Works matching AU Easton, Douglas F

Results: 154

Genetic evidence and integration of various data sources for classifying uncertain variants into a single model.

Published in:

Human Mutation, 2008, v. 29, n. 11, p. 1265, doi. 10.1002/humu.20897

By:

Goldgar, David E.;
Easton, Douglas F.;
Byrnes, Graham B.;
Spurdle, Amanda B.;
Iversen, Edwin S.;
Greenblatt, Marc S.

Publication type:

Article

Screening for the BRCA1-ins6kbEx13 mutation: potential for misdiagnosis.

Published in:

Human Mutation, 2007, v. 28, n. 5, p. 525, doi. 10.1002/humu.9493

By:

Ramus, Susan J;
Harrington, Patricia A;
Pye, Carole;
Peock, Susan;
Cook, Margaret R;
Cox, Mark J;
Jacobs, Ian J;
DiCioccio, Richard A;
Whittemore, Alice S;
Piver, M Steven;
Easton, Douglas F.;
Ponder, Bruce AJ;
Pharoah, Paul DP;
Gayther, Simon A

Publication type:

Article

pedigreejs: a web-based graphical pedigree editor.

Published in:

Bioinformatics, 2018, v. 34, n. 6, p. 1069, doi. 10.1093/bioinformatics/btx705

By:

Carver, Tim;
Cunningham, Alex P;
Villiers, Chantal Babb de;
Lee, Andrew;
Hartley, Simon;
Tischkowitz, Marc;
Walter, Fiona M;
Easton, Douglas F;
Antoniou, Antonis C

Publication type:

Article

Contralateral breast cancer risk in patients with breast cancer and a germline-BRCA1/2 pathogenic variant undergoing radiation.

Published in:

JNCI: Journal of the National Cancer Institute, 2023, v. 115, n. 11, p. 1318, doi. 10.1093/jnci/djad116

By:

Barele, Mark van;
Akdeniz, Delal;
Heemskerk-Gerritsen, Bernadette A M;
Genepso;
Andrieu, Nadine;
Noguès, Catherine;
HEBON;
Asperen, Christi J van;
Wevers, Marijke;
Ausems, Margreet G E M;
Bock, Geertruida H de;
Dommering, Charlotte J;
Gómez-García, Encarnacion B;
Leeuwen, Flora E van;
Mooij, Thea M;
EMBRACE;
Easton, Douglas F;
Antoniou, Antonis C;
Evans, D Gareth;
Izatt, Louise

Publication type:

Article

Oral Contraceptive Use in BRCA1 and BRCA2 Mutation Carriers: Absolute Cancer Risks and Benefits.

Published in:

2022

By:

Schrijver, Lieske H;
Mooij, Thea M;
Pijpe, Anouk;
Sonke, Gabe S;
Mourits, Marian J E;
Andrieu, Nadine;
Antoniou, Antonis C;
Easton, Douglas F;
Engel, Christoph;
Goldgar, David;
John, Esther M;
Kast, Karin;
Milne, Roger L;
Olsson, Håkan;
Phillips, Kelly-Anne;
Terry, Mary Beth;
Hopper, John L;
Leeuwen, Flora E van;
Rookus, Matti A;
van Leeuwen, Flora E

Publication type:

journal article

Personalizing Breast Cancer Screening Based on Polygenic Risk and Family History.

Published in:

2021

By:

Broek, Jeroen J van den;
Schechter, Clyde B;
Ravesteyn, Nicolien T van;
Janssens, A Cecile J W;
Wolfson, Michael C;
Trentham-Dietz, Amy;
Simard, Jacques;
Easton, Douglas F;
Mandelblatt, Jeanne S;
Kraft, Peter;
Koning, Harry J de;
van den Broek, Jeroen J;
van Ravesteyn, Nicolien T;
de Koning, Harry J

Publication type:

journal article

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers.

Published in:

2017

By:

Kuchenbaecker, Karoline B.;
McGuffog, Lesley;
Barrowdale, Daniel;
Lee, Andrew;
Soucy, Penny;
Dennis, Joe;
Domchek, Susan M.;
Robson, Mark;
Spurdle, Amanda B.;
Ramus, Susan J.;
Mavaddat, Nasim;
Terry, Mary Beth;
Neuhausen, Susan L.;
Schmutzler, Rita Katharina;
Simard, Jacques;
Pharoah, Paul D. P.;
Offit, Kenneth;
Couch, Fergus J.;
Chenevix-Trench, Georgia;
Easton, Douglas F.

Publication type:

journal article

Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer.

Published in:

2015

By:

Hung, Rayjean J.;
Ulrich, Cornelia M.;
Goode, Ellen L.;
Brhane, Yonathan;
Muir, Kenneth;
Chan, Andrew T.;
Le Marchand, Loic;
Schildkraut, Joellen;
Witte, John S.;
Eeles, Rosalind;
Boffetta, Paolo;
Spitz, Margaret R.;
Poirier, Julia G.;
Rider, David N.;
Fridley, Brooke L.;
Zhihua Chen;
Haiman, Christopher;
Schumacher, Fredrick;
Easton, Douglas F.;
Landi, Maria Teresa

Publication type:

journal article

Evidence of a Causal Association Between Insulinemia and Endometrial Cancer: A Mendelian Randomization Analysis.

Published in:

2015

By:

Nead, Kevin T.;
Sharp, Stephen J.;
Thompson, Deborah J.;
Painter, Jodie N.;
Savage, David B.;
Semple, Robert K.;
Barker, Adam;
Perry, John R. B.;
Attia, John;
Dunning, Alison M.;
Easton, Douglas F.;
Holliday, Elizabeth;
Lotta, Luca A.;
O'Mara, Tracy;
McEvoy, Mark;
Pharoah, Paul D. P.;
Scott, Rodney J.;
Spurdle, Amanda B.;
Langenberg, Claudia;
Wareham, Nicholas J.

Publication type:

journal article

The Contributions of Breast Density and Common Genetic Variation to Breast Cancer Risk.

Published in:

JNCI: Journal of the National Cancer Institute, 2015, v. 107, n. 5, p. 1, doi. 10.1093/jnci/dju397

By:

Vachon, Celine M.;
Pankratz, V. Shane;
Scott, Christopher G.;
Haeberle, Lothar;
Ziv, Elad;
Jensen, Matthew R.;
Brandt, Kathleen R.;
Whaley, Dana H.;
Olson, Janet E.;
Heusinger, Katharina;
Hack, Carolin C.;
Jud, Sebastian M.;
Beckmann, Matthias W.;
Schulz-Wendtland, Ruediger;
Tice, Jeffrey A.;
Norman, Aaron D.;
Cunningham, Julie M.;
Purrington, Kristen S.;
Easton, Douglas F.;
Sellers, Thomas A.

Publication type:

Article

The contributions of breast density and common genetic variation to breast cancer risk.

Published in:

2015

By:

Vachon, Celine M;
Pankratz, V Shane;
Scott, Christopher G;
Haeberle, Lothar;
Ziv, Elad;
Jensen, Matthew R;
Brandt, Kathleen R;
Whaley, Dana H;
Olson, Janet E;
Heusinger, Katharina;
Hack, Carolin C;
Jud, Sebastian M;
Beckmann, Matthias W;
Schulz-Wendtland, Ruediger;
Tice, Jeffrey A;
Norman, Aaron D;
Cunningham, Julie M;
Purrington, Kristen S;
Easton, Douglas F;
Sellers, Thomas A

Publication type:

journal article

Is Schizophrenia a Risk Factor for Breast Cancer?—Evidence From Genetic Data.

Published in:

Schizophrenia Bulletin, 2019, v. 45, n. 6, p. 1251, doi. 10.1093/schbul/sby162

By:

Byrne, Enda M;
Ferreira, Manuel A R;
Xue, Angli;
Lindström, Sara;
Jiang, Xia;
Yang, Jian;
Easton, Douglas F;
Wray, Naomi R;
Chenevix-Trench, Georgia

Publication type:

Article

Serum Estradiol and 20 Site-Specific Cancers in Women: Mendelian Randomization Study.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2022, v. 107, n. 2, p. e467, doi. 10.1210/clinem/dgab713

By:

Larsson, Susanna C.;
Kar, Siddhartha;
Perry, John R. B.;
Carter, Paul;
Vithayathil, Mathew;
Mason, Amy M.;
Easton, Douglas F.;
Burgess, Stephen

Publication type:

Article

Exploring the barriers to and facilitators of implementing CanRisk in primary care: a qualitative thematic framework analysis.

Published in:

British Journal of General Practice, 2023, v. 73, n. 733, p. e586, doi. 10.3399/bjgp.2022.0643

By:

Archer, Stephanie;
Donoso, Francisca Stutzin;
Carver, Tim;
Yue, Adelaide;
Cunningham, Alex P;
Ficorella, Lorenzo;
Tischkowitz, Marc;
Easton, Douglas F;
Antoniou, Antonis C;
Emery, Jon;
Usher-Smith, Juliet;
Walter, Fiona M

Publication type:

Article

Corrections to: Use of the BOADICEA Web Application in clinical practice: appraisals by clinicians from various countries.

Published in:

Familial Cancer, 2018, v. 17, n. 3, p. 469, doi. 10.1007/s10689-017-0051-5

By:

Brédart, Anne;
Kop, Jean‑Luc;
Antoniou, Antonis C.;
Cunningham, Alex P.;
De Pauw, Antoine;
Tischkowitz, Marc;
Ehrencrona, Hans;
Dolbeault, Sylvie;
Robieux, Léonore;
Rhiem, Kerstin;
Easton, Douglas F.;
Devilee, Peter;
Stoppa‑Lyonnet, Dominique;
Schmutlzer, Rita

Publication type:

Article

Use of the BOADICEA Web Application in clinical practice: appraisals by clinicians from various countries.

Published in:

Familial Cancer, 2018, v. 17, n. 1, p. 31, doi. 10.1007/s10689-017-0014-x

By:

Brédart, Anne;
Kop, Jean-Luc;
Antoniou, Antonis C.;
Cunningham, Alex P.;
De Pauw, Antoine;
Tischkowitz, Marc;
Ehrencrona, Hans;
Dolbeault, Sylvie;
Robieux, Léonore;
Rhiem, Kerstin;
Easton, Douglas F.;
Devilee, Peter;
Stoppa-Lyonnet, Dominique;
Schmutlzer, Rita

Publication type:

Article

Localisation of susceptibility genes for familial testicular germ cell tumour.

Published in:

APMIS, 2003, v. 111, n. 1, p. 128, doi. 10.1034/j.1600-0463.2003.11101171.x

By:

RAPLEY, ELIZABETH A;
CROCKFORD, GILLIAN P;
EASTON, DOUGLAS F;
STRATTON, MICHAEL R;
BISHOP, D. TIMOTHY

Publication type:

Article

Clinical software development for the Web: lessons learned from the BOADICEA project.

Published in:

BMC Medical Informatics & Decision Making, 2012, v. 12, n. 1, p. 30, doi. 10.1186/1472-6947-12-30

By:

Cunningham, Alex P.;
Antoniou, Antonis C.;
Easton, Douglas F.

Publication type:

Article

The admixture maximum likelihood test to test for association between rare variants and disease phenotypes.

Published in:

BMC Bioinformatics, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2105-14-177

By:

Tyrer, Jonathan P.;
Guo, Qi;
Easton, Douglas F.;
Pharoah, Paul D. P.

Publication type:

Article

Using Family History Data to Improve the Power of Association Studies: Application to Cancer in UK Biobank.

Published in:

Genetic Epidemiology, 2025, v. 49, n. 1, p. 1, doi. 10.1002/gepi.22609

By:

Wilcox, Naomi;
Tyrer, Jonathan P.;
Dennis, Joe;
Yang, Xin;
Perry, John R. B.;
Gardner, Eugene J.;
Easton, Douglas F.

Publication type:

Article

Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers.

Published in:

2017

By:

Kuchenbaecker, Karoline B.;
Hopper, John L.;
Barnes, Daniel R.;
Phillips, Kelly-Anne;
Mooij, Thea M.;
Roos-Blom, Marie-José;
Jervis, Sarah;
van Leeuwen, Flora E.;
Milne, Roger L.;
Andrieu, Nadine;
Goldgar, David E.;
Terry, Mary Beth;
Rookus, Matti A.;
Easton, Douglas F.;
Antoniou, Antonis C.;
and the BRCA1 and BRCA2 Cohort Consortium;
McGuffog, Lesley;
Evans, D Gareth;
Barrowdale, Daniel;
Frost, Debra

Publication type:

journal article

Association of Type and Location of BRCA1 and BRCA2 Mutations With Risk of Breast and Ovarian Cancer.

Published in:

JAMA: Journal of the American Medical Association, 2015, v. 313, n. 13, p. 1347, doi. 10.1001/jama.2014.5985

By:

Rebbeck, Timothy R.;
Mitra, Nandita;
Fei Wan;
Sinilnikova, Olga M.;
Healey, Sue;
McGuffog, Lesley;
Mazoyer, Sylvie;
Chenevix-Trench, Georgia;
Easton, Douglas F.;
Antoniou, Antonis C.;
Nathanson, Katherine L.

Publication type:

Article

Evaluating clinician acceptability of the prototype CanRisk tool for predicting risk of breast and ovarian cancer: A multi-methods study.

Published in:

PLoS ONE, 2020, v. 15, n. 3, p. 1, doi. 10.1371/journal.pone.0229999

By:

Archer, Stephanie;
Babb de Villiers, Chantal;
Scheibl, Fiona;
Carver, Tim;
Hartley, Simon;
Lee, Andrew;
Cunningham, Alex P.;
Easton, Douglas F.;
McIntosh, Jennifer G.;
Emery, Jon;
Tischkowitz, Marc;
Antoniou, Antonis C.;
Walter, Fiona M.

Publication type:

Article

Barriers and Facilitators to Delivering Multifactorial Risk Assessment and Communication for Personalized Breast Cancer Screening: A Qualitative Study Exploring Implementation in Canada.

Published in:

Current Oncology, 2025, v. 32, n. 3, p. 155, doi. 10.3390/curroncol32030155

By:

Walker, Meghan J.;
Neely, Anna;
Antoniou, Antonis C.;
Broeders, Mireille J. M.;
Brooks, Jennifer D.;
Carver, Tim;
Chiquette, Jocelyne;
Easton, Douglas F.;
Eisen, Andrea;
Eloy, Laurence;
Evans, D. Gareth R.;
Fienberg, Samantha;
Joly, Yann;
Kim, Raymond H.;
Knoppers, Bartha M.;
Lofters, Aisha K.;
Nabi, Hermann;
Pashayan, Nora;
Stockley, Tracy L.;
Dorval, Michel

Publication type:

Article

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.

Published in:

Nature Genetics, 2014, v. 46, n. 10, p. 1103, doi. 10.1038/ng.3094

By:

Al Olama, Ali Amin;
Easton, Douglas F;
Kolonel, Laurence N;
Le Marchand, Loic;
Tammela, Teuvo L J;
Auvinen, Anssi;
Wahlfors, Tiina;
Schleutker, Johanna;
Visakorpi, Tapio;
Leinonen, Katri A;
Xu, Jianfeng;
Zheng, S Lilly;
Aly, Markus;
Donovan, Jenny;
Travis, Ruth C;
Key, Tim J;
Kote-Jarai, Zsofia;
Siddiq, Afshan;
Canzian, Federico;
Khaw, Kay-Tee

Publication type:

Article

Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14.

Published in:

Nature Genetics, 2013, v. 45, n. 6, p. 686, doi. 10.1038/ng.2635

By:

Ruark, Elise;
Seal, Sheila;
McDonald, Heather;
Zhang, Feng;
Elliot, Anna;
Lau, KingWai;
Perdeaux, Elizabeth;
Rapley, Elizabeth;
Eeles, Rosalind;
Peto, Julian;
Kote-Jarai, Zsofia;
Muir, Kenneth;
Nsengimana, Jeremie;
Shipley, Janet;
Bishop, D Timothy;
Stratton, Michael R;
Easton, Douglas F;
Huddart, Robert A;
Rahman, Nazneen;
Turnbull, Clare

Publication type:

Article

Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer.

Published in:

Nature Genetics, 2010, v. 42, n. 7, p. 604, doi. 10.1038/ng.607

By:

Turnbull, Clare;
Rapley, Elizabeth A;
Seal, Sheila;
Pernet, David;
Renwick, Anthony;
Hughes, Deborah;
Ricketts, Michelle;
Linger, Rachel;
Nsengimana, Jeremie;
Deloukas, Panagiotis;
Collaboration, UK Testicular Cancer;
Huddart, Robert A;
Bishop, D Timothy;
Easton, Douglas F;
Stratton, Michael R;
Rahman, Nazneen

Publication type:

Article

A genome-wide association study of testicular germ cell tumor.

Published in:

Nature Genetics, 2009, v. 41, n. 7, p. 807, doi. 10.1038/ng.394

By:

Rapley, Elizabeth A.;
Turnbull, Clare;
Al Olama, Ali Amin;
Dermitzakis, Emmanouil T.;
Linger, Rachel;
Huddart, Robert A.;
Renwick, Anthony;
Hughes, Deborah;
Hines, Sarah;
Seal, Sheila;
Morrison, Jonathan;
Nsengimana, Jeremie;
Deloukas, Panagiotis;
Rahman, Nazneen;
Bishop, D. Timothy;
Easton, Douglas F;
Stratton, Michael R.

Publication type:

Article

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

Published in:

Nature Genetics, 2009, v. 41, n. 5, p. 585, doi. 10.1038/ng.354

By:

Easton, Douglas F.

Publication type:

Article

CORRESPONDENCE.

Published in:

2008

By:

Eeles, Rosalinda;
Giles, Graham;
Neal, David;
Muir, Kenneth;
Easton, Douglas F.

Publication type:

Letter

PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene.

Published in:

Nature Genetics, 2007, v. 39, n. 2, p. 165, doi. 10.1038/ng1959

By:

Rahman, Nazneen;
Seal, Sheila;
Thompson, Deborah;
Kelly, Patrick;
Renwick, Anthony;
Elliott, Anna;
Reid, Sarah;
Spanova, Katarina;
Barfoot, Rita;
Chagtai, Tasnim;
Jayatilake, Hiran;
McGuffog, Lesley;
Hanks, Sandra;
Evans, D. Gareth;
Eccles, Diana;
Easton, Douglas F.;
Stratton, Michael R.

Publication type:

Article

Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles.

Published in:

Nature Genetics, 2006, v. 38, n. 11, p. 1239, doi. 10.1038/ng1902

By:

Seal, Sheila;
Thompson, Deborah;
Renwick, Anthony;
Elliott, Anna;
Kelly, Patrick;
Barfoot, Rita;
Chagtai, Tasnim;
Jayatilake, Hiran;
Ahmed, Munaza;
Spanova, Katarina;
North, Bernard;
McGuffog, Lesley;
Evans, D. Gareth;
Eccles, Diana;
Easton, Douglas F.;
Stratton, Michael R.;
Rahman, Nazneen

Publication type:

Article

ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles.

Published in:

Nature Genetics, 2006, v. 38, n. 8, p. 873, doi. 10.1038/ng1837

By:

Renwick, Anthony;
Thompson, Deborah;
Seal, Sheila;
Kelly, Patrick;
Chagtai, Tasnim;
Ahmed, Munaza;
North, Bernard;
Jayatilake, Hiran;
Barfoot, Rita;
Spanova, Katarina;
McGuffog, Lesley;
Evans, D. Gareth;
Eccles, Diana;
Easton, Douglas F.;
Stratton, Michael R.;
Rahman, Nazneen

Publication type:

Article

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.

Published in:

Nature Genetics, 2004, v. 36, n. 6, p. 585, doi. 10.1038/ng1362

By:

Ravikumar, Brinda;
Vacher, Coralie;
Berger, Zdenek;
Davies, Janet E.;
Luo, Shouqing;
Oroz, Lourdes G.;
Scaravilli, Francesco;
Easton, Douglas F.;
Duden, Rainer;
O'Kane, Cahir J.;
Rubinsztein, David C.

Publication type:

Article

Polygenic susceptibility to breast cancer and implications for prevention.

Published in:

Nature Genetics, 2002, v. 31, n. 1, p. 33, doi. 10.1038/ng853

By:

Pharoah, Paul D.P.;
Antoniou, Antonis;
Bobrow, Martin;
Zimmern, Ron L.;
Easton, Douglas F.;
Ponder, Bruce A.J.

Publication type:

Article

Low-penetrance susceptibility to breast cancer due to CHEK2<sup>*</sup>1100delC in noncarriers of BRCA1 or BRCA2 mutations.

Published in:

Nature Genetics, 2002, v. 31, n. 1, p. 55

By:

Meijers-Heijboer, Hanne;
van den Ouweland, Ans;
Klijn, Jan;
Wasielewski, Marijke;
de Snoo, Anja;
Oldenburg, Rogier;
Hollestelle, Antoinette;
Houben, Mark;
Crepin, Ellen;
van Veghel-Plandsoen, Monique;
Elstrodt, Fons;
van Duijn, Cornelia;
Bartels, Carina;
Meijers, Carel;
Schutte, Mieke;
McGuffog, Lesley;
Thompson, Deborah;
Easton, Douglas F.;
Sodha, Nayanta

Publication type:

Article

A common variant in BRCA2 is associated with both breast cancer risk and prenatal viability.

Published in:

Nature Genetics, 2000, v. 26, n. 3, p. 362, doi. 10.1038/81691

By:

Healey, Catherine S.;
Dunning, Alison M.;
Dawn Teare, M.;
Chase, Diana;
Parker, Louise;
Burn, John;
Chang-Claude, Jenny;
Mannermaa, Arto;
Kataja, Vesa;
Huntsman, David G.;
Pharoah, Paul D.P.;
Luben, Robert N.;
Easton, Douglas F.;
Ponder, Bruce A.J.

Publication type:

Article

Cancer incidence in relatives of British Fanconi Anaemia patients.

Published in:

BMC Cancer, 2008, v. 8, p. 1, doi. 10.1186/1471-2407-8-257

By:

Tischkowitz, Marc;
Easton, Douglas F.;
Ball, Jan;
Hodgson, Shirley V.;
Mathew, Christopher G.

Publication type:

Article

Common variation in EMSY and risk of breast and ovarian cancer: a case-control study using HapMap tagging SNPs.

Published in:

BMC Cancer, 2005, v. 5, p. 1, doi. 10.1186/1471-2407-5-81

By:

Benusiglio, Patrick R.;
Lesueur, Fabienne;
Luccarini, Craig;
McIntosh, Joan;
Luben, Robert N.;
Smith, Paula;
Dunning, Alison;
Easton, Douglas F.;
Ponder, Bruce A. J.;
Pharoah, Paul D.

Publication type:

Article

Epidemiological and ES cell‐based functional evaluation of BRCA2 variants identified in families with breast cancer.

Published in:

Human Mutation, 2021, v. 42, n. 2, p. 200, doi. 10.1002/humu.24154

By:

Sullivan, Teresa;
Thirthagiri, Eswary;
Chong, Chan‐Eng;
Stauffer, Stacey;
Reid, Susan;
Southon, Eileen;
Hassan, Tiara;
Ravichandran, Aravind;
Wijaya, Eldarina;
Lim, Joanna;
Taib, Nur Aishah Mohd;
Fadzli, Farhana;
Yip, Cheng Har;
Hartman, Mikael;
Li, Jingmei;
Dam, Rob M.;
North, Susan L.;
Das, Ranabir;
Easton, Douglas F.;
Biswas, Kajal

Publication type:

Article

BRCA1 and BRCA2 pathogenic sequence variants in women of African origin or ancestry.

Published in:

Human Mutation, 2019, v. 40, n. 10, p. 1781, doi. 10.1002/humu.23804

By:

Friebel, Tara M.;
Andrulis, Irene L.;
Balmaña, Judith;
Blanco, Amie M.;
Couch, Fergus J.;
Daly, Mary B.;
Domchek, Susan M.;
Easton, Douglas F.;
Foulkes, William D.;
Ganz, Patricia A.;
Garber, Judy;
Glendon, Gord;
Greene, Mark H.;
Hulick, Peter J.;
Isaacs, Claudine;
Jankowitz, Rachel C.;
Karlan, Beth Y.;
Kirk, Judy;
Kwong, Ava;
Lee, Annette

Publication type:

Article

Genome-wide association study identifies novel breast cancer susceptibility loci.

Published in:

Nature, 2007, v. 447, n. 7148, p. 1087, doi. 10.1038/nature05887

By:

Easton, Douglas F.;
Pooley, Karen A.;
Dunning, Alison M.;
Pharoah, Paul D. P.;
Thompson, Deborah;
Ballinger, Dennis G.;
Struewing, Jeffery P.;
Morrison, Jonathan;
Field, Helen;
Luben, Robert;
Wareham, Nicholas;
Ahmed, Shahana;
Healey, Catherine S.;
Bowman, Richard;
Meyer, Kerstin B.;
Haiman, Christopher A.;
Kolonel, Laurence K.;
Henderson, Brian E.;
Le Marchand, Loic;
Brennan, Paul

Publication type:

Article

Characterisation of PALB2 tumours through whole-exome and whole-transcriptomic analyses.

Published in:

NPJ Breast Cancer, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41523-021-00254-4

By:

Ng, Pei Sze;
Pan, Jia Wern;
Ahmad Zabidi, Muhammad Mamduh;
Rajadurai, Pathmanathan;
Yip, Cheng Har;
Reuda, Oscar M.;
Dunning, Alison M.;
Antoniou, Antonis C.;
Easton, Douglas F.;
Caldas, Carlos;
Chin, Suet-Feung;
Teo, Soo Hwang

Publication type:

Article

Association of germline variation with the survival of women with BRCA1/2 pathogenic variants and breast cancer.

Published in:

NPJ Breast Cancer, 2020, v. 6, n. 1, p. N.PAG, doi. 10.1038/s41523-020-00185-6

By:

Muranen, Taru A.;
Khan, Sofia;
Fagerholm, Rainer;
Aittomäki, Kristiina;
Cunningham, Julie M.;
Dennis, Joe;
Leslie, Goska;
McGuffog, Lesley;
Parsons, Michael T.;
Simard, Jacques;
Slager, Susan;
Soucy, Penny;
Easton, Douglas F.;
Tischkowitz, Marc;
Spurdle, Amanda B.;
Schmutzler, Rita K.;
Wappenschmidt, Barbara;
Hahnen, Eric;
Hooning, Maartje J.;
Singer, Christian F.

Publication type:

Article

Statistical Analysis of Pathogenicity of Somatic Mutations in Cancer.

Published in:

Genetics, 2006, v. 173, n. 4, p. 2187, doi. 10.1534/genetics.105.044677

By:

Greenman, Chris;
Wooster, Richard;
Futreal, P. Andrew;
Stratton, Michael R.;
Easton, Douglas F.

Publication type:

Article

Evaluating the role of alcohol consumption in breast and ovarian cancer susceptibility using population‐based cohort studies and two‐sample Mendelian randomization analyses.

Published in:

International Journal of Cancer, 2021, v. 148, n. 6, p. 1338, doi. 10.1002/ijc.33308

By:

Ong, Jue‐Sheng;
Derks, Eske M.;
Eriksson, Mikael;
An, Jiyuan;
Hwang, Liang‐Dar;
Easton, Douglas F.;
Pharoah, Paul P.;
Berchuck, Andrew;
Kelemen, Linda E.;
Matsuo, Keitaro;
Chenevix‐Trench, Georgia;
Hall, Per;
Bojesen, Stig E.;
Webb, Penelope M.;
MacGregor, Stuart

Publication type:

Article

Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort.

Published in:

International Journal of Cancer, 2019, v. 144, n. 5, p. 1195, doi. 10.1002/ijc.31841

By:

Li, Jingmei;
Wen, Wei Xiong;
Eklund, Martin;
Kvist, Anders;
Eriksson, Mikael;
Christensen, Helene Nordahl;
Torstensson, Astrid;
Bajalica‐Lagercrantz, Svetlana;
Dunning, Alison M.;
Decker, Brennan;
Allen, Jamie;
Luccarini, Craig;
Pooley, Karen;
Simard, Jacques;
Dorling, Leila;
Easton, Douglas F.;
Teo, Soo‐Hwang;
Hall, Per;
Borg, Åke;
Grönberg, Henrik

Publication type:

Article

Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers.

Published in:

2012

By:

Maia, Ana-Teresa;
Antoniou, Antonis C;
O'Reilly, Martin;
Samarajiwa, Shamith;
Dunning, Mark;
Kartsonaki, Christiana;
Chin, Suet-Feung;
Curtis, Christina N;
McGuffog, Lesley;
Domchek, Susan M;
Easton, Douglas F;
Peock, Susan;
Frost, Debra;
Evans, D Gareth;
Eeles, Ros;
Izatt, Louise;
Adlard, Julian;
Eccles, Diana;
Sinilnikova, Olga M;
Mazoyer, Sylvie

Publication type:

journal article

Systematic Minigene-Based Splicing Analysis and Tentative Clinical Classification of 52 CHEK2 Splice-Site Variants.

Published in:

Clinical Chemistry, 2024, v. 70, n. 1, p. 319, doi. 10.1093/clinchem/hvad125

By:

Sanoguera-Miralles, Lara;
Valenzuela-Palomo, Alberto;
Bueno-Martínez, Elena;
Esteban-Sánchez, Ada;
Lorca, Víctor;
Llinares-Burguet, Inés;
García-Álvarez, Alicia;
Pérez-Segura, Pedro;
Infante, Mar;
Easton, Douglas F;
Devilee, Peter;
Vreeswijk, Maaike P G;
de la Hoya, Miguel;
Velasco-Sampedro, Eladio A

Publication type:

Article

Where are the prostate cancer genes?A summary of eight genome wide searches(This work was done on behalf of the International Consortium for Prostate Cancer Genetics (ICPCG).).

Published in:

Prostate, 2003, v. 57, n. 4, p. 261, doi. 10.1002/pros.10300

By:

Douglas F. Easton;
Daniel J. Schaid;
Alice S. Whittemore;
William J. Isaacs

Publication type:

Article