Works by Drucker, Daniel J.

Results: 134

Chemical characterization of leptin-activated neurons in the rat brain.

Published in:

Journal of Comparative Neurology, 2000, v. 423, n. 2, p. 261, doi. 10.1002/1096-9861(20000724)423:2<261::AID-CNE6>3.0.CO;2-6

By:

Elias, Carol F.;
Kelly, Joseph F.;
Lee, Charlotte E.;
Ahima, Rexford S.;
Drucker, Daniel J.;
Saper, Clifford B.;
Elmquist, Joel K.

Publication type:

Article

Glucagon-Like Peptide-1 Is Involved in the Thermic Effects of Dietary Proteins in Male Rodents.

Published in:

Endocrinology, 2023, v. 164, n. 6, p. 1, doi. 10.1210/endocr/bqad068

By:

Ochiai, Keita;
Muto, Asuka;
Seok, Bong Soo;
Doi, Yuta;
Iwasaki, Yusaku;
Okamatsu-Ogura, Yuko;
Drucker, Daniel J;
Hira, Tohru

Publication type:

Article

GLP-1 Receptor Signaling Differentially Modifies the Outcomes of Sterile vs Viral Pulmonary Inflammation in Male Mice.

Published in:

Endocrinology, 2020, v. 161, n. 12, p. 1, doi. 10.1210/endocr/bqaa201

By:

Sato, Takehiro;
Shimizu, Tatsunori;
Fujita, Hiroki;
Imai, Yumiko;
Drucker, Daniel J;
Seino, Yutaka;
Yamada, Yuichiro

Publication type:

Article

Proglucagon-Derived Peptides, Glucose-Dependent Insulinotropic Polypeptide, and Dipeptidyl Peptidase-4-Mechanisms of Action in Adipose Tissue.

Published in:

Endocrinology, 2020, v. 161, n. 1, p. 1, doi. 10.1210/endocr/bqz029

By:

Beaudry, Jacqueline L;
Drucker, Daniel J

Publication type:

Article

Localization of Glucagon-Like Peptide-2 Receptor Expression in the Mouse.

Published in:

Endocrinology, 2019, v. 160, n. 8, p. 1950, doi. 10.1210/en.2019-00398

By:

Yusta, Bernardo;
Matthews, Dianne;
Koehler, Jacqueline A;
Pujadas, Gemma;
Kaur, Kiran Deep;
Drucker, Daniel J

Publication type:

Article

GLP-1 Receptor Expression Within the Human Heart.

Published in:

Endocrinology, 2018, v. 159, n. 4, p. 1570, doi. 10.1210/en.2018-00004

By:

Baggio, Laurie L;
Yusta, Bernardo;
Mulvihill, Erin E;
Cao, Xiemin;
Streutker, Catherine J;
Butany, Jagdish;
Cappola, Thomas P;
Margulies, Kenneth B;
Drucker, Daniel J

Publication type:

Article

Glucagon-Like Peptide-1-Responsive Catecholamine Neurons in the Area Postrema Link Peripheral Glucagon-Like Peptide-1 with Central Autonomic Control Sites.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 7, p. 2939, doi. 10.1523/JNEUROSCI.23-07-02939.2003

By:

Yamamoto, Hiroshi;
Kishi, Toshiro;
Lee, Charlotte E.;
Choi, Brian J.;
Fang, Hui;
Hollenberg, Anthony N.;
Drucker, Daniel J.;
Elmquist, Joel K.

Publication type:

Article

Efficacy and Safety of GLP-1 Medicines for Type 2 Diabetes and Obesity.

Published in:

Diabetes Care, 2024, v. 47, n. 11, p. 1873, doi. 10.2337/dci24-0003

By:

Drucker, Daniel J.

Publication type:

Article

Bernard Zinman: A Canadian Clinician Scientist Changing the Management of Diabetes.

Published in:

Diabetes Care, 2022, v. 45, n. 8, p. 1709, doi. 10.2337/dci22-0017

By:

Drucker, Daniel J.

Publication type:

Article

Erratum. Dipeptidyl Peptidase 4 Inhibition Stimulates Distal Tubular Natriuresis and Increases in Circulating SDF-1α<sup>1-67</sup> in Patients With Type 2 Diabetes. Diabetes Care 2017;40:1073-1081.

Published in:

2017

By:

Lovshin, Julie A;
Rajasekeran, Harindra;
Lytvyn, Yulyia;
Lovblom, Leif E;
Khan, Shajiha;
Alemu, Robel;
Locke, Amy;
Lai, Vesta;
He, Huaibing;
Hittle, Lucinda;
Wang, Weixun;
Drucker, Daniel J;
Cherney, David Z I

Publication type:

journal article

Dipeptidyl Peptidase 4 Inhibition Stimulates Distal Tubular Natriuresis and Increases in Circulating SDF-1α<sup>1-67</sup> in Patients With Type 2 Diabetes.

Published in:

2017

By:

Lovshin, Julie A.;
Rajasekeran, Harindra;
Lytvyn, Yulyia;
Lovblom, Leif E.;
Khan, Shajiha;
Alemu, Robel;
Locke, Amy;
Lai, Vesta;
He, Huaibing;
Hittle, Lucinda;
Weixun Wang;
Drucker, Daniel J.;
Cherney, David Z. I.;
Wang, Weixun

Publication type:

journal article

Discovery, characterization, and clinical development of the glucagon-like peptides.

Published in:

2017

By:

Drucker, Daniel J.;
Habener, Joel F.;
Holst, Jens Juul

Publication type:

journal article

Glucagon-like peptide-1 receptors in the brain: controlling food intake and body weight.

Published in:

2014

By:

Baggio, Laurie L.;
Drucker, Daniel J.

Publication type:

journal article

Pancreatic GLP-1 receptor activation is sufficient for incretin control of glucose metabolism in mice.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 1, p. 388, doi. 10.1172/JCI42497

By:

Lamont, Benjamin J.;
Yazhou Li;
Kwan, Edwin;
Brown, Theodore J.;
Gaisano, Herbert;
Drucker, Daniel J.

Publication type:

Article

Dual elimination of the glucagon and GLP-1 receptors in mice reveals plasticity in the incretin axis.

Published in:

2011

By:

Ali, Safina;
Lamont, Benjamin J.;
Charron, Maureen J.;
Drucker, Daniel J.

Publication type:

journal article

Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditure.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 1, p. 143, doi. 10.1172/JCI25483

By:

Hansotia, Tanya;
Maida, Adriano;
Flock, Grace;
Yamada, Yuichiro;
Tsukiyama, Katsushi;
Seino, Yutaka;
Drucker, Daniel J.

Publication type:

Article

The role of gut hormones in glucose homeostasis.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 1, p. 24, doi. 10.1172/JCI30076

By:

Drucker, Daniel J.

Publication type:

Article

Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage.

Published in:

2005

By:

Knauf, Claude;
Cani, Patrice D.;
Perrin, Christophe;
Iglesias, Miguel A.;
Maury, Jean François;
Bernard, Elodie;
Benhamed, Fadilha;
Grémeaux, Thierry;
Drucker, Daniel J.;
Kahn, C. Ronald;
Girard, Jean;
Tanti, Jean François;
Delzenne, Nathalie M.;
Postic, Catherine;
Burcelin, Rémy;
Maury, Jean François;
Grémeaux, Thierry;
Tanti, Jean François;
Burcelin, Rémy

Publication type:

journal article

Liraglutide Promotes Natriuresis but Does Not Increase Circulating Levels of Atrial Natriuretic Peptide in Hypertensive Subjects With Type 2 Diabetes.

Published in:

Diabetes Care, 2015, v. 38, n. 1, p. 132, doi. 10.2337/dc14-1958

By:

Lovshin, Julie A.;
Barnie, Annette;
DeAlmeida, Ariana;
Logan, Alexander;
Zinman, Bernard;
Drucker, Daniel J.

Publication type:

Article

Incretin-based therapy and the quest for sustained improvements in β-cell health.

Published in:

2011

By:

Drucker DJ;
Drucker, Daniel J

Publication type:

Editorial

Incretin-Based Therapy and the Quest for Sustained Improvements in β-Cell Health.

Published in:

2011

By:

DRUCKER, DANIEL J.

Publication type:

Editorial

DURATION-1: exenatide once weekly produces sustained glycemic control and weight loss over 52 weeks.

Published in:

2010

By:

Buse JB;
Drucker DJ;
Taylor KL;
Kim T;
Walsh B;
Hu H;
Wilhelm K;
Trautmann M;
Shen LZ;
Porter LE;
DURATION-1 Study Group;
Buse, John B;
Drucker, Daniel J;
Taylor, Kristin L;
Kim, Terri;
Walsh, Brandon;
Hu, Hao;
Wilhelm, Ken;
Trautmann, Michael;
Shen, Larry Z

Publication type:

journal article

DURATION-1. Exenatide Once Weekly Produces Sustained Glycemic Control and Weight Loss Over 52 Weeks.

Published in:

Diabetes Care, 2010, v. 33, n. 6, p. 1255, doi. 10.2337/dc09-1914

By:

Buse, John B.;
Drucker, Daniel J.;
Taylor, Kristin L.;
Kim, Terri;
Walsh, Brandon;
Hu, Hao;
Wilhelm, Ken;
Trautmann, Michael;
Shen, Larry Z.;
Porter, Lisa E.

Publication type:

Article

Incretin-Based Therapies for the Treatment of Type 2 Diabetes: Evaluation of the Risks and Benefits.

Published in:

Diabetes Care, 2010, v. 33, n. 2, p. 428, doi. 10.2337/dc09-1499

By:

Drucker, Daniel J.;
Sherman, Steven I.;
Gorelick, Fred S.;
Bergenstal, Richard M.;
Sherwin, Robert S.;
Buse, John B.

Publication type:

Article

Dipeptidyl Peptidase-4 Inhibition and the Treatment of Type 2 Diabetes.

Published in:

2007

By:

Drucker, Daniel J.

Publication type:

Editorial

Emerging Therapies Mimicking the Effects of Amylin and Glucagon-Like Peptide 1.

Published in:

Diabetes Care, 2006, v. 29, n. 2, p. 435, doi. 10.2337/diacare.29.02.06.dc05-1267

By:

Riddle, Matthew C.;
Drucker, Daniel J.

Publication type:

Article

Enhancing Incretin Action for the Treatment of Type 2 Diabetes.

Published in:

Diabetes Care, 2003, v. 26, n. 10, p. 2929, doi. 10.2337/diacare.26.10.2929

By:

Drucker, Daniel J.

Publication type:

Article

Unimolecular Dual Incretins Maximize Metabolic Benefits in Rodents, Monkeys, and Humans.

Published in:

Science Translational Medicine, 2013, v. 5, n. 209, p. 1, doi. 10.1126/scitranslmed.3007218

By:

Finan, Brian;
Tao Ma;
Ottaway, Nickki;
Müller, Timo D.;
Habegger, Kirk M.;
Heppner, Kristy M.;
Kirchner, Henriette;
Holland, Jenna;
Hembree, Jazzminn;
Raver, Christine;
Lockie, Sarah H.;
Smiley, David L.;
Gelfanov, Vasily;
Bin Yang;
Hofmann, Susanna;
Bruemmer, Dennis;
Drucker, Daniel J.;
Pfluger, Paul T.;
Perez-Tilve, Diego;
Gidda, Jaswant

Publication type:

Article

Endogenous Glucagon‐Like Peptide‐1 Receptor and Glucose‐Dependent Insulinotropic Polypeptide Receptor Signaling Inhibits Aeroallergen‐Induced Innate Airway Inflammation.

Published in:

Allergy, 2024, v. 79, n. 12, p. 3373, doi. 10.1111/all.16402

By:

Toki, Shinji;
Abney, Masako;
Zhang, Jian;
Rusznak, Mark;
Warren, Christian M.;
Newcomb, Dawn C.;
Cahill, Katherine N.;
Drucker, Daniel J.;
Niswender, Kevin D.;
Peebles, Ray Stokes

Publication type:

Article

Prolonged Gastrointestinal Transit in a Patient with a Glucagon-Like Peptide (GLP)-1- and -2-Producing Neuroendocrine Tumor.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2002, v. 87, n. 7, p. 3078, doi. 10.1210/jcem.87.7.8584

By:

BRUBAKER, PATRICIA L.;
DRUCKER, DANIEL J.;
ASA, SYLVIA L.;
SWALLOW, CAROL;
REDSTON, MARK;
GREENBERG, GORDON R.

Publication type:

Article

HOT TOPIC: Glucagon-Like Peptide 2.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 4, p. 1759, doi. 10.1210/jcem.86.4.7386

By:

DRUCKER, DANIEL J.

Publication type:

Article

Septal Glucagon-Like Peptide 1 Receptor Expression Determines Suppression of Cocaine-Induced Behavior.

Published in:

Neuropsychopharmacology, 2015, v. 40, n. 8, p. 1969, doi. 10.1038/npp.2015.47

By:

Harasta, Anne E;
Power, John M;
von Jonquieres, Georg;
Karl, Tim;
Drucker, Daniel J;
Housley, Gary D;
Schneider, Miriam;
Klugmann, Matthias

Publication type:

Article

Glucagon-like peptide-1 receptor is involved in learning and neuroprotection.

Published in:

Nature Medicine, 2003, v. 9, n. 9, p. 1173, doi. 10.1038/nm919

By:

During, Matthew J.;
Cao, Lei;
Zuzga, David S.;
Francis, Jeremy S.;
Fitzsimons, Helen L.;
Jiao, Xiangyang;
Bland, Ross J.;
Klugmann, Matthias;
Banks, William A.;
Drucker, Daniel J.;
Haile, Colin N.

Publication type:

Article

Evolving Concepts and Translational Relevance of Enteroendocrine Cell Biology.

Published in:

2016

By:

Drucker, Daniel J

Publication type:

journal article

The Safety of Incretin-Based Therapies—Review of the Scientific Evidence.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2011, v. 96, n. 7, p. 2027, doi. 10.1210/jc.2011-0599

By:

Drucker, Daniel J.;
Sherman, Steven I.;
Bergenstal, Richard M.;
Buse, John B.

Publication type:

Article

Tissue-Specific Role of Glycogen Synthase Kinase 3β in Glucose Homeostasis and Insulin Action.

Published in:

Molecular & Cellular Biology, 2008, v. 28, n. 20, p. 6314, doi. 10.1128/MCB.00763-08

By:

Patel, Satish;
Doble, Bradley W.;
MacAulay, Katrina;
Sinclair, Elaine M.;
Drucker, Daniel J.;
Woodgett, James R.

Publication type:

Article

The expanding incretin universe: from basic biology to clinical translation.

Published in:

Diabetologia, 2023, v. 66, n. 10, p. 1765, doi. 10.1007/s00125-023-05906-7

By:

Drucker, Daniel J.;
Holst, Jens J.

Publication type:

Article

Transforming type 1 diabetes: the next wave of innovation.

Published in:

Diabetologia, 2021, v. 64, n. 5, p. 1059, doi. 10.1007/s00125-021-05396-5

By:

Drucker, Daniel J.

Publication type:

Article

The Cushing syndrome induced by medroxyprogesterone acetate.

Published in:

1989

By:

Siminoski, Kerry;
Gross, Paul;
Drucker, Daniel J.;
Siminoski, K;
Goss, P;
Drucker, D J

Publication type:

journal article

Modulation of Taste Sensitivity by GLP-1 Signaling in Taste Buds.

Published in:

Annals of the New York Academy of Sciences, 2009, v. 1170, p. 98, doi. 10.1111/j.1749-6632.2009.03920.x

By:

Martin, Bronwen;
Dotson, Cedrick D.;
Shin, Yu‐Kyong;
Ji, Sunggoan;
Drucker, Daniel J.;
Maudsley, Stuart;
Munger, Steven D.

Publication type:

Article

GIPR Signaling in Immune Cells Maintains Metabolically Beneficial Type 2 Immune Responses in the White Fat From Obese Mice.

Published in:

Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.643144

By:

Efimova, Irina;
Steinberg, Inbar;
Zvibel, Isabel;
Neumann, Anat;
Mantelmacher, Dana Fernanda;
Drucker, Daniel J.;
Fishman, Sigal;
Varol, Chen

Publication type:

Article

GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02488-y

By:

Yusaku Iwasaki;
Mio Sendo;
Dezaki, Katsuya;
Masanori Nakata;
Chayon Goswami;
Ryohei Aoki;
Takeshi Arai;
Kumari, Parmila;
Toshihiko Yada;
Tohru Hira;
Hiroshi Hara;
Takehiro Sato;
Yuichiro Yamada;
Masaki Hayakawa;
Chiaki Masuda;
Takashi Okada;
Drucker, Daniel J.;
Masaaki Tokuda

Publication type:

Article

Sitagliptin Accelerates Endothelial Regeneration after Vascular Injury Independent from GLP1 Receptor Signaling.

Published in:

Stem Cells International, 2018, p. 1, doi. 10.1155/2018/5284963

By:

Remm, Friederike;
Kränkel, Nicolle;
Lener, Daniela;
Drucker, Daniel J.;
Sopper, Sieghart;
Brenner, Christoph

Publication type:

Article

Metabolic Disease Puts Up a Fight: Are diet and exercise helpful for the heart?

Published in:

Nature Medicine, 2013, v. 19, n. 10, p. 1216, doi. 10.1038/nm.3370

By:

Lovshin, Julie A;
Drucker, Daniel J

Publication type:

Article

GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure.

Published in:

Nature Medicine, 2013, v. 19, n. 5, p. 567, doi. 10.1038/nm.3128

By:

Kim, Minsuk;
Platt, Mathew J;
Shibasaki, Tadao;
Quaggin, Susan E;
Backx, Peter H;
Seino, Susumu;
Simpson, Jeremy A;
Drucker, Daniel J

Publication type:

Article

Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells.

Published in:

Nature Medicine, 2011, v. 17, n. 11, p. 1481, doi. 10.1038/nm.2513

By:

Ellingsgaard, Helga;
Hauselmann, Irina;
Schuler, Beat;
Habib, Abdella M;
Baggio, Laurie L;
Meier, Daniel T;
Eppler, Elisabeth;
Bouzakri, Karim;
Wueest, Stephan;
Muller, Yannick D;
Hansen, Ann Maria Kruse;
Reinecke, Manfred;
Konrad, Daniel;
Gassmann, Max;
Reimann, Frank;
Halban, Philippe A;
Gromada, Jesper;
Drucker, Daniel J;
Gribble, Fiona M;
Ehses, Jan A

Publication type:

Article

Normalization of obesity-associated insulin resistance through immunotherapy.

Published in:

Nature Medicine, 2009, v. 15, n. 8, p. 921, doi. 10.1038/nm.2001

By:

Winer, Shawn;
Chan, Yin;
Paltser, Geoffrey;
Truong, Dorothy;
Tsui, Hubert;
Bahrami, Jasmine;
Dorfman, Ruslan;
Wang, Yongqian;
Zielenski, Julian;
Mastronardi, Fabrizio;
Maezawa, Yuko;
Drucker, Daniel J.;
Engleman, Edgar;
Winer, Daniel;
Dosch, H.-Michael

Publication type:

Article

Glucagon-like peptide-1 is specifically involved in sweet taste transmission.

Published in:

FASEB Journal, 2015, v. 29, n. 6, p. 2268, doi. 10.1096/fj.14-265355

By:

Shingo Takai;
Keiko Yasumatsu;
Mayuko Inoue;
Shusuke Iwata;
Ryusuke Yoshida;
Noriatsu Shigemura;
Yuchio Yanagawa;
Drucker, Daniel J.;
Margolskee, Robert F.;
Yuzo Ninomiya

Publication type:

Article

Ciliary neurotrophic factor recruitment of glucagon-like peptide-1 mediates neurogenesis, allowing immortalization of adult murine hypothalamic neurons.

Published in:

FASEB Journal, 2009, v. 23, n. 12, p. 4256, doi. 10.1096/fj.09-133454

By:

Belsham, Denise D.;
Fick, Laura J.;
Dalvi, Prasad S.;
Centeno, Maria-Luisa;
Chalmers, Jennifer A.;
Lee, Paul K. P.;
Yangyang Wang;
Drucker, Daniel J.;
Koletar, Margaret M.

Publication type:

Article

β-Cell Inactivation of Unmasks Incretin Dependence of GPR119-Mediated Glucoregulation.

Published in:

2017

By:

Panaro, Brandon L.;
Flock, Grace B.;
Campbell, Jonathan E.;
Beaudry, Jacqueline L.;
Xiemin Cao;
Drucker, Daniel J.;
Cao, Xiemin

Publication type:

journal article