Works by Durden, Donald

Results: 26

Nilotinib, an approved leukemia drug, inhibits smoothened signaling in Hedgehog-dependent medulloblastoma.
Published in:
PLoS ONE, 2019, v. 14, n. 9, p. 1, doi. 10.1371/journal.pone.0214901
By:
- Chahal, Kirti Kandhwal;
- Li, Jie;
- Kufareva, Irina;
- Parle, Milind;
- Durden, Donald L.;
- Wechsler-Reya, Robert J.;
- Chen, Clark C.;
- Abagyan, Ruben
Publication type:
Article
A triple action CDK4/6-PI3K-BET inhibitor with augmented cancer cell cytotoxicity.
Published in:
2020
By:
- Burgoyne, Adam M.;
- Vann, Kendra R.;
- Joshi, Shweta;
- Morales, Guillermo A.;
- Vega, Francisco M.;
- Singh, Alok;
- Pal, Dhananjaya;
- Merati, Aran B.;
- Kutateladze, Tatiana G.;
- Durden, Donald L.
Publication type:
Letter
PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma.
Published in:
PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0150836
By:
- Singh, Alok R.;
- Joshi, Shweta;
- Zulcic, Muamera;
- Alcaraz, Michael;
- Garlich, Joseph R.;
- Morales, Guillermo A.;
- Cho, Yoon J.;
- Bao, Lei;
- Levy, Michael L.;
- Newbury, Robert;
- Malicki, Denise;
- Messer, Karen;
- Crawford, John;
- Durden, Donald L.
Publication type:
Article
Knockout Serum Replacement Promotes Cell Survival by Preventing BIM from Inducing Mitochondrial Cytochrome C Release.
Published in:
PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0140585
By:
- Ishii, Yuki;
- Nhiayi, May Keu;
- Tse, Edison;
- Cheng, Jonathan;
- Massimino, Michele;
- Durden, Donald L.;
- Vigneri, Paolo;
- Wang, Jean Y. J.
Publication type:
Article
PI3K‐α/mTOR/BRD4 inhibitor alone or in combination with other anti‐virals blocks replication of SARS‐CoV‐2 and its variants of concern including Delta and Omicron.
Published in:
Clinical & Translational Medicine, 2022, v. 12, n. 4, p. 1, doi. 10.1002/ctm2.806
By:
- Acharya, Arpan;
- Pathania, Anup S.;
- Pandey, Kabita;
- Thurman, Michellie;
- Vann, Kendra R.;
- Kutateladze, Tatiana G.;
- Challagundala, Kishore B.;
- Durden, Donald L.;
- Byrareddy, Siddappa N.
Publication type:
Article
Characterization of the effects of asparaginase from escherichia coli and a glutaminase-free asparaginase from vibrio succinogenes on specific cell-mediated cytotoxicity.
Published in:
International Journal of Cancer, 1981, v. 27, n. 1, p. 59, doi. 10.1002/ijc.2910270110
By:
- Durden, Donald L.;
- Distasio, John A.
Publication type:
Article
Mouse mammary tumor virus (MMTV) antigen(s) are present on B lymphocytes of BALB/c mice.
Published in:
International Journal of Cancer, 1979, v. 24, n. 6, p. 813, doi. 10.1002/ijc.2910240620
By:
- Charyulu, Vijaya;
- Sigel, M. Michael;
- Durden, Donald L.;
- Lopez, Diana M.
Publication type:
Article
A PKC-SHP1 signaling axis desensitizes Fcγ receptor signaling by reducing the tyrosine phosphorylation of CBL and regulates FcγR mediated phagocytosis.
Published in:
BMC Immunology, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2172-15-18
By:
- Joshi, Shweta;
- Alok Ranjan Singh;
- Zulcic, Muamera;
- Durden, Donald L.
Publication type:
Article
PTEN status mediates 2ME2 anti-tumor efficacy in preclinical glioblastoma models: role of HIF1α suppression.
Published in:
Journal of Neuro-Oncology, 2014, v. 116, n. 1, p. 89, doi. 10.1007/s11060-013-1283-3
By:
- Muh, Carrie;
- Joshi, Shweta;
- Singh, Alok;
- Kesari, Santosh;
- Durden, Donald;
- Makale, Milan
Publication type:
Article
Vascular remodeling underlies rebleeding in hemophilic arthropathy.
Published in:
American Journal of Hematology, 2015, v. 90, n. 11, p. 1027, doi. 10.1002/ajh.24133
By:
- Bhat, Vikas;
- Olmer, Merissa;
- Joshi, Shweta;
- Durden, Donald L.;
- Cramer, Thomas J.;
- Barnes, Richard FW;
- Ball, Scott T.;
- Hughes, Tudor H.;
- Silva, Mauricio;
- Luck, James V.;
- Moore, Randy E.;
- Mosnier, Laurent O.;
- von Drygalski, Annette
Publication type:
Article
The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity.
Published in:
Scientific Reports, 2017, p. 41643, doi. 10.1038/srep41643
By:
- Nguyen, Hien Anh;
- Durden, Donald L.;
- Lavie, Arnon
Publication type:
Article
Glutaminase-free asparaginase from vibrio succinogenes: An antilymphoma enzyme lacking hepatotoxicity.
Published in:
International Journal of Cancer, 1982, v. 30, n. 3, p. 343, doi. 10.1002/ijc.2910300314
By:
- Distasio, John A.;
- Salazar, Ana M.;
- Nadji, Mehrdad;
- Durden, Donald L.
Publication type:
Article
Rac2 is required for alternative macrophage activation and bleomycin induced pulmonary fibrosis; a macrophage autonomous phenotype.
Published in:
PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0182851
By:
- Joshi, Shweta;
- Singh, Alok R.;
- Wong, Simon S.;
- Zulcic, Muamera;
- Jiang, Min;
- Pardo, Annie;
- Selman, Moises;
- Hagood, James S.;
- Durden, Donald L.
Publication type:
Article
Preclinical activity of a novel multi-axis inhibitor in aggressive and indolent B-cell malignancies.
Published in:
Leukemia & Lymphoma, 2023, v. 64, n. 14, p. 2333, doi. 10.1080/10428194.2023.2256914
By:
- Smith, Audrey L.;
- Pal, Dhananjaya;
- Martinez-Rico, Rolando;
- Eiken, Alexandria P.;
- Durden, Donald L.;
- Kutateladze, Tatiana G.;
- El-Gamal, Dalia
Publication type:
Article
Pan-PI-3 kinase inhibitor SF1126 shows antitumor and antiangiogenic activity in renal cell carcinoma.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 595, doi. 10.1007/s00280-014-2639-x
By:
- Joshi, Shweta;
- Singh, Alok;
- Durden, Donald
Publication type:
Article
An integrin-targeted, pan-isoform, phosphoinositide-3 kinase inhibitor, SF1126, has activity against multiple myeloma in vivo.
Published in:
Cancer Chemotherapy & Pharmacology, 2013, v. 71, n. 4, p. 867, doi. 10.1007/s00280-013-2078-0
By:
- De, Pradip;
- Dey, Nandini;
- Terakedis, Breanne;
- Bergsagel, P.;
- Li, Zhi;
- Mahadevan, Daruka;
- Garlich, Joseph;
- Trudel, Suzanne;
- Makale, Milan;
- Durden, Donald
Publication type:
Article
The PI-3 kinase-Akt-MDM2-survivin signaling axis in high-risk neuroblastoma: a target for PI-3 kinase inhibitor intervention.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 2, p. 325, doi. 10.1007/s00280-010-1486-7
By:
- Peirce, Susan;
- Findley, Harry;
- Prince, Chengyu;
- Dasgupta, Anindya;
- Cooper, Todd;
- Durden, Donald
Publication type:
Article
In vitro evaluation of pan-PI3-kinase inhibitor SF1126 in trastuzumab-sensitive and trastuzumab-resistant HER2-over-expressing breast cancer cells.
Published in:
Cancer Chemotherapy & Pharmacology, 2010, v. 65, n. 4, p. 697, doi. 10.1007/s00280-009-1075-9
By:
- Ozbay, Tuba;
- Durden, Donald L.;
- Tongrui Liu;
- O'Regan, Ruth M.;
- Nahta, Rita
Publication type:
Article
Preclinical Evaluation of a Novel Dual Targeting PI3Kδ/BRD4 Inhibitor, SF2535, in B-Cell Acute Lymphoblastic Leukemia.
Published in:
Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.766888
By:
- Ruan, Yongsheng;
- Kim, Hye Na;
- Ogana, Heather A.;
- Wan, Zesheng;
- Hurwitz, Samantha;
- Nichols, Cydney;
- Abdel-Azim, Nour;
- Coba, Ariana;
- Seo, Seyoung;
- Loh, Yong-Hwee Eddie;
- Gang, Eun Ji;
- Abdel-Azim, Hisham;
- Hsieh, Chih-Lin;
- Lieber, Michael R.;
- Parekh, Chintan;
- Pal, Dhananjay;
- Bhojwani, Deepa;
- Durden, Donald L.;
- Kim, Yong-Mi
Publication type:
Article
Amino Acids Regulate Cisplatin Insensitivity in Neuroblastoma.
Published in:
Cancers, 2020, v. 12, n. 9, p. 2576, doi. 10.3390/cancers12092576
By:
- Gunda, Venugopal;
- Pathania, Anup S.;
- Chava, Srinivas;
- Prathipati, Philip;
- Chaturvedi, Nagendra K.;
- Coulter, Don W.;
- Pandey, Manoj K.;
- Durden, Donald L.;
- Challagundla, Kishore B.
Publication type:
Article
LC–MS/MS method for the quantitation of a dual PI3K/BRD4 inhibitor SF2523 in mouse plasma: Application to plasma protein binding and metabolism studies.
Published in:
Biomedical Chromatography, 2023, v. 37, n. 8, p. 1, doi. 10.1002/bmc.5643
By:
- Bala, Veenu;
- Chhonker, Yashpal S.;
- Morales, Guillermo A.;
- Maddeboina, Krishnaiah;
- Pal, Dhananjaya;
- Durden, Donald L.;
- Murry, Daryl J.
Publication type:
Article
Design of thienopyranone-based BET inhibitors that bind multiple synthetic lethality targets.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-68964-6
By:
- Vann, Kendra R.;
- Pal, Dhananjaya;
- Morales, Guillermo A.;
- Burgoyne, Adam M.;
- Durden, Donald L.;
- Kutateladze, Tatiana G.
Publication type:
Article
COVID-19 and Cancer Comorbidity: Therapeutic Opportunities and Challenges.
Published in:
Theranostics, 2021, v. 11, n. 2, p. 731, doi. 10.7150/thno.51471
By:
- Pathania, Anup S.;
- Prathipati, Philip;
- Abdul, Bakrudeen A. A.;
- Chava, Srinivas;
- Katta, Santharam S.;
- Gupta, Subash C.;
- Gangula, Pandu R.;
- Pandey, Manoj K.;
- Durden, Donald L.;
- Byrareddy, Siddappa N.;
- Challagundla, Kishore B.
Publication type:
Article
Rac2 Controls Tumor Growth, Metastasis and M1-M2 Macrophage Differentiation <i>In Vivo</i>.
Published in:
PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0095893
By:
- Joshi, Shweta;
- Singh, Alok R.;
- Zulcic, Muamera;
- Bao, Lei;
- Messer, Karen;
- Ideker, Trey;
- Dutkowski, Janusz;
- Durden, Donald L.
Publication type:
Article
Heterozygosity for Pten Promotes Tumorigenesis in a Mouse Model of Medulloblastoma.
Published in:
PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010849
By:
- Castellino, Robert C.;
- Barwick, Benjamin G.;
- Schniederjan, Matthew;
- Buss, Meghan C.;
- Becher, Oren;
- Hambardzumyan, Dolores;
- MacDonald, Tobey J.;
- Brat, Daniel J.;
- Durden, Donald L.
Publication type:
Article
CSK Controls Retinoic Acid Receptor (RAR) Signaling: a RAR-c-SRC Signaling Axis Is Required for Neuritogenic Differentiation.
Published in:
Molecular & Cellular Biology, 2007, v. 27, n. 11, p. 26, doi. 10.1128/MCB.01352-06
By:
- Dey, Nandini;
- De, Pradip K.;
- Mu Wang;
- Hongying Zhang;
- Dobrota, Erika A.;
- Robertson, Kent A.;
- Durden, Donald L.
Publication type:
Article