshi;
Hauner, Hans;
Eckel, Jürgen;
Röhrig, Karin;
Eckel, Jürgen

Publication type:

journal article

Protease-Activated Receptor 2 Promotes Pro-Atherogenic Effects through Transactivation of the VEGF Receptor 2 in Human Vascular Smooth Muscle Cells.

Published in:

Frontiers in Pharmacology, 2017, v. 7, p. 1, doi. 10.3389/fphar.2016.00497

By:

Indrakusuma, Ira;
Romacho, Tania;
Eckel, Jürgen

Publication type:

Article

Eicosapentaenoic acid and arachidonic acid differentially regulate adipogenesis, acquisition of a brite phenotype and mitochondrial function in primary human adipocytes.

Published in:

Molecular Nutrition & Food Research, 2016, v. 60, n. 9, p. 2065, doi. 10.1002/mnfr.201500892

By:

Fleckenstein‐Elsen, Manuela;
Dinnies, Daniela;
Jelenik, Tomas;
Roden, Michael;
Romacho, Tania;
Eckel, Jürgen

Publication type:

Article

Adipose dipeptidyl peptidase-4 and obesity: correlation with insulin resistance and depot-specific release from adipose tissue in vivo and in vitro.

Published in:

2013

By:

Sell, Henrike;
Blüher, Matthias;
Klöting, Nora;
Schlich, Raphaela;
Willems, Miriam;
Ruppe, Florian;
Knoefel, Wolfram Trudo;
Dietrich, Arne;
Fielding, Barbara A;
Arner, Peter;
Frayn, Keith N;
Eckel, Jürgen

Publication type:

journal article

Insulin Glulisine: A Viewpoint by JÃ¼rgen Eckel.

Published in:

Drugs, 2006, v. 66, n. 6, p. 870

By:

Eckel, Jürgen

Publication type:

Article

Oleic acid and adipokines synergize in inducing proliferation and inflammatory signalling in human vascular smooth muscle cells.

Published in:

Journal of Cellular & Molecular Medicine, 2011, v. 15, n. 5, p. 1177, doi. 10.1111/j.1582-4934.2010.01099.x

By:

Lamers, Daniela;
Schlich, Raphaela;
Greulich, Sabrina;
Sasson, Shlomo;
Sell, Henrike;
Eckel, Jürgen

Publication type:

Article

Effect of EDTA on insulin binding and insulin action in isolated cardiocytes from adult rat. Evidence for a functional role of low-affinity insulin receptors.

Published in:

1984

By:

Eckel, Jürgen;
Reinauer, Hans;
Eckel, J;
Reinauer, H

Publication type:

journal article

VEGF in the Crosstalk between Human Adipocytes and Smooth Muscle Cells: Depot-Specific Release from Visceral and Perivascular Adipose Tissue.

Published in:

Mediators of Inflammation, 2013, v. 2013, p. 1, doi. 10.1155/2013/982458

By:

Schlich, Raphaela;
Willems, Miriam;
Greulich, Sabrina;
Ruppe, Florian;
Trudo Knoefel, Wolfram;
Ouwens, D. Margriet;
Maxhera, Bujar;
Lichtenberg, Artur;
Eckel, Jürgen;
Sell, Henrike

Publication type:

Article

Adipo-Myokines: Two Sides of the Same Coin--Mediators of Inflammation and Mediators of Exercise.

Published in:

Mediators of Inflammation, 2013, v. 2013, p. 1, doi. 10.1155/2013/320724

By:

Raschke, Silja;
Eckel, Jürgen

Publication type:

Article

Myokines in metabolic homeostasis and diabetes.

Published in:

Diabetologia, 2019, v. 62, n. 9, p. 1523, doi. 10.1007/s00125-019-4927-9

By:

Eckel, Jürgen

Publication type:

Article

Myokines in insulin resistance and type 2 diabetes.

Published in:

Diabetologia, 2014, v. 57, n. 6, p. 1087, doi. 10.1007/s00125-014-3224-x

By:

Eckardt, Kristin;
Görgens, Sven;
Raschke, Silja;
Eckel, Jürgen

Publication type:

Article

Nutritional Ingredients Modulate Adipokine Secretion and Inflammation in Human Primary Adipocytes.

Published in:

2015

By:

Romacho, Tania;
Glosse, Philipp;
Richter, Isabel;
Elsen, Manuela;
Schoemaker, Marieke H.;
van Tol, Eric A.;
Eckel, Jürgen

Publication type:

Journal Article

1067-P: Development of Novel Modulators of the GABAA Receptor for Diabetes Therapy.

Published in:

Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1067-P

By:

HASSE, BIRGIT;
BELGARDT, BENGT-FREDERIK;
HECHT, MARION;
WÖRDENWEBER, ROBIN;
PIECHOT, ALEXANDER;
RODEN, MICHAEL;
ECKEL, JÜRGEN

Publication type:

Article

Hypoxia in Combination With Muscle Contraction Improves Insulin Action and Glucose Metabolism in Human Skeletal Muscle via the HIF-1α Pathway.

Published in:

2017

By:

Görgens, Sven W.;
Benninghoff, Tim;
Eckardt, Kristin;
Springer, Christian;
Chadt, Alexandra;
Melior, Anita;
Wefers, Jakob;
Cramer, Andrea;
Jensen, Jørgen;
Birkeland, Kåre I.;
Drevon, Christian A.;
Al-Hasani, Hadi;
Eckel, Jürgen

Publication type:

journal article

Epicardial Fat from Guinea Pig: A Model to Study the Paracrine Network of Interactions between Epicardial Fat and Myocardium?

Published in:

Cardiovascular Drugs & Therapy, 2008, v. 22, n. 2, p. 107, doi. 10.1007/s10557-008-6085-z

By:

Janine Swifka;
Jürgen Weiß;
Klaus Addicks;
Jürgen Eckel;
Peter Rösen

Publication type:

Article

Chitinase-3-like protein 1 protects skeletal muscle from TNFa-induced inflammation and insulin resistance.

Published in:

Biochemical Journal, 2014, v. 459, n. 3, p. 479, doi. 10.1042/BJ20131151

By:

GÖRGENS, Sven W.;
ECKARDT, Kristin;
ELSEN, Manuela;
TENNAGELS, Norbert;
ECKEL, Jürgen

Publication type:

Article

Heat Shock Protein 60 in Obesity: Effect of Bariatric Surgery and its Relation to Inflammation and Cardiovascular Risk.

Published in:

2017

By:

Sell, Henrike;
Poitou, Christine;
Habich, Christiane;
Bouillot, Jean‐Luc;
Eckel, Jürgen;
Clément, Karine

Publication type:

journal article

Protein Array Reveals Differentially Expressed Proteins in Subcutaneous Adipose Tissue in Obesity.

Published in:

Obesity (19307381), 2007, v. 15, n. 10, p. 2396

By:

Škopková, Martina;
Penesová, Adela;
Sell, Henrike;
Rádiková, Žofia;
Vlček, Miroslav;
Imrich, Richard;
Koška, Juraj;
Ukropec, Jozef;
Eckel, Jürgen;
Klimeš, Iwar;
Gašperíková, Daniela

Publication type:

Article

Identification of novel putative adipomyokines by a cross-species annotation of secretomes and expression profiles.

Published in:

Archives of Physiology & Biochemistry, 2015, v. 121, n. 5, p. 194, doi. 10.3109/13813455.2015.1092044

By:

Schering, Lisa;
Hoene, Miriam;
Kanzleiter, Timo;
Jähnert, Markus;
Wimmers, Klaus;
Klaus, Susanne;
Eckel, Jürgen;
Weigert, Cora;
Schürmann, Annette;
Maak, Steffen;
Jonas, Wenke;
Sell, Henrike

Publication type:

Article

Adipokines enhance oleic acid-induced proliferation of vascular smooth muscle cells by inducing CD36 expression.

Published in:

Archives of Physiology & Biochemistry, 2015, v. 121, n. 3, p. 81, doi. 10.3109/13813455.2015.1045520

By:

Schlich, Raphaela;
Lamers, Daniela;
Eckel, Jürgen;
Sell, Henrike

Publication type:

Article

Deletion of CD73 promotes dyslipidemia and intramyocellular lipid accumulation in muscle of mice.

Published in:

Archives of Physiology & Biochemistry, 2013, v. 119, n. 2, p. 39, doi. 10.3109/13813455.2012.755547

By:

Burghoff, Sandra;
Flögel, Ulrich;
Bongardt, Sabine;
Burkart, Volker;
Sell, Henrike;
Tucci, Sara;
Ikels, Kathrin;
Eberhard, Daniel;
Kern, Matthias;
Klöting, Nora;
Eckel, Jürgen;
Schrader, Jürgen

Publication type:

Article

Regulation of follistatin-like protein 1 expression and secretion in primary human skeletal muscle cells.

Published in:

Archives of Physiology & Biochemistry, 2013, v. 119, n. 2, p. 75, doi. 10.3109/13813455.2013.768270

By:

Görgens, Sven W.;
Raschke, Silja;
Holven, Kirsten Bjørklund;
Jensen, Jørgen;
Eckardt, Kristin;
Eckel, Jürgen

Publication type:

Article

Secreted proteins from adipose tissue and skeletal muscle -- adipokines, myokines and adipose/muscle cross-talk.

Published in:

Archives of Physiology & Biochemistry, 2011, v. 117, n. 2, p. 47, doi. 10.3109/13813455.2010.535835

By:

Trayhurn, Paul;
Drevon, Christian A.;
Eckel, Jürgen

Publication type:

Article

ProteoMiner™ and SELDI-TOF-MS: A robust and highly reproducible combination for biomarker discovery from whole blood serum.

Published in:

Archives of Physiology & Biochemistry, 2010, v. 116, n. 4/5, p. 174, doi. 10.3109/13813455.2010.501082

By:

Fröbel, Julia;
Hartwig, Sonja;
Paßlack, Waltraud;
Eckel, Jürgen;
Haas, Rainer;
Czibere, Akos;
Lehr, Stefan

Publication type:

Article

Targeting phosphoprotein profiling by combination of hydroxyapatite-based phosphoprotein enrichment and SELDI-TOF MS.

Published in:

Archives of Physiology & Biochemistry, 2010, v. 116, n. 4/5, p. 181, doi. 10.3109/13813455.2010.506219

By:

Vormbrock, Ingo;
Kaber, Gernot;
Hartwig, Sonja;
Eckel, Jürgen;
Schrör, Karsten;
Lehr, Stefan

Publication type:

Article

Enhancing mass spectrometry based serum profiling by a combination of free flow electrophoresis and ClinProt™.

Published in:

Archives of Physiology & Biochemistry, 2009, v. 115, n. 5, p. 259, doi. 10.3109/13813450903286554

By:

Hartwig, Sonja;
Kotzka, Jorg;
Müller, Heidi;
Müller-Wieland, Dirk;
Eckel, Jürgen;
Lehr, Stefan

Publication type:

Article

Combinatorial hexapeptide ligand libraries (ProteoMiner™): An innovative fractionation tool for differential quantitative clinical proteomics.

Published in:

Archives of Physiology & Biochemistry, 2009, v. 115, n. 3, p. 155, doi. 10.1080/13813450903154224

By:

Hartwig, Sonja;
Czibere, Akos;
Kotzka, Jorg;
Paßlack, Waltraud;
Haas, Rainer;
Eckel, Jürgen;
Lehr, Stefan

Publication type:

Article

Insulin analogues: Action profiles beyond glycaemic control.

Published in:

Archives of Physiology & Biochemistry, 2008, v. 114, n. 1, p. 45, doi. 10.1080/13813450801983369

By:

Eckardt, Kristin;
Eckel, Jürgen

Publication type:

Article

Advanced knowledge on long-known diseases - Proceedings of the 4th Eli Lilly International Foundation Workshop.

Published in:

Archives of Physiology & Biochemistry, 2007, v. 113, n. 3, p. 97, doi. 10.1080/13813450701602507

By:

Eckel, Jürgen

Publication type:

Article

Pathways leading to muscle insulin resistance – The muscle – fat connection.

Published in:

Archives of Physiology & Biochemistry, 2006, v. 112, n. 2, p. 105, doi. 10.1080/13813450600711540

By:

Sell, Henrike;
Eckel, Jürgen;
Dietze-Schroeder, Daniela

Publication type:

Article

COST Action B17: A successful network of 27 countries on insulin resistance, obesity and diabetes mellitus in the elderly.

Published in:

Archives of Physiology & Biochemistry, 2006, v. 112, n. 2, p. 59, doi. 10.1080/13813450600735945

By:

Csermely, Peter;
Eckel, Jürgen

Publication type:

Article

Differential phosphorylation of IRS-1 and IRS-2 by insulin and IGF-I receptors.

Published in:

Archives of Physiology & Biochemistry, 2006, v. 112, n. 1, p. 37, doi. 10.1080/13813450500500332

By:

Rakatzi, Irini;
Stosik, Magdalene;
Gromke, Tanja;
Siddle, Kenneth;
Eckel, Jürgen

Publication type:

Article

Differentiation of human adipocytes at physiological oxygen levels results in increased adiponectin secretion and isoproterenol-stimulated lipolysis.

Published in:

Adipocyte, 2012, v. 1, n. 3, p. 132, doi. 10.4161/adip.19962

By:

Famulla, Susanne;
Schlich, Raphaela;
Sell, Henrike;
Eckel, Jürgen

Publication type:

Article

Chemotactic cytokines, obesity and type 2 diabetes: in vivo and in vitro evidence for a possible causal correlation?

Published in:

Proceedings of the Nutrition Society, 2009, v. 68, n. 4, p. 378, doi. 10.1017/S0029665109990218

By:

Sell, Henrike;
Eckel, Jürgen

Publication type:

Article

Eicosanoids and the Regulation of Cardiac Glucose Transport.

Published in:

Annals of the New York Academy of Sciences, 2002, v. 967, n. 1, p. 208, doi. 10.1111/j.1749-6632.2002.tb04277.x

By:

DRANSFELD, OLAF;
RAKATZI, IRINI;
SASSON, SHLOMO;
ECKEL, JÜRGEN

Publication type:

Article

Adipokines and inflammatory markers in elderly subjects with high risk of type 2 diabetes and cardiovascular disease.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31144-8

By:

Saukkonen, Tuula;
Mutt, Shivaprakash Jagalur;
Jokelainen, Jari;
Saukkonen, Anna-Maria;
Raza, Ghulam Shere;
Karhu, Toni;
Härkönen, Pirjo;
Eckel, Jürgen;
Herzig, Karl-Heinz;
Rajala, Ulla;
Keinänen-Kiukaanniemi, Sirkka

Publication type:

Article

DPP4 and ACE2 in Diabetes and COVID-19: Therapeutic Targets for Cardiovascular Complications?

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.01161

By:

Valencia, Inés;
Peiró, Concepción;
Lorenzo, Óscar;
Sánchez-Ferrer, Carlos F.;
Eckel, Jürgen;
Romacho, Tania

Publication type:

Article

Shedding of dipeptidyl peptidase 4 is mediated by metalloproteases and up-regulated by hypoxia in human adipocytes and smooth muscle cells.

Published in:

FEBS Letters, 2014, v. 588, n. 21, p. 3870, doi. 10.1016/j.febslet.2014.08.029

By:

Röhrborn, Diana;
Eckel, Jürgen;
Sell, Henrike

Publication type:

Article

Identification and Validation of Novel Contraction-Regulated Myokines Released from Primary Human Skeletal Muscle Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0062008

By:

Raschke, Silja;
Eckardt, Kristin;
Bjørklund Holven, Kirsten;
Jensen, Jørgen;
Eckel, Jürgen

Publication type:

Article

Positive allosteric γ‐aminobutyric acid type A receptor modulation prevents lipotoxicity‐induced injury in hepatocytes in vitro.

Published in:

Diabetes, Obesity & Metabolism, 2022, v. 24, n. 8, p. 1498, doi. 10.1111/dom.14719

By:

Rohbeck, Elisabeth;
Hasse, Birgit;
Koopmans, Guido;
Romero, Alejandra;
Belgardt, Bengt‐Frederik;
Roden, Michael;
Eckel, Jürgen;
Romacho, Tania

Publication type:

Article

LAPSInsulin115: A novel ultra-long-acting basal insulin with a unique action profile.

Published in:

Diabetes, Obesity & Metabolism, 2017, v. 19, n. 12, p. 1722, doi. 10.1111/dom.13006

By:

Wronkowitz, Nina;
Hartmann, Thorsten;
Görgens, Sven Wolfgang;
Dietze‐Schroeder, Daniela;
Indrakusuma, Ira;
Choi, In Young;
Park, Sung Hee;
Lee, Young‐Mi;
Kwon, Se Chang;
Kang, Yeonjoo;
Hompesch, Marcus;
Eckel, Jürgen

Publication type:

Article

Conditioned medium obtained from in vitro differentiated adipocytes and resistin induce insulin resistance in human hepatocytes

Published in:

FEBS Letters, 2007, v. 581, n. 22, p. 4303, doi. 10.1016/j.febslet.2007.07.076

By:

Zhou, Lei;
Sell, Henrike;
Eckardt, Kristin;
Yang, Zaiqing;
Eckel, Jürgen

Publication type:

Article

Hypothalamic expression of neuropeptide-Y in the New Zealand obese mouse.

Published in:

International Journal of Obesity & Related Metabolic Disorders, 1998, v. 22, n. 12, p. 1172, doi. 10.1038/sj.ijo.0800742

By:

Rizk, N M;
Liu, Li Sen;
Eckel, Jürgen

Publication type:

Article

Chemerin correlates with markers for fatty liver in morbidly obese patients and strongly decreases after weight loss induced by bariatric surgery.

Published in:

2010

By:

Sell, Henrike;
Divoux, Adeline;
Poitou, Christine;
Basdevant, Arnaud;
Bouillot, Jean-Luc;
Bedossa, Pierre;
Tordjman, Joan;
Eckel, Jürgen;
Clément, Karine

Publication type:

journal article

NDUFB6 Polymorphism Is Associated With Physical Activity-Mediated Metabolic Changes in Type 2 Diabetes.

Published in:

Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.693683

By:

Pesta, Dominik;
Jelenik, Tomas;
Zaharia, Oana-Patricia;
Bobrov, Pavel;
Görgens, Sven;
Bódis, Kálmán;
Karusheva, Yanislava;
Krako Jakovljevic, Nina;
Lalic, Nebojsa M.;
Markgraf, Daniel F.;
Burkart, Volker;
Müssig, Karsten;
Knebel, Birgit;
Kotzka, Jörg;
Eckel, Jürgen;
Strassburger, Klaus;
Szendroedi, Julia;
Roden, Michael

Publication type:

Article

Comment on Wu and Spiegelman. Irisin ERKs the Fat. Diabetes 2014;63:381-383.

Published in:

2014

By:

Elsen, Manuela;
Raschke, Silja;
Sommerfeld, Mark;
Gassenhuber, Hans;
Eckel, Jürgen

Publication type:

Journal Article

Irisin ERKs the Fat. Diabetes 2014;63:381-383.

Published in:

2014

By:

Elsen, Manuela;
Raschke, Silja;
Sommerfeld, Mark;
Gassenhuber, Hans;
Eckel, Jürgen

Publication type:

Letter to the Editor

Heat Shock Protein 60 as a Mediator of Adipose Tissue Inflammation and Insulin Resistance.

Published in:

Diabetes, 2012, v. 61, n. 3, p. 615, doi. 10.2337/db10-1574

By:

Mäirker, Tina;
Sell, Henrike;
Zillesen, Pia;
Glöde, Anja;
Kriebel, Jennifer;
Ouwens, D. Margriet;
Pattyn, Piet;
Ruige, Johannes;
Famulla, Susanne;
Roden, Michael;
Eckel, Jürgen;
Habich, Christiane

Publication type:

Article

Chemerin Is a Novel Adipocyte-Derived Factor Inducing Insulin Resistance in Primary Human Skeletal Muscle Cells.

Published in:

Diabetes, 2009, v. 58, n. 12, p. 2731, doi. 10.2337/db09-0277

By:

Sell, Henrike;
Laurencikiene, Jurga;
Taube, Annika;
Eckardt, Kristin;
Cramer, Andrea;
Horrighs, Angelika;
Arner, Peter;
Eckel, Jürgen

Publication type:

Article