Works by Driscoll, Monica

Results: 46

The Core Apoptotic Executioner Proteins CED-3 and CED- 4 Promote Initiation of Neuronal Regeneration in Caenorhabditis elegans.

Published in:

PLoS Biology, 2012, v. 10, n. 5, p. 1, doi. 10.1371/journal.pbio.1001331

By:

Pinan-Lucarre, Berangere;
Gabel, Christopher V.;
Reina, Christopher P.;
Hulme, S. Elizabeth;
Shevkoplyas, Sergey S.;
Slone, R. Daniel;
Jian Xue;
Yujie Qiao;
Weisberg, Sarah;
Roodhouse, Kevin;
Lin Sun;
Whitesides, George M.;
Samuel, Aravinthan;
Driscoll, Monica

Publication type:

Article

The Biological Sciences Section Program at the 57th Annual Meeting of The Gerontological Society of America.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2005, v. 60, n. 11, p. 1359, doi. 10.1093/gerona/60.11.1359

By:

Jazwinski, S. Michal;
Warner, Huber R.;
Helfand, Stephen;
Driscoll, Monica;
Welsh, David A.;
Faulkner, John;
Barzilai, Nir;
Breitenbach, Michael;
McCarter, Roger;
Brow, W. Ted;
Greco, Nicholas;
Mountz, John;
Olshansky, S. Jay

Publication type:

Article

Age-Related Phasic Patterns of Mitochondrial Maintenance in Adult Caenorhabditis elegans Neurons.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 4, p. 1373, doi. 10.1523/JNEUROSCI.2799-15.2016

By:

Morsci, Natalia S.;
Hall, David H.;
Driscoll, Monica;
Sheng, Zu-Hang

Publication type:

Article

Q&A: Trash talk: disposal and remote degradation of neuronal garbage.

Published in:

BMC Biology, 2018, v. 16, p. 1, doi. 10.1186/s12915-018-0487-6

By:

Arnold, Meghan Lee;
Melentijevic, Ilija;
Smart, Anna Joelle;
Driscoll, Monica

Publication type:

Article

Single swim sessions in C. elegans induce key features of mammalian exercise.

Published in:

BMC Biology, 2017, p. 1, doi. 10.1186/s12915-017-0368-4

By:

Laranjeiro, Ricardo;
Harinath, Girish;
Burke, Daniel;
Braeckman, Bart P.;
Driscoll, Monica

Publication type:

Article

Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes.

Published in:

Nature Genetics, 2000, v. 24, n. 2, p. 180, doi. 10.1038/72850

By:

Tavernarakis, Nektarios;
Wang, Shi L.;
Dorovkov, Maxim;
Ryazanov, Alexey;
Driscoll, Monica

Publication type:

Article

Deletion of microRNA-80 Activates Dietary Restriction to Extend <i>C. elegans</i> Healthspan and Lifespan.

Published in:

PLoS Genetics, 2013, v. 9, n. 8, p. 1, doi. 10.1371/journal.pgen.1003737

By:

Vora, Mehul;
Shah, Mitalie;
Ostafi, Silvana;
Onken, Brian;
Xue, Jian;
Ni, Julie Zhouli;
Gu, Sam;
Driscoll, Monica

Publication type:

Article

A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans.

Published in:

PLoS Genetics, 2008, v. 4, n. 2, p. 1, doi. 10.1371/journal.pgen.0040024

By:

Hansen, Malene;
Chandra, Abha;
Mitic, Laura L.;
Onken, Brian;
Driscoll, Monica;
Kenyon, Cynthia

Publication type:

Article

Deficiency in RCAT-1 Function Causes Dopamine Metabolism Related Behavioral Disorders in Caenorhabditis elegans.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 4, p. 2393, doi. 10.3390/ijms23042393

By:

Jeong, Haelim;
Park, Jun Young;
Lee, Ji-Hyun;
Baik, Ja-Hyun;
Kim, Chae-Yeon;
Cho, Jin-Young;
Driscoll, Monica;
Paik, Young-Ki

Publication type:

Article

Neurite Sprouting and Synapse Deterioration in the Aging Caenorhabditis elegans Nervous System.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 26, p. 8778, doi. 10.1523/JNEUROSCI.1494-11.2012

By:

Toth, Marton Lorant;
Melentijevic, Ilija;
Shah, Leena;
Bhatia, Aatish;
Lu, Kevin;
Talwar, Amish;
Naji, Haaris;
Ibanez-Ventoso, Carolina;
Ghose, Piya;
Jevince, Angela;
Jian Xue;
Herndon, Laura A.;
Bhanot, Gyan;
Rongo, Chris;
Hall, David H.;
Driscoll, Monica

Publication type:

Article

FOXO3a Is Broadly Neuroprotective In Vitro and In Vivo against Insults Implicated in Motor Neuron Diseases.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 25, p. 8236, doi. 10.1523/JNEUROSCI.1805-09.2009

By:

Mojsilovic-Petrovic, Jelena;
Nedelsky, Natalia;
Boccitto, Marco;
Mano, Itzhak;
Georgiades, Savvas N.;
Weiguo Zhou;
Yuhong Liu;
Neve, Rachael L.;
Taylor, J. Paul;
Driscoll, Monica;
Clardy, Jon;
Merry, Diane;
Kalb, Robert G.

Publication type:

Article

Dying for a cause: invertebrate genetics takes on human neurodegeneration.

Published in:

2003

By:

Driscoll, Monica;
Gerstbrein, Beate

Publication type:

journal article

Modulated microRNA expression during adult lifespan in Caenorhabditis elegans.

Published in:

Aging Cell, 2006, v. 5, n. 3, p. 235, doi. 10.1111/j.1474-9726.2006.00210.x

By:

Ibáñez-Ventoso, Carolina;
Maocheng Yang;
Suzhen Guo;
Robins, Harlan;
Padgett, Richard W.;
Driscoll, Monica

Publication type:

Article

In vivospectrofluorimetry reveals endogenous biomarkers that report healthspan and dietary restriction inCaenorhabditis elegans.

Published in:

Aging Cell, 2005, v. 4, n. 3, p. 127, doi. 10.1111/j.1474-9726.2005.00153.x

By:

Gerstbrein, Beate;
Stamatas, Georgios;
Kollias, Nikiforos;
Driscoll, Monica

Publication type:

Article

Caenorhabditis Elegans Degenerins and Vertebrate Enac Ion Channels Contain an Extracellular Domain Related to Venom Neurotoxins.

Published in:

Journal of Neurogenetics, 2000, v. 13, n. 4, p. 257, doi. 10.3109/01677060009084497

By:

Tavernarakis, Nektarios;
Driscoll, Monica

Publication type:

Article

Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.95443

By:

Guoqiang Wang;
Guasp, Ryan J.;
Salam, Sangeena;
Chuang, Edward;
Morera, Andrés;
Smart, Anna J.;
Jimenez, David;
Shekhar, Sahana;
Friedman, Emily;
Melentijevic, Ilija;
Ken C. Nguyen;
Hall, David H.;
Grant, Barth D.;
Driscoll, Monica

Publication type:

Article

Pluronic gel-based burrowing assay for rapid assessment of neuromuscular health in C. elegans.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-51608-9

By:

Lesanpezeshki, Leila;
Hewitt, Jennifer E.;
Laranjeiro, Ricardo;
Antebi, Adam;
Driscoll, Monica;
Szewczyk, Nathaniel J.;
Blawzdziewicz, Jerzy;
Lacerda, Carla M. R.;
Vanapalli, Siva A.

Publication type:

Article

CED-4 CARD domain residues can modulate non-apoptotic neuronal regeneration functions independently from apoptosis.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-49633-9

By:

Wang, Guoqiang;
Sun, Lin;
Reina, Christopher P.;
Song, Isaac;
Gabel, Christopher V.;
Driscoll, Monica

Publication type:

Article

Specific roles for DEG/ENaC and TRP channels in touch and thermosensation in C. elegans nociceptors.

Published in:

Nature Neuroscience, 2010, v. 13, n. 7, p. 861, doi. 10.1038/nn.2581

By:

Chatzigeorgiou, Marios;
Sungjae Yoo;
Watson, Joseph D.;
Wei-Hsiang Lee;
Spencer, W. Clay;
Kindt, Katie S.;
Sun Wook Hwang;
Miller III, David M.;
Treinin, Millet;
Driscoll, Monica;
Schafer, William R.

Publication type:

Article

DEG/ENaC channels: a touchy superfamily that watches its salt.

Published in:

BioEssays, 1999, v. 21, n. 7, p. 568, doi. 10.1002/(SICI)1521-1878(199907)21:7<568::AID-BIES5>3.0.CO;2-L

By:

Mano, Itzhak;
Driscoll, Monica

Publication type:

Article

A transmembrane domain of the putative channel subunit MEC-4 influences mechanotransduction and...

Published in:

Nature, 1994, v. 367, n. 6462, p. 470, doi. 10.1038/367470a0

By:

Hong, Kyonsoo;
Driscoll, Monica

Publication type:

Article

NIA Caenorhabditis Intervention Testing Program: identification of robust and reproducible pharmacological interventions that promote longevity across experimentally accessible, genetically diverse populations.

Published in:

GeroScience, 2025, v. 47, n. 3, p. 2791, doi. 10.1007/s11357-025-01627-4

By:

Driscoll, Monica;
Sedore, Christine A.;
Onken, Brian;
Coleman-Hulbert, Anna L.;
Johnson, Erik;
Phillips, Patrick C.;
Lithgow, Gordon

Publication type:

Article

TOR-mediated regulation of metabolism in aging.

Published in:

Aging Cell, 2017, v. 16, n. 6, p. 1219, doi. 10.1111/acel.12689

By:

Antikainen, Henri;
Driscoll, Monica;
Haspel, Gal;
Dobrowolski, Radek

Publication type:

Article

Using measures of single-cell physiology and physiological state to understand organismic aging.

Published in:

Aging Cell, 2016, v. 15, n. 1, p. 4, doi. 10.1111/acel.12424

By:

Mendenhall, Alexander;
Driscoll, Monica;
Brent, Roger

Publication type:

Article

Novel EGF pathway regulators modulate C. elegans healthspan and lifespan via EGF receptor, PLC-γ, and IP3R activation.

Published in:

Aging Cell, 2010, v. 9, n. 4, p. 490, doi. 10.1111/j.1474-9726.2010.00575.x

By:

Hiroaki Iwasa;
Simon Yu;
Jian Xue;
Driscoll, Monica

Publication type:

Article

A lysine-rich motif in the phosphatidylserine receptor PSR-1 mediates recognition and removal of apoptotic cells.

Published in:

Nature Communications, 2015, v. 6, n. 1, p. 5717, doi. 10.1038/ncomms6717

By:

Yang, Hengwen;
Chen, Yu-Zen;
Zhang, Yi;
Wang, Xiaohui;
Zhao, Xiang;
Godfroy, James I.;
Liang, Qian;
Zhang, Man;
Zhang, Tianying;
Yuan, Quan;
Ann Royal, Mary;
Driscoll, Monica;
Xia, Ning-Shao;
Yin, Hang;
Xue, Ding

Publication type:

Article

MOLECULAR MECHANISMS OF NECROTIC-LKE CELL DEATH IN C. elegans.

Published in:

1999

By:

Driscoll, Monica

Publication type:

Abstract

CeleST: Computer Vision Software for Quantitative Analysis of <i>C. elegans</i> Swim Behavior Reveals Novel Features of Locomotion.

Published in:

PLoS Computational Biology, 2014, v. 10, n. 7, p. 1, doi. 10.1371/journal.pcbi.1003702

By:

Restif, Christophe;
Ibáñez-Ventoso, Carolina;
Vora, Mehul M.;
Guo, Suzhen;
Metaxas, Dimitris;
Driscoll, Monica

Publication type:

Article

Degenerins.

Published in:

Annals of the New York Academy of Sciences, 2001, v. 940, n. 1, p. 28, doi. 10.1111/j.1749-6632.2001.tb03664.x

By:

TAVERNARAKIS, NEKTARIOS;
DRISCOLL, MONICA

Publication type:

Article

Insulin signaling in the aging of healthy and proteotoxically stressed mechanosensory neurons.

Published in:

Frontiers in Genetics, 2014, v. 5, p. 1, doi. 10.3389/fgene.2014.00212

By:

Scerbak, Courtney;
Vayndorf, Elena M.;
Parker, J. Alex;
Neri, Christian;
Driscoll, Monica;
Taylor, Barbara E.

Publication type:

Article

Insulin Signaling in the Aging of Healthy and Proteotoxically Stressed Mechanosensory Neurons.

Published in:

Frontiers in Genetics, 2014, v. 5, p. 1, doi. 10.3389/fgene.2014.00212

By:

Scerbak, Courtney;
Vayndorf, Elena M.;
Parker, J. Alex;
Neri, Christian;
Driscoll, Monica;
Taylor, Barbara E.

Publication type:

Article

A glial DEG/ENaC channel functions with neuronal channel DEG-1 to mediate specific sensory functions in C. elegans.

Published in:

2008

By:

Ying Wang;
Apicella Jr., Alfonso;
Sun-Kyung Lee;
Ezcurra, Marina;
Slone, Robert D.;
Goldmit, Maya;
Schafer, William R.;
Shaham, Shai;
Driscoll, Monica;
Bianchi, Laura

Publication type:

Correction Notice

A glial DEG/ENaC channel functions with neuronal channel DEG-1 to mediate specific sensory functions in C. elegans.

Published in:

EMBO Journal, 2008, v. 27, n. 18, p. 2388, doi. 10.1038/emboj.2008.161

By:

Ying Wang;
Apicella, Alfonso;
Sun-Kyung Lee;
Ezcurra, Marina;
Slone, Robert D.;
Goldmit, Maya;
Schafer, William R.;
Shaham, Shai;
Driscoll, Monica;
Bianchi, Laura

Publication type:

Article

Caenorhabditis elegans glutamate transporter deletion induces AMPA-receptor/adenylyl cyclase 9-dependent excitotoxicity.

Published in:

Journal of Neurochemistry, 2009, v. 108, n. 6, p. 1373, doi. 10.1111/j.1471-4159.2008.05804.x

By:

Mano, Itzhak;
Driscoll, Monica

Publication type:

Article

Gluconeogenesis and PEPCK are critical components of healthy aging and dietary restriction life extension.

Published in:

PLoS Genetics, 2020, v. 16, n. 8, p. 1, doi. 10.1371/journal.pgen.1008982

By:

Onken, Brian;
Kalinava, Natallia;
Driscoll, Monica

Publication type:

Article

Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans.

Published in:

Nature, 2002, v. 419, n. 6910, p. 939, doi. 10.1038/nature01108

By:

Syntichaki, Popi;
Xu, Keli;
Driscoll, Monica;
Tavernarakis, Nektarios

Publication type:

Article

Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans.

Published in:

Nature, 2002, v. 419, n. 6909, p. 808, doi. 10.1038/nature01135

By:

Herndon, Laura A.;
Schmeissner, Peter J.;
Dudaronek, Justyna M.;
Brown, Paula A.;
Listner, Kristin M.;
Sakano, Yuko;
Paupard, Marie C.;
Hall, David H.;
Driscoll, Monica

Publication type:

Article

Large vesicle extrusions from C. elegans neurons are consumed and stimulated by glial-like phagocytosis activity of the neighboring cell.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.82227

By:

Yu Wang;
Arnold, Meghan Lee;
Smart, Anna Joelle;
Guoqiang Wang;
Androwski, Rebecca J.;
Morera, Andres;
Nguyen, Ken C. Q.;
Schweinsberg, Peter J.;
Ge Bai;
Cooper, Jason;
Hall, David H.;
Driscoll, Monica;
Grant, Barth D.

Publication type:

Article

NemaLife chip: a micropillar-based microfluidic culture device optimized for aging studies in crawling C. elegans.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-73002-6

By:

Rahman, Mizanur;
Edwards, Hunter;
Birze, Nikolajs;
Gabrilska, Rebecca;
Rumbaugh, Kendra P.;
Blawzdziewicz, Jerzy;
Szewczyk, Nathaniel J.;
Driscoll, Monica;
Vanapalli, Siva A.

Publication type:

Article

A common set of engulfment genes mediates removal of both apoptotic and necrotic cell corpses in C. elegans.

Published in:

Nature Cell Biology, 2000, v. 2, n. 12, p. 931, doi. 10.1038/35046585

By:

Chung, Sambath;
Gumienny, Tina L.;
Hengartner, Michael O.;
Driscoll, Monica

Publication type:

Article

The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: implications for necrosis initiation.

Published in:

Nature Neuroscience, 2004, v. 7, n. 12, p. 1337, doi. 10.1038/nn1347

By:

Bianchi, Laura;
Gerstbrein, Beate;
Frøkjær-Jensen, Christian;
Royal, Dewey C.;
Mukherjee, Gargi;
Royal, Mary Anne;
Xue, Jian;
Schafer, William R.;
Driscoll, Monica

Publication type:

Article

Closing in on a mammalian touch receptor.

Published in:

Nature Neuroscience, 2000, v. 3, n. 12, p. 1232, doi. 10.1038/81746

By:

Driscoll, Monica;
Tavernarakis, Nektarios

Publication type:

Article

Metformin Induces a Dietary Restriction-Like State and the Oxidative Stress Response to Extend C. elegans Healthspan via AMPK, LKB1, and SKN-1.

Published in:

PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008758

By:

Onken, Brian;
Driscoll, Monica

Publication type:

Article

Sequence Relationships among C. elegans, D. melanogaster and Human microRNAs Highlight the Extensive Conservation of microRNAs in Biology.

Published in:

PLoS ONE, 2008, v. 3, n. 7, p. 1, doi. 10.1371/journal.pone.0002818

By:

Ibáñez-Ventoso, Carolina;
Vora, Mehul;
Driscoll, Monica

Publication type:

Article

Cell Death in C. elegans: Molecular insights into Mechanisms Conserved Between Nematodes and Mammals.

Published in:

Brain Pathology, 1996, v. 6, n. 4, p. 411, doi. 10.1111/j.1750-3639.1996.tb00873.x

By:

Driscoll, Monica

Publication type:

Article

The longevity-promoting factor, TCER-1, widely represses stress resistance and innate immunity.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10759-z

By:

Amrit, Francis R. G.;
Naim, Nikki;
Ratnappan, Ramesh;
Loose, Julia;
Mason, Carter;
Steenberge, Laura;
McClendon, Brooke T.;
Wang, Guoqiang;
Driscoll, Monica;
Yanowitz, Judith L.;
Ghazi, Arjumand

Publication type:

Article