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Targeting tumour-initiating cells to improve the cure rates for triple-negative breast cancer.
Published in:
Expert Reviews in Molecular Medicine, 2010, v. 12, n. 1, p. 1, doi. 10.1017/S1462399410001535
By:
- Stratford, Anna L.;
- Reipas, Kristen;
- Maxwell, Christopher;
- Dunn, Sandra E.
Publication type:
Article
YB-1: oncoprotein, prognostic marker and therapeutic target?
Published in:
Biochemical Journal, 2013, v. 449, n. 1, p. 11, doi. 10.1042/BJ20121323
By:
- LASHAM, Annette;
- PRINT, Cristin G.;
- WOOLLEY, Adele G.;
- DUNN, Sandra E.;
- BRAITHWAITE, Antony W.
Publication type:
Article
Concise Review: Bullseye: Targeting Cancer Stem Cells to Improve the Treatment of Gliomas by Repurposing Disulfiram.
Published in:
Stem Cells, 2015, v. 33, n. 4, p. 1042, doi. 10.1002/stem.1956
By:
- Triscott, Joanna;
- Rose Pambid, Mary;
- Dunn, Sandra E.
Publication type:
Article
YB-1 Transforms Human Mammary Epithelial Cells Through Chromatin Remodeling Leading to the Development of Basal-Like Breast Cancer.
Published in:
Stem Cells, 2014, v. 32, n. 6, p. 1437, doi. 10.1002/stem.1707
By:
- Davies, Alastair H.;
- Reipas, Kristen M.;
- Pambid, Mary Rose;
- Berns, Rachel;
- Stratford, Anna L.;
- Fotovati, Abbas;
- Firmino, Natalie;
- Astanehe, Arezoo;
- Hu, Kaiji;
- Maxwell, Christopher;
- Mills, Gordon B.;
- Dunn, Sandra E.
Publication type:
Article
FoxG1 Interacts with Bmi1 to Regulate Self-Renewal and Tumorigenicity of Medulloblastoma Stem Cells.
Published in:
Stem Cells, 2013, v. 31, n. 7, p. 1266, doi. 10.1002/stem.1401
By:
- Manoranjan, Branavan;
- Wang, Xin;
- Hallett, Robin M.;
- Venugopal, Chitra;
- Mack, Stephen C.;
- McFarlane, Nicole;
- Nolte, Sara M.;
- Scheinemann, Katrin;
- Gunnarsson, Thorsteinn;
- Hassell, John A.;
- Taylor, Michael D.;
- Lee, Cathy;
- Triscott, Joanna;
- Foster, Colleen M.;
- Dunham, Christopher;
- Hawkins, Cynthia;
- Dunn, Sandra E.;
- Singh, Sheila K.
Publication type:
Article
Targeting p90 Ribosomal S6 Kinase Eliminates Tumor-Initiating Cells by Inactivating Y-Box Binding Protein-1 in Triple-Negative Breast Cancers.
Published in:
Stem Cells, 2012, v. 30, n. 7, p. 1338, doi. 10.1002/stem.1128
By:
- Stratford, Anna L.;
- Reipas, Kristen;
- Hu, Kaiji;
- Fotovati, Abbas;
- Brough, Rachel;
- Frankum, Jessica;
- Takhar, Mandeep;
- Watson, Peter;
- Ashworth, Alan;
- Lord, Christopher J.;
- Lasham, Annette;
- Print, Cristin G.;
- Dunn, Sandra E.
Publication type:
Article
Polo-Like Kinase 1 Inhibition Kills Glioblastoma Multiforme Brain Tumor Cells in Part Through Loss of SOX2 and Delays Tumor Progression in Mice.
Published in:
Stem Cells, 2012, v. 30, n. 6, p. 1064, doi. 10.1002/stem.1081
By:
- Lee, Cathy;
- Fotovati, Abbas;
- Triscott, Joanna;
- Chen, James;
- Venugopal, Chitra;
- Singhal, Ash;
- Dunham, Christopher;
- Kerr, John M.;
- Verreault, Maite;
- Yip, Stephen;
- Wakimoto, Hiroaki;
- Jones, Chris;
- Jayanthan, Aarthi;
- Narendran, Aru;
- Singh, Sheila K.;
- Dunn, Sandra E.
Publication type:
Article
Molecular Decoy to the Y-Box Binding Protein-1 Suppresses the Growth of Breast and Prostate Cancer Cells whilst Sparing Normal Cell Viability.
Published in:
PLoS ONE, 2010, v. 5, n. 9, p. 1, doi. 10.1371/journal.pone.0012661
By:
- Law, Jennifer H.;
- Yvonne Li;
- To, Karen;
- Wang, Michelle;
- Astanehe, Arezoo;
- Lambie, Karen;
- Dhillon, Jaspreet;
- Jones, Steven J. M.;
- Gleave, Martin E.;
- Eaves, Connie J.;
- Dunn, Sandra E.
Publication type:
Article
Insulin-like growth factor-I: a key regulator of human cancer risk?
Published in:
1999
By:
- Burroughs, Kevin D.;
- Dunn, Sandra E.;
- Barrett, J. Carl;
- Taylor, Jack A.;
- Burroughs, K D;
- Dunn, S E;
- Barrett, J C;
- Taylor, J A
Publication type:
commentary
Akt phosphorylates the Y-box binding protein 1 at Ser102 located in the cold shock domain and affects the anchorage-independent growth of breast cancer cells.
Published in:
Oncogene, 2005, v. 24, n. 26, p. 4281, doi. 10.1038/sj.onc.1208590
By:
- Sutherland, Brent W;
- Kucab, Jill;
- Wu, Joyce;
- Lee, Cathy;
- Cheang, Maggie C U;
- Yorida, Erika;
- Turbin, Dmitry;
- Dedhar, Shoukat;
- Nelson, Colleen;
- Pollak, Michael;
- Leighton Grimes, H;
- Miller, Kathy;
- Badve, Sunil;
- Huntsman, David;
- Blake-Gilks, C;
- Chen, Min;
- Pallen, Catherine J;
- Dunn, Sandra E
Publication type:
Article
Small interfering RNA library screen identified polo-like kinase-1 (PLK1) as a potential therapeutic target for breast cancer that uniquely eliminates tumor-initiating cells.
Published in:
2012
By:
- Hu, Kaiji;
- Law, Jennifer H;
- Fotovati, Abbas;
- Dunn, Sandra E
Publication type:
journal article
Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress.
Published in:
Nature Communications, 2013, v. 4, n. 7, p. 2189, doi. 10.1038/ncomms3189
By:
- Gurkar, Aditi U.;
- Chu, Kiki;
- Raj, Lakshmi;
- Bouley, Richard;
- Lee, Seung-Hwan;
- Kim, Young-Bum;
- Dunn, Sandra E.;
- Mandinova, Anna;
- Lee, Sam W.
Publication type:
Article
Overcoming resistance to sonic hedgehog inhibition by targeting p90 ribosomal S6 kinase in pediatric medulloblastoma.
Published in:
Pediatric Blood & Cancer, 2014, v. 61, n. 1, p. 107, doi. 10.1002/pbc.24675
By:
- Pambid, Mary Rose;
- Berns, Rachel;
- Adomat, Hans H.;
- Hu, Kaiji;
- Triscott, Joanna;
- Maurer, Norbert;
- Zisman, Natalia;
- Ramaswamy, Vijay;
- Hawkins, Cynthia E.;
- Taylor, Michael D.;
- Dunham, Christopher;
- Guns, Emma;
- Dunn, Sandra E.
Publication type:
Article
EZH2 expression is a prognostic factor in childhood intracranial ependymoma: A Canadian Pediatric Brain Tumor Consortium study.
Published in:
Cancer (0008543X), 2015, v. 121, n. 9, p. 1499, doi. 10.1002/cncr.29198
By:
- Li, Amanda M.;
- Dunham, Christopher;
- Tabori, Uri;
- Carret, Anne‐Sophie;
- McNeely, P. Daniel;
- Johnston, Donna;
- Lafay‐Cousin, Lucie;
- Wilson, Beverly;
- Eisenstat, David D.;
- Jabado, Nada;
- Zelcer, Shayna;
- Silva, Mariana;
- Scheinemann, Katrin;
- Fryer, Christopher;
- Hendson, Glenda;
- Fotovati, Abbas;
- Hawkins, Cynthia;
- Yip, Stephen;
- Dunn, Sandra E.;
- Hukin, Juliette
Publication type:
Article
Y-box-binding protein 1 contributes to IL-7-mediated survival signaling in B-cell precursor acute lymphoblastic leukemia.
Published in:
Oncology Letters, 2017, v. 13, n. 1, p. 497, doi. 10.3892/ol.2016.5437
By:
- KARIMINIA, AMINA;
- IVISON, SABINE M.;
- LEUNG, VIVIAN M.;
- SUNG, SUSANNA;
- COUTO, NICOLE;
- ROZMUS, JACOB;
- ROLF, NINA;
- NARENDRAN, ARU;
- DUNN, SANDRA E.;
- REID, GREGOR S. D.;
- SCHULTZ, KIRK R.
Publication type:
Article
Cold shock Y-box protein-1 proteolysis autoregulates its transcriptional activities.
Published in:
Cell Communication & Signaling, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1478-811X-11-63
By:
- van Roeyen, Claudia R. C.;
- Scurt, Florian G.;
- Brandt, Sabine;
- Kuhl, Vanessa A.;
- Martinkus, Sandra;
- Djudjaj, Sonja;
- Raffetseder, Ute;
- Royer, Hans-Dieter;
- Stefanidis, Ioannis;
- Dunn, Sandra E.;
- Dooley, Steven;
- Honglei Weng;
- Fischer, Thomas;
- Lindquist, Jonathan A.;
- Mertens, Peter R.
Publication type:
Article
Stem Cells in Brain Tumour Development and Therapy- Two-Sides of the Same Coin.
Published in:
Canadian Journal of Neurological Sciences, 2012, v. 39, n. 2, p. 145, doi. 10.1017/S0317167100013159
By:
- Lee, Cathy;
- Dunn, Sandra E.;
- Yip, Stephen
Publication type:
Article

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