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Machine learning‐based clustering identifies obesity subgroups with differential multi‐omics profiles and metabolic patterns.
Published in:
Obesity (19307381), 2024, v. 32, n. 11, p. 2024, doi. 10.1002/oby.24137
By:
- Anwar, Mohammad Y.;
- Highland, Heather;
- Buchanan, Victoria Lynn;
- Graff, Mariaelisa;
- Young, Kristin;
- Taylor, Kent D.;
- Tracy, Russell P.;
- Durda, Peter;
- Liu, Yongmei;
- Johnson, Craig W.;
- Aguet, Francois;
- Ardlie, Kristin G.;
- Gerszten, Robert E.;
- Clish, Clary B.;
- Lange, Leslie A.;
- Ding, Jingzhong;
- Goodarzi, Mark O.;
- Chen, Yii‐Der Ida;
- Peloso, Gina M.;
- Guo, Xiuqing
Publication type:
Article
Upregulated heme biosynthesis increases obstructive sleep apnea severity: a pathway-based Mendelian randomization study.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-05415-4
By:
- Wang, Heming;
- Kurniansyah, Nuzulul;
- Cade, Brian E.;
- Goodman, Matthew O.;
- Chen, Han;
- Gottlieb, Daniel J.;
- Gharib, Sina A.;
- Purcell, Shaun M.;
- Lin, Xihong;
- Saxena, Richa;
- Zhu, Xiaofeng;
- Durda, Peter;
- Tracy, Russel;
- Liu, Yongmei;
- Taylor, Kent D.;
- Johnson, W. Craig;
- Gabriel, Stacey;
- Smith, Joshua D.;
- Aguet, François;
- Ardlie, Kirstin
Publication type:
Article
Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32275-3
By:
- Tahir, Usman A.;
- Katz, Daniel H.;
- Avila-Pachecho, Julian;
- Bick, Alexander G.;
- Pampana, Akhil;
- Robbins, Jeremy M.;
- Yu, Zhi;
- Chen, Zsu-Zsu;
- Benson, Mark D.;
- Cruz, Daniel E.;
- Ngo, Debby;
- Deng, Shuliang;
- Shi, Xu;
- Zheng, Shuning;
- Eisman, Aaron S.;
- Farrell, Laurie;
- Hall, Michael E.;
- Correa, Adolfo;
- Tracy, Russell P.;
- Durda, Peter
Publication type:
Article
Lymphocyte activation gene-3-associated protein networks are associated with HDL-cholesterol and mortality in the Trans-omics for Precision Medicine program.
Published in:
Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03304-0
By:
- Manichaikul, Ani;
- Lin, Honghuang;
- Kang, Chansuk;
- Yang, Chaojie;
- Rich, Stephen S.;
- Taylor, Kent D.;
- Guo, Xiuqing;
- Rotter, Jerome I.;
- Craig Johnson, W.;
- Cornell, Elaine;
- Tracy, Russell P.;
- Peter Durda, J.;
- Liu, Yongmei;
- Vasan, Ramachandran S.;
- Adrienne Cupples, L.;
- Gerszten, Robert E.;
- Clish, Clary B.;
- Jain, Deepti;
- Conomos, Matthew P.;
- Blackwell, Thomas
Publication type:
Article
Peripheral Blood Mononuclear Cell Gene Expression Associated with Pulmonary Microvascular Perfusion: The Multi-Ethnic Study of Atherosclerosis Chronic Obstructive Pulmonary Disease.
Published in:
Annals of the American Thoracic Society, 2024, v. 21, n. 6, p. 884, doi. 10.1513/AnnalsATS.202305-417OC
By:
- Buschur, Kristina L.;
- Pottinger, Tess D.;
- Vogel-Claussen, Jens;
- Powell, Charles A.;
- Aguet, Francois;
- Allen, Norrina B.;
- Ardlie, Kristin;
- Bluemke, David A.;
- Durda, Peter;
- Hermann, Emilia A.;
- Hoffman, Eric A.;
- Lima, João A.C.;
- Liu, Yongmei;
- Malinsky, Daniel;
- Manichaikul, Ani;
- Motahari, Amin;
- Post, Wendy S.;
- Prince, Martin R.;
- Rich, Stephen S.;
- Rotter, Jerome I.
Publication type:
Article
Multi-ancestry epigenome-wide analyses identify methylated sites associated with aortic augmentation index in TOPMed MESA.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-44806-z
By:
- Hu, Xiaowei;
- Logan, Jeongok G.;
- Kwon, Younghoon;
- Lima, Joao A. C.;
- Jacobs, David R.;
- Duprez, Daniel;
- Brumback, Lyndia;
- Taylor, Kent D.;
- Durda, Peter;
- Johnson, W. Craig;
- Cornell, Elaine;
- Guo, Xiuqing;
- Liu, Yongmei;
- Tracy, Russell P.;
- Blackwell, Thomas W.;
- Papanicolaou, George;
- Mitchell, Gary F.;
- Rich, Stephen S.;
- Rotter, Jerome I.;
- Van Den Berg, David J.
Publication type:
Article
Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci.
Published in:
Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00877-z
By:
- Breeze, Charles E.;
- Batorsky, Anna;
- Lee, Mi Kyeong;
- Szeto, Mindy D.;
- Xu, Xiaoguang;
- McCartney, Daniel L.;
- Jiang, Rong;
- Patki, Amit;
- Kramer, Holly J.;
- Eales, James M.;
- Raffield, Laura;
- Lange, Leslie;
- Lange, Ethan;
- Durda, Peter;
- Liu, Yongmei;
- Tracy, Russ P.;
- Van Den Berg, David;
- Evans, Kathryn L.;
- Kraus, William E.;
- Shah, Svati
Publication type:
Article
Intake and Sources of Dietary Fiber, Inflammation, and Cardiovascular Disease in Older US Adults.
Published in:
JAMA Network Open, 2022, v. 5, n. 3, p. e225012, doi. 10.1001/jamanetworkopen.2022.5012
By:
- Shivakoti, Rupak;
- Biggs, Mary L.;
- Djoussé, Luc;
- Durda, Peter Jon;
- Kizer, Jorge R.;
- Psaty, Bruce;
- Reiner, Alex P.;
- Tracy, Russell P.;
- Siscovick, David;
- Mukamal, Kenneth J.
Publication type:
Article
Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans.
Published in:
Human Genetics, 2014, v. 133, n. 8, p. 985, doi. 10.1007/s00439-014-1439-z
By:
- Ellis, Jaclyn;
- Lange, Ethan;
- Li, Jin;
- Dupuis, Josee;
- Baumert, Jens;
- Walston, Jeremy;
- Keating, Brendan;
- Durda, Peter;
- Fox, Ervin;
- Palmer, Cameron;
- Meng, Yan;
- Young, Taylor;
- Farlow, Deborah;
- Schnabel, Renate;
- Marzi, Carola;
- Larkin, Emma;
- Martin, Lisa;
- Bis, Joshua;
- Auer, Paul;
- Ramachandran, Vasan
Publication type:
Article
IL-6 gene variation is associated with IL-6 and C-reactive protein levels but not cardiovascular outcomes in the Cardiovascular Health Study.
Published in:
Human Genetics, 2007, v. 122, n. 5, p. 485, doi. 10.1007/s00439-007-0428-x
By:
- Walston, Jeremy D.;
- Fallin, M.;
- Cushman, Mary;
- Lange, Leslie;
- Psaty, Bruce;
- Jenny, Nancy;
- Browner, Warren;
- Tracy, Russell;
- Durda, Peter;
- Reiner, Alex
Publication type:
Article
A Common SCN5A Variant Is Associated with PR Interval and Atrial Fibrillation Among African Americans.
Published in:
Journal of Cardiovascular Electrophysiology, 2014, v. 25, n. 11, p. 1150, doi. 10.1111/jce.12483
By:
- ILKHANOFF, LEONARD;
- ARKING, DAN E.;
- LEMAITRE, ROZENN N.;
- ALONSO, ALVARO;
- CHEN, LIN Y.;
- DURDA, PETER;
- HESSELSON, STEPHANIE E.;
- KERR, KATHLEEN F.;
- MAGNANI, JARED W.;
- MARCUS, GREGORY M.;
- SCHNABEL, RENATE B.;
- SMITH, J. GUSTAV;
- SOLIMAN, ELSAYED Z.;
- REINER, ALEXANDER P.;
- SOTOODEHNIA, NONA
Publication type:
Article
Association of Polymorphisms in the CRP Gene With Circulating C-Reactive Protein Levels and Cardiovascular Events.
Published in:
JAMA: Journal of the American Medical Association, 2006, v. 296, n. 22, p. 2703, doi. 10.1001/jama.296.22.2703
By:
- Lange, Leslie A.;
- Carlson, Christopher S.;
- Hindorff, Lucia A.;
- Lange, Ethan M.;
- Walston, Jeremy;
- Durda, J. Peter;
- Cushman, Mary;
- Bis, Joshua C.;
- Zeng, Donglin;
- Lin, Danyu;
- Kuller, Lewis H.;
- Nickerson, Deborah A.;
- Psaty, Bruce M.;
- Tracy, Russell P.;
- Reiner, Alexander P.
Publication type:
Article
Canonical correlation analysis for multi-omics: Application to cross-cohort analysis.
Published in:
PLoS Genetics, 2023, v. 19, n. 5, p. 1, doi. 10.1371/journal.pgen.1010517
By:
- Jiang, Min-Zhi;
- Aguet, François;
- Ardlie, Kristin;
- Chen, Jiawen;
- Cornell, Elaine;
- Cruz, Dan;
- Durda, Peter;
- Gabriel, Stacey B.;
- Gerszten, Robert E.;
- Guo, Xiuqing;
- Johnson, Craig W.;
- Kasela, Silva;
- Lange, Leslie A.;
- Lappalainen, Tuuli;
- Liu, Yongmei;
- Reiner, Alex P.;
- Smith, Josh;
- Sofer, Tamar;
- Taylor, Kent D.;
- Tracy, Russell P.
Publication type:
Article
Comparison of Proteomic Assessment Methods in Multiple Cohort Studies.
Published in:
Proteomics, 2020, v. 20, n. 12, p. 1, doi. 10.1002/pmic.201900278
By:
- Raffield, Laura M.;
- Dang, Hong;
- Pratte, Katherine A.;
- Jacobson, Sean;
- Gillenwater, Lucas A.;
- Ampleford, Elizabeth;
- Barjaktarevic, Igor;
- Basta, Patricia;
- Clish, Clary B.;
- Comellas, Alejandro P.;
- Cornell, Elaine;
- Curtis, Jeffrey L.;
- Doerschuk, Claire;
- Durda, Peter;
- Emson, Claire;
- Freeman, Christine M.;
- Guo, Xiuqing;
- Hastie, Annette T.;
- Hawkins, Gregory A.;
- Herrera, Julio
Publication type:
Article
Benchmarking association analyses of continuous exposures with RNA-seq in observational studies.
Published in:
Briefings in Bioinformatics, 2021, v. 22, n. 6, p. 1, doi. 10.1093/bib/bbab194
By:
- Sofer, Tamar;
- Kurniansyah, Nuzulul;
- Aguet, François;
- Ardlie, Kristin;
- Durda, Peter;
- Nickerson, Deborah A;
- Smith, Joshua D;
- Liu, Yongmei;
- Gharib, Sina A;
- Redline, Susan;
- Rich, Stephen S;
- Rotter, Jerome I;
- Taylor, Kent D
Publication type:
Article
Whole genome sequencing based analysis of inflammation biomarkers in the Trans-Omics for Precision Medicine (TOPMed) consortium.
Published in:
Human Molecular Genetics, 2024, v. 33, n. 16, p. 1429, doi. 10.1093/hmg/ddae050
By:
- Jiang, Min-Zhi;
- Gaynor, Sheila M;
- Li, Xihao;
- Buren, Eric Van;
- Stilp, Adrienne;
- Buth, Erin;
- Wang, Fei Fei;
- Manansala, Regina;
- Gogarten, Stephanie M;
- Li, Zilin;
- Polfus, Linda M;
- Salimi, Shabnam;
- Bis, Joshua C;
- Pankratz, Nathan;
- Yanek, Lisa R;
- Durda, Peter;
- Tracy, Russell P;
- Rich, Stephen S;
- Rotter, Jerome I;
- Mitchell, Braxton D
Publication type:
Article
Association of soluble interleukin‐2 receptor α and tumour necrosis factor receptor 1 with heart failure: The Multi‐Ethnic Study of Atherosclerosis.
Published in:
ESC Heart Failure, 2020, v. 7, n. 2, p. 639, doi. 10.1002/ehf2.12623
By:
- Bakhshi, Hooman;
- Varadarajan, Vinithra;
- Ambale‐Venkatesh, Bharath;
- Meyghani, Zahra;
- Ostovaneh, Mohammad R.;
- Durda, Peter;
- Wu, Colin O.;
- Tracy, Russell P.;
- Cushman, Mary;
- Bluemke, David A.;
- Lima, João A.C.
Publication type:
Article
Circulating Soluble CD163, Associations With Cardiovascular Outcomes and Mortality, and Identification of Genetic Variants in Older Individuals: The Cardiovascular Health Study.
Published in:
2022
By:
- Durda, Peter;
- Raffield, Laura M.;
- Lange, Ethan M.;
- Olson, Nels C.;
- Swords Jenny, Nancy;
- Cushman, Mary;
- Deichgraeber, Pia;
- Grarup, Niels;
- Jonsson, Anna;
- Hansen, Torben;
- Mychaleckyj, Josyf C.;
- Psaty, Bruce M.;
- Reiner, Alex P.;
- Tracy, Russell P.;
- Lange, Leslie A.;
- Jenny, Nancy Swords
Publication type:
journal article
Gene expression and splicing QTL analysis of blood cells in African American participants from the Jackson Heart Study.
Published in:
Genetics, 2024, v. 228, n. 1, p. 1, doi. 10.1093/genetics/iyae098
By:
- Wen, Jia;
- Sun, Quan;
- Huang, Le;
- Zhou, Lingbo;
- Doyle, Margaret F;
- Ekunwe, Lynette;
- Durda, Peter;
- Olson, Nels C;
- Reiner, Alexander P;
- Li, Yun;
- Raffield, Laura M
Publication type:
Article
Telomere shortening and the transition to family caregiving in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study.
Published in:
PLoS ONE, 2022, v. 17, n. 6, p. 1, doi. 10.1371/journal.pone.0268689
By:
- Armstrong, Nicole D.;
- Irvin, Marguerite R.;
- Haley, William E.;
- Blinka, Marcela D.;
- Kamin Mukaz, Debora;
- Patki, Amit;
- Rutherford Siegel, Sue;
- Shalev, Idan;
- Durda, Peter;
- Mathias, Rasika A.;
- Walston, Jeremy D.;
- Roth, David L.
Publication type:
Article
Protein prediction for trait mapping in diverse populations.
Published in:
PLoS ONE, 2022, p. 1, doi. 10.1371/journal.pone.0264341
By:
- Schubert, Ryan;
- Geoffroy, Elyse;
- Gregga, Isabelle;
- Mulford, Ashley J.;
- Aguet, Francois;
- Ardlie, Kristin;
- Gerszten, Robert;
- Clish, Clary;
- Van Den Berg, David;
- Taylor, Kent D.;
- Durda, Peter;
- Johnson, W. Craig;
- Cornell, Elaine;
- Guo, Xiuqing;
- Liu, Yongmei;
- Tracy, Russell;
- Conomos, Matthew;
- Blackwell, Tom;
- Papanicolaou, George;
- Lappalainen, Tuuli
Publication type:
Article
Factor V Leiden, prothrombin 20210A and the risk of venous thrombosis among cancer patients.
Published in:
British Journal of Haematology, 2005, v. 128, n. 3, p. 386, doi. 10.1111/j.1365-2141.2004.05327.x
By:
- Kennedy, Margaret;
- Andreescu, Astrid C. M.;
- Greenblatt, Marc S.;
- Jiang, Hongyu;
- Thomas, Christian A.;
- Chassereau, Laurie;
- Wong, Cheung;
- Durda, Peter;
- Cushman, Mary
Publication type:
Article
Clonal hematopoiesis associated with epigenetic aging and clinical outcomes.
Published in:
Aging Cell, 2021, v. 20, n. 6, p. 1, doi. 10.1111/acel.13366
By:
- Nachun, Daniel;
- Lu, Ake T.;
- Bick, Alexander G.;
- Natarajan, Pradeep;
- Weinstock, Joshua;
- Szeto, Mindy D.;
- Kathiresan, Sekar;
- Abecasis, Goncalo;
- Taylor, Kent D.;
- Guo, Xiuqing;
- Tracy, Russ;
- Durda, Peter;
- Liu, Yongmei;
- Johnson, Craig;
- Rich, Stephen S.;
- Van Den Berg, David;
- Laurie, Cecilia;
- Blackwell, Tom;
- Papanicolaou, George J.;
- Correa, Adolfo
Publication type:
Article
Multi-ancestry epigenome-wide analyses identify methylated sites associated with aortic augmentation index in TOPMed MESA.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-44806-z
By:
- Hu, Xiaowei;
- Logan, Jeongok G.;
- Kwon, Younghoon;
- Lima, Joao A. C.;
- Jacobs, David R.;
- Duprez, Daniel;
- Brumback, Lyndia;
- Taylor, Kent D.;
- Durda, Peter;
- Johnson, W. Craig;
- Cornell, Elaine;
- Guo, Xiuqing;
- Liu, Yongmei;
- Tracy, Russell P.;
- Blackwell, Thomas W.;
- Papanicolaou, George;
- Mitchell, Gary F.;
- Rich, Stephen S.;
- Rotter, Jerome I.;
- Van Den Berg, David J.
Publication type:
Article

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