Found: 17

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  • The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage.

    Published in:
    eLife, 2017, p. 1, doi. 10.7554/eLife.23872.001
    By:
    • Kitevski-LeBlanc, Julianne;
    • Fradet-Turcotte, Amélie;
    • Kukic, Predrag;
    • Wilson, Marcus D.;
    • Portella, Guillem;
    • Tairan Yuwen;
    • Panier, Stephanie;
    • Shili Duan;
    • Canny, Marella D.;
    • van Ingen, Hugo;
    • Arrowsmith, Cheryl H.;
    • Rubinstein, John L.;
    • Vendruscolo, Michele;
    • Durocher, Daniel;
    • Kay, Lewis E.
    Publication type:
    Article

  • Molecular basis of Pirh2-mediated p53 ubiquitylation.

    Published in:
    Nature Structural & Molecular Biology, 2008, v. 15, n. 12, p. 1334, doi. 10.1038/nsmb.1521
    By:
    • Sheng, Yi;
    • Laister, Rob C.;
    • Lemak, Alexander;
    • Wu, Bin;
    • Tai, Elizabeth;
    • Duan, Shili;
    • Lukin, Jonathan;
    • Sunnerhagen, Maria;
    • Srisailam, Sampath;
    • Karra, Murthy;
    • Benchimol, Sam;
    • Arrowsmith, Cheryl H.
    Publication type:
    Article

  • Molecular recognition of p53 and MDM2 by USP7/HAUSP.

    Published in:
    Nature Structural & Molecular Biology, 2006, v. 13, n. 3, p. 285, doi. 10.1038/nsmb1067
    By:
    • Yi Sheng;
    • Saridakis, Vivian;
    • Sarkari, Feroz;
    • Duan, Shili;
    • Tianne Wu;
    • Arrowsmith, Cheryl H.;
    • Frappier, Lori
    Publication type:
    Article

  • Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations.

    Published in:
    PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083737
    By:
    • Wu, Hong;
    • Zeng, Hong;
    • Dong, Aiping;
    • Li, Fengling;
    • He, Hao;
    • Senisterra, Guillermo;
    • Seitova, Alma;
    • Duan, Shili;
    • Brown, Peter J.;
    • Vedadi, Masoud;
    • Arrowsmith, Cheryl H.;
    • Schapira, Matthieu
    Publication type:
    Article

  • A chemical toolbox for the study of bromodomains and epigenetic signaling.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09672-2
    By:
    • Wu, Qin;
    • Heidenreich, David;
    • Zhou, Stanley;
    • Ackloo, Suzanne;
    • Krämer, Andreas;
    • Nakka, Kiran;
    • Lima-Fernandes, Evelyne;
    • Deblois, Genevieve;
    • Duan, Shili;
    • Vellanki, Ravi N.;
    • Li, Fengling;
    • Vedadi, Masoud;
    • Dilworth, Jeffrey;
    • Lupien, Mathieu;
    • Brennan, Paul E.;
    • Arrowsmith, Cheryl H.;
    • Müller, Susanne;
    • Fedorov, Oleg;
    • Filippakopoulos, Panagis;
    • Knapp, Stefan
    Publication type:
    Article

  • Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09309-4
    By:
    • Lima-Fernandes, Evelyne;
    • Murison, Alex;
    • da Silva Medina, Tiago;
    • Wang, Yadong;
    • Ma, Anqi;
    • Leung, Cherry;
    • Luciani, Genna M.;
    • Haynes, Jennifer;
    • Pollett, Aaron;
    • Zeller, Constanze;
    • Duan, Shili;
    • Kreso, Antonija;
    • Barsyte-Lovejoy, Dalia;
    • Wouters, Bradly G.;
    • Jin, Jian;
    • Carvalho, Daniel D. De;
    • Lupien, Mathieu;
    • Arrowsmith, Cheryl H.;
    • O'Brien, Catherine A.
    Publication type:
    Article

  • Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1.

    Published in:
    Nature, 2008, v. 455, n. 7214, p. 822, doi. 10.1038/nature07273
    By:
    • Avvakumov, George V.;
    • Walker, John R.;
    • Sheng Xue;
    • Yanjun Li;
    • Shili Duan;
    • Bronner, Christian;
    • Arrowsmith, Cheryl H.;
    • Dhe-Paganon, Sirano
    Publication type:
    Article

  • RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.

    Published in:
    2021
    By:
    • Patel, Parasvi S.;
    • Abraham, Karan Joshua;
    • Naidu Guturi, Kiran Kumar;
    • Halaby, Marie-Jo;
    • Khan, Zahra;
    • Palomero, Luis;
    • Ho, Brandon;
    • Duan, Shili;
    • St-Germain, Jonathan;
    • Algouneh, Arash;
    • Mateo, Francesca;
    • El Ghamrasni, Samah;
    • Barbour, Haithem;
    • Barnes, Daniel R.;
    • Beesley, Jonathan;
    • Sanchez, Otto;
    • Berman, Hal K.;
    • Brown, Grant W.;
    • Affar, El Bachir;
    • Chenevix-Trench, Georgia
    Publication type:
    journal article

  • Characterization of a family of vacuolar Na<sup>+</sup>/H<sup>+</sup> antiporters in Arabidopsis thaliana.

    Published in:
    Plant & Soil, 2003, v. 253, n. 1, p. 245, doi. 10.1023/A:1024577205697
    By:
    • Aharon, Gilad S.;
    • Apse, Maris P.;
    • Duan, Shili;
    • Hua, Xuejun;
    • Blumwald, Eduardo
    Publication type:
    Article

  • RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.

    Published in:
    Nucleic Acids Research, 2023, v. 51, n. 19, p. 10484, doi. 10.1093/nar/gkad733
    By:
    • Krishnan, Rehna;
    • Lapierre, Mariah;
    • Gautreau, Brandon;
    • Nixon, Kevin C J;
    • El Ghamrasni, Samah;
    • Patel, Parasvi S;
    • Hao, Jun;
    • Yerlici, V Talya;
    • Guturi, Kiran Kumar Naidu;
    • St-Germain, Jonathan;
    • Mateo, Francesca;
    • Saad, Amine;
    • Algouneh, Arash;
    • Earnshaw, Rebecca;
    • Shili, Duan;
    • Seitova, Alma;
    • Miller, Joshua;
    • Khosraviani, Negin;
    • Penn, Adam;
    • Ho, Brandon
    Publication type:
    Article

  • MYC oncoprotein directly interacts with its chromatin cofactor PNUTS to recruit PP1 phosphatase.

    Published in:
    Nucleic Acids Research, 2022, v. 50, n. 6, p. 3505, doi. 10.1093/nar/gkac138
    By:
    • Wei, Yong;
    • Redel, Cornelia;
    • Ahlner, Alexandra;
    • Lemak, Alexander;
    • Johansson-Åkhe, Isak;
    • Houliston, Scott;
    • Kenney, Tristan M G;
    • Tamachi, Aaliya;
    • Morad, Vivian;
    • Duan, Shili;
    • Andrews, David W;
    • Wallner, Björn;
    • Sunnerhagen, Maria;
    • Arrowsmith, Cheryl H;
    • Penn, Linda Z
    Publication type:
    Article

  • Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1.

    Published in:
    Nucleic Acids Research, 2020, v. 48, n. 14, p. 7728, doi. 10.1093/nar/gkaa520
    By:
    • Tauber, Maria;
    • Kreuz, Sarah;
    • Lemak, Alexander;
    • Mandal, Papita;
    • Yerkesh, Zhadyra;
    • Veluchamy, Alaguraj;
    • Al-Gashgari, Bothayna;
    • Aljahani, Abrar;
    • Cortés-Medina, Lorena V;
    • Azhibek, Dulat;
    • Fan, Lixin;
    • Ong, Michelle S;
    • Duan, Shili;
    • Houliston, Scott;
    • Arrowsmith, Cheryl H;
    • Fischle, Wolfgang
    Publication type:
    Article

  • The MLL1 trimeric catalytic complex is a dynamic conformational ensemble stabilized by multiple weak interactions.

    Published in:
    Nucleic Acids Research, 2019, v. 47, n. 17, p. 9433, doi. 10.1093/nar/gkz697
    By:
    • Kaustov, Lilia;
    • Lemak, Alexander;
    • Wu, Hong;
    • Faini, Marco;
    • Fan, Lixin;
    • Fang, Xianyang;
    • Zeng, Hong;
    • Duan, Shili;
    • Allali-Hassani, Abdellah;
    • Li, Fengling;
    • Wei, Yong;
    • Vedadi, Masoud;
    • Aebersold, Ruedi;
    • Wang, Yunxing;
    • Houliston, Scott;
    • Arrowsmith, Cheryl H
    Publication type:
    Article

  • Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.

    Published in:
    Nucleic Acids Research, 2019, v. 47, n. 3, p. 1225, doi. 10.1093/nar/gky1192
    By:
    • Ivanochko, Danton;
    • Halabelian, Levon;
    • Henderson, Elizabeth;
    • Savitsky, Pavel;
    • Jain, Harshika;
    • Marcon, Edyta;
    • Duan, Shili;
    • Hutchinson, Ashley;
    • Seitova, Alma;
    • Barsyte-Lovejoy, Dalia;
    • Filippakopoulos, Panagis;
    • Greenblatt, Jack;
    • Lima-Fernandes, Evelyne;
    • Arrowsmith, Cheryl H
    Publication type:
    Article

  • Role of Pirh2 in Mediating the Regulation of p53 and c-Myc.

    Published in:
    PLoS Genetics, 2011, v. 7, n. 11, p. 1, doi. 10.1371/journal.pgen.1002360
    By:
    • Hakem, Anne;
    • Bohgaki, Miyuki;
    • Lemmers, Bénédicte;
    • Tai, Elisabeth;
    • Salmena, Leonardo;
    • Matysiak-Zablocki, Elzbieta;
    • Yong-Sam Jung;
    • Karaskova, Jana;
    • Kaustov, Lilia;
    • Duan, Shili;
    • Madore, Jason;
    • Boutros, Paul;
    • Yi Sheng;
    • Chesi, Marta;
    • Bergsagel, P. Leif;
    • Perez-Ordonez, Bayardo;
    • Mes-Masson, Anne-Marie;
    • Penn, Linda;
    • Squire, Jeremy;
    • Xinbin Chen
    Publication type:
    Article

  • Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain.

    Published in:
    Nature Chemical Biology, 2013, v. 9, n. 3, p. 184, doi. 10.1038/nchembio.1157
    By:
    • James, Lindsey I;
    • Barsyte-Lovejoy, Dalia;
    • Zhong, Nan;
    • Krichevsky, Liubov;
    • Korboukh, Victoria K;
    • Herold, J Martin;
    • MacNevin, Christopher J;
    • Norris, Jacqueline L;
    • Sagum, Cari A;
    • Tempel, Wolfram;
    • Marcon, Edyta;
    • Guo, Hongbo;
    • Gao, Cen;
    • Huang, Xi-Ping;
    • Duan, Shili;
    • Emili, Andrew;
    • Greenblatt, Jack F;
    • Kireev, Dmitri B;
    • Jin, Jian;
    • Janzen, William P
    Publication type:
    Article

  • GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18020-8
    By:
    • Wu, Qin;
    • ba-alawi, Wail;
    • Deblois, Genevieve;
    • Cruickshank, Jennifer;
    • Duan, Shili;
    • Lima-Fernandes, Evelyne;
    • Haight, Jillian;
    • Tonekaboni, Seyed Ali Madani;
    • Fortier, Anne-Marie;
    • Kuasne, Hellen;
    • McKee, Trevor D.;
    • Mahmoud, Hassan;
    • Kushida, Michelle;
    • Cameron, Sarina;
    • Dogan-Artun, Nergiz;
    • Chen, WenJun;
    • Nie, Yan;
    • Zhang, Lan Xin;
    • Vellanki, Ravi N.;
    • Zhou, Stanley
    Publication type:
    Article