Works matching AU Dragunow, Mike

Results: 59

Huntingtin inclusion bodies have distinct immunophenotypes and ubiquitination profiles in the Huntington's disease human cerebral cortex.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-00465-w

By:

Swanson, Molly E. V.;
Tan, Adelie Y. S.;
Tippett, Lynette J.;
Turner, Clinton P.;
Curtis, Maurice A.;
Scotter, Emma L.;
Lashuel, Hilal A.;
Dragunow, Mike;
Faull, Richard L. M.;
Murray, Helen C.;
Singh-Bains, Malvindar K.

Publication type:

Article

Pharmacology of epigenetics in brain disorders.

Published in:

British Journal of Pharmacology, 2010, v. 159, n. 2, p. 285, doi. 10.1111/j.1476-5381.2009.00526.x

By:

Narayan, Pritika;
Dragunow, Mike

Publication type:

Article

Human pericytes degrade diverse α-synuclein aggregates.

Published in:

PLoS ONE, 2022, v. 17, n. 11, p. 1, doi. 10.1371/journal.pone.0277658

By:

Dieriks, Birger Victor;
Highet, Blake;
Alik, Ania;
Bellande, Tracy;
Stevenson, Taylor J.;
Low, Victoria;
Park, Thomas I-H;
Correia, Jason;
Schweder, Patrick;
Faull, Richard L. M.;
Melki, Ronald;
Curtis, Maurice A.;
Dragunow, Mike

Publication type:

Article

Cardiac glycosides target barrier inflammation of the vasculature, meninges and choroid plexus.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-01787-x

By:

Jansson, Deidre;
Dieriks, Victor Birger;
Rustenhoven, Justin;
Smyth, Leon C. D.;
Scotter, Emma;
Aalderink, Miranda;
Feng, Sheryl;
Johnson, Rebecca;
Schweder, Patrick;
Mee, Edward;
Heppner, Peter;
Turner, Clinton;
Curtis, Maurice;
Faull, Richard;
Dragunow, Mike

Publication type:

Article

Cell Type–Specific Nuclei Markers: The Need for Human Brain Research to Go Nuclear.

Published in:

Neuroscientist, 2023, v. 29, n. 1, p. 41, doi. 10.1177/10738584211037351

By:

Wiseman, James A.;
Dragunow, Mike;
I.-H. Park, Thomas

Publication type:

Article

The Use of Heptamethine Cyanine Dyes as Drug-Conjugate Systems in the Treatment of Primary and Metastatic Brain Tumors.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.654921

By:

Cooper, Elizabeth;
Choi, Peter J.;
Denny, William A.;
Jose, Jiney;
Dragunow, Mike;
Park, Thomas I.-H.

Publication type:

Article

PU.1 regulates Alzheimer’s disease-associated genes in primary human microglia.

Published in:

Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0277-1

By:

Rustenhoven, Justin;
Smith, Amy M.;
Smyth, Leon C.;
Jansson, Deidre;
Scotter, Emma L.;
Swanson, Molly E. V.;
Aalderink, Miranda;
Coppieters, Natacha;
Narayan, Pritika;
Handley, Renee;
Overall, Chris;
Park, Thomas I. H.;
Schweder, Patrick;
Heppner, Peter;
Curtis, Maurice A.;
Faull, Richard L. M.;
Dragunow, Mike

Publication type:

Article

The transcription factor PU.1 is critical for viability and function of human brain microglia.

Published in:

Glia (0894-1491), 2013, v. 61, n. 6, p. 929, doi. 10.1002/glia.22486

By:

Smith, Amy M.;
Gibbons, Hannah M.;
Oldfield, Robyn L.;
Bergin, Peter M.;
Mee, Edward W.;
Faull, Richard L. M.;
Dragunow, Mike

Publication type:

Article

Characterization of volumetric growth of intracranial meningiomas in Māori and Pasifika populations in New Zealand.

Published in:

ANZ Journal of Surgery, 2022, v. 92, n. 4, p. 848, doi. 10.1111/ans.17564

By:

Davis, Brendan;
Beldishevski‐Shotadze, Otari;
Ibrahim, Zaid;
McHugh, Frances;
Turner, Clinton;
Olson, Sarah;
Faull, Richard;
Dragunow, Mike;
Law, Andrew J. J.;
Correia, Jason A.

Publication type:

Article

Motor neuron disease mortality rates in New Zealand 1992-2013.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2018, v. 19, n. 3/4, p. 285, doi. 10.1080/21678421.2018.1432660

By:

Cao, Maize C.;
Chancellor, Andrew;
Charleston, Alison;
Dragunow, Mike;
Scotter, Emma L.

Publication type:

Article

A NOVEL HIGH-THROUGHPUT ASSAY FOR THE QUANTITATIVE ASSESSMENT OF RECEPTOR TRAFFICKING.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2008, v. 35, n. 11, p. 1377, doi. 10.1111/j.1440-1681.2008.04991.x

By:

Grimsey, Natasha L;
Narayan, Pritika J;
Dragunow, Mike;
Glass, Michelle

Publication type:

Article

Quantification of tumorsphere migration with a physics‐based machine learning method.

Published in:

Cytometry. Part A, 2023, v. 103, n. 6, p. 518, doi. 10.1002/cyto.a.24722

By:

Vong, Chun Kiet;
Wang, Alan;
Dragunow, Mike;
Park, Thomas I.‐H.;
Shim, Vickie

Publication type:

Article

Routine culture and study of adult human brain cells from neurosurgical specimens.

Published in:

Nature Protocols, 2022, v. 17, n. 2, p. 190, doi. 10.1038/s41596-021-00637-8

By:

Park, Thomas I.-H.;
Smyth, Leon C. D.;
Aalderink, Miranda;
Woolf, Zoe R.;
Rustenhoven, Justin;
Lee, Kevin;
Jansson, Deidre;
Smith, Amy;
Feng, Sheryl;
Correia, Jason;
Heppner, Peter;
Schweder, Patrick;
Mee, Edward;
Dragunow, Mike

Publication type:

Article

Preparation, construction and high-throughput automated analysis of human brain tissue microarrays for neurodegenerative disease drug development.

Published in:

Nature Protocols, 2021, v. 16, n. 4, p. 2308, doi. 10.1038/s41596-021-00503-7

By:

Singh-Bains, Malvindar K.;
Mehrabi, Nasim F.;
Tan, Adelie Y. S.;
Faull, Richard L. M.;
Dragunow, Mike

Publication type:

Article

Characterization of NTera2/D1 cells as a model system for the investigation of cannabinoid function in human neurons and astrocytes.

Published in:

Journal of Neuroscience Research, 2011, v. 89, n. 10, p. 1685, doi. 10.1002/jnr.22692

By:

Goodfellow, Catherine E.;
Graham, Scott E.;
Dragunow, Mike;
Glass, Michelle

Publication type:

Article

Erratum to: Studying Human Brain Inflammation in Leptomeningeal and Choroid Plexus Explant Cultures.

Published in:

2016

By:

Dragunow, Mike;
Feng, Sheryl;
Rustenhoven, Justin;
Curtis, Maurice;
Faull, Richard

Publication type:

Erratum

Studying Human Brain Inflammation in Leptomeningeal and Choroid Plexus Explant Cultures.

Published in:

Neurochemical Research, 2016, v. 41, n. 3, p. 579, doi. 10.1007/s11064-015-1682-2

By:

Dragunow, Mike;
Feng, Sheryl;
Rustenhoven, Justin;
Curtis, Maurice;
Faull, Richard

Publication type:

Article

TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models.

Published in:

EMBO Journal, 2020, v. 39, n. 17, p. 1, doi. 10.15252/embj.2020104671

By:

Hegde, Ramanath Narayana;
Chiki, Anass;
Petricca, Lara;
Martufi, Paola;
Arbez, Nicolas;
Mouchiroud, Laurent;
Auwerx, Johan;
Landles, Christian;
Bates, Gillian P;
Singh‐Bains, Malvindar K;
Dragunow, Mike;
Curtis, Maurice A;
Faull, Richard LM;
Ross, Christopher A;
Caricasole, Andrea;
Lashuel, Hilal A

Publication type:

Article

TGF-beta1 regulates human brain pericyte inflammatory processes involved in neurovasculature function.

Published in:

2016

By:

Rustenhoven, Justin;
Aalderink, Miranda;
Scotter, Emma L.;
Oldfield, Robyn L.;
Bergin, Peter S.;
Mee, Edward W.;
Graham, E. Scott;
Faull, Richard L. M.;
Curtis, Maurice A.;
Park, Thomas I.-H.;
Dragunow, Mike

Publication type:

journal article

Erratum to: A role for human brain pericytes in neuroinflammation.

Published in:

2015

By:

Jansson, Deidre;
Rustenhoven, Justin;
Feng, Sheryl;
Hurley, Daniel;
Oldfield, Robyn L;
Bergin, Peter S;
Mee, Edward W;
Faull, Richard L M;
Dragunow, Mike

Publication type:

Correction Notice

A role for human brain pericytes in neuroinflammation.

Published in:

Journal of Neuroinflammation, 2014, v. 11, n. 1, p. 1, doi. 10.1186/1742-2094-11-104

By:

Jansson, Deidre;
Rustenhoven, Justin;
Feng, Sheryl;
Hurley, Daniel;
Oldfield, Robyn L.;
Bergin, Peter S.;
Mee, Edward W.;
Faull, Richard L.;
Dragunow, Mike

Publication type:

Article

A role for human brain pericytes in neuroinflammation.

Published in:

2014

By:

Jansson, Deidre;
Rustenhoven, Justin;
Feng, Sheryl;
Hurley, Daniel;
Oldfield, Robyn L;
Bergin, Peter S;
Mee, Edward W;
Faull, Richard Lm;
Dragunow, Mike;
Faull, Richard L M

Publication type:

journal article

M-CSF increases proliferation and phagocytosis while modulating receptor and transcription factor expression in adult human microglia.

Published in:

Journal of Neuroinflammation, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-2094-10-85

By:

Smith, Amy M.;
Gibbons, Hannah M.;
Oldfield, Robyn L.;
Bergin, Peter M.;
Mee, Edward W.;
Curtis, Maurice A.;
Faull, Richard L. M.;
Dragunow, Mike

Publication type:

Article

Enhanced detection of distinct honeycomb-structured neuronal SMARCC2 cytobodies in Parkinson's Disease via Cyclic Heat-Induced Epitope Retrieval (CHIER).

Published in:

PLoS ONE, 2024, v. 19, n. 12, p. 1, doi. 10.1371/journal.pone.0315183

By:

Carmichael-Lowe, Amber;
Fleming, Brionne;
Reddy, Kreesan;
Wiseman, James;
Yin, Eden Paige;
Turner, Clinton P.;
Faull, Richard L. M.;
Curtis, Maurice A.;
Dragunow, Mike;
Dieriks, Birger Victor

Publication type:

Article

AAV-Mediated gene delivery of BDNF or GDNF is neuroprotective in a model of huntington disease

Published in:

Molecular Therapy, 2004, v. 9, n. 5, p. 682, doi. 10.1016/j.ymthe.2004.02.016

By:

Kells, Adrian P.;
Fong, Dahna M.;
Dragunow, Mike;
During, Matthew J.;
Young, Deborah;
Connor, Bronwen

Publication type:

Article

Modelling physiological and pathological conditions to study pericyte biology in brain function and dysfunction.

Published in:

2018

By:

Rustenhoven, Justin;
Smyth, Leon C.;
Jansson, Deidre;
Schweder, Patrick;
Aalderink, Miranda;
Scotter, Emma L.;
Mee, Edward W.;
Faull, Richard L. M.;
Park, Thomas I.-H.;
Dragunow, Mike

Publication type:

journal article

High-content analysis in neuroscience.

Published in:

Nature Reviews Neuroscience, 2008, v. 9, n. 10, p. 779, doi. 10.1038/nrn2492

By:

Dragunow, Mike

Publication type:

Article

Neutrophil-vascular interactions drive myeloperoxidase accumulation in the brain in Alzheimer's disease.

Published in:

Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01347-2

By:

Smyth, Leon C. D.;
Murray, Helen C.;
Hill, Madison;
van Leeuwen, Eve;
Highet, Blake;
Magon, Nicholas J.;
Osanlouy, Mahyar;
Mathiesen, Sophie N.;
Mockett, Bruce;
Singh-Bains, Malvindar K.;
Morris, Vanessa K.;
Clarkson, Andrew N.;
Curtis, Maurice A.;
Abraham, Wickliffe C.;
Hughes, Stephanie M.;
Faull, Richard L. M.;
Kettle, Anthony J.;
Dragunow, Mike;
Hampton, Mark B.

Publication type:

Article

Blood-spinal cord barrier leakage is independent of motor neuron pathology in ALS.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01244-0

By:

Waters, Sarah;
Swanson, Molly E. V.;
Dieriks, Birger V.;
Zhang, Yibin B.;
Grimsey, Natasha L.;
Murray, Helen C.;
Turner, Clinton;
Waldvogel, Henry J.;
Faull, Richard L. M.;
An, Jiyan;
Bowser, Robert;
Curtis, Maurice A.;
Dragunow, Mike;
Scotter, Emma

Publication type:

Article

Effects of preterm birth induced with or without exogenous glucocorticoids on the ovine glucose–insulin axis.

Published in:

Journal of Developmental Origins of Health & Disease, 2021, v. 12, n. 1, p. 58, doi. 10.1017/S2040174419000916

By:

Bansal, Amita;
Alsweiler, Jane M.;
Oliver, Mark H.;
Jaquiery, Anne;
Phua, Hui Hui;
Dragunow, Mike;
de Matteo, Rob;
Harding, Jane E.;
Bloomfield, Frank H.

Publication type:

Article

Complement peptide C3a stimulates neural plasticity after experimental brain ischaemia.

Published in:

2017

By:

Stokowska, Anna;
Atkins, Alison L.;
Morán, Javier;
Pekny, Tulen;
Bulmer, Linda;
Pascoe, Michaela C.;
Barnum, Scott R.;
Wetsel, Rick A.;
Nilsson, Jonas A.;
Dragunow, Mike;
Pekna, Marcela

Publication type:

journal article

Cerebellar degeneration correlates with motor symptoms in Huntington disease.

Published in:

2019

By:

Singh‐Bains, Malvindar K.;
Mehrabi, Nasim F.;
Sehji, Tvesa;
Austria, Micah D. R.;
Tan, Adelie Y. S.;
Tippett, Lynette J.;
Dragunow, Mike;
Waldvogel, Henry J.;
Faull, Richard L. M.;
Singh-Bains, Malvindar K

Publication type:

journal article

Disrupted vasculature and blood-brain barrier in Huntington disease.

Published in:

Annals of Neurology, 2015, v. 78, n. 2, p. 158, doi. 10.1002/ana.24445

By:

Waldvogel, Henry J.;
Dragunow, Mike;
Faull, Richard L. M.

Publication type:

Article

Receptor for complement peptide C3a: a therapeutic target for neonatal hypoxic-ischemic brain injury.

Published in:

FASEB Journal, 2013, v. 27, n. 9, p. 3797, doi. 10.1096/fj.13-230011

By:

Järlestedt, Katarina;
Rousset, Catherine I.;
Ståhlberg, Anders;
Sourkova, Hana;
Atkins, Alison L.;
Thornton, Claire;
Barnum, Scott R.;
Wetsel, Rick A.;
Dragunow, Mike;
Pekny, Milos;
Mallard, Carina;
Hagberg, Henrik;
Pekna, Marcela

Publication type:

Article

Insulin and IGF1 modulate turnover of polysialylated neural cell adhesion molecule ( PSA- NCAM) in a process involving specific extracellular matrix components.

Published in:

Journal of Neurochemistry, 2013, v. 126, n. 6, p. 758, doi. 10.1111/jnc.12363

By:

Monzo, Hector J.;
Park, Thomas I. H.;
Dieriks, Birger V.;
Jansson, Deidre;
Faull, Richard L. M.;
Dragunow, Mike;
Curtis, Maurice A.

Publication type:

Article

Serum biomarkers of neuroinflammation and blood-brain barrier leakage in amyotrophic lateral sclerosis.

Published in:

BMC Neurology, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12883-022-02730-1

By:

Cao, Maize C.;
Cawston, Erin E.;
Chen, Grace;
Brooks, Collin;
Douwes, Jeroen;
McLean, Dave;
Graham, E. Scott;
Dragunow, Mike;
Scotter, Emma L.

Publication type:

Article

The adult human brain in preclinical drug development.

Published in:

Nature Reviews Drug Discovery, 2008, v. 7, n. 8, p. 659, doi. 10.1038/nrd2617

By:

Dragunow, Mike

Publication type:

Article

M<sub>3</sub> muscarinic receptors as targets for drug development in neurodegenerative disorders.

Published in:

2008

By:

Dragunow, Mike

Publication type:

Letter

Quantitative immunohistochemical analysis of myeloid cell marker expression in human cortex captures microglia heterogeneity with anatomical context.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-68086-z

By:

Swanson, Molly E. V.;
Murray, Helen C.;
Ryan, Brigid;
Faull, Richard L. M.;
Dragunow, Mike;
Curtis, Maurice A.

Publication type:

Article

Adult Human Glia, Pericytes and Meningeal Fibroblasts Respond Similarly to IFNy but Not to TGFβ<sub>1</sub> or M-CSF.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0080463

By:

Smith, Amy M.;
Graham, E. Scott;
Feng, Sheryl Xia;
Oldfield, Robyn L.;
Bergin, Peter M.;
Mee, Edward W.;
Faull, Richard L. M.;
Curtis, Maurice A.;
Dragunow, Mike

Publication type:

Article

M1 Muscarinic Receptor Activation Mediates Cell Death in M1-HEK293 Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0072011

By:

Graham, E. Scott;
Woo, Kerhan K.;
Aalderink, Miranda;
Fry, Sandie;
Greenwood, Jeffrey M.;
Glass, Michelle;
Dragunow, Mike

Publication type:

Article

Single-cell image analysis reveals over-expression of organic anion transporting polypeptides (OATPs) in human glioblastoma tissue.

Published in:

Neuro-Oncology Advances, 2022, v. 4, n. 1, p. 1, doi. 10.1093/noajnl/vdac166

By:

Cooper, Elizabeth;
Woolf, Zoe;
Swanson, Molly E. V.;
Correia, Jason;
Mee, Edward;
Heppner, Peter;
Turner, Clinton;
Faull, Richard L. M.;
Scotter, Emma L.;
Denny, William A.;
Choi, Peter J.;
Dragunow, Mike;
Jose, Jiney;
Park, Thomas I.-H.;
Schweder, Patrick

Publication type:

Article

Identification of a dysfunctional microglial population in human Alzheimer's disease cortex using novel single-cell histology image analysis.

Published in:

Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. N.PAG, doi. 10.1186/s40478-020-01047-9

By:

Swanson, Molly E. V.;
Scotter, Emma L.;
Smyth, Leon C. D.;
Murray, Helen C.;
Ryan, Brigid;
Turner, Clinton;
Faull, Richard L. M.;
Dragunow, Mike;
Curtis, Maurice A.

Publication type:

Article

TMIC-21. THE POTENTIAL CONTRIBUTION OF PERICYTES TO GLIOBLASTOMA MULTIFORME TUMOUR MICRO-ENVIRONMENT IMMUNOSUPPRESSION VIA DAMPENED EXPRESSION OF ICAM-1, VCAM-1 AND MCP-1.

Published in:

Neuro-Oncology, 2018, v. 20, p. vi260, doi. 10.1093/neuonc/noy148.1080

By:

Macapagal, Jena;
Park, Thomas;
Joret, Maximillian;
Rustenhoven, Justin;
Dieriks, Birger;
Faull, Richard;
Schweder, Patrick;
Dragunow, Mike

Publication type:

Article

ANGI-03. PSA-NCAM IN GLIOBLASTOMA – A NEGATIVE PROGNOSTIC MARKER AND A THERAPEUTIC TARGET?

Published in:

Neuro-Oncology, 2018, v. 20, p. vi28, doi. 10.1093/neuonc/noy148.105

By:

Park, Thomas;
Kim, Bernard;
Macapagal, Jena;
Dieriks, Birger;
Schweder, Patrick;
Heppner, Peter;
Turner, Clinton;
Curtis, Maurice;
Dragunow, Mike

Publication type:

Article

Microrna regulation of human brain pericytes.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P777, doi. 10.1016/j.jalz.2015.06.1736

By:

Aalderink, Miranda;
Curtis, Maurice A.;
Faull, Richard L.M.;
Dragunow, Mike

Publication type:

Article

Age-related meningeal extracellular matrix remodeling compromises CNS lymphatic function.

Published in:

Journal of Neuroinflammation, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12974-025-03436-0

By:

Hitpass Romero, Kate;
Stevenson, Taylor J.;
Smyth, Leon C. D.;
Watkin, Ben;
McCullough, Samuel J.C.;
Vinnell, Luca;
Smith, Amy M.;
Schweder, Patrick;
Correia, Jason A.;
Kipnis, Jonathan;
Dragunow, Mike;
Rustenhoven, Justin

Publication type:

Article

Unique and shared inflammatory profiles of human brain endothelia and pericytes.

Published in:

2018

By:

Smyth, Leon C. D.;
Rustenhoven, Justin;
Park, Thomas I.-H.;
Schweder, Patrick;
Jansson, Deidre;
Heppner, Peter A.;
O'Carroll, Simon J.;
Mee, Edward W.;
Faull, Richard L. M.;
Curtis, Maurice;
Dragunow, Mike

Publication type:

journal article

α-synuclein transfer through tunneling nanotubes occurs in SH-SY5Y cells and primary brain pericytes from Parkinson's disease patients.

Published in:

Scientific Reports, 2017, p. 42984, doi. 10.1038/srep42984

By:

Dieriks, Birger Victor;
Park, Thomas I-H.;
Fourie, Chantelle;
Faull, Richard L. M.;
Dragunow, Mike;
Curtis, Maurice A.

Publication type:

Article

Cultured pericytes from human brain show phenotypic and functional differences associated with differential CD90 expression.

Published in:

Scientific Reports, 2016, p. 26587, doi. 10.1038/srep26587

By:

Park, Thomas I-H.;
Feisst, Vaughan;
Brooks, Anna E. S.;
Rustenhoven, Justin;
Monzo, Hector J.;
Feng, Sheryl X.;
Mee, Edward W.;
Bergin, Peter S.;
Oldfield, Robyn;
Graham, E. Scott;
Curtis, Maurice A.;
Faull, Richard L. M.;
Dunbar, P. Rod;
Dragunow, Mike

Publication type:

Article