Works by Durden, Donald

Results: 26

PTEN status mediates 2ME2 anti-tumor efficacy in preclinical glioblastoma models: role of HIF1α suppression.

Published in:

Journal of Neuro-Oncology, 2014, v. 116, n. 1, p. 89, doi. 10.1007/s11060-013-1283-3

By:

Muh, Carrie;
Joshi, Shweta;
Singh, Alok;
Kesari, Santosh;
Durden, Donald;
Makale, Milan

Publication type:

Article

Vascular remodeling underlies rebleeding in hemophilic arthropathy.

Published in:

American Journal of Hematology, 2015, v. 90, n. 11, p. 1027, doi. 10.1002/ajh.24133

By:

Bhat, Vikas;
Olmer, Merissa;
Joshi, Shweta;
Durden, Donald L.;
Cramer, Thomas J.;
Barnes, Richard FW;
Ball, Scott T.;
Hughes, Tudor H.;
Silva, Mauricio;
Luck, James V.;
Moore, Randy E.;
Mosnier, Laurent O.;
von Drygalski, Annette

Publication type:

Article

A triple action CDK4/6-PI3K-BET inhibitor with augmented cancer cell cytotoxicity.

Published in:

2020

By:

Burgoyne, Adam M.;
Vann, Kendra R.;
Joshi, Shweta;
Morales, Guillermo A.;
Vega, Francisco M.;
Singh, Alok;
Pal, Dhananjaya;
Merati, Aran B.;
Kutateladze, Tatiana G.;
Durden, Donald L.

Publication type:

Letter

Preclinical Evaluation of a Novel Dual Targeting PI3Kδ/BRD4 Inhibitor, SF2535, in B-Cell Acute Lymphoblastic Leukemia.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.766888

By:

Ruan, Yongsheng;
Kim, Hye Na;
Ogana, Heather A.;
Wan, Zesheng;
Hurwitz, Samantha;
Nichols, Cydney;
Abdel-Azim, Nour;
Coba, Ariana;
Seo, Seyoung;
Loh, Yong-Hwee Eddie;
Gang, Eun Ji;
Abdel-Azim, Hisham;
Hsieh, Chih-Lin;
Lieber, Michael R.;
Parekh, Chintan;
Pal, Dhananjay;
Bhojwani, Deepa;
Durden, Donald L.;
Kim, Yong-Mi

Publication type:

Article

Nilotinib, an approved leukemia drug, inhibits smoothened signaling in Hedgehog-dependent medulloblastoma.

Published in:

PLoS ONE, 2019, v. 14, n. 9, p. 1, doi. 10.1371/journal.pone.0214901

By:

Chahal, Kirti Kandhwal;
Li, Jie;
Kufareva, Irina;
Parle, Milind;
Durden, Donald L.;
Wechsler-Reya, Robert J.;
Chen, Clark C.;
Abagyan, Ruben

Publication type:

Article

Pan-PI-3 kinase inhibitor SF1126 shows antitumor and antiangiogenic activity in renal cell carcinoma.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 3, p. 595, doi. 10.1007/s00280-014-2639-x

By:

Joshi, Shweta;
Singh, Alok;
Durden, Donald

Publication type:

Article

An integrin-targeted, pan-isoform, phosphoinositide-3 kinase inhibitor, SF1126, has activity against multiple myeloma in vivo.

Published in:

Cancer Chemotherapy & Pharmacology, 2013, v. 71, n. 4, p. 867, doi. 10.1007/s00280-013-2078-0

By:

De, Pradip;
Dey, Nandini;
Terakedis, Breanne;
Bergsagel, P.;
Li, Zhi;
Mahadevan, Daruka;
Garlich, Joseph;
Trudel, Suzanne;
Makale, Milan;
Durden, Donald

Publication type:

Article

The PI-3 kinase-Akt-MDM2-survivin signaling axis in high-risk neuroblastoma: a target for PI-3 kinase inhibitor intervention.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 2, p. 325, doi. 10.1007/s00280-010-1486-7

By:

Peirce, Susan;
Findley, Harry;
Prince, Chengyu;
Dasgupta, Anindya;
Cooper, Todd;
Durden, Donald

Publication type:

Article

In vitro evaluation of pan-PI3-kinase inhibitor SF1126 in trastuzumab-sensitive and trastuzumab-resistant HER2-over-expressing breast cancer cells.

Published in:

Cancer Chemotherapy & Pharmacology, 2010, v. 65, n. 4, p. 697, doi. 10.1007/s00280-009-1075-9

By:

Ozbay, Tuba;
Durden, Donald L.;
Tongrui Liu;
O'Regan, Ruth M.;
Nahta, Rita

Publication type:

Article

Preclinical activity of a novel multi-axis inhibitor in aggressive and indolent B-cell malignancies.

Published in:

Leukemia & Lymphoma, 2023, v. 64, n. 14, p. 2333, doi. 10.1080/10428194.2023.2256914

By:

Smith, Audrey L.;
Pal, Dhananjaya;
Martinez-Rico, Rolando;
Eiken, Alexandria P.;
Durden, Donald L.;
Kutateladze, Tatiana G.;
El-Gamal, Dalia

Publication type:

Article

PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma.

Published in:

PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0150836

By:

Singh, Alok R.;
Joshi, Shweta;
Zulcic, Muamera;
Alcaraz, Michael;
Garlich, Joseph R.;
Morales, Guillermo A.;
Cho, Yoon J.;
Bao, Lei;
Levy, Michael L.;
Newbury, Robert;
Malicki, Denise;
Messer, Karen;
Crawford, John;
Durden, Donald L.

Publication type:

Article

Glutaminase-free asparaginase from vibrio succinogenes: An antilymphoma enzyme lacking hepatotoxicity.

Published in:

International Journal of Cancer, 1982, v. 30, n. 3, p. 343, doi. 10.1002/ijc.2910300314

By:

Distasio, John A.;
Salazar, Ana M.;
Nadji, Mehrdad;
Durden, Donald L.

Publication type:

Article

Rac2 is required for alternative macrophage activation and bleomycin induced pulmonary fibrosis; a macrophage autonomous phenotype.

Published in:

PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0182851

By:

Joshi, Shweta;
Singh, Alok R.;
Wong, Simon S.;
Zulcic, Muamera;
Jiang, Min;
Pardo, Annie;
Selman, Moises;
Hagood, James S.;
Durden, Donald L.

Publication type:

Article

Amino Acids Regulate Cisplatin Insensitivity in Neuroblastoma.

Published in:

Cancers, 2020, v. 12, n. 9, p. 2576, doi. 10.3390/cancers12092576

By:

Gunda, Venugopal;
Pathania, Anup S.;
Chava, Srinivas;
Prathipati, Philip;
Chaturvedi, Nagendra K.;
Coulter, Don W.;
Pandey, Manoj K.;
Durden, Donald L.;
Challagundla, Kishore B.

Publication type:

Article

CSK Controls Retinoic Acid Receptor (RAR) Signaling: a RAR-c-SRC Signaling Axis Is Required for Neuritogenic Differentiation.

Published in:

Molecular & Cellular Biology, 2007, v. 27, n. 11, p. 26, doi. 10.1128/MCB.01352-06

By:

Dey, Nandini;
De, Pradip K.;
Mu Wang;
Hongying Zhang;
Dobrota, Erika A.;
Robertson, Kent A.;
Durden, Donald L.

Publication type:

Article

COVID-19 and Cancer Comorbidity: Therapeutic Opportunities and Challenges.

Published in:

Theranostics, 2021, v. 11, n. 2, p. 731, doi. 10.7150/thno.51471

By:

Pathania, Anup S.;
Prathipati, Philip;
Abdul, Bakrudeen A. A.;
Chava, Srinivas;
Katta, Santharam S.;
Gupta, Subash C.;
Gangula, Pandu R.;
Pandey, Manoj K.;
Durden, Donald L.;
Byrareddy, Siddappa N.;
Challagundla, Kishore B.

Publication type:

Article

A PKC-SHP1 signaling axis desensitizes Fcγ receptor signaling by reducing the tyrosine phosphorylation of CBL and regulates FcγR mediated phagocytosis.

Published in:

BMC Immunology, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2172-15-18

By:

Joshi, Shweta;
Alok Ranjan Singh;
Zulcic, Muamera;
Durden, Donald L.

Publication type:

Article

Characterization of the effects of asparaginase from escherichia coli and a glutaminase-free asparaginase from vibrio succinogenes on specific cell-mediated cytotoxicity.

Published in:

International Journal of Cancer, 1981, v. 27, n. 1, p. 59, doi. 10.1002/ijc.2910270110

By:

Durden, Donald L.;
Distasio, John A.

Publication type:

Article

Mouse mammary tumor virus (MMTV) antigen(s) are present on B lymphocytes of BALB/c mice.

Published in:

International Journal of Cancer, 1979, v. 24, n. 6, p. 813, doi. 10.1002/ijc.2910240620

By:

Charyulu, Vijaya;
Sigel, M. Michael;
Durden, Donald L.;
Lopez, Diana M.

Publication type:

Article

Design of thienopyranone-based BET inhibitors that bind multiple synthetic lethality targets.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-68964-6

By:

Vann, Kendra R.;
Pal, Dhananjaya;
Morales, Guillermo A.;
Burgoyne, Adam M.;
Durden, Donald L.;
Kutateladze, Tatiana G.

Publication type:

Article

PI3K‐α/mTOR/BRD4 inhibitor alone or in combination with other anti‐virals blocks replication of SARS‐CoV‐2 and its variants of concern including Delta and Omicron.

Published in:

Clinical & Translational Medicine, 2022, v. 12, n. 4, p. 1, doi. 10.1002/ctm2.806

By:

Acharya, Arpan;
Pathania, Anup S.;
Pandey, Kabita;
Thurman, Michellie;
Vann, Kendra R.;
Kutateladze, Tatiana G.;
Challagundala, Kishore B.;
Durden, Donald L.;
Byrareddy, Siddappa N.

Publication type:

Article

Knockout Serum Replacement Promotes Cell Survival by Preventing BIM from Inducing Mitochondrial Cytochrome C Release.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0140585

By:

Ishii, Yuki;
Nhiayi, May Keu;
Tse, Edison;
Cheng, Jonathan;
Massimino, Michele;
Durden, Donald L.;
Vigneri, Paolo;
Wang, Jean Y. J.

Publication type:

Article

Rac2 Controls Tumor Growth, Metastasis and M1-M2 Macrophage Differentiation <i>In Vivo</i>.

Published in:

PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0095893

By:

Joshi, Shweta;
Singh, Alok R.;
Zulcic, Muamera;
Bao, Lei;
Messer, Karen;
Ideker, Trey;
Dutkowski, Janusz;
Durden, Donald L.

Publication type:

Article

Heterozygosity for Pten Promotes Tumorigenesis in a Mouse Model of Medulloblastoma.

Published in:

PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010849

By:

Castellino, Robert C.;
Barwick, Benjamin G.;
Schniederjan, Matthew;
Buss, Meghan C.;
Becher, Oren;
Hambardzumyan, Dolores;
MacDonald, Tobey J.;
Brat, Daniel J.;
Durden, Donald L.

Publication type:

Article

LC–MS/MS method for the quantitation of a dual PI3K/BRD4 inhibitor SF2523 in mouse plasma: Application to plasma protein binding and metabolism studies.

Published in:

Biomedical Chromatography, 2023, v. 37, n. 8, p. 1, doi. 10.1002/bmc.5643

By:

Bala, Veenu;
Chhonker, Yashpal S.;
Morales, Guillermo A.;
Maddeboina, Krishnaiah;
Pal, Dhananjaya;
Durden, Donald L.;
Murry, Daryl J.

Publication type:

Article

The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity.

Published in:

Scientific Reports, 2017, p. 41643, doi. 10.1038/srep41643

By:

Nguyen, Hien Anh;
Durden, Donald L.;
Lavie, Arnon

Publication type:

Article