Works by Easton, Douglas

Results: 197

Evaluating the performance of the Breast and Ovarian Analysis of Disease Incidence Algorithm model in predicting 10-year breast cancer risks in UK Biobank.

Published in:

JNCI: Journal of the National Cancer Institute, 2025, v. 117, n. 5, p. 948, doi. 10.1093/jnci/djae335

By:

Petitjean, Carmen;
Wilcox, Naomi;
Ficorella, Lorenzo;
Dennis, Joe;
Tyrer, Jonathan;
Lush, Michael;
Simard, Jacques;
Easton, Douglas;
Antoniou, Antonis C;
Yang, Xin

Publication type:

Article

The functional ALDH2 polymorphism is associated with breast cancer risk: A pooled analysis from the Breast Cancer Association Consortium.

Published in:

Molecular Genetics & Genomic Medicine, 2019, v. 7, n. 6, p. N.PAG, doi. 10.1002/mgg3.707

By:

Ugai, Tomotaka;
Milne, Roger L.;
Ito, Hidemi;
Aronson, Kristan J.;
Bolla, Manjeet K.;
Chan, Tsun;
Chan, Ching W.;
Choi, Ji‐Yeob;
Conroy, Don M.;
Dennis, Joe;
Dunning, Alison M.;
Easton, Douglas F.;
Gaborieau, Valerie;
Gonzalez‐Neira, Anna;
Hartman, Mikael;
Healey, Catherine S.;
Iwasaki, Motoki;
John, Esther M.;
Kang, Daehee;
Kim, Sung‐Won

Publication type:

Article

Implementing Multifactorial Risk Assessment with Polygenic Risk Scores for Personalized Breast Cancer Screening in the Population Setting: Challenges and Opportunities.

Published in:

Cancers, 2024, v. 16, n. 11, p. 2116, doi. 10.3390/cancers16112116

By:

Walker, Meghan J.;
Blackmore, Kristina M.;
Chang, Amy;
Lambert-Côté, Laurence;
Turgeon, Annie;
Antoniou, Antonis C.;
Bell, Kathleen A.;
Broeders, Mireille J. M.;
Brooks, Jennifer D.;
Carver, Tim;
Chiquette, Jocelyne;
Després, Philippe;
Easton, Douglas F.;
Eisen, Andrea;
Eloy, Laurence;
Evans, D. Gareth;
Fienberg, Samantha;
Joly, Yann;
Kim, Raymond H.;
Kim, Shana J.

Publication type:

Article

RAD51D Aberrant Splicing in Breast Cancer: Identification of Splicing Regulatory Elements and Minigene-Based Evaluation of 53 DNA Variants.

Published in:

Cancers, 2021, v. 13, n. 11, p. 2845, doi. 10.3390/cancers13112845

By:

Bueno-Martínez, Elena;
Sanoguera-Miralles, Lara;
Valenzuela-Palomo, Alberto;
Lorca, Víctor;
Gómez-Sanz, Alicia;
Carvalho, Sara;
Allen, Jamie;
Infante, Mar;
Pérez-Segura, Pedro;
Lázaro, Conxi;
Easton, Douglas F.;
Devilee, Peter;
Vreeswijk, Maaike P. G.;
de la Hoya, Miguel;
Velasco, Eladio A.

Publication type:

Article

Comprehensive Functional Characterization and Clinical Interpretation of 20 Splice-Site Variants of the RAD51C Gene.

Published in:

Cancers, 2020, v. 12, n. 12, p. 3771, doi. 10.3390/cancers12123771

By:

Sanoguera-Miralles, Lara;
Valenzuela-Palomo, Alberto;
Bueno-Martínez, Elena;
Llovet, Patricia;
Díez-Gómez, Beatriz;
Caloca, María José;
Pérez-Segura, Pedro;
Fraile-Bethencourt, Eugenia;
Colmena, Marta;
Carvalho, Sara;
Allen, Jamie;
Easton, Douglas F.;
Devilee, Peter;
Vreeswijk, Maaike P. G.;
de la Hoya, Miguel;
Velasco, Eladio A.

Publication type:

Article

Candidate Causal Variants at the 8p12 Breast Cancer Risk Locus Regulate DUSP4.

Published in:

Cancers, 2020, v. 12, n. 1, p. 170, doi. 10.3390/cancers12010170

By:

Glubb, Dylan M.;
Shi, Wei;
Beesley, Jonathan;
Fachal, Laura;
Pritchard, Jayne-Louise;
McCue, Karen;
Barnes, Daniel R.;
Antoniou, Antonis C.;
Dunning, Alison M.;
Easton, Douglas F.;
Chenevix-Trench, Georgia

Publication type:

Article

Genetic susceptibility to breast cancer

Published in:

Molecular Oncology, 2010, v. 4, n. 3, p. 174, doi. 10.1016/j.molonc.2010.04.011

By:

Mavaddat, Nasim;
Antoniou, Antonis C.;
Easton, Douglas F.;
Garcia-Closas, Montserrat

Publication type:

Article

Minigene‐based splicing analysis and ACMG/AMP‐based tentative classification of 56 ATM variants.

Published in:

Journal of Pathology, 2022, v. 258, n. 1, p. 83, doi. 10.1002/path.5979

By:

Bueno‐Martínez, Elena;
Sanoguera‐Miralles, Lara;
Valenzuela‐Palomo, Alberto;
Esteban‐Sánchez, Ada;
Lorca, Víctor;
Llinares‐Burguet, Inés;
Allen, Jamie;
García‐Álvarez, Alicia;
Pérez‐Segura, Pedro;
Durán, Mercedes;
Easton, Douglas F;
Devilee, Peter;
Vreeswijk, Maaike PG;
de la Hoya, Miguel;
Velasco‐Sampedro, Eladio A

Publication type:

Article

Splicing predictions, minigene analyses, and ACMG‐AMP clinical classification of 42 germline PALB2 splice‐site variants.

Published in:

Journal of Pathology, 2022, v. 256, n. 3, p. 321, doi. 10.1002/path.5839

By:

Valenzuela‐Palomo, Alberto;
Bueno‐Martínez, Elena;
Sanoguera‐Miralles, Lara;
Lorca, Víctor;
Fraile‐Bethencourt, Eugenia;
Esteban‐Sánchez, Ada;
Gómez‐Barrero, Susana;
Carvalho, Sara;
Allen, Jamie;
García‐Álvarez, Alicia;
Pérez‐Segura, Pedro;
Dorling, Leila;
Easton, Douglas F;
Devilee, Peter;
Vreeswijk, Maaike PG;
de la Hoya, Miguel;
Velasco, Eladio A

Publication type:

Article

Validation of the BOADICEA model for epithelial tubo-ovarian cancer risk prediction in UK Biobank.

Published in:

British Journal of Cancer, 2024, v. 131, n. 9, p. 1473, doi. 10.1038/s41416-024-02851-z

By:

Yang, Xin;
Wu, Yujia;
Ficorella, Lorenzo;
Wilcox, Naomi;
Dennis, Joe;
Tyrer, Jonathan;
Carver, Tim;
Pashayan, Nora;
Tischkowitz, Marc;
Pharoah, Paul D. P.;
Easton, Douglas F.;
Antoniou, Antonis C.

Publication type:

Article

Proactive breast cancer risk assessment in primary care: a review based on the principles of screening.

Published in:

British Journal of Cancer, 2023, v. 128, n. 9, p. 1636, doi. 10.1038/s41416-023-02145-w

By:

Usher-Smith, Juliet A.;
Hindmarch, Sarah;
French, David P.;
Tischkowitz, Marc;
Moorthie, Sowmiya;
Walter, Fiona M.;
Dennison, Rebecca A.;
Stutzin Donoso, Francisca;
Archer, Stephanie;
Taylor, Lily;
Emery, Jon;
Morris, Stephen;
Easton, Douglas F.;
Antoniou, Antonis C.

Publication type:

Article

BRCA Challenge: BRCA Exchange as a global resource for variants in BRCA1 and BRCA2.

Published in:

PLoS Genetics, 2018, v. 14, n. 12, p. 1, doi. 10.1371/journal.pgen.1007752

By:

Cline, Melissa S.;
Liao, Rachel G.;
Parsons, Michael T.;
Paten, Benedict;
Alquaddoomi, Faisal;
Antoniou, Antonis;
Baxter, Samantha;
Brody, Larry;
Cook-Deegan, Robert;
Coffin, Amy;
Couch, Fergus J.;
Craft, Brian;
Currie, Robert;
Dlott, Chloe C.;
Dolman, Lena;
den Dunnen, Johan T.;
Dyke, Stephanie O. M.;
Domchek, Susan M.;
Easton, Douglas;
Fischmann, Zachary

Publication type:

Article

The cost-utility of magnetic resonance imaging for breast cancer in BRCA1 mutation carriers aged 30-49.

Published in:

2007

By:

Norman, Richard P. A.;
Evans, D. Gareth;
Easton, Douglas F.;
Young, Kenneth C.

Publication type:

journal article

Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses.

Published in:

2016

By:

Khankari, Nikhil K.;
Shu, Xiao-Ou;
Wen, Wanqing;
Kraft, Peter;
Lindström, Sara;
Peters, Ulrike;
Schildkraut, Joellen;
Schumacher, Fredrick;
Bofetta, Paolo;
Risch, Angela;
Bickeböller, Heike;
Amos, Christopher I.;
Easton, Douglas;
Eeles, Rosalind A.;
Gruber, Stephen B.;
Haiman, Christopher A.;
Hunter, David J.;
Chanock, Stephen J.;
Pierce, Brandon L.;
Zheng, Wei

Publication type:

journal article

Epidemiological and ES cell‐based functional evaluation of BRCA2 variants identified in families with breast cancer.

Published in:

Human Mutation, 2021, v. 42, n. 2, p. 200, doi. 10.1002/humu.24154

By:

Sullivan, Teresa;
Thirthagiri, Eswary;
Chong, Chan‐Eng;
Stauffer, Stacey;
Reid, Susan;
Southon, Eileen;
Hassan, Tiara;
Ravichandran, Aravind;
Wijaya, Eldarina;
Lim, Joanna;
Taib, Nur Aishah Mohd;
Fadzli, Farhana;
Yip, Cheng Har;
Hartman, Mikael;
Li, Jingmei;
Dam, Rob M.;
North, Susan L.;
Das, Ranabir;
Easton, Douglas F.;
Biswas, Kajal

Publication type:

Article

Life Stress, Emotional Health, and Mean Telomere Length in the European Prospective Investigation into Cancer (EPIC)-Norfolk Population Study.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2011, v. 66A, n. 11, p. 1152, doi. 10.1093/gerona/glr112

By:

Surtees, Paul G.;
Wainwright, Nicholas W. J.;
Pooley, Karen A.;
Luben, Robert N.;
Khaw, Kay-Tee;
Easton, Douglas F.;
Dunning, Alison M.

Publication type:

Article

Localisation of susceptibility genes for familial testicular germ cell tumour.

Published in:

APMIS, 2003, v. 111, n. 1, p. 128, doi. 10.1034/j.1600-0463.2003.11101171.x

By:

RAPLEY, ELIZABETH A;
CROCKFORD, GILLIAN P;
EASTON, DOUGLAS F;
STRATTON, MICHAEL R;
BISHOP, D. TIMOTHY

Publication type:

Article

Should Age-Dependent Absolute Risk Thresholds Be Used for Risk Stratification in Risk-Stratified Breast Cancer Screening?

Published in:

Journal of Personalized Medicine, 2021, v. 11, n. 9, p. 916, doi. 10.3390/jpm11090916

By:

Pashayan, Nora;
Antoniou, Antonis C.;
Lee, Andrew;
Wolfson, Michael;
Chiquette, Jocelyne;
Eloy, Laurence;
Eisen, Andrea;
Stockley, Tracy L.;
Nabi, Hermann;
Brooks, Jennifer D.;
Dorval, Michel;
Easton, Douglas F.;
Knoppers, Bartha Maria;
Chiarelli, Anna M.;
Simard, Jacques

Publication type:

Article

Personalized Risk Assessment for Prevention and Early Detection of Breast Cancer: Integration and Implementation (PERSPECTIVE I&I).

Published in:

Journal of Personalized Medicine, 2021, v. 11, n. 6, p. 511, doi. 10.3390/jpm11060511

By:

Brooks, Jennifer D.;
Nabi, Hermann H.;
Andrulis, Irene L.;
Antoniou, Antonis C.;
Chiquette, Jocelyne;
Després, Philippe;
Devilee, Peter;
Dorval, Michel;
Droit, Arnaud;
Easton, Douglas F.;
Eisen, Andrea;
Eloy, Laurence;
Fienberg, Samantha;
Goldgar, David;
Hahnen, Eric;
Joly, Yann;
Knoppers, Bartha Maria;
Lofters, Aisha;
Masson, Jean-Yves;
Mittmann, Nicole

Publication type:

Article

Association of single-nucleotide polymorphisms in the cell cycle genes with breast cancer in the British population.

Published in:

Carcinogenesis, 2008, v. 29, n. 2, p. 333, doi. 10.1093/carcin/bgm284

By:

Kristy E. Driver;
Honglin Song;
Fabienne Lesueur;
Shahana Ahmed;
Nuno L. Barbosa-Morais;
Jonathan P. Tyrer;
Bruce A.J. Ponder;
Douglas F. Easton;
Paul D.P. Pharoah;
Alison M. Dunning;
for the Studies in Epidemiology and Risks of Cancer Heredity (SEARCH) Team

Publication type:

Article

Common variants in mismatch repair genes and risk of invasive ovarian cancer.

Published in:

Carcinogenesis, 2006, v. 27, n. 11, p. 2235, doi. 10.1093/carcin/bgl089

By:

Honglin Song;
Susan J. Ramus;
Lydia Quaye;
Richard A. DiCioccio;
Jonathan Tyrer;
Emma Lomas;
Danielle Shadforth;
Estrid Hogdall;
Claus Hogdall;
Valerie McGuire;
Alice S. Whittemore;
Douglas F. Easton;
Bruce A.J. Ponder;
Susanne Kruger Kjaer;
Paul D.P. Pharoah;
Simon A. Gayther

Publication type:

Article

Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility.

Published in:

Nature Communications, 2017, v. 8, n. 12, p. 1, doi. 10.1038/s41467-017-00320-1

By:

Sud, Amit;
Thomsen, Hauke;
Law, Philip J.;
Försti, Asta;
da Silva Filho, Miguel Inacio;
Holroyd, Amy;
Broderick, Peter;
Orlando, Giulia;
Lenive, Oleg;
Wright, Lauren;
Cooke, Rosie;
Easton, Douglas;
Pharoah, Paul;
Dunning, Alison;
Peto, Julian;
Canzian, Federico;
Eeles, Rosalind;
Kote-Jarai, ZSofia;
Muir, Kenneth;
Pashayan, Nora

Publication type:

Article

Is Schizophrenia a Risk Factor for Breast Cancer?—Evidence From Genetic Data.

Published in:

Schizophrenia Bulletin, 2019, v. 45, n. 6, p. 1251, doi. 10.1093/schbul/sby162

By:

Byrne, Enda M;
Ferreira, Manuel A R;
Xue, Angli;
Lindström, Sara;
Jiang, Xia;
Yang, Jian;
Easton, Douglas F;
Wray, Naomi R;
Chenevix-Trench, Georgia

Publication type:

Article

Polyunsaturated fatty acids and prostate cancer risk: a Mendelian randomisation analysis from the PRACTICAL consortium.

Published in:

2016

By:

Khankari, Nikhil K;
Murff, Harvey J;
Zeng, Chenjie;
Wen, Wanqing;
Eeles, Rosalind A;
Easton, Douglas F;
Kote-Jarai, Zsofia;
Al Olama, Ali Amin;
Benlloch, Sara;
Muir, Kenneth;
Giles, Graham G;
Wiklund, Fredrik;
Gronberg, Henrik;
Haiman, Christopher A;
Schleutker, Johanna;
Nordestgaard, Børge G;
Travis, Ruth C;
Donovan, Jenny L;
Pashayan, Nora;
Khaw, Kay-Tee

Publication type:

journal article

No evidence for an association between Saitohin Q7R polymorphism and Alzheimer's disease.

Published in:

Annals of Neurology, 2002, v. 52, n. 5, p. 690, doi. 10.1002/ana.10362

By:

Cook, Lynnette;
Brayne, Carol E.;
Easton, Douglas;
Evans, John Grimley;
Xuereb, John;
Cairns, Nigel J.;
Rubinsztein, David C.

Publication type:

Article

Heat shock proteins HSP70 and GP96: structural insights.

Published in:

Cancer Immunology, Immunotherapy, 2006, v. 55, n. 3, p. 339, doi. 10.1007/s00262-005-0020-y

By:

Facciponte, John G.;
Xiang-Yang Wang;
MacDonald, Ian J.;
Jun-eui Park;
Arnouk, Hilal;
Grimm, Melissa J.;
Ying Li;
Hyung Kim;
Manjili, Masoud H.;
Easton, Douglas P.;
Subjeck, John R.

Publication type:

Article

Rare germline copy number deletions of likely functional importance are implicated in endometrial cancer predisposition.

Published in:

Human Genetics, 2015, v. 134, n. 3, p. 269, doi. 10.1007/s00439-014-1507-4

By:

Moir-Meyer, Gemma;
Pearson, John;
Lose, Felicity;
Scott, Rodney;
McEvoy, Mark;
Attia, John;
Holliday, Elizabeth;
Pharoah, Paul;
Dunning, Alison;
Thompson, Deborah;
Easton, Douglas;
Spurdle, Amanda;
Walker, Logan

Publication type:

Article

Association analysis of 9,560 prostate cancer cases from the International Consortium of Prostate Cancer Genetics confirms the role of reported prostate cancer associated SNPs for familial disease.

Published in:

Human Genetics, 2014, v. 133, n. 3, p. 347, doi. 10.1007/s00439-013-1384-2

By:

Teerlink, Craig;
Thibodeau, Stephen;
McDonnell, Shannon;
Schaid, Daniel;
Rinckleb, Antje;
Maier, Christiane;
Vogel, Walther;
Cancel-Tassin, Geraldine;
Egrot, Christophe;
Cussenot, Olivier;
Foulkes, William;
Giles, Graham;
Hopper, John;
Severi, Gianluca;
Eeles, Ros;
Easton, Douglas;
Kote-Jarai, Zsofia;
Guy, Michelle;
Cooney, Kathleen;
Ray, Anna

Publication type:

Article

Genome-wide association study of endometrial cancer in E2C2.

Published in:

Human Genetics, 2014, v. 133, n. 2, p. 211, doi. 10.1007/s00439-013-1369-1

By:

Vivo, Immaculata;
Prescott, Jennifer;
Setiawan, Veronica;
Olson, Sara;
Wentzensen, Nicolas;
Attia, John;
Black, Amanda;
Brinton, Louise;
Chen, Chu;
Chen, Constance;
Cook, Linda;
Crous-Bou, Marta;
Doherty, Jennifer;
Dunning, Alison;
Easton, Douglas;
Friedenreich, Christine;
Garcia-Closas, Montserrat;
Gaudet, Mia;
Haiman, Christopher;
Hankinson, Susan

Publication type:

Article

Average age-specific cumulative risk of breast cancer according to type and site of germline mutations in BRCA1 and BRCA2 estimated from multiple-case breast cancer families attending Australian family cancer clinics.

Published in:

Human Genetics, 2003, v. 112, n. 5/6, p. 542, doi. 10.1007/s00439-003-0908-6

By:

Scott, Clare L.;
Jenkins, Mark A.;
Southey, Melissa C.;
Davis, Tracey A.;
Leary, Jennifer A.;
Easton, Douglas F.;
Phillips, Kelly-Anne;
Hopper, John L.

Publication type:

Article

Characterisation of PALB2 tumours through whole-exome and whole-transcriptomic analyses.

Published in:

NPJ Breast Cancer, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41523-021-00254-4

By:

Ng, Pei Sze;
Pan, Jia Wern;
Ahmad Zabidi, Muhammad Mamduh;
Rajadurai, Pathmanathan;
Yip, Cheng Har;
Reuda, Oscar M.;
Dunning, Alison M.;
Antoniou, Antonis C.;
Easton, Douglas F.;
Caldas, Carlos;
Chin, Suet-Feung;
Teo, Soo Hwang

Publication type:

Article

Association of germline variation with the survival of women with BRCA1/2 pathogenic variants and breast cancer.

Published in:

NPJ Breast Cancer, 2020, v. 6, n. 1, p. N.PAG, doi. 10.1038/s41523-020-00185-6

By:

Muranen, Taru A.;
Khan, Sofia;
Fagerholm, Rainer;
Aittomäki, Kristiina;
Cunningham, Julie M.;
Dennis, Joe;
Leslie, Goska;
McGuffog, Lesley;
Parsons, Michael T.;
Simard, Jacques;
Slager, Susan;
Soucy, Penny;
Easton, Douglas F.;
Tischkowitz, Marc;
Spurdle, Amanda B.;
Schmutzler, Rita K.;
Wappenschmidt, Barbara;
Hahnen, Eric;
Hooning, Maartje J.;
Singer, Christian F.

Publication type:

Article

Absence of evidence for a familial breast cancer susceptibility gene at chromosome 8p12-p22.

Published in:

Oncogene, 2000, v. 19, n. 36, p. 4170, doi. 10.1038/sj.onc.1203735

By:

Rahman, Nazneen;
Teare, M Dawn;
Seal, Sheila;
Renard, Helene;
Mangion, Jon;
Cour, Chantal;
Thompson, Deborah;
Shugart, Yin;
Eccles, Diana;
Devilee, Peter;
Meijers, Hanne;
Nathanson, Katherine L;
Neuhausen, Susan L;
Weber, Barbara;
Chang-Claude, Jenny;
Easton, Douglas F;
Goldgar, David;
Stratton, Michael R

Publication type:

Article

Polygenic risk scores for prediction of breast cancer in Korean women.

Published in:

International Journal of Epidemiology, 2023, v. 52, n. 3, p. 796, doi. 10.1093/ije/dyac206

By:

Jee, Yon Ho;
Ho, Weang-Kee;
Park, Sohee;
Easton, Douglas F;
Teo, Soo-Hwang;
Jung, Keum Ji;
Kraft, Peter

Publication type:

Article

Use of deep whole-genome sequencing data to identify structure risk variants in breast cancer susceptibility genes.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 5, p. 853, doi. 10.1093/hmg/ddy005

By:

Xingyi Guo;
Jiajun Shi;
Qiuyin Cai;
Xiao-Ou Shu;
Jing He;
Wanqing Wen;
Allen, Jamie;
Pharoah, Paul;
Dunning, Alison;
Hunter, David J.;
Kraft, Peter;
Easton, Douglas F.;
Wei Zheng;
Jirong Long

Publication type:

Article

Polymorphisms in DNA repair genes and epithelial ovarian cancer risk.

Published in:

International Journal of Cancer, 2005, v. 117, n. 4, p. 611, doi. 10.1002/ijc.21047

By:

Auranen, Annika;
Song, Honglin;
Waterfall, Christy;
DiCioccio, Richard A.;
Kuschel, Bettina;
Kjaer, Susanne K.;
Hogdall, Estrid;
Hogdall, Claus;
Stratton, John;
Whittemore, Alice S.;
Easton, Douglas F.;
Ponder, Bruce A.J.;
Novik, Karen L.;
Dunning, Alison M.;
Gayther, Simon;
Pharoah, Paul D.P.

Publication type:

Article

CHEK2 variant I157T may be associated with increased breast cancer risk.

Published in:

International Journal of Cancer, 2004, v. 111, n. 4, p. 543, doi. 10.1002/ijc.20299

By:

Kilpivaara, Outi;
Vahteristo, Pia;
Falck, Jacob;
Syrjäkoski, Kirsi;
Eerola, Hannaleena;
Easton, Douglas;
Bartkova, Jirina;
Lukas, Jiri;
Heikkilä, Päivi;
Aittomäki, Kristiina;
Holli, Kaija;
Blomqvist, Carl;
Kallioniemi, Olli-Pekka;
Bartek, Jiri;
Nevanlinna, Heli

Publication type:

Article

Polyglutamine repeat length in the AIB1 gene modifies breast cancer susceptibility in BRCA1 carriers.

Published in:

International Journal of Cancer, 2004, v. 108, n. 3, p. 399, doi. 10.1002/ijc.11531

By:

Luna Kadouri;
Zsofia Kote-Jarai;
Douglas F. Easton;
Ayala Hubert;
Rifat Hamoudi;
Benjamin Glaser;
Dvorah Abeliovich;
Tamar Peretz

Publication type:

Article

BRCA2 arg372hispolymorphism and epithelial ovarian cancer risk.

Published in:

International Journal of Cancer, 2003, v. 103, n. 3, p. 427, doi. 10.1002/ijc.10814

By:

Auranen, Annika;
Spurdle, Amanda B.;
Chen, Xiaoqing;
Lipscombe, Julian;
Purdie, David M.;
Hopper, John L.;
Green, Adele;
Healey, Catherine S.;
Redman, Karen;
Dunning, Alison M.;
Pharoah, Paul D.;
Easton, Douglas F.;
Ponder, Bruce A.J.;
Chenevix-Trench, Georgia;
Novik, Karen L.

Publication type:

Article

Familial cancer risks to offspring from mothers with 2 primary breast cancers: Leads to cancer syndromes.

Published in:

International Journal of Cancer, 2000, v. 88, n. 1, p. 87, doi. 10.1002/1097-0215(20001001)88:1<87::AID-IJC14>3.0.CO;2-F

By:

Hemminki, Kari;
Vaittinen, Pauli;
Easton, Douglas

Publication type:

Article

Ovarian and breast cancer risks to women in families with two or more cases of ovarian cancer.

Published in:

International Journal of Cancer, 2000, v. 87, n. 1, p. 110, doi. 10.1002/1097-0215(20000701)87:1<110::AID-IJC16>3.0.CO;2-6

By:

Sutcliffe, Siobhan;
Pharoah, Paul D.P.;
Easton, Douglas F.;
Ponder, Bruce A.J.

Publication type:

Article

Barriers and Facilitators to Delivering Multifactorial Risk Assessment and Communication for Personalized Breast Cancer Screening: A Qualitative Study Exploring Implementation in Canada.

Published in:

Current Oncology, 2025, v. 32, n. 3, p. 155, doi. 10.3390/curroncol32030155

By:

Walker, Meghan J.;
Neely, Anna;
Antoniou, Antonis C.;
Broeders, Mireille J. M.;
Brooks, Jennifer D.;
Carver, Tim;
Chiquette, Jocelyne;
Easton, Douglas F.;
Eisen, Andrea;
Eloy, Laurence;
Evans, D. Gareth R.;
Fienberg, Samantha;
Joly, Yann;
Kim, Raymond H.;
Knoppers, Bartha M.;
Lofters, Aisha K.;
Nabi, Hermann;
Pashayan, Nora;
Stockley, Tracy L.;
Dorval, Michel

Publication type:

Article

CORRESPONDENCE.

Published in:

2008

By:

Eeles, Rosalinda;
Giles, Graham;
Neal, David;
Muir, Kenneth;
Easton, Douglas F.

Publication type:

Letter

PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene.

Published in:

Nature Genetics, 2007, v. 39, n. 2, p. 165, doi. 10.1038/ng1959

By:

Rahman, Nazneen;
Seal, Sheila;
Thompson, Deborah;
Kelly, Patrick;
Renwick, Anthony;
Elliott, Anna;
Reid, Sarah;
Spanova, Katarina;
Barfoot, Rita;
Chagtai, Tasnim;
Jayatilake, Hiran;
McGuffog, Lesley;
Hanks, Sandra;
Evans, D. Gareth;
Eccles, Diana;
Easton, Douglas F.;
Stratton, Michael R.

Publication type:

Article

Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles.

Published in:

Nature Genetics, 2006, v. 38, n. 11, p. 1239, doi. 10.1038/ng1902

By:

Seal, Sheila;
Thompson, Deborah;
Renwick, Anthony;
Elliott, Anna;
Kelly, Patrick;
Barfoot, Rita;
Chagtai, Tasnim;
Jayatilake, Hiran;
Ahmed, Munaza;
Spanova, Katarina;
North, Bernard;
McGuffog, Lesley;
Evans, D. Gareth;
Eccles, Diana;
Easton, Douglas F.;
Stratton, Michael R.;
Rahman, Nazneen

Publication type:

Article

ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles.

Published in:

Nature Genetics, 2006, v. 38, n. 8, p. 873, doi. 10.1038/ng1837

By:

Renwick, Anthony;
Thompson, Deborah;
Seal, Sheila;
Kelly, Patrick;
Chagtai, Tasnim;
Ahmed, Munaza;
North, Bernard;
Jayatilake, Hiran;
Barfoot, Rita;
Spanova, Katarina;
McGuffog, Lesley;
Evans, D. Gareth;
Eccles, Diana;
Easton, Douglas F.;
Stratton, Michael R.;
Rahman, Nazneen

Publication type:

Article

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.

Published in:

Nature Genetics, 2004, v. 36, n. 6, p. 585, doi. 10.1038/ng1362

By:

Ravikumar, Brinda;
Vacher, Coralie;
Berger, Zdenek;
Davies, Janet E.;
Luo, Shouqing;
Oroz, Lourdes G.;
Scaravilli, Francesco;
Easton, Douglas F.;
Duden, Rainer;
O'Kane, Cahir J.;
Rubinsztein, David C.

Publication type:

Article

Low-penetrance susceptibility to breast cancer due to CHEK2<sup>*</sup>1100delC in noncarriers of BRCA1 or BRCA2 mutations.

Published in:

Nature Genetics, 2002, v. 31, n. 1, p. 55

By:

Meijers-Heijboer, Hanne;
van den Ouweland, Ans;
Klijn, Jan;
Wasielewski, Marijke;
de Snoo, Anja;
Oldenburg, Rogier;
Hollestelle, Antoinette;
Houben, Mark;
Crepin, Ellen;
van Veghel-Plandsoen, Monique;
Elstrodt, Fons;
van Duijn, Cornelia;
Bartels, Carina;
Meijers, Carel;
Schutte, Mieke;
McGuffog, Lesley;
Thompson, Deborah;
Easton, Douglas F.;
Sodha, Nayanta

Publication type:

Article

Polygenic susceptibility to breast cancer and implications for prevention.

Published in:

Nature Genetics, 2002, v. 31, n. 1, p. 33, doi. 10.1038/ng853

By:

Pharoah, Paul D.P.;
Antoniou, Antonis;
Bobrow, Martin;
Zimmern, Ron L.;
Easton, Douglas F.;
Ponder, Bruce A.J.

Publication type:

Article

A common variant in BRCA2 is associated with both breast cancer risk and prenatal viability.

Published in:

Nature Genetics, 2000, v. 26, n. 3, p. 362, doi. 10.1038/81691

By:

Healey, Catherine S.;
Dunning, Alison M.;
Dawn Teare, M.;
Chase, Diana;
Parker, Louise;
Burn, John;
Chang-Claude, Jenny;
Mannermaa, Arto;
Kataja, Vesa;
Huntsman, David G.;
Pharoah, Paul D.P.;
Luben, Robert N.;
Easton, Douglas F.;
Ponder, Bruce A.J.

Publication type:

Article