Works matching AU ECKHARDT, Matthias

Results: 48

Transgenic overexpression of polysialyltransferase ST8SiaIV under the control of a neuron-specific promoter does not affect brain development but impairs exploratory behavior.

Published in:

Glycobiology, 2019, v. 29, n. 9, p. 657, doi. 10.1093/glycob/cwz040

By:

Fewou, Simon Ngamli;
Röckle, Iris;
Hildebrandt, Herbert;
Eckhardt, Matthias

Publication type:

Article

Polysialyltransferase overexpression in Schwann cells mediates different effects during peripheral nerve regeneration.

Published in:

Glycobiology, 2012, v. 22, n. 1, p. 107, doi. 10.1093/glycob/cwr113

By:

Jungnickel, Julia;
Eckhardt, Matthias;
Haastert-Talini, Kirsten;
Claus, Peter;
Bronzlik, Paul;
Lipokatic-Takacs, Esther;
Maier, Helena;
Gieselmann, Volkmar;
Grothe, Claudia

Publication type:

Article

Sulfatide binding properties of murine and human antiganglioside antibodies.

Published in:

Glycobiology, 2007, v. 17, n. 11, p. 1156, doi. 10.1093/glycob/cwm095

By:

Kate Townson;
Kay N Greenshields;
Jean Veitch;
Dawn Nicholl;
Matthias Eckhardt;
Oxana Galanina;
Nicolai Bovin;
Eric Samain;
Tatiana Antoine;
David Bundle;
Ping Zhang;
Chang Chun Ling;
Hugh J Willison

Publication type:

Article

Functional expression of the CMP-sialic acid transporter in Escherichia coli and its identification as a simple mobile carrier.

Published in:

Glycobiology, 2006, v. 16, n. 1, p. 73

By:

Joe Tiralongo;
Angel Ashikov;
Françoise Routier;
Matthias Eckhardt;
Hans Bakker;
Rita Gerardy-Schahn;
Mark von Itzstein

Publication type:

Article

Genomic organization of the murine polysialyltransferase gene ST8SiaIV (PST‐1).

Published in:

Glycobiology, 1998, v. 8, n. 12, p. 1165, doi. 10.1093/glycob/8.12.1165

By:

Eckhardt, Matthias;
Gerardy‐Schahn, Rita

Publication type:

Article

N-Acetylaspartate Synthase Deficiency Corrects the Myelin Phenotype in a Canavan Disease Mouse Model But Does Not Affect Survival Time.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 43, p. 14501, doi. 10.1523/JNEUROSCI.1056-15.2015

By:

Maier, Helena;
Wang-Eckhardt, Lihua;
Hartmann, Dieter;
Gieselmann, Volkmar;
Eckhardt, Matthias

Publication type:

Article

Differential expression of (dihydro)ceramide synthases in mouse brain: oligodendrocyte-specific expression of CerS2/Lass2.

Published in:

Histochemistry & Cell Biology, 2008, v. 129, n. 2, p. 233, doi. 10.1007/s00418-007-0344-0

By:

Becker, Ivonne;
Wang-Eckhardt, Lihua;
Yaghootfam, Afshin;
Gieselmann, Volkmar;
Eckhardt, Matthias

Publication type:

Article

BDNF and NGF signals originating from sensory ganglia promote cranial motor axon growth.

Published in:

Experimental Brain Research, 2020, v. 238, n. 1, p. 111, doi. 10.1007/s00221-019-05694-w

By:

Li, Lianlian;
Pu, Qin;
Hintze, Maik;
Wang, Yong;
Eckhardt, Matthias;
Gieselmann, Volkmar;
Tiemann, Inga;
Qi, Xufeng;
Cai, Dongqing;
Wang, Jianlin;
Huang, Ruijin

Publication type:

Article

The PGRMC1 Antagonist AG-205 Inhibits Synthesis of Galactosylceramide and Sulfatide.

Published in:

Cells (2073-4409), 2021, v. 10, n. 12, p. 3520, doi. 10.3390/cells10123520

By:

Wang-Eckhardt, Lihua;
Becker, Ivonne;
Eckhardt, Matthias

Publication type:

Article

Molecular cloning and functional expression of bacteriophage PK1E--encoded endoneuraminidase Endo NE.

Published in:

Molecular Microbiology, 1995, v. 16, n. 3, p. 441, doi. 10.1111/j.1365-2958.1995.tb02409.x

By:

Gerardy-Schahn, Rita;
Bethe, Andrea;
Brennecke, Thomas;
Mühlenhoff, Martina;
Eckhardt, Matthias;
Ziesing, Stefan;
Lottspeich, Friedrich;
Frosch, Matthias

Publication type:

Article

Increasing Sulfatide Synthesis in Myelin-Forming Cells of Arylsulfatase A-Deficient Mice Causes Demyelination and Neurological Symptoms Reminiscent of Human Metachromatic Leukodystrophy.

Published in:

Journal of Neuroscience, 2007, v. 27, n. 35, p. 9482, doi. 10.1523/JNEUROSCI.2287-07.2007

By:

Ramakrishnan, Hariharasubramanian;
Khalaj Hedayati, Kerstin;
Lüllmann-Rauch, Renate;
Wessig, Carsten;
Ngamli Fewou, Simon;
Maier, Helena;
Goebel, Hans-Hilmar;
Gieselmann, Volkmar;
Eckhardt, Matthias

Publication type:

Article

Sulfatide Storage in Neurons Causes Hyperexcitability and Axonal Degeneration in a Mouse Model of Metachromatic Leukodystrophy.

Published in:

Journal of Neuroscience, 2007, v. 27, n. 34, p. 9009, doi. 10.1523/JNEUROSCI.2329-07.2007

By:

Eckhardt, Matthias;
Hedayati, Kerstin Khalaj;
Pitsch, Julika;
Lüllmann-Rauch, Renate;
Beck, Heinz;
Fewou, Simon Ngamli;
Gieselmann, Volkmar

Publication type:

Article

The gene defective in leukocyte adhesion deficiency II encodes a putative GDP-fucose transporter.

Published in:

Nature Genetics, 2001, v. 28, n. 1, p. 69, doi. 10.1038/ng0501-69

By:

Lühn, Kerstin;
Wild, Martin K.;
Eckhardt, Matthias;
Gerardy-Schahn, Rita;
Vestweber, Dietmar

Publication type:

Article

A progesterone receptor membrane component 1 antagonist induces large vesicles independent of progesterone receptor membrane component 1 expression.

Published in:

Biological Chemistry, 2020, v. 401, n. 9, p. 1093, doi. 10.1515/hsz-2019-0417

By:

Wang-Eckhardt, Lihua;
Eckhardt, Matthias

Publication type:

Article

Absence of endogenous carnosine synthesis does not increase protein carbonylation and advanced lipoxidation end products in brain, kidney or muscle.

Published in:

Amino Acids, 2022, v. 54, n. 7, p. 1013, doi. 10.1007/s00726-022-03150-8

By:

Wang-Eckhardt, Lihua;
Becker, Ivonne;
Wang, Yong;
Yuan, Jing;
Eckhardt, Matthias

Publication type:

Article

Decreased turnover of the CNS myelin protein Opalin in a mouse model of hereditary spastic paraplegia 35.

Published in:

Human Molecular Genetics, 2020, v. 29, n. 22, p. 3616, doi. 10.1093/hmg/ddaa246

By:

Hardt, Robert;
Jordans, Silvia;
Winter, Dominic;
Gieselmann, Volkmar;
Wang-Eckhardt, Lihua;
Eckhardt, Matthias

Publication type:

Article

A commercial human protamine-2 antibody used in several studies to detect mouse protamine-2 recognizes mouse transition protein-2 but not protamine-2.

Published in:

Molecular Human Reproduction, 2015, v. 21, n. 11, p. 825, doi. 10.1093/molehr/gav046

By:

Eckhardt, Matthias;
Wang-Eckhardt, Lihua

Publication type:

Article

Fatty Acid 2-Hydroxylase and 2-Hydroxylated Sphingolipids: Metabolism and Function in Health and Diseases.

Published in:

2023

By:

Eckhardt, Matthias

Publication type:

Literature Review

A Highly Convergent Total Synthetic Route to Glycopeptides Carrying a High-Mannose Core Pentasaccharide Domain N-linked to a Natural Peptide Motif.

Published in:

Chemistry - A European Journal, 1997, v. 3, n. 10, p. 1617, doi. 10.1002/chem.19970031011

By:

Danishefsky, Samuel J.;
Hu, Shuanghua;
Cirillo, Pier F.;
Eckhardt, Matthias;
Seeberger, Peter H.

Publication type:

Article

Oligodendrocyte‐specific ceramide galactosyltransferase (CGT) expression phenotypically rescues CGT‐deficient mice and demonstrates that CGT activity does not limit brain galactosylceramide level.

Published in:

Glia (0894-1491), 2005, v. 52, n. 3, p. 190, doi. 10.1002/glia.20230

By:

Inge Zöller;
Heinrich Büssow;
Volkmar Gieselmann;
Matthias Eckhardt

Publication type:

Article

Topography of ncam antigenic epitopes recognized by SCLC-cluster-1 antibodies. A consensus view.

Published in:

International Journal of Cancer, 1994, v. 57, p. 27, doi. 10.1002/ijc.2910570705

By:

Gerardy-Schan, Rita;
Eckhardt, Matthias;
Ledermann, Jonathan;
Kemshead, John T.

Publication type:

Article

SGLT6 - A pharmacological target for the treatment of obesity?

Published in:

Adipocyte, 2018, v. 7, n. 4, p. 277, doi. 10.1080/21623945.2018.1516098

By:

Baader-Pagler, Tamara;
Eckhardt, Matthias;
Himmelsbach, Frank;
Sauer, Achim;
Stierstorfer, Birgit E.;
Hamilton, Bradford S.

Publication type:

Article

Absence of 2-Hydroxylated Sphingolipids Is Compatible with Normal Neural Development But Causes Late-Onset Axon and Myelin Sheath Degeneration.

Published in:

Journal of Neuroscience, 2008, v. 28, n. 39, p. 9741, doi. 10.1523/JNEUROSCI.0458-08.2008

By:

Zöller, Inge;
Meixner, Marion;
Hartmann, Dieter;
Büssow, Heinrich;
Meyer, Rainer;
Gieselmann, Volkmar;
Eckhardt, Matthias

Publication type:

Article

Imaging of complex sulfatides SM3 and SB1a in mouse kidney using MALDI-TOF/TOF mass spectrometry.

Published in:

Analytical & Bioanalytical Chemistry, 2011, v. 401, n. 1, p. 53, doi. 10.1007/s00216-011-4802-0

By:

Marsching, Christian;
Eckhardt, Matthias;
Gröne, Hermann-Josef;
Sandhoff, Roger;
Hopf, Carsten

Publication type:

Article

Unusual 5'-regulatory structure and regulation of the murine Mlc1 gene: Lack of promoter-specific functional elements.

Published in:

Journal of Nucleic Acids Investigation, 2011, v. 2, n. 1-3, p. 70, doi. 10.4081/jnai.2011.2314

By:

Henseler, Darja;
Turner, Jonathan D.;
Eckhardt, Matthias;
Van Der Mark, Maaike;
Revsin, Yanina;
Lin, Michelle K.;
Kranz, Thorsten;
Muller, Claude P.;
Meyer, Jobst

Publication type:

Article

Mice deficient in the NAAG synthetase II gene Rimkla are impaired in a novel object recognition task.

Published in:

Journal of Neurochemistry, 2021, v. 157, n. 6, p. 2008, doi. 10.1111/jnc.15333

By:

Becker, Ivonne;
Wang‐Eckhardt, Lihua;
Lodder‐Gadaczek, Julia;
Wang, Yong;
Grünewald, Agathe;
Eckhardt, Matthias

Publication type:

Article

NAAG synthetase deficiency has only low influence on pathogenesis in a Canavan disease mouse model.

Published in:

Journal of Inherited Metabolic Disease, 2024, v. 47, n. 2, p. 230, doi. 10.1002/jimd.12693

By:

Becker, Ivonne;
Wang‐Eckhardt, Lihua;
Eckhardt, Matthias

Publication type:

Article

Molecular characterization of eukaryotic polysialyltransferase-1.

Published in:

Nature, 1995, v. 373, n. 6516, p. 715, doi. 10.1038/373715a0

By:

Eckhardt, Matthias;
Muhlenhoff, Martina

Publication type:

Article

Arylsulfatase A Overexpressing Human iPSC-derived Neural Cells Reduce CNS Sulfatide Storage in a Mouse Model of Metachromatic Leukodystrophy.

Published in:

Molecular Therapy, 2015, v. 23, n. 9, p. 1519, doi. 10.1038/mt.2015.106

By:

Doerr, Jonas;
Böckenhoff, Annika;
Ewald, Benjamin;
Ladewig, Julia;
Eckhardt, Matthias;
Gieselmann, Volkmar;
Matzner, Ulrich;
Brüstle, Oliver;
Koch, Philipp

Publication type:

Article

Pathology and Current Treatment of Neurodegenerative Sphingolipidoses.

Published in:

NeuroMolecular Medicine, 2010, v. 12, n. 4, p. 362, doi. 10.1007/s12017-010-8133-7

By:

Eckhardt, Matthias

Publication type:

Article

Myelination in the absence of UDP-galactose:ceramide galactosyl-transferase and fatty acid 2 -hydroxylase.

Published in:

2011

By:

Meixner, Marion;
Jungnickel, Julia;
Grothe, Claudia;
Gieselmann, Volkmar;
Eckhardt, Matthias

Publication type:

journal article

Myelination in the absence of UDP-galactose: ceramide galactosyl-transferase and fatty acid 2-hydroxylase.

Published in:

BMC Neuroscience, 2011, v. 12, n. 1, p. 22, doi. 10.1186/1471-2202-12-22

By:

Meixner, Marion;
Jungnickel, Julia;
Grothe, Claudia;
Gieselmann, Volkmar;
Eckhardt, Matthias

Publication type:

Article

CNS myelin protein 36K regulates oligodendrocyte differentiation through Notch.

Published in:

Glia (0894-1491), 2020, v. 68, n. 3, p. 509, doi. 10.1002/glia.23732

By:

Nagarajan, Bhuvaneswari;
Harder, Alexander;
Japp, Anna;
Häberlein, Felix;
Mingardo, Enrico;
Kleinert, Henning;
Yilmaz, Öznur;
Zoons, Angelika;
Rau, Birgit;
Christ, Andrea;
Kubitscheck, Ulrich;
Eiberger, Britta;
Sandhoff, Roger;
Eckhardt, Matthias;
Hartmann, Dieter;
Odermatt, Benjamin

Publication type:

Article

Case Report: Hemophagocytic Lymphohistiocytosis and Non-Tuberculous Mycobacteriosis Caused by a Novel GATA2 Variant.

Published in:

Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.682934

By:

Mika, Thomas;
Vangala, Deepak;
Eckhardt, Matthias;
La Rosée, Paul;
Lange, Christoph;
Lehmberg, Kai;
Wohlschläger, Charlotte;
Biskup, Saskia;
Fuchs, Ilka;
Mann, Jasmin;
Ehl, Stephan;
Warnatz, Klaus;
Schroers, Roland

Publication type:

Article

The First Model of the Neocarzinostatin Chromophore with an Epoxide Ring and a Carbonate Moiety.

Published in:

Angewandte Chemie International Edition, 1996, v. 35, n. 10, p. 1093, doi. 10.1002/anie.199610931

By:

Eckhardt, Matthias;
Brückner, Reinhard

Publication type:

Article

BI 1356, a Novel and Selective Xanthine Based Competitive DPP-IV Inhibitor, Has a Longer Off-Rate from the DPP-IV Enzyme than Vildagliptin.

Published in:

Diabetes, 2007, v. 56, p. A543

By:

Mark, Michael;
Himmelsbach, Frank;
Eckhardt, Matthias;
Langkopf, Elke;
Thomas, Leo

Publication type:

Article

Elevated sulfatide levels in neurons cause lethal audiogenic seizures in mice.

Published in:

Journal of Neurochemistry, 2010, v. 112, n. 1, p. 282, doi. 10.1111/j.1471-4159.2009.06458.x

By:

van Zyl, Rebekka;
Gieselmann, Volkmar;
Eckhardt, Matthias

Publication type:

Article

Reversal of non-hydroxy : α-hydroxy galactosylceramide ratio and unstable myelin in transgenic mice overexpressing UDP-galactose : ceramide galactosyltransferase.

Published in:

Journal of Neurochemistry, 2005, v. 94, n. 2, p. 469, doi. 10.1111/j.1471-4159.2005.03221.x

By:

Fewou, Simon N.;
Büssow, Heinrich;
Schaeren-Wiemers, Nicole;
Vanier, Marie T.;
Macklin, Wendy B.;
Gieselmann, Volkmar;
Eckhardt, Matthias

Publication type:

Article

Citrylglutamate synthase deficient male mice are subfertile with impaired histone and transition protein 2 removal in late spermatids.

Published in:

Biochemical Journal, 2022, v. 479, n. 9, p. 953, doi. 10.1042/BCJ20210844

By:

Wang-Eckhardt, Lihua;
Sylvester, Marc;
Becker, Ivonne;
Allam, Jean-Pierre;
Eckhardt, Matthias

Publication type:

Article

Identification of progesterone receptor membrane component-1 as an interaction partner and possible regulator of fatty acid 2-hydroxylase.

Published in:

Biochemical Journal, 2018, v. 475, n. 5, p. 853, doi. 10.1042/BCJ20170963

By:

Hardt, Robert;
Winter, Dominic;
Gieselmann, Volkmar;
Eckhardt, Matthias

Publication type:

Article

Ceramide synthase 4 deficiency in mice causes lipid alterations in sebum and results in alopecia.

Published in:

Biochemical Journal, 2014, v. 461, n. 1, p. 147, doi. 10.1042/BJ20131242

By:

EBEL, Philipp;
IMGRUND, Silke;
DORP, Katharina VOM;
HOFMANN, Kristina;
MAIER, Helena;
DRAKE, Helena;
DEGEN, Joachim;
DÖRMANN, Peter;
ECKHARDT, Matthias;
FRANZ, Thomas;
WILLECKE, Klaus

Publication type:

Article

Vesicular uptake of N-acetylaspartylglutamate is catalysed by sialin (SLC17A5).

Published in:

Biochemical Journal, 2013, v. 454, n. 1, p. 31, doi. 10.1042/BJ20130300

By:

LODDER-GADACZEK, Julia;
GIESELMANN, Volkmar;
ECKHARDT, Matthias

Publication type:

Article

Optical genome mapping reveals additional prognostic information compared to conventional cytogenetics in AML/MDS patients.

Published in:

International Journal of Cancer, 2022, v. 150, n. 12, p. 1998, doi. 10.1002/ijc.33942

By:

Gerding, Wanda M.;
Tembrink, Marco;
Nilius‐Eliliwi, Verena;
Mika, Thomas;
Dimopoulos, Fotios;
Ladigan‐Badura, Swetlana;
Eckhardt, Matthias;
Pohl, Michael;
Wünnenberg, Max;
Farshi, Pakhshan;
Reimer, Peter;
Schroers, Roland;
Nguyen, Huu Phuc;
Vangala, Deepak B.

Publication type:

Article

Age-Dependent Increase in Schmidt-Lanterman Incisures and a Cadm4-Associated Membrane Skeletal Complex in Fatty Acid 2-hydroxylase Deficient Mice: a Mouse Model of Spastic Paraplegia SPG35.

Published in:

Molecular Neurobiology, 2022, v. 59, n. 7, p. 3969, doi. 10.1007/s12035-022-02832-4

By:

Jordans, Silvia;
Hardt, Robert;
Becker, Ivonne;
Winter, Dominic;
Wang-Eckhardt, Lihua;
Eckhardt, Matthias

Publication type:

Article

The Role and Metabolism of Sulfatide in the Nervous System.

Published in:

Molecular Neurobiology, 2008, v. 37, n. 2/3, p. 93, doi. 10.1007/s12035-008-8022-3

By:

Eckhardt, Matthias

Publication type:

Article

Mutation of FA2H underlies a complicated form of hereditary spastic paraplegia (SPG35).

Published in:

Human Mutation, 2010, v. 31, n. 4, p. E1251, doi. 10.1002/humu.21205

By:

Dick, Katherine J.;
Eckhardt, Matthias;
Paisán-Ruiz, Coro;
Alshehhi, Aisha Alkhayat;
Proukakis, Christos;
Sibtain, Naomi A.;
Maier, Helena;
Sharifi, Reza;
Patton, Michael A.;
Bashir, Wafa;
Koul, Roshan;
Raeburn, Sandy;
Gieselmann, Volkmar;
Houlden, Henry;
Crosby, Andrew H.

Publication type:

Article

Efficacy of enzyme replacement therapy in an aggravated mouse model of metachromatic leukodystrophy declines with age.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 11, p. 2599, doi. 10.1093/hmg/dds086

By:

Matthes, Frank;
Stroobants, Stijn;
Gerlach, Debora;
Wohlenberg, Claudia;
Wessig, Carsten;
Fogh, Jens;
Gieselmann, Volkmar;
Eckhardt, Matthias;
D'Hooge, Rudi;
Matzner, Ulrich

Publication type:

Article

Delay of myelin formation in arylsulphatase A-deficient mice.

Published in:

European Journal of Neuroscience, 2005, v. 21, n. 3, p. 711, doi. 10.1111/j.1460-9568.2005.03891.x

By:

Yaghootfam, Afshin;
Gieselmann, Volkmar;
Eckhardt, Matthias

Publication type:

Article