Works by Drijfhout, Jan W.

Results: 54
    1

    Controlled Release of LL-37-Derived Synthetic Antimicrobial and Anti-Biofilm Peptides SAAP-145 and SAAP-276 Prevents Experimental Biomaterial-Associated Staphylococcus aureus Infection.

    Published in:
    Advanced Functional Materials, 2017, v. 27, n. 20, p. n/a, doi. 10.1002/adfm.201606623
    By:
    • Riool, Martijn;
    • de Breij, Anna;
    • de Boer, Leonie;
    • Kwakman, Paulus H. S.;
    • Cordfunke, Robert A.;
    • Cohen, Or;
    • Malanovic, Nermina;
    • Emanuel, Noam;
    • Lohner, Karl;
    • Drijfhout, Jan W.;
    • Nibbering, Peter H.;
    • Zaat, Sebastian A. J.
    Publication type:
    Article
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    Long lasting p53-specific T cell memory responses in the absence of anti-p53 antibodies in patients with resected primary colorectal cancer.

    Published in:
    European Journal of Immunology, 2001, v. 31, n. 1, p. 146, doi. 10.1002/1521-4141(200101)31:1<146::AID-IMMU146>3.0.CO;2-T
    By:
    • van der Burg, Sjoerd H.;
    • de Cock, Karin;
    • Menon, Anand G.;
    • Franken, Kees L. M. C;
    • Palmen, Mary;
    • Redeker, Anke;
    • Drijfhout, Jan W.;
    • Kuppen, Peter J. K.;
    • van de Velde, Cornelis J. H.;
    • Erdile, Lorne;
    • Tollenaar, Rob A. E. M.;
    • Melief, Cornelis J. M.;
    • Offringa, Rienk
    Publication type:
    Article
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    An HLA-A*11:01-Binding Neoantigen from Mutated NPM1 as Target for TCR Gene Therapy in AML.

    Published in:
    Cancers, 2021, v. 13, n. 21, p. 5390, doi. 10.3390/cancers13215390
    By:
    • van der Lee, Dyantha I.;
    • Koutsoumpli, Georgia;
    • Reijmers, Rogier M.;
    • Honders, Willy;
    • de Jong, Rob C. M.;
    • Remst, Dennis F. G.;
    • Wachsmann, Tassilo L. A.;
    • Hagedoorn, Renate S.;
    • Franken, Kees L. M. C.;
    • Kester, Michel G. D.;
    • Harber, Karl J.;
    • Roelofsen, Lisanne M.;
    • Schouten, Annemiek M.;
    • Mulder, Arend;
    • Drijfhout, Jan W.;
    • Veelken, Hendrik;
    • van Veelen, Peter A.;
    • Heemskerk, Mirjam H. M.;
    • Falkenburg, Frederik;
    • Griffioen, Marieke
    Publication type:
    Article
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    T-cell receptor recognition of HLA-DQ2-gliadin complexes associated with celiac disease.

    Published in:
    Nature Structural & Molecular Biology, 2014, v. 21, n. 5, p. 480, doi. 10.1038/nsmb.2817
    By:
    • Petersen, Jan;
    • Montserrat, Veronica;
    • Mujico, Jorge R;
    • Loh, Khai Lee;
    • Beringer, Dennis X;
    • van Lummel, Menno;
    • Thompson, Allan;
    • Mearin, M Luisa;
    • Schweizer, Joachim;
    • Kooy-Winkelaar, Yvonne;
    • van Bergen, Jeroen;
    • Drijfhout, Jan W;
    • Kan, Wan-Ting;
    • La Gruta, Nicole L;
    • Anderson, Robert P;
    • Reid, Hugh H;
    • Koning, Frits;
    • Rossjohn, Jamie
    Publication type:
    Article
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    Cd8 T-cell recognition of human 5T4 oncofetal antigen.

    Published in:
    International Journal of Cancer, 2006, v. 119, n. 7, p. 1638, doi. 10.1002/ijc.22018
    By:
    • Smyth, Lucy JC;
    • Elkord, Eyad;
    • Taher, Taher E.I.;
    • Jiang, Hui-Rong;
    • Burt, Deborah J.;
    • Clayton, Alison;
    • van Veelen, Peter A.;
    • de Ru, Arnoud;
    • Ossendorp, Ferry;
    • Melief, Cornelis J. M.;
    • Drijfhout, Jan W.;
    • Dermime, Said;
    • Hawkins, Robert E.;
    • Stern, Peter L.
    Publication type:
    Article
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    Cross-reactivity of IgM anti-modified protein antibodies in rheumatoid arthritis despite limited mutational load.

    Published in:
    Arthritis Research & Therapy, 2021, v. 23, n. 1, p. 1, doi. 10.1186/s13075-021-02609-5
    By:
    • Reijm, Sanne;
    • Kissel, Theresa;
    • Stoeken-Rijsbergen, Gerrie;
    • Slot, Linda M.;
    • Wortel, Corrie M.;
    • van Dooren, Hugo J.;
    • Levarht, Nivine E. W.;
    • Kampstra, Arieke S. B.;
    • Derksen, Veerle F. A. M.;
    • Heer, Pleuni Ooijevaar-de;
    • Bang, Holger;
    • Drijfhout, Jan W.;
    • Trouw, Leendert A.;
    • Huizinga, Tom W. J.;
    • Rispens, Theo;
    • Scherer, Hans U.;
    • Toes, René E. M.
    Publication type:
    Article
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    The antimicrobial peptide SAAP-148 combats drug-resistant bacteria and biofilms.

    Published in:
    Science Translational Medicine, 2018, v. 10, n. 423, p. 1, doi. 10.1126/scitranslmed.aan4044
    By:
    • de Breij, Anna;
    • Riool, Martijn;
    • Cordfunke, Robert A.;
    • Malanovic, Nermina;
    • de Boer, Leonie;
    • Koning, Roman I.;
    • Ravensbergen, Elisabeth;
    • Franken, Marnix;
    • van der Heijde, Tobias;
    • Boekema, Bouke K.;
    • Kwakman, Paulus H. S.;
    • Kamp, Niels;
    • El Ghalbzouri, Abdelouahab;
    • Lohner, Karl;
    • Zaat, Sebastian A. J.;
    • Drijfhout, Jan W.;
    • Nibbering, Peter H.
    Publication type:
    Article
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    Addition of interferon-α to the p53-SLP® vaccine results in increased production of interferon-γ in vaccinated colorectal cancer patients: A phase I/II clinical trial.

    Published in:
    International Journal of Cancer, 2013, v. 132, n. 7, p. 1581, doi. 10.1002/ijc.27819
    By:
    • Zeestraten, Eliane C.M.;
    • Speetjens, Frank M.;
    • Welters, Marij J.P.;
    • Saadatmand, Sepideh;
    • Stynenbosch, Linda F.M.;
    • Jongen, Rogier;
    • Kapiteijn, Ellen;
    • Gelderblom, Hans;
    • Nijman, Hans W.;
    • Valentijn, A. Rob P.M.;
    • Oostendorp, Jaap;
    • Fathers, Lorraine M.;
    • Drijfhout, Jan W.;
    • van de Velde, Cornelis J.H.;
    • Kuppen, Peter J.K.;
    • van der Burg, Sjoerd H.;
    • Melief, Cornelis J.M.
    Publication type:
    Article
    33

    Potentiation of a p53-SLP vaccine by cyclophosphamide in ovarian cancer: A single-arm phase II study.

    Published in:
    International Journal of Cancer, 2012, v. 131, n. 5, p. E670, doi. 10.1002/ijc.27388
    By:
    • Vermeij, Renee;
    • Leffers, Ninke;
    • Hoogeboom, Baukje-Nynke;
    • Hamming, Ineke L.E.;
    • Wolf, Rinze;
    • Reyners, Anna K.L.;
    • Molmans, Barbara H.W.;
    • Hollema, Harry;
    • Bart, Joost;
    • Drijfhout, Jan W.;
    • Oostendorp, Jaap;
    • van der Zee, Ate G.J.;
    • Melief, Cornelis J.;
    • van der Burg, Sjoerd H.;
    • Daemen, Toos;
    • Nijman, Hans W.
    Publication type:
    Article
    34

    Immunization with a P53 synthetic long peptide vaccine induces P53-specific immune responses in ovarian cancer patients, a phase II trial.

    Published in:
    International Journal of Cancer, 2009, v. 125, n. 9, p. 2104, doi. 10.1002/ijc.24597
    By:
    • Leffers, Ninke;
    • Lambeck, Annechien J.A.;
    • Gooden, Marloes J.M.;
    • Hoogeboom, Baukje-Nynke;
    • Wolf, Rinze;
    • Hamming, Ineke E.;
    • Hepkema, Bouke G.;
    • Willemse, Pax H.B.;
    • Molmans, Barbara H.W.;
    • Hollema, Harry;
    • Drijfhout, Jan W.;
    • Sluiter, Willem J.;
    • Valentijn, A. Rob P.M.;
    • Fathers, Loraine M.;
    • Oostendorp, Jaap;
    • van der Zee, Ate G.J.;
    • Melief, Cornelis J.;
    • van der Burg, Sjoerd H.;
    • Daemen, Toos;
    • Nijman, Hans W.
    Publication type:
    Article
    35

    Skin reactions to human papillomavirus (HPV) 16 specific antigens intradermally injected in healthy subjects and patients with cervical neoplasia.

    Published in:
    International Journal of Cancer, 2008, v. 123, n. 1, p. 146, doi. 10.1002/ijc.23502
    By:
    • van den Hende, Muriel;
    • van Poelgeest, Mariëtte I.E.;
    • van der Hulst, Jeanette M.;
    • de Jong, Joan;
    • Drijfhout, Jan W.;
    • Fleuren, Gert Jan;
    • Valentijn, A. Rob P.M.;
    • Wafelman, Amon R.;
    • Slappendel, Gijs M.;
    • Melief, Cornelis J.M.;
    • Offringa, Rienk;
    • van der Burg, Sjoerd H.;
    • Kenter, Gemma G.
    Publication type:
    Article
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    Immunogenic stress and death of cancer cells: Contribution of antigenicity vs adjuvanticity to immunosurveillance.

    Published in:
    Immunological Reviews, 2017, v. 280, n. 1, p. 165, doi. 10.1111/imr.12582
    By:
    • Bloy, Norma;
    • Garcia, Pauline;
    • Laumont, Céline M.;
    • Pitt, Jonathan M.;
    • Sistigu, Antonella;
    • Stoll, Gautier;
    • Yamazaki, Takahiro;
    • Bonneil, Eric;
    • Buqué, Aitziber;
    • Humeau, Juliette;
    • Drijfhout, Jan W.;
    • Meurice, Guillaume;
    • Walter, Steffen;
    • Fritsche, Jens;
    • Weinschenk, Toni;
    • Rammensee, Hans-Georg;
    • Melief, Cornelis;
    • Thibault, Pierre;
    • Perreault, Claude;
    • Pol, Jonathan
    Publication type:
    Article
    39

    A Broad-Spectrum Antiviral Peptide Blocks Infection of Viruses by Binding to Phosphatidylserine in the Viral Envelope.

    Published in:
    Cells (2073-4409), 2020, v. 9, n. 9, p. 1989, doi. 10.3390/cells9091989
    By:
    • Luteijn, Rutger D.;
    • Praest, Patrique;
    • Thiele, Frank;
    • Sadasivam, Saravanan Manikam;
    • Singethan, Katrin;
    • Drijfhout, Jan W.;
    • Bach, Christian;
    • de Boer, Steffen Matthijn;
    • Lebbink, Robert J.;
    • Tao, Sha;
    • Helfer, Markus;
    • Bach, Nina C.;
    • Protzer, Ulrike;
    • Costa, Ana I.;
    • Killian, J. Antoinette;
    • Drexler, Ingo;
    • Wiertz, Emmanuel J. H. J.
    Publication type:
    Article
    40

    Ototopical drops containing a novel antibacterial synthetic peptide: Safety and efficacy in adults with chronic suppurative otitis media.

    Published in:
    PLoS ONE, 2020, v. 15, n. 4, p. 1, doi. 10.1371/journal.pone.0231573
    By:
    • Peek, Nanno F. A. W.;
    • Nell, Marja J.;
    • Brand, Ronald;
    • Jansen-Werkhoven, Thekla;
    • van Hoogdalem, Ewoud J.;
    • Verrijk, Ruud;
    • Vonk, Marcel J.;
    • Wafelman, Amon R.;
    • Valentijn, A. Rob P. M.;
    • Frijns, Johan H. M.;
    • Hiemstra, Pieter S.;
    • Drijfhout, Jan W.;
    • Nibbering, Peter H.;
    • Grote, Jan J.
    Publication type:
    Article
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    Skin-Depigmenting Agent Monobenzone Induces Potent T-Cell Autoimmunity toward Pigmented Cells by Tyrosinase Haptenation and Melanosome Autophagy.

    Published in:
    Journal of Investigative Dermatology, 2011, v. 131, n. 6, p. 1240, doi. 10.1038/jid.2011.16
    By:
    • van den Boorn, Jasper G.;
    • Picavet, Daisy I.;
    • van Swieten, Paul F.;
    • van Veen, Henk A.;
    • Konijnenberg, Debby;
    • van Veelen, Peter A.;
    • van Capel, Toni;
    • Jong, Esther C. de;
    • Reits, Eric A.;
    • Drijfhout, Jan W.;
    • Bos, Jan D.;
    • Melief, Cornelis J. M.;
    • Luiten, Rosalie M.
    Publication type:
    Article
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    Structural basis for the killing of human beta cells by CD8<sup>+</sup> T cells in type 1 diabetes.

    Published in:
    Nature Immunology, 2012, v. 13, n. 3, p. 283, doi. 10.1038/ni.2206
    By:
    • Bulek, Anna M;
    • Cole, David K;
    • Skowera, Ania;
    • Dolton, Garry;
    • Gras, Stephanie;
    • Madura, Florian;
    • Fuller, Anna;
    • Miles, John J;
    • Gostick, Emma;
    • Price, David A;
    • Drijfhout, Jan W;
    • Knight, Robin R;
    • Huang, Guo C;
    • Lissin, Nikolai;
    • Molloy, Peter E;
    • Wooldridge, Linda;
    • Jakobsen, Bent K;
    • Rossjohn, Jamie;
    • Peakman, Mark;
    • Rizkallah, Pierre J
    Publication type:
    Article
    45
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    Dendritic cells process synthetic long peptides better than whole protein, improving antigen presentation and T-cell activation.

    Published in:
    European Journal of Immunology, 2013, v. 43, n. 10, p. 2554, doi. 10.1002/eji.201343324
    By:
    • Rosalia, Rodney A.;
    • Quakkelaar, Esther D.;
    • Redeker, Anke;
    • Khan, Selina;
    • Camps, Marcel;
    • Drijfhout, Jan W.;
    • Silva, Ana Luisa;
    • Jiskoot, Wim;
    • Hall, Thorbald;
    • Veelen, Peter A.;
    • Janssen, George;
    • Franken, Kees;
    • Cruz, Luis J.;
    • Tromp, Angelino;
    • Oostendorp, Jaap;
    • Burg, Sjoerd H.;
    • Ossendorp, Ferry;
    • Melief, Cornelis J. M.
    Publication type:
    Article
    47
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    Long peptides induce polyfunctional T cells against conserved regions of HIV-1 with superior breadth to single-gene vaccines in macaques.

    Published in:
    European Journal of Immunology, 2010, v. 40, n. 7, p. 1973, doi. 10.1002/eji.201040344
    By:
    • Rosario, Maximillian;
    • Bridgeman, Anne;
    • Quakkelaar, Esther D.;
    • Quigley, Maire F.;
    • Hill, Brenna J.;
    • Knudsen, Maria L.;
    • Ammendola, Virginia;
    • Ljungberg, Karl;
    • Borthwick, Nicola;
    • Im, Eung-Jun;
    • McMichael, Andrew J.;
    • Drijfhout, Jan W.;
    • Greenaway, Hui Yee;
    • Venturi, Vanessa;
    • Douek, Daniel C.;
    • Colloca, Stefano;
    • Liljeström, Peter;
    • Nicosia, Alfredo;
    • Price, David A.;
    • Melief, Cornelis J. M.
    Publication type:
    Article
    50

    Evaluation of Immunological Cross-Reactivity between Clade A9 High-Risk Human Papillomavirus Types on the Basis of E6-Specific CD4+ Memory T Cell Responses.

    Published in:
    Journal of Infectious Diseases, 2010, v. 202, n. 8, p. 1200, doi. 10.1086/656367
    By:
    • van den Hende, Muriel;
    • Redeker, Anke;
    • Kwappenberg, Kitty M. C.;
    • Franken, Kees L. M. C.;
    • Drijfhout, Jan W.;
    • Oostendorp, Jaap;
    • Valentijn, A. Rob P. M.;
    • Fathers, Loraine M.;
    • Welters, Marij J. P.;
    • Melief, Cornelis J. M.;
    • Kenter, Gemma G.;
    • van der Burg, Sjoerd H.;
    • Offringa, Rienk
    Publication type:
    Article