Works by Eccles, Suzanne A.

Results: 53

Vascular endothelial growth factor family members are differentially regulated by c-erbB signaling in head and neck squamous carcinoma cells.

Published in:

Clinical & Experimental Metastasis, 2000, v. 18, n. 2, p. 155, doi. 10.1023/A:1006764100867

By:

O-charoenrat, Pornchai;
Rhys-Evans, Peter;
Modjtahedi, Helmout;
Eccles, Suzanne

Publication type:

Article

Differential modulation of proliferation, matrix metalloproteinase expression and invasion of human head and neck squamous carcinoma cells by c-erbB ligands.

Published in:

Clinical & Experimental Metastasis, 1999, v. 17, n. 7, p. 631, doi. 10.1023/A:1006751016860

By:

O-charoenrat, Pornchai;
Rhys-Evans, Peter;
Court, William;
Box, Gary;
Eccles, Suzanne

Publication type:

Article

High ASMA<sup>+</sup> Fibroblasts and Low Cytoplasmic HMGB1<sup>+</sup> Breast Cancer Cells Predict Poor Prognosis.

Published in:

2017

By:

Amornsupak, Kamolporn;
Jamjuntra, Pranisa;
Warnnissorn, Malee;
O-Charoenrat, Pornchai;
Sa-nguanraksa, Doonyapat;
Thuwajit, Peti;
Eccles, Suzanne A.;
Thuwajit, Chanitra

Publication type:

journal article

Decreased tumorigenicity of a transplantable rat sarcoma following transfer and expression of an IL-2 cDNA.

Published in:

International Journal of Cancer, 1991, v. 47, n. 2, p. 244, doi. 10.1002/ijc.2910470213

By:

Russell, Stephen J.;
Eccles, Suzanne A.;
Flemming, Claudia L.;
Johnson, Caroline A.;
Collins, Mary K. L.

Publication type:

Article

Breast Tumour Kinase (Brk/PTK6) Contributes to Breast Tumour Xenograft Growth and Modulates Chemotherapeutic Responses In Vitro.

Published in:

Genes, 2022, v. 13, n. 3, p. 402, doi. 10.3390/genes13030402

By:

Burmi, Rajpal S.;
Box, Gary M.;
Wazir, Umar;
Hussain, Haroon A.;
Davies, Julie A.;
Court, William J.;
Eccles, Suzanne A.;
Jiang, Wen G.;
Mokbel, Kefah;
Harvey, Amanda J.

Publication type:

Article

Heparanase: Breaking down barriers in tumors.

Published in:

Nature Medicine, 1999, v. 5, n. 7, p. 735, doi. 10.1038/10455

By:

Eccles, Suzanne A.

Publication type:

Article

Cancer-associated fibroblasts induce high mobility group box 1 and contribute to resistance to doxorubicin in breast cancer cells.

Published in:

BMC Cancer, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2407-14-955

By:

Amornsupuk, Kamolporn;
Insawang, Tonkla;
Thuwajit, Peti;
O.-Charoenrat, Pornchai;
Eccles, Suzanne A.;
Thuwajit, Chanitra

Publication type:

Article

Cancer-associated fibroblasts induce high mobility group box 1 and contribute to resistance to doxorubicin in breast cancer cells.

Published in:

2014

By:

Amornsupak, Kamolporn;
Insawang, Tonkla;
Thuwajit, Peti;
O-Charoenrat, Pornchai;
Eccles, Suzanne A;
Thuwajit, Chanitra

Publication type:

Journal Article

THE SIGNIFICANCE OF MACROPHAGES IN HUMAN AND EXPERIMENTAL TUMORS*.

Published in:

Annals of the New York Academy of Sciences, 1976, v. 276, n. 1, p. 124, doi. 10.1111/j.1749-6632.1976.tb41641.x

By:

Alexander, Peter;
Eccles, Suzanne A.;
Gauci, C. L. L.

Publication type:

Article

Synthesis and Evaluation of a 2,11-Cembranoid-Inspired Library.

Published in:

Chemistry - A European Journal, 2016, v. 22, n. 16, p. 5657, doi. 10.1002/chem.201505093

By:

Welford, Amanda J;
Caldwell, John J.;
Liu, Manjuan;
Richards, Meirion;
Brown, Nathan;
Lomas, Cara;
Tizzard, Graham J.;
Pitak, Mateusz B.;
Coles, Simon J.;
Eccles, Suzanne A.;
Raynaud, Florence I.;
Collins, Ian

Publication type:

Article

ALK2 inhibitors display beneficial effects in preclinical models of ACVR1 mutant diffuse intrinsic pontine glioma.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0420-8

By:

Carvalho, Diana;
Taylor, Kathryn R.;
Olaciregui, Nagore Gene;
Molinari, Valeria;
Clarke, Matthew;
Mackay, Alan;
Ruddle, Ruth;
Henley, Alan;
Valenti, Melanie;
Hayes, Angela;
Brandon, Alexis De Haven;
Eccles, Suzanne A.;
Raynaud, Florence;
Boudhar, Aicha;
Monje, Michelle;
Popov, Sergey;
Moore, Andrew S.;
Mora, Jaume;
Cruz, Ofelia;
Vinci, Mara

Publication type:

Article

Evaluating Imaging Biomarkers of Acquired Resistance to Targeted EGFR Therapy in Xenograft Models of Human Head and Neck Squamous Cell Carcinoma.

Published in:

Frontiers in Oncology, 2018, p. N.PAG, doi. 10.3389/fonc.2018.00271

By:

Baker, Lauren C. J.;
Sikka, Arti;
Price, Jonathan M.;
Boult, Jessica K. R.;
Lepicard, Elise Y.;
Box, Gary;
Jamin, Yann;
Spinks, Terry J.;
Kramer-Marek, Gabriela;
Leach, Martin O.;
Eccles, Suzanne A.;
Box, Carol;
Robinson, Simon P.

Publication type:

Article

The HSP90 Inhibitor NVP-AUY922 Radiosensitizes by Abrogation of Homologous Recombination Resulting in Mitotic Entry with Unresolved DNA Damage.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0035436

By:

Zaidi, Shane;
McLaughlin, Martin;
Bhide, Shreerang A.;
Eccles, Suzanne A.;
Workman, Paul;
Nutting, Christopher M.;
Huddart, Robert A.;
Harrington, Kevin J.

Publication type:

Article

Application of Meso Scale Technology for the Measurement of Phosphoproteins in Human Tumor Xenografts.

Published in:

Assay & Drug Development Technologies, 2007, v. 5, n. 3, p. 391, doi. 10.1089/adt.2006.044

By:

Sharon M. Gowan;
Anthea Hardcastle;
Albert E. Hallsworth;
Melanie R. Valenti;
Lisa-Jane K. Hunter;
Alexis K. de Haven Brandon;
Michelle D. Garrett;
Florence Raynaud;
Paul Workman;
Wynne Aherne;
Suzanne A. Eccles

Publication type:

Article

Preclinical Evaluation of Imaging Biomarkers for Prostate Cancer Bone Metastasis and Response to Cabozantinib.

Published in:

JNCI: Journal of the National Cancer Institute, 2014, v. 106, n. 4, p. 1, doi. 10.1093/jnci/dju033

By:

Graham, Timothy J.;
Box, Gary;
Tunariu, Nina;
Crespo, Mateus;
Spinks, Terry J.;
Miranda, Susana;
Attard, Gerhardt;
de Bono, Johann;
Eccles, Suzanne A.;
Davies, Faith E.;
Robinson, Simon P.

Publication type:

Article

HIF-1α-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion.

Published in:

Cancer Biology & Therapy, 2014, v. 15, n. 10, p. 1350, doi. 10.4161/cbt.29822

By:

Pires, Isabel M.;
Blokland, Nina J. G.;
Broos, Agnieke W. T.;
Poujade, Flore-Anne;
Senra, Joana M.;
Eccles, Suzanne A.;
Span, Paul N.;
Harvey, Amanda J.;
Hammond, Ester M.

Publication type:

Article

Expression of vascular endothelial growth factor family members in head and neck squamous cell carcinoma correlates with lymph node metastasis.

Published in:

2001

By:

O-charoenrat, Pornchai;
Rhys-Evans, Peter;
Eccles, Suzanne A.;
O-charoenrat, P;
Rhys-Evans, P;
Eccles, S A

Publication type:

journal article

Correction to: An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.

Published in:

2018

By:

Banerji, Udai;
Sain, Nivedita;
Sharp, Swee Y.;
Valenti, Melanie;
Asad, Yasmin;
Ruddle, Ruth;
Raynaud, Florence;
Walton, Michael;
Eccles, Suzanne A.;
Judson, Ian;
Jackman, Ann L.;
Workman, Paul

Publication type:

Correction Notice

Correction to: An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.

Published in:

2018

By:

Banerji, Udai;
Sain, Nivedita;
Sharp, Swee Y;
Valenti, Melanie;
Asad, Yasmin;
Ruddle, Ruth;
Raynaud, Florence;
Walton, Michael;
Eccles, Suzanne A;
Judson, Ian;
Jackman, Ann L;
Workman, Paul

Publication type:

corrected article

An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models.

Published in:

Cancer Chemotherapy & Pharmacology, 2008, v. 62, n. 5, p. 769, doi. 10.1007/s00280-007-0662-x

By:

Banerji, Udai;
Sain, Nivedita;
Sharp, Swee Y.;
Valenti, Melanie;
Asad, Yasmin;
Ruddle, Ruth;
Raynaud, Florence;
Walton, Michael;
Eccles, Suzanne A.;
Judson, Ian;
Jackman, Ann L.;
Workman, Paul

Publication type:

Article

Non-invasive in vivo imaging of vessel calibre in orthotopic prostate tumour xenografts.

Published in:

International Journal of Cancer, 2012, v. 130, n. 6, p. 1284, doi. 10.1002/ijc.26112

By:

Walker-Samuel, Simon;
Boult, Jessica K.R.;
McPhail, Lesley D.;
Box, Gary;
Eccles, Suzanne A.;
Robinson, Simon P.

Publication type:

Article

Metabolomic changes of the multi (-AGC-) kinase inhibitor AT13148 in cells, mice and patients are associated with NOS regulation.

Published in:

Metabolomics, 2020, v. 16, n. 4, p. 1, doi. 10.1007/s11306-020-01676-0

By:

Pal, Akos;
Asad, Yasmin;
Ruddle, Ruth;
Henley, Alan T.;
Swales, Karen;
Decordova, Shaun;
Eccles, Suzanne A.;
Collins, Ian;
Garrett, Michelle D.;
De Bono, Johann;
Banerji, Udai;
Raynaud, Florence I.

Publication type:

Article

Small-Molecule Activation of p53 Blocks Hypoxia-Inducible Factor 1α and Vascular Endothelial Growth Factor Expression In Vivo and Leads to Tumor Cell Apoptosis in Normoxia and Hypoxia.

Published in:

Molecular & Cellular Biology, 2009, v. 29, n. 8, p. 2243, doi. 10.1128/MCB.00959-08

By:

Yang, Jun;
Ahmed, Afshan;
Poon, Evon;
Perusinghe, Nina;
Brandon, Alexis de Haven;
Box, Gary;
Valenti, Melanie;
Eccles, Suzanne;
Rouschop, Kasper;
Wouters, Brad;
Ashcroft, Margaret

Publication type:

Article

Erratum to: Kurt Hellmann D.M., D.Phil. Oxon. A happy 90th birthday!

Published in:

2015

By:

Eccles, Suzanne;
Steiner, Rudolf

Publication type:

Erratum

Kurt Hellmann D. M., D. Phil. Oxon 1922-2013.

Published in:

Clinical & Experimental Metastasis, 2013, v. 30, n. 5, p. 553, doi. 10.1007/s10585-013-9586-5

By:

Eccles, Suzanne

Publication type:

Article

Kurt Hellmann D.M., D.Phil. Oxon. A happy 90th birthday!

Published in:

2012

By:

Eccles, Suzanne;
Steiner, Rudolf

Publication type:

Editorial

Lymphatic metastasis in breast cancer: importance and new insights into cellular and molecular mechanisms.

Published in:

Clinical & Experimental Metastasis, 2007, v. 24, n. 8, p. 619, doi. 10.1007/s10585-007-9123-5

By:

Eccles, Suzanne;
Paon, Lenaic;
Sleeman, Jonathan

Publication type:

Article

Bayesian estimation of changes in transverse relaxation rates.

Published in:

Magnetic Resonance in Medicine, 2010, v. 64, n. 3, p. 914, doi. 10.1002/mrm.22478

By:

Walker-Samuel, Simon;
Orton, Matthew;
McPhail, Lesley D.;
Boult, Jessica K. R.;
Box, Gary;
Eccles, Suzanne A.;
Robinson, Simon P.

Publication type:

Article

PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion.

Published in:

Journal of Cell Biology, 2015, v. 211, n. 4, p. 863, doi. 10.1083/jcb.201501072

By:

Dart, Anna E.;
Box, Gary M.;
Court, William;
Gale, Madeline E.;
Brown, John P.;
Pinder, Sarah E.;
Eccles, Suzanne A.;
Wells, Claire M.

Publication type:

Article

Differentiation and neoplasia. Invasion and metastasis; experimental systems.

Published in:

Journal of Pathology, 1983, v. 141, n. 3, p. 333, doi. 10.1002/path.1711410311

By:

Eccles, Suzanne A.

Publication type:

Article

c-erbB2 Protein Overexpression in Breast Cancer as a Target for PET Using Iodine-124-Labeled Monoclonal Antibodies.

Published in:

Journal of Nuclear Medicine, 1992, v. 33, n. 12, p. 2154

By:

Bakir, M. Adel;
Eccles, Suzanne A.;
Babich, John W.;
Aftab, Nighat;
Styles, Jennifer M.;
Dean, Christopher J.;
Ott, Robert J.

Publication type:

Article

Investigating intracranial tumour growth patterns with multiparametric MRI incorporating Gd-DTPA and USPIO-enhanced imaging.

Published in:

NMR in Biomedicine, 2016, v. 29, n. 11, p. 1608, doi. 10.1002/nbm.3594

By:

Boult, Jessica K.R.;
Borri, Marco;
Jury, Alexa;
Popov, Sergey;
Box, Gary;
Perryman, Lara;
Eccles, Suzanne A.;
Jones, Chris;
Robinson, Simon P.

Publication type:

Article

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.

Published in:

Breast Cancer Research, 2013, v. 15, n. 5, p. 1, doi. 10.1186/bcr3493

By:

Eccles, Suzanne A.;
Aboagye, Eric O.;
Simak Ali;
Anderson, Annie S.;
Armes, Jo;
Berditchevski, Fedor;
Blaydes, Jeremy P.;
Brennan, Keith;
Brown, Nicola J.;
Bryant, Helen E.;
Bundred, Nigel J.;
Burchell, Joy M.;
Campbell, Anna M.;
Carroll, Jason S.;
Clarke, Robert B.;
Coles, Charlotte E.;
Cook, Gary J. R.;
Cox, Angela;
Curtin, Nicola J.;
Dekker, Lodewijk V.

Publication type:

Article

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.

Published in:

2013

By:

Eccles, Suzanne A;
Aboagye, Eric O;
Ali, Simak;
Anderson, Annie S;
Armes, Jo;
Berditchevski, Fedor;
Blaydes, Jeremy P;
Brennan, Keith;
Brown, Nicola J;
Bryant, Helen E;
Bundred, Nigel J;
Burchell, Joy M;
Campbell, Anna M;
Carroll, Jason S;
Clarke, Robert B;
Coles, Charlotte E;
Cook, Gary J R;
Cox, Angela;
Curtin, Nicola J;
Dekker, Lodewijk V

Publication type:

journal article

Molecular pharmacology of phosphatidylinositol 3-kinase inhibition in human glioma.

Published in:

Cell Cycle, 2009, v. 8, n. 3, p. 443, doi. 10.4161/cc.8.3.7643

By:

Guillard, Sandrine;
Clarke, Paul A.;
Poele, Robert te;
Mohri, Zahra;
Bjerke, Lynn;
Valenti, Melanie;
Raynaud, Florence;
Eccles, Suzanne A.;
Workman, Paul

Publication type:

Article

Metabolic biomarkers of response to the AKT inhibitor MK-2206 in pre-clinical models of human colorectal and prostate carcinoma.

Published in:

British Journal of Cancer, 2018, v. 119, n. 9, p. 1118, doi. 10.1038/s41416-018-0242-3

By:

Al-Saffar, Nada M. S.;
Troy, Helen;
Wong Te Fong, Anne-Christine;
Paravati, Roberta;
Jackson, L. Elizabeth;
Gowan, Sharon;
Boult, Jessica K. R.;
Robinson, Simon P.;
Eccles, Suzanne A.;
Yap, Timothy A.;
Leach, Martin O.;
Chung, Yuen-Li

Publication type:

Article

Metabolic biomarkers of response to the AKT inhibitor MK-2206 in pre-clinical models of human colorectal and prostate carcinoma.

Published in:

2018

By:

Al-Saffar, Nada M S;
Troy, Helen;
Wong Te Fong, Anne-Christine;
Paravati, Roberta;
Jackson, L Elizabeth;
Gowan, Sharon;
Boult, Jessica K R;
Robinson, Simon P;
Eccles, Suzanne A;
Yap, Timothy A;
Leach, Martin O;
Chung, Yuen-Li

Publication type:

journal article

Characterisation of CCT271850, a selective, oral and potent MPS1 inhibitor, used to directly measure in vivo MPS1 inhibition vs therapeutic efficacy.

Published in:

2017

By:

Faisal, Amir;
Mak, Grace W Y;
Gurden, Mark D;
Xavier, Cristina P R;
Anderhub, Simon J;
Innocenti, Paolo;
Westwood, Isaac M;
Naud, Sébastien;
Hayes, Angela;
Box, Gary;
Valenti, Melanie R;
De Haven Brandon, Alexis K;
O'Fee, Lisa;
Schmitt, Jessica;
Woodward, Hannah L;
Burke, Rosemary;
vanMontfort, Rob L M;
Blagg, Julian;
Raynaud, Florence I;
Eccles, Suzanne A

Publication type:

journal article

Brk/PTK6 and Involucrin Expression May Predict Breast Cancer Cell Responses to Vitamin D3.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 13, p. 10757, doi. 10.3390/ijms241310757

By:

Box, Carol;
Pennington, Caroline;
Hare, Stephen;
Porter, Sarah;
Edwards, Dylan;
Eccles, Suzanne;
Crompton, Mark;
Harvey, Amanda

Publication type:

Article

Dual Targeting of ErbB2 and MUC1 in Breast Cancer Using Chimeric Antigen Receptors Engineered to Provide Complementary Signaling.

Published in:

Journal of Clinical Immunology, 2012, v. 32, n. 5, p. 1059, doi. 10.1007/s10875-012-9689-9

By:

Wilkie, Scott;
Schalkwyk, May;
Hobbs, Steve;
Davies, David;
Stegen, Sjoukje;
Pereira, Ana;
Burbridge, Sophie;
Box, Carol;
Eccles, Suzanne;
Maher, John

Publication type:

Article

Epigenetic disruption of cadherin-11 in human cancer metastasis.

Published in:

Journal of Pathology, 2012, v. 228, n. 2, p. 230, doi. 10.1002/path.4011

By:

Carmona, F. Javier;
Villanueva, Alberto;
Vidal, August;
Muñoz, Clara;
Puertas, Sara;
Penin, Rosa M;
Gomà, Montserrat;
Lujambio, Amaia;
Piulats, Josep M;
Mesía, Ricard;
Sánchez-Céspedes, Montse;
Manós, Manel;
Condom, Enric;
Eccles, Suzanne A;
Esteller, Manel

Publication type:

Article

Determinants of response to epidermal growth factor receptor tyrosine kinase inhibition in squamous cell carcinoma of the head and neck.

Published in:

Journal of Pathology, 2009, v. 218, n. 1, p. 122, doi. 10.1002/path.2515

By:

Rogers, Susanne J;
Box, Carol;
Chambers, Philip;
Barbachano, Yolanda;
Nutting, Christopher M;
Rhŷs-Evans, Peter;
Workman, Paul;
Harrington, Kevin J;
Eccles, Suzanne A

Publication type:

Article

HMGB1 mediates invasion and PD-L1 expression through RAGE-PI3K/AKT signaling pathway in MDA-MB-231 breast cancer cells.

Published in:

2022

By:

Amornsupak, Kamolporn;
Thongchot, Suyanee;
Thinyakul, Chanida;
Box, Carol;
Hedayat, Somaieh;
Thuwajit, Peti;
Eccles, Suzanne A.;
Thuwajit, Chanitra

Publication type:

journal article

Flexible Targeting of ErbB Dimers That Drive Tumorigenesis by Using Genetically Engineered T Cells.

Published in:

Molecular Medicine, 2012, v. 18, n. 4, p. 565, doi. 10.2119/molmed.2011.00493

By:

Davies, David M.;
Foster, Julie;
van der Stegen, Sjoukje J. C.;
Parente-Pereira, Ana C.;
Chiapero-Stanke, Laura;
Delinassios, George J.;
Burbridge, Sophie E.;
Kao, Vincent;
Zhe Liu;
Bosshard-Carter, Leticia;
van Schalkwyk, May C. I.;
Box, Carol;
Eccles, Suzanne A.;
Mather, Stephen J.;
Wilkie, Scott;
Maher, John

Publication type:

Article

Immunologically-mediated restraint of latent tumour metastases.

Published in:

Nature, 1975, v. 257, n. 5521, p. 52, doi. 10.1038/257052a0

By:

ECCLES, SUZANNE A.;
ALEXANDER, P.

Publication type:

Article

Macrophage content of tumours in relation to metastatic spread and host immune reaction.

Published in:

Nature, 1974, v. 250, n. 5468, p. 667, doi. 10.1038/250667a0

By:

ECCLES, SUZANNE A.;
ALEXANDER, PETER

Publication type:

Article

Signaling pathways required for matrix metalloproteinase-9 induction by betacellulin in head-and-neck squamous carcinoma cells.

Published in:

International Journal of Cancer, 2004, v. 111, n. 2, p. 174, doi. 10.1002/ijc.20228

By:

O-charoenrat, Pornchai;
Wongkajornsilp, Adisak;
Rhys-Evans, Peter H.;
Eccles, Suzanne A.

Publication type:

Article

Use of plasma MMP-2 and MMP-9 levels as a surrogate for tumour expression in colorectal cancer patients.

Published in:

International Journal of Cancer, 2003, v. 107, n. 4, p. 541, doi. 10.1002/ijc.11436

By:

Tutton, Matthew G.;
George, Mark L.;
Eccles, Suzanne A.;
Burton, Sarah;
Swift, R. Ian;
Abulafi, A. Muti

Publication type:

Article

Targeting of cells expressing wild-type EGFR and type-III mutant EGFR (EGFRvIII) by anti-EGFR MAb ICR62: A two-pronged attack for tumour therapy.

Published in:

International Journal of Cancer, 2003, v. 105, n. 2, p. 273, doi. 10.1002/ijc.11055

By:

Helmout Modjtahedi;
David K. Moscatello;
Gary Box;
Margaret Green;
Christine Shotton;
David J. Lamb;
Lesley J. Reynolds;
Albert J. Wong;
Christopher Dean;
Hilary Thomas;
Suzanne Eccles

Publication type:

Article

A synthetic matrix metalloproteinase inhibitor prevents squamous carcinoma cell proliferation by interfering with epidermal growth factor receptor autocrine loops.

Published in:

International Journal of Cancer, 2002, v. 100, n. 5, p. 527, doi. 10.1002/ijc.10531

By:

O-Charoenrat, Pornchai;
Rhys-Evans, Peter;
Eccles, Suzanne

Publication type:

Article