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What are the properties that make an antibiotic acceptable for therapy of community-acquired pneumonia?
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2011, v. 66, n. suppl_3, p. iii61, doi. 10.1093/jac/dkr100
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- Publication type:
- Article
Determination of antibiotic dosage adjustments in patients with renal impairment: elements for success.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2010, v. 65, n. 11, p. 2285, doi. 10.1093/jac/dkq323
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- Publication type:
- Article
Pharmacodynamics of ceftaroline fosamil for complicated skin and skin structure infection: rationale for improved anti-methicillin-resistant Staphylococcus aureus activity.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2010, v. 65, n. suppl_4, p. iv33, doi. 10.1093/jac/dkq253
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- Publication type:
- Article
Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2005, v. 55, n. 5, p. 601, doi. 10.1093/jac/dki079
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- Publication type:
- Article
Pharmacodynamics of cefepime in patients with Gram-negative infections.
- Published in:
- 2002
- By:
- Publication type:
- journal article
Optimizing the Use of Beta-Lactam Antibiotics in Clinical Practice: A Test of Time.
- Published in:
- Open Forum Infectious Diseases, 2023, v. 10, n. 7, p. 1, doi. 10.1093/ofid/ofad305
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- Publication type:
- Article
Pharmacodynamic Evaluation of Zoliflodacin Treatment of Neisseria gonorrhoeae Strains With Amino Acid Substitutions in the Zoliflodacin Target GyrB Using a Dynamic Hollow Fiber Infection Model.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1035841
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- Publication type:
- Article
Optimal Sampling Theory and Population Modelling: Application to Determination of the Influence of the Microgravity Environment on Drug Distribution and Elimination.
- Published in:
- 1991
- By:
- Publication type:
- Other
Inoculum-Based Dosing: A Novel Concept for Combining Time with Concentration-Dependent Antibiotics to Optimize Clinical and Microbiological Outcomes in Severe Gram Negative Sepsis.
- Published in:
- Antibiotics (2079-6382), 2023, v. 12, n. 11, p. 1581, doi. 10.3390/antibiotics12111581
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- Publication type:
- Article
Relationship between dideoxyinosine exposure, CD4 counts, and p24 antigen levels in human immunodeficiency virus infection. A phase I trial.
- Published in:
- 1992
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- Publication type:
- journal article
Cefoxitin--Resistant Facultative or Aerobic Gram--Negative Bacilli in Infections Associated with the Gastrointestinal Tract.
- Published in:
- Annals of Internal Medicine, 1981, v. 94, n. 4, p. 487, doi. 10.7326/0003-4819-94-4-487
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- Publication type:
- Article
Surface Response Modeling to Examine the Combination of Amphotericin B Deoxycholate and 5-Fluorocytosine for Treatment of Invasive Candidiasis.
- Published in:
- Journal of Infectious Diseases, 2005, v. 192, n. 4, p. 673, doi. 10.1086/432069
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- Publication type:
- Article
Bacterial-Population Responses to Drug-Selective Pressure: Examination of Garenoxacin's Effect on Pseudomonas aeruginosa.
- Published in:
- Journal of Infectious Diseases, 2005, v. 192, n. 3, p. 420, doi. 10.1086/430611
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- Publication type:
- Article
Clearance Duration as a Predictor of Sustained Viral Response in Patients with Chronic Hepatitis C Virus Genotype 1.
- Published in:
- 2005
- By:
- Publication type:
- Letter
Relationship between Fluoroquinolone Area under the Curve: Minimum Inhibitory Concentration Ratio and the Probability of Eradication of the Infecting Pathogen, in Patients with Nosocomial Pneumonia.
- Published in:
- Journal of Infectious Diseases, 2004, v. 189, n. 9, p. 1590, doi. 10.1086/383320
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- Publication type:
- Article
The Safety and Efficacy of Granulocyte-Macrophage Colony-Stimulating Factor (Sargramostim) Added to Indinavir- or Ritonavir-Based Antiretroviral Therapy: A Randomized Double-Blind, Placebo-Controlled Trial.
- Published in:
- Journal of Infectious Diseases, 1999, v. 180, n. 4, p. 1064, doi. 10.1086/314981
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- Publication type:
- Article
Correlation of Quantitative Bone Marrow and Blood Cultures in AIDS Patients with Disseminated Mycobacterium avium Complex Infection.
- Published in:
- Journal of Infectious Diseases, 1999, v. 180, n. 2, doi. 10.1086/314865
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- Publication type:
- Article
Relevance of Plasma Protein Binding to Antiviral Activity and Clinical Efficacy of Inhibitors of Human Immunodeficiency Virus Protease.
- Published in:
- Journal of Infectious Diseases, 1996, v. 173, n. 6, p. 1524, doi. 10.1093/infdis/173.6.1524
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- Publication type:
- Article
Soluble Tumor Necrosis Factor-α Receptor Type II (sTNFαRII) Correlates with Human Immunodeficiency Virus (HIV) RNA Copy Number in HIV-Infected Patients.
- Published in:
- Journal of Infectious Diseases, 1996, v. 173, n. 2, p. 464
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- Publication type:
- Article
Pharmacodynamic Evaluation of Dosing, Bacterial Kill, and Resistance Suppression for Zoliflodacin Against Neisseria gonorrhoeae in a Dynamic Hollow Fiber Infection Model.
- Published in:
- Frontiers in Pharmacology, 2021, v. 11, p. 1, doi. 10.3389/fphar.2021.682135
- By:
- Publication type:
- Article
Individualized Patient Care Through Model-Informed Precision Dosing: Reflections on Training Future Practitioners.
- Published in:
- AAPS Journal, 2022, v. 24, n. 6, p. 1, doi. 10.1208/s12248-022-00769-z
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- Publication type:
- Article
Analysis of Combination Drug Therapy to Develop Regimens with Shortened Duration of Treatment for Tuberculosis.
- Published in:
- PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0101311
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- Publication type:
- Article
Chikungunya Virus: In Vitro Response to Combination Therapy With Ribavirin and Interferon Alfa 2a.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Combination Treatment With Meropenem Plus Levofloxacin Is Synergistic Against Pseudomonas aeruginosa Infection in a Murine Model of Pneumonia.
- Published in:
- Journal of Infectious Diseases, 2015, v. 211, n. 8, p. 1326, doi. 10.1093/infdis/jiu603
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- Publication type:
- Article
Interaction of Drug- and Granulocyte-Mediated Killing of Pseudomonas aeruginosa in a Murine Pneumonia Model.
- Published in:
- Journal of Infectious Diseases, 2014, v. 210, n. 8, p. 1319, doi. 10.1093/infdis/jiu237
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- Publication type:
- Article
The Pharmacokinetics and Pharmacodynamics of Micafungin in Experimental Hematogenous Candida Meningoencephalitis: Implications for Echinocandin Therapy in Neonates.
- Published in:
- Journal of Infectious Diseases, 2008, v. 197, n. 1, p. 163, doi. 10.1086/524063
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- Publication type:
- Article
Comparison of 2 Antibiotics That Inhibit Protein Synthesis for the Treatment of Infection with Yersinia pestis Delivered by Aerosol in a Mouse Model of Pneumonic Plague.
- Published in:
- Journal of Infectious Diseases, 2007, v. 196, n. 5, p. 782, doi. 10.1086/520547
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- Publication type:
- Article
Reply to Wallis et al. and Mitchison et al.
- Published in:
- 2007
- By:
- Publication type:
- Letter
Isoniazid's Bactericidal Activity Ceases because of the Emergence of Resistance, Not Depletion of Mycobacterium tuberculosis in the Log Phase of Growth.
- Published in:
- Journal of Infectious Diseases, 2007, v. 195, n. 2, p. 194, doi. 10.1086/510247
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- Publication type:
- Article
Sex differences in CYP3A activity using intravenous and oral midazolam<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2006, v. 80, n. 5, p. 531, doi. 10.1016/j.clpt.2006.08.014
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- Publication type:
- Article
Population pharmacokinetics of zidovudine.
- Published in:
- Clinical Pharmacology & Therapeutics, 1990, v. 48, n. 2, p. 161, doi. 10.1038/clpt.1990.131
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- Publication type:
- Article
Prospective use of optimal sampling theory: Steady-state ciprofloxacin pharmacokinetics in critically ill trauma patients.
- Published in:
- Clinical Pharmacology & Therapeutics, 1989, v. 46, n. 4, p. 451, doi. 10.1038/clpt.1989.164
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- Publication type:
- Article
A prospective evaluation of optimal sampling theory in the determination of the steady-state pharmacokinetics of piperacillin in febrile neutropenic cancer patients.
- Published in:
- Clinical Pharmacology & Therapeutics, 1989, v. 45, n. 6, p. 635, doi. 10.1038/clpt.1989.84
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- Publication type:
- Article
An evaluation of optimal sampling strategy and adaptive study design.
- Published in:
- Clinical Pharmacology & Therapeutics, 1988, v. 44, n. 2, p. 232, doi. 10.1038/clpt.1988.142
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- Publication type:
- Article
Integration of Population Pharmacokinetics, a Pharmacodynamic Target, and Microbiological Surveillance Data to Generate a Rational Empiric Dosing Strategy for Cefepime against Pseudomonas aeruginosa.
- Published in:
- Pharmacotherapy, 2003, v. 23, n. 3, p. 291, doi. 10.1592/phco.23.3.291.32110
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- Publication type:
- Article
Prevalence of Drug-Resistant and Nonsubtype B HIV Strains in Antiretroviral-Naïve, HIV-Infected Individuals in New York State.
- Published in:
- AIDS Patient Care & STDs, 2007, v. 21, n. 9, p. 644, doi. 10.1089/apc.2006.0172
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- Publication type:
- Article
Pharmacodynamic Modeling of Anti-Cancer Activity of Tetraiodothyroacetic Acid in a Perfused Cell Culture System.
- Published in:
- PLoS Computational Biology, 2011, v. 7, n. 2, p. 1, doi. 10.1371/journal.pcbi.1001073
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- Publication type:
- Article
Combination Therapy with UV-4B and Molnupiravir Enhances SARS-CoV-2 Suppression.
- Published in:
- Viruses (1999-4915), 2023, v. 15, n. 5, p. 1175, doi. 10.3390/v15051175
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- Publication type:
- Article
Antiviral Effects of Clinically-Relevant Interferon-α and Ribavirin Regimens against Dengue Virus in the Hollow Fiber Infection Model (HFIM).
- Published in:
- Viruses (1999-4915), 2018, v. 10, n. 6, p. 317, doi. 10.3390/v10060317
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- Publication type:
- Article
Pharmacodynamics of levofloxacin.
- Published in:
- JAMA: Journal of the American Medical Association, 1998, v. 279, n. 2, p. 125, doi. 10.1001/jama.279.2.125
- By:
- Publication type:
- Article
"One-Two Punch": Synergistic ß-Lactam Combinations for Mycobacterium abscessus and Target Redundancy in the Inhibition of Peptidoglycan Synthesis Enzymes.
- Published in:
- Clinical Infectious Diseases, 2021, v. 73, n. 8, p. 1532, doi. 10.1093/cid/ciab535
- By:
- Publication type:
- Article
Vancomycin Area Under the Curve–Guided Dosing and Monitoring for Adult and Pediatric Patients With Suspected or Documented Serious Methicillin-Resistant Staphylococcus aureus Infections: Putting the Safety of Our Patients First.
- Published in:
- Clinical Infectious Diseases, 2021, v. 72, n. 9, p. 1497, doi. 10.1093/cid/ciaa1744
- By:
- Publication type:
- Article
Development of New Antimicrobials for Urogenital Gonorrhea Therapy: Clinical Trial Design Considerations.
- Published in:
- Clinical Infectious Diseases, 2020, v. 70, n. 7, p. 1495, doi. 10.1093/cid/ciz899
- By:
- Publication type:
- Article
Vancomycin Exposure in Patients With Methicillin-Resistant Staphylococcus aureus Bloodstream Infections: How Much Is Enough?
- Published in:
- Clinical Infectious Diseases, 2014, v. 59, n. 5, p. 666, doi. 10.1093/cid/ciu398
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- Publication type:
- Article
In Memoriam: John P. Quinn, MD.
- Published in:
- 2014
- By:
- Publication type:
- Obituary
Comparative Pharmacokinetics and Renal Effects of Cyclosporin A and Cyclosporin G in Renal Allograft Recipients.
- Published in:
- 1997
- By:
- Publication type:
- Other
Nonparametric Expectation Maximization Population Modeling of Ganciclovir.
- Published in:
- 1996
- By:
- Publication type:
- Other
Application of Antimicrobial Pharmacodynamic Concepts into Clinical Practice: Focus on β-Lactam Antibiotics.
- Published in:
- Pharmacotherapy, 2006, v. 26, n. 9, p. 1320, doi. 10.1592/phco.26.9.1320
- By:
- Publication type:
- Article
Infection Site Concentrations: Their Therapeutic Importance and the Macrolide and Macrolide-Like Class of Antibiotics.
- Published in:
- Pharmacotherapy, 2005, v. 25, p. 150S, doi. 10.1592/phco.2005.25.12part2.150S
- By:
- Publication type:
- Article
Comparative Pharmacokinetic Analysis by Standard Two-Stage Method versus Nonparametric Population Modeling.
- Published in:
- Pharmacotherapy, 2003, v. 23, n. 12, p. 1545, doi. 10.1592/phco.23.15.1545.31969
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- Publication type:
- Article