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Lipidomic signatures for APOE genotypes provides new insights about mechanisms of resilience in Alzheimer’s disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056703
By:
- Wang, Tingting;
- Huynh, Kevin;
- Giles, Corey;
- Lim, Wei Ling Florence;
- Duong, Thy;
- Mellett, Natalie A.;
- Smith, Alexander;
- Olshansky, Gavriel;
- Drew, Brian G.;
- Cadby, Gemma;
- Melton, Phillip E.;
- Hung, Joseph;
- Beilby, John;
- Watts, Gerald F.;
- Chatterjee, Pratishtha;
- Martins, Ian;
- Laws, Simon M.;
- Bush, Ashley I.;
- Rowe, Christopher C.;
- Villemagne, Victor L.
Publication type:
Article
Identification of concordant plasma lipid signatures in Alzheimer's disease: Validation between two independent studies of Alzheimer's disease: Biomarkers (non‐neuroimaging): Novel biomarkers.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042275
By:
- Huynh, Kevin;
- Lim, Wei Ling Florence;
- Giles, Corey;
- Jayawardana, Kaushala S;
- Salim, Agus;
- Mellett, Natalie A;
- Smith, Alexander;
- Olshansky, Gavriel;
- Drew, Brian G;
- Chatterjee, Pratishtha;
- Martins, Ian;
- Laws, Simon M;
- Bush, Ashley I;
- Rowe, Christopher C;
- Villemagne, Victor LL;
- Ames, David;
- Masters, Colin L;
- Arnold, Matthias;
- Nho, Kwangsik;
- Saykin, Andrew J.
Publication type:
Article
Deletion of the muscle enriched lncRNA Oip5os1 induces atrial dysfunction in male mice with diabetes.
Published in:
Physiological Reports, 2023, v. 11, n. 23, p. 1, doi. 10.14814/phy2.15869
By:
- Zhuang, Aowen;
- Tan, Yanie;
- Liu, Yingying;
- Yang, Christine;
- Kiriazis, Helen;
- Grigolon, Kyah;
- Walker, Shannen;
- Bond, Simon T.;
- McMullen, Julie R.;
- Calkin, Anna C.;
- Drew, Brian G.
Publication type:
Article
ACAD10 is not required for metformin's metabolic actions or for maintenance of whole‐body metabolism in C57BL/6J mice.
Published in:
Diabetes, Obesity & Metabolism, 2024, v. 26, n. 5, p. 1731, doi. 10.1111/dom.15484
By:
- Yew, Michael J.;
- Heywood, Sarah E.;
- Ng, Joe;
- West, Olivia M.;
- Pal, Martin;
- Kueh, Andrew;
- Lancaster, Graeme I.;
- Myers, Stephen;
- Yang, Christine;
- Liu, Yingying;
- Reibe, Saskia;
- Mellett, Natalie A.;
- Meikle, Peter J.;
- Febbraio, Mark A.;
- Greening, David W.;
- Drew, Brian G.;
- Henstridge, Darren C.
Publication type:
Article
Skeletal muscle‐specific overexpression of heat shock protein 72 improves skeletal muscle insulin‐stimulated glucose uptake but does not alter whole body metabolism.
Published in:
Diabetes, Obesity & Metabolism, 2018, v. 20, n. 8, p. 1928, doi. 10.1111/dom.13319
By:
- Marshall, Jessica P. S.;
- Estevez, Emma;
- Kammoun, Helene L.;
- King, Emily J.;
- Bruce, Clinton R.;
- Drew, Brian G.;
- Qian, Hongwei;
- Iliades, Peter;
- Gregorevic, Paul;
- Febbraio, Mark A.;
- Henstridge, Darren C.
Publication type:
Article
Skeletal Muscle Insulin Resistance Associated with Cholesterol-Induced Activation of Macrophages Is Prevented by High Density Lipoprotein.
Published in:
PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056601
By:
- Carey, Andrew L.;
- Siebel, Andrew L.;
- Reddy-Luthmoodoo, Medini;
- Natoli, Alaina K.;
- D’Souza, Wilissa;
- Meikle, Peter J.;
- Sviridov, Dmitri;
- Drew, Brian G.;
- Kingwell, Bronwyn A.
Publication type:
Article
Mechanism of cholesterol efflux in humans after infusion of reconstituted high-density lipoprotein.
Published in:
European Heart Journal, 2012, v. 33, n. 5, p. 657, doi. 10.1093/eurheartj/ehr103
By:
- Hoang, Anh;
- Drew, Brian G.;
- Low, Hann;
- Remaley, Alan T.;
- Nestel, Paul;
- Kingwell, Bronwyn A.;
- Sviridov, Dmitri
Publication type:
Article
ERα regulates lipid metabolism in bone through ATGL and perilipin.
Published in:
Journal of Cellular Biochemistry, 2013, v. 114, n. 6, p. 1306, doi. 10.1002/jcb.24470
By:
- Wend, Korinna;
- Wend, Peter;
- Drew, Brian G.;
- Hevener, Andrea L.;
- Miranda‐Carboni, Gustavo A.;
- Krum, Susan A.
Publication type:
Article
Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling.
Published in:
Science Translational Medicine, 2020, v. 12, n. 555, p. 1, doi. 10.1126/scitranslmed.aax8096
By:
- Zhou, Zhenqi;
- Moore, Timothy M.;
- Drew, Brian G.;
- Ribas, Vicent;
- Wanagat, Jonathan;
- Civelek, Mete;
- Segawa, Mayuko;
- Wolf, Dane M.;
- Norheim, Frode;
- Seldin, Marcus M.;
- Strumwasser, Alexander R.;
- Whitney, Kate A.;
- Lester, Ellen;
- Reddish, Britany R.;
- Vergnes, Laurent;
- Reue, Karen;
- Rajbhandari, Prashant;
- Tontonoz, Peter;
- Lee, Jason;
- Mahata, Sushil K.
Publication type:
Article
Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females.
Published in:
Science Translational Medicine, 2016, v. 8, n. 334, p. 1, doi. 10.1126/scitranslmed.aad3815
By:
- Ribas, Vicent;
- Drew, Brian G.;
- Zhenqi Zhou;
- Phun, Jennifer;
- Kalajian, Nareg Y.;
- Teo Soleymani;
- Daraei, Pedram;
- Widjaja, Kevin;
- Wanagat, Jonathan;
- de Aguiar Vallim, Thomas Q.;
- Fluitt, Amy H.;
- Bensinger, Steven;
- Thuc Le;
- Radu, Caius;
- Whitelegge, Julian P.;
- Beaven, Simon W.;
- Tontonoz, Peter;
- Lusis, Aldons J.;
- Parks, Brian W.;
- Vergnes, Laurent
Publication type:
Article
Mitochondrial fission protein Drp1 inhibition promotes cardiac mesodermal differentiation of human pluripotent stem cells.
Published in:
Cell Death Discovery, 2018, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41420-018-0042-9
By:
- Hoque, Ashfaqul;
- Sivakumaran, Priyadharshini;
- Bond, Simon T.;
- Ling, Naomi X. Y.;
- Kong, Anne M.;
- Scott, John W.;
- Bandara, Nadeeka;
- Hernández, Damián;
- Liu, Guei-Sheung;
- Wong, Raymond C. B.;
- Ryan, Michael T.;
- Hausenloy, Derek J.;
- Kemp, Bruce E.;
- Oakhill, Jonathan S.;
- Drew, Brian G.;
- Pébay, Alice;
- Lim, Shiang Y.
Publication type:
Article
The potential of integrating human and mouse discovery platforms to advance our understanding of cardiometabolic diseases.
Published in:
eLife, 2023, p. 1, doi. 10.7554/eLife.86139
By:
- Jurrjens, Aaron W.;
- Seldin, Marcus M.;
- Giles, Corey;
- Meikle, Peter J.;
- Drew, Brian G.;
- Calkin, Anna C.
Publication type:
Article
Receptor for Advanced Glycation End Products (RAGE) Deficiency Attenuates the Development of Atherosclerosis in Diabetes.
Published in:
Diabetes, 2008, v. 57, n. 9, p. 2461, doi. 10.2337/db07-1808
By:
- Soro-Paavonen, Aino;
- Watson, Anna M. D.;
- Li, Jiaze;
- Paavonen, Karri;
- Koitka, Audrey;
- Calkin, Anna C.;
- Barit, David;
- Coughlan, Melinda T.;
- Drew, Brian G.;
- Lancaster, Graeme I.;
- Thomas, Merlin;
- Forbes, Josephine M.;
- Nawroth, Peter P.;
- Bierhaus, Angelika;
- Cooper, Mark E.;
- Jandeleit-Dahm, Karin A.
Publication type:
Article
Novel Activators of AMP-Kinase as Potential Therapies for Type 2 Diabetes.
Published in:
Diabetes, 2007, v. 56, p. A714
By:
- Drew, Brian G.;
- Henstridge, Darren C.;
- Duffy, Stephen J.;
- Penfold, Sally A.;
- Thomas, Walter G.;
- Natoli, Alaina K.;
- Formosa, Melissa F.;
- Kemp, Bruce E.;
- Steinberg, Gregory R.;
- Kingwell, Bronwyn A.
Publication type:
Article
The Antioxidant Moiety of MitoQ Imparts Minimal Metabolic Effects in Adipose Tissue of High Fat Fed Mice.
Published in:
Frontiers in Physiology, 2019, p. N.PAG, doi. 10.3389/fphys.2019.00543
By:
- Bond, Simon T.;
- Kim, Jisu;
- Calkin, Anna C.;
- Drew, Brian G.
Publication type:
Article
Acute effects of single and repeated mild traumatic brain injury on levels of neurometabolites, lipids, and mitochondrial function in male rats.
Published in:
Frontiers in Molecular Neuroscience, 2023, p. 1, doi. 10.3389/fnmol.2023.1208697
By:
- Allen, Josh;
- Pham, Louise;
- Bond, Simon T.;
- O'Brien, William T.;
- Spitz, Gershon;
- Shultz, Sandy R.;
- Drew, Brian G.;
- Wright, David K.;
- McDonald, Stuart J.
Publication type:
Article
Sex differences in white adipose tissue expansion: emerging molecular mechanisms.
Published in:
Clinical Science, 2021, v. 135, n. 24, p. 2691, doi. 10.1042/CS20210086
By:
- Bond, Simon T.;
- Calkin, Anna C.;
- Drew, Brian G.
Publication type:
Article
Long non-coding RNAs (lncRNAs) in skeletal and cardiac muscle: potential therapeutic and diagnostic targets?
Published in:
Clinical Science, 2016, v. 130, n. 24, p. 2245, doi. 10.1042/CS20160244
By:
- McMullen, Julie R.;
- Drew, Brian G.
Publication type:
Article
A gene therapy targeting medium-chain acyl-CoA dehydrogenase (MCAD) did not protect against diabetes-induced cardiac pathology.
Published in:
Journal of Molecular Medicine, 2024, v. 102, n. 1, p. 95, doi. 10.1007/s00109-023-02397-2
By:
- Weeks, Kate L.;
- Kiriazis, Helen;
- Wadley, Glenn D.;
- Masterman, Emma I.;
- Sergienko, Nicola M.;
- Raaijmakers, Antonia J. A.;
- Trewin, Adam J.;
- Harmawan, Claudia A.;
- Yildiz, Gunes S.;
- Liu, Yingying;
- Drew, Brian G.;
- Gregorevic, Paul;
- Delbridge, Lea M. D.;
- McMullen, Julie R.;
- Bernardo, Bianca C.
Publication type:
Article
Adipose-Derived Extracellular Vesicles: Systemic Messengers and Metabolic Regulators in Health and Disease.
Published in:
Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.837001
By:
- Bond, Simon T.;
- Calkin, Anna C.;
- Drew, Brian G.
Publication type:
Article
Deletion of Trim28 in committed adipocytes promotes obesity but preserves glucose tolerance.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20434-3
By:
- Bond, Simon T.;
- King, Emily J.;
- Henstridge, Darren C.;
- Tran, Adrian;
- Moody, Sarah C.;
- Yang, Christine;
- Liu, Yingying;
- Mellett, Natalie A.;
- Nath, Artika P.;
- Inouye, Michael;
- Tarling, Elizabeth J.;
- de Aguiar Vallim, Thomas Q.;
- Meikle, Peter J.;
- Calkin, Anna C.;
- Drew, Brian G.
Publication type:
Article
Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer's disease.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19473-7
By:
- Huynh, Kevin;
- Lim, Wei Ling Florence;
- Giles, Corey;
- Jayawardana, Kaushala S.;
- Salim, Agus;
- Mellett, Natalie A.;
- Smith, Adam Alexander T.;
- Olshansky, Gavriel;
- Drew, Brian G.;
- Chatterjee, Pratishtha;
- Martins, Ian;
- Laws, Simon M.;
- Bush, Ashley I.;
- Rowe, Christopher C.;
- Villemagne, Victor L.;
- Ames, David;
- Masters, Colin L.;
- Arnold, Matthias;
- Nho, Kwangsik;
- Saykin, Andrew J.
Publication type:
Article
Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis.
Published in:
2016
By:
- Coughlan, Melinda T.;
- Higgins, Gavin C.;
- Tuong-Vi Nguyen;
- Penfold, Sally A.;
- Thallas-Bonke, Vicki;
- Sih Min Tan;
- Ramm, Georg;
- Van Bergen, Nicole J.;
- Henstridge, Darren C.;
- Sourris, Karly C.;
- Harcourt, Brooke E.;
- Trounce, Ian A.;
- Robb, Portia M.;
- Laskowski, Adrienne;
- McGee, Sean L.;
- Genders, Amanda J.;
- Walder, Ken;
- Drew, Brian G.;
- Gregorevic, Paul;
- Hongwei Qian
Publication type:
journal article
Activating HSP72 in Rodent Skeletal Muscle Increases Mitochondrial Number and Oxidative Capacity and Decreases Insulin Resistance.
Published in:
Diabetes, 2014, v. 63, n. 6, p. 1881, doi. 10.2337/db13-0967
By:
- Henstridge, Darren C.;
- Bruce, Clinton R.;
- Drew, Brian G.;
- Tory, Kálmán;
- Kolonics, Attila;
- Estevez, Emma;
- Chung, Jason;
- Watson, Nadine;
- Gardner, Timothy;
- Lee-Young, Robert S.;
- Connor, Timothy;
- Watt, Matthew J.;
- Carpenter, Kevin;
- Hargreaves, Mark;
- McGee, Sean L.;
- Hevener, Andrea L.;
- Febbraio, Mark A.
Publication type:
Article
HSP72 Is a Mitochondrial Stress Sensor Critical for Parkin Action, Oxidative Metabolism, and Insulin Sensitivity in Skeletal Muscle.
Published in:
Diabetes, 2014, v. 63, n. 5, p. 1488, doi. 10.2337/db13-0665
By:
- Drew, Brian G.;
- Ribas, Vicente;
- Jamie A. Le;
- Henstridge, Darren C.;
- Jennifer Phun;
- Zhenqi Zhou;
- Soleymani, Teo;
- Daraei, Pedram;
- Sitz, Daniel;
- Vergnes, Laurent;
- Wanagat, Jonathan;
- Reue, Karen;
- Febbraio, Mark A.;
- Hevener, Andrea L.
Publication type:
Article
Advanced Glycation End Products Are Direct Modulators of β-Cell Function.
Published in:
Diabetes, 2011, v. 60, n. 10, p. 2523, doi. 10.2337/db10-1033
By:
- Coughlan, Melinda T.;
- Yap, Felicia Y. T.;
- Tong, David C. K.;
- Andrikopoulos, Sofianos;
- Gasser, Anna;
- Thallas-Bonke, Vicki;
- Webster, Diane E.;
- Miyazaki, Jun-ichi;
- Kay, Thomas W.;
- Slattery, Robyn M.;
- Kaye, David M.;
- Drew, Brian G.;
- Kingwell, Bronwyn A.;
- Fourlanos, Spiros;
- Groop, Per-Henrik;
- Harrison, Leonard C.;
- Knip, Mikael;
- Forbes, Josephine M.
Publication type:
Article
Interleukin-6 attenuates insulin-mediated increases in endothelial cell signaling but augments skeletal muscle insulin action via differential effects on tumor necrosis factor-alpha expression.
Published in:
2009
By:
- Yuen DY;
- Dwyer RM;
- Matthews VB;
- Zhang L;
- Drew BG;
- Neill B;
- Kingwell BA;
- Clark MG;
- Rattigan S;
- Febbraio MA;
- Yuen, Derek Y C;
- Dwyer, Renee M;
- Matthews, Vance B;
- Zhang, Lei;
- Drew, Brian G;
- Neill, Bronwyn;
- Kingwell, Bronwyn A;
- Clark, Michael G;
- Rattigan, Stephen;
- Febbraio, Mark A
Publication type:
journal article
Interleukin-6 Attenuates Insulin-Mediated Increases in Endothelial Cell Signaling but Augments Skeletal Muscle Insulin Action via Differential Effects on Tumor Necrosis Factor-α Expression.
Published in:
Diabetes, 2009, v. 58, n. 5, p. 1086, doi. 10.2337/db08-0775
By:
- Yuen, Derek Y. C.;
- Dwyer, Renee M.;
- Matthews, Vance B.;
- Lei Zhang;
- Drew, Brian G.;
- Neill, Bronwyn;
- Kingwell, Bronwyn A.;
- Clark, Michael G.;
- Rattigan, Stephen;
- Febbraio, Mark A.
Publication type:
Article

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