Works by Downes, Michelle R.

Results: 43

Current practices in prostate pathology reporting: results from a survey of genitourinary and general pathologists.

Published in:

Histopathology, 2025, v. 87, n. 2, p. 206, doi. 10.1111/his.15469

By:

Nourbakshs, Mahra;
Du, Liping;
Acosta, Andres M;
Alaghehbandan, Reza;
Amin, Ali;
Amin, Mahul B;
Aron, Manju;
Berney, Daniel;
Brimo, Fadi;
Chan, Emily;
Cheng, Liang;
Colecchia, Maurizio;
Dhillon, Jasreman;
Downes, Michelle R;
Evans, Andrew J;
Harik, Lara R;
Hassan, Oudai;
Haider, Aiman;
Humphrey, Peter A;
Jha, Shilpy

Publication type:

Article

A novel association of gastric ischaemia and aortic coarctation.

Published in:

2010

By:

Turowski, Carmen;
Downes, Michelle R.;
Devaney, Deirdre M.;
Donoghue, Veronica;
Gillick, John

Publication type:

journal article

Urinary markers for prostate cancer.

Published in:

BJU International, 2007, v. 99, n. 2, p. 263, doi. 10.1111/j.1464-410X.2006.06610.x

By:

Downes, Michelle R.;
Byrne, Jennifer C.;
Pennington, Stephen R.;
Dunn, Michael J.;
Fitzpatrick, John M.;
Watson, R. William G.

Publication type:

Article

Prostate cancer reshapes the secreted and extracellular vesicle urinary proteomes.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49424-5

By:

Khoo, Amanda;
Govindarajan, Meinusha;
Qiu, Zhuyu;
Liu, Lydia Y.;
Ignatchenko, Vladimir;
Waas, Matthew;
Macklin, Andrew;
Keszei, Alexander;
Neu, Sarah;
Main, Brian P.;
Yang, Lifang;
Lance, Raymond S.;
Downes, Michelle R.;
Semmes, O. John;
Vesprini, Danny;
Liu, Stanley K.;
Nyalwidhe, Julius O.;
Boutros, Paul C.;
Kislinger, Thomas

Publication type:

Article

Modulating ATP binding cassette transporters in papillary renal cell carcinoma type 2 enhances its response to targeted molecular therapy.

Published in:

Molecular Oncology, 2018, v. 12, n. 10, p. 1673, doi. 10.1002/1878-0261.12346

By:

Saleeb, Rola M.;
Farag, Mina;
Lichner, Zsuzsanna;
Brimo, Fadi;
Bartlett, Jenni;
Bjarnason, Georg;
Finelli, Antonio;
Rontondo, Fabio;
Downes, Michelle R.;
Yousef, George M.

Publication type:

Article

Nephrogenic Adenoma: A Pitfall on Frozen Section of Urethral Strictures.

Published in:

International Journal of Surgical Pathology, 2025, v. 33, n. 3, p. 656, doi. 10.1177/10668969241286069

By:

Oberc, Alexander M.;
Sherman, Christopher;
Downes, Michelle R.

Publication type:

Article

Morphologic Pattern, Frequency, and Spatial Distribution of Lymphovascular Invasion Foci in Radical Prostatectomy Specimens.

Published in:

International Journal of Surgical Pathology, 2023, v. 31, n. 6, p. 939, doi. 10.1177/10668969221110456

By:

Al Qa'qa', Shifaa';
Downes, Michelle R.;
Jain, Rahi;
van der Kwast, Theodorus

Publication type:

Article

The Search for the Optimal cut-off Value of p53-Immunohistochemistry to Predict Prognosis of Invasive Bladder Cancer: A Multi-Center, Multi-Laboratory Analysis.

Published in:

International Journal of Surgical Pathology, 2023, v. 31, n. 2, p. 157, doi. 10.1177/10668969221095173

By:

Mertens, Laura S.;
Claps, Francesco;
Mayr, Roman;
Hodgson, Anjelica;
Shariat, Shahrokh F.;
Hippe, Katrin;
Neuzillet, Yann;
Sanders, Joyce;
Burger, Maximilian;
Pouessel, Damien;
Otto, Wolfgang;
van der Kwast, Theo H.;
Lotan, Yair;
Allory, Yves;
Downes, Michelle R.;
van Rhijn, Bas W.G.

Publication type:

Article

A Practical Approach to Investigating Cross-Contaminants in the Anatomical Pathology Laboratory.

Published in:

International Journal of Surgical Pathology, 2020, v. 28, n. 7, p. 700, doi. 10.1177/1066896920913110

By:

Hodgson, Anjelica J.;
Shang, Yan Ming;
Boulianne, Patrice;
Downes, Michelle R.;
Hwang, David;
Slodkowska, Elzbieta

Publication type:

Article

A Novel Primary Cell Line Model of Localized Prostate Cancer and Radioresistance—A Role for Nicotinamide N-Methyltransferase.

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 819, doi. 10.3390/cells14110819

By:

Wright, Jessica A.;
White, Stephanie D.;
Frame, Gavin;
Bosiljkov, Ana;
Khan, Shahbaz;
Haas, Roni;
Yang, Qian;
Sheng, Minzhi;
Huang, Xiaoyong;
Higgins, Geoff S.;
Mills, Ian;
Downes, Michelle R.;
Vesprini, Danny;
Chung, Hans T.;
Screaton, Robert A.;
Leong, Hon S.;
Boutros, Paul C.;
Kislinger, Thomas;
Liu, Stanley K.

Publication type:

Article

Redefining and capturing pre-analytic deficiencies in an anatomical pathology laboratory: a quality improvement initiative.

Published in:

Virchows Archiv: European Journal of Pathology, 2024, v. 484, n. 5, p. 743, doi. 10.1007/s00428-023-03611-9

By:

Truong, Tra;
Roopchard, Preeya;
Olkhov-Mitsel, Ekaterina;
Farahvash, Armin;
Sanders, Gail;
Jordan, Tanya;
Ghorab, Zeina;
Slodkowska, Elzbieta;
Downes, Michelle R.

Publication type:

Article

The impact of pre-analytical parameters on class II biomarkers by immunohistochemistry: concordance across four tissue processing protocols.

Published in:

2021

By:

Xu, Bin;
Alminawi, Samira;
Boulianne, Patrice;
Shang, Yan Ming;
Downes, Michelle R.;
Slodkowska, Elzbieta

Publication type:

journal article

Evaluation of cancer testis antigen (CT10, PRAME) and MHC I expression in high-grade urothelial carcinoma of the bladder.

Published in:

Virchows Archiv: European Journal of Pathology, 2020, v. 476, n. 4, p. 535, doi. 10.1007/s00428-019-02661-2

By:

Hodgson, Anjelica;
Jungbluth, Achim A.;
Katabi, Nora;
Xu, Bin;
Downes, Michelle R.

Publication type:

Article

Evaluation of cancer testis antigen (CT10, PRAME) and MHC I expression in high-grade urothelial carcinoma of the bladder.

Published in:

2019

By:

Hodgson, Anjelica;
Jungbluth, Achim A;
Katabi, Nora;
Xu, Bin;
Downes, Michelle R

Publication type:

journal article

Engineering the future of 3D pathology.

Published in:

Journal of Pathology: Clinical Research, 2024, v. 10, n. 1, p. 1, doi. 10.1002/cjp2.347

By:

Liu, Jonathan TC;
Chow, Sarah SL;
Colling, Richard;
Downes, Michelle R;
Farré, Xavier;
Humphrey, Peter;
Janowczyk, Andrew;
Mirtti, Tuomas;
Verrill, Clare;
Zlobec, Inti;
True, Lawrence D

Publication type:

Article

Target prostate biopsies: How best to report in synoptic format?

Published in:

Canadian Urological Association Journal, 2022, v. 16, n. 4, p. E227, doi. 10.5489/cuaj.7460

By:

Downes, Michelle R.;
Srigley, John R.;
Loblaw, Andrew;
Perlis, Nathan;
Ghai, Sangeet;
van der Kwast, Theodorus

Publication type:

Article

Development of a Clinically Applicable NanoString-Based Gene Expression Classifier for Muscle-Invasive Bladder Cancer Molecular Stratification.

Published in:

Cancers, 2022, v. 14, n. 19, p. 4911, doi. 10.3390/cancers14194911

By:

Olkhov-Mitsel, Ekaterina;
Yu, Yanhong;
Lajkosz, Katherine;
Liu, Stanley K.;
Vesprini, Danny;
Sherman, Christopher G.;
Downes, Michelle R.

Publication type:

Article

Fasting status as a consideration for human serum collection and preparation prior to depletion and analysis.

Published in:

Electrophoresis, 2008, v. 29, n. 14, p. 3055, doi. 10.1002/elps.200700933

By:

Byrne, Jennifer C.;
Downes, Michelle R.;
O'Donoghue, Niaobh;
Fitzpatrick, John M.;
Dunn, Michael J.;
Watson, Ronald W. G.

Publication type:

Article

MTAP protein status is highly concordant with CDKN2A fluorescent in situ hybridization and allows stratification of the luminal subtype in muscle‐invasive bladder cancer.

Published in:

Histopathology, 2025, v. 86, n. 3, p. 352, doi. 10.1111/his.15324

By:

Olkhov‐Mitsel, Ekaterina;
Oberc, Alexander;
Craddock, Kenneth J;
Sherman, Christopher;
Slodkowska, Elzbieta;
Downes, Michelle R

Publication type:

Article

Inter‐ and intraobserver agreement of programmed death ligand 1 scoring in head and neck squamous cell carcinoma, urothelial carcinoma and breast carcinoma.

Published in:

Histopathology, 2020, v. 76, n. 2, p. 191, doi. 10.1111/his.13946

By:

Downes, Michelle R;
Slodkowska, Elzbieta;
Katabi, Nora;
Jungbluth, Achim A;
Xu, Bin

Publication type:

Article

Inter‐ and intraobserver agreement of programmed death ligand 1 scoring in head and neck squamous cell carcinoma, urothelial carcinoma and breast carcinoma.

Published in:

Histopathology, 2020, v. 76, n. 1, p. 191, doi. 10.1111/his.13946

By:

Downes, Michelle R;
Slodkowska, Elzbieta;
Katabi, Nora;
Jungbluth, Achim A;
Xu, Bin

Publication type:

Article

Gleason grade patterns in nodal metastasis and corresponding prostatectomy specimens: impact on patient outcome.

Published in:

Histopathology, 2019, v. 75, n. 5, p. 715, doi. 10.1111/his.13938

By:

Downes, Michelle R;
Xu, Bin;
Kwast, Theo H

Publication type:

Article

Concordance of biopsy and prostatectomy diagnosis of intraductal and cribriform carcinoma in a prospectively collected data set.

Published in:

Histopathology, 2019, v. 74, n. 3, p. 474, doi. 10.1111/his.13747

By:

Masoomian, Mehdi;
Downes, Michelle R.;
Sweet, Joan;
Cheung, Carol;
Evans, Andrew J.;
Fleshner, Neil;
Maganti, Manjula;
Van der Kwast, Theodorus

Publication type:

Article

Basal‐subtype bladder tumours show a 'hot' immunophenotype.

Published in:

Histopathology, 2018, v. 73, n. 5, p. 748, doi. 10.1111/his.13696

By:

Hodgson, Anjelica;
Liu, Stanley K;
Vesprini, Danny;
Xu, Bin;
Downes, Michelle R

Publication type:

Article

Prognostic pathological factors in radical cystectomy after neoadjuvant chemotherapy.

Published in:

Histopathology, 2018, v. 73, n. 5, p. 732, doi. 10.1111/his.13654

By:

Brimo, Fadi;
Downes, Michelle R;
Jamaspishvili, Tamara;
Berman, David;
Barkan, Guliz A;
Athanazio, Daniel;
Abro, Schuharazad;
Visram, Kash;
Yilmaz, Asli;
Solanki, Shraddha;
Hahn, Elan;
Siemens, Robert;
Kassouf, Wassim;
Trpkov, Kiril

Publication type:

Article

Prostate carcinoma with amphicrine features: further refining the spectrum of neuroendocrine differentiation in tumours of primary prostatic origin?

Published in:

Histopathology, 2017, v. 71, n. 6, p. 926, doi. 10.1111/his.13330

By:

Prendeville, Susan;
Al‐Bozom, Issam;
Compérat, Eva;
Sweet, Joan;
Evans, Andrew J;
Ben‐Gashir, Mohamed;
Mete, Ozgur;
Kwast, Theodorus H;
Downes, Michelle R

Publication type:

Article

p53 immunohistochemistry in high-grade urothelial carcinoma of the bladder is prognostically significant.

Published in:

Histopathology, 2017, v. 71, n. 2, p. 296, doi. 10.1111/his.13225

By:

Hodgson, Anjelica;
Xu, Bin;
Downes, Michelle R

Publication type:

Article

Analysis of papillary urothelial carcinomas of the bladder with grade heterogeneity: supportive evidence for an early role of CDKN2A deletions in the FGFR3 pathway.

Published in:

Histopathology, 2017, v. 70, n. 2, p. 281, doi. 10.1111/his.13063

By:

Downes, Michelle R;
Weening, Berber;
Rhijn, Bas W G;
Have, Cherry L;
Treurniet, Kilian M;
Kwast, Theodorus H

Publication type:

Article

Review of findings in prophylactic gynaecological specimens in Lynch syndrome with literature review and recommendations for grossing.

Published in:

Histopathology, 2014, v. 65, n. 2, p. 228, doi. 10.1111/his.12386

By:

Downes, Michelle R;
Allo, Ghassan;
McCluggage, W Glenn;
Sy, Keiyan;
Ferguson, Sarah E;
Aronson, Melyssa;
Pollett, Aaron;
Gallinger, Steve;
Bilbily, Elaine;
Shaw, Pat;
Clarke, Blaise A

Publication type:

Article

Prevalence of programmed death-ligand 1 (PD-L1) positivity in invasive urothelial carcinoma and its correlation with clinicopathologic characteristics in canadian patients.

Published in:

Canadian Journal of Pathology, 2019, v. 11, n. 1, p. 44

By:

Bigras, Gilbert;
Downes, Michelle R.;
Tavassoli, Peyman;
Fathers, Kelly;
Xue, Cloris;
DeMarco, Patricia;
Cheung, Carol C.

Publication type:

Article

Modulating ATP binding cassette (ABC) transporters in papillary renal cell carcinoma type 2 enhances its response to targeted molecular therapies.

Published in:

Canadian Journal of Pathology, 2018, v. 10, p. 53

By:

Saleeb, Rola M.;
Farag, Mina;
Lichner, Zsuzsanna;
Brimo, Fadi;
Rotondo, Fabio;
Downes, Michelle R.;
Yousef, George M.

Publication type:

Article

The prevalence of Programmed Death Ligand 1 (PD-L1) in tumour-infiltrating immune cells is common in Canadian patients with invasive urothelial carcinoma.

Published in:

Canadian Journal of Pathology, 2018, v. 10, p. 7

By:

Bigras, Gilbert;
Brimo, Fadi;
Downes, Michelle R.;
Latour, Mathieu;
Tavassoli, Peyman;
Fathers, Kelly;
Xue, Cloris;
DeMarco, Patricia;
Cheung, Carol

Publication type:

Article

Abnormal/wild type p53 expression in bladder cancer shows better correlation with FGFR3 mutation status than the commonly used 10% p53 cut-off.

Published in:

Canadian Journal of Pathology, 2018, v. 10, p. 4

By:

Hodgson, Anjelica;
Bin Xu;
van Rhijn, Bas W. G.;
van der Kwast, Theo;
Downes, Michelle R.

Publication type:

Article

COMMENTARY: OVERVIEW OF PD-L1 TESTING.

Published in:

Canadian Journal of Pathology, 2017, v. 9, n. 4, p. 9

By:

Downes, Michelle R.

Publication type:

Article

Pathologic features of bladder neoplasia in small bladder biopsies: A single centre retrospective review.

Published in:

Canadian Journal of Pathology, 2017, v. 9, p. 16

By:

Shivji, Sameer;
Downes, Michelle R.

Publication type:

Article

Sarcomatoid urothelial carcinoma of bladder: A retrospective single institution review.

Published in:

Canadian Journal of Pathology, 2017, v. 9, p. 10

By:

Hahn, Elan;
Downes, Michelle R.

Publication type:

Article

Hypertension caused by a renal juxtaglomerular cell tumour: A case report.

Published in:

Canadian Journal of Pathology, 2017, v. 9, p. 4

By:

Hodgson, Anjelica;
Downes, Michelle R.

Publication type:

Article

Systemic granulomas in the setting of intravesical Bacillus Camette-Guérin treatment for bladder cancer.

Published in:

Canadian Journal of Pathology, 2016, v. 8, p. 5

By:

Wong, Willard;
Downes, Michelle R.

Publication type:

Article

Medulloblastoma - An Unusual Variant of Primitive Neuroectodermal Tumour Arising in a Mature Teratoma of Testis: Case Report.

Published in:

2014

By:

Downes, Michelle R.;
van der Kwast, Theo

Publication type:

Case Study

MicroRNA-198 suppresses prostate tumorigenesis by targeting MIB1.

Published in:

Oncology Reports, 2019, v. 42, n. 3, p. 1047, doi. 10.3892/or.2019.7234

By:

Ray, Jessica;
Hoey, Christianne;
Huang, Xiaoyong;
Jeon, Jouhyun;
Taeb, Samira;
Downes, Michelle R.;
Boutros, Paul C.;
Liu, Stanley K.

Publication type:

Article

Upregulation of IFNɣ-mediated chemokines dominate the immune transcriptome of muscle-invasive urothelial carcinoma.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-021-04678-7

By:

Olkhov-Mitsel, Ekaterina;
Hodgson, Anjelica;
Liu, Stan K.;
Vesprini, Danny;
Bayani, Jane;
Bartlett, John M. S.;
Xu, Bin;
Downes, Michelle R.

Publication type:

Article

A proteomic investigation of isogenic radiation resistant prostate cancer cell lines.

Published in:

Proteomics - Clinical Applications, 2021, v. 15, n. 5, p. 1, doi. 10.1002/prca.202100037

By:

Kurganovs, Natalie;
Wang, Hanzhi;
Huang, Xiaoyong;
Ignatchenko, Vladimir;
Macklin, Andrew;
Khan, Shahbaz;
Downes, Michelle R.;
Boutros, Paul C.;
Liu, Stanley K.;
Kislinger, Thomas

Publication type:

Article

Addition of Cribriform and Intraductal Carcinoma Presence to Prostate Biopsy Reporting Strengthens Pretreatment Risk Stratification Using CAPRA and NCCN Tools.

Published in:

Clinical Genitourinary Cancer, 2024, v. 22, n. 1, p. 47, doi. 10.1016/j.clgc.2023.07.013

By:

Downes, Michelle R.;
Liu, Kristen N.;
Yanhong Yu;
Lajkosz, Katherine;
Kroon, Lisa J.;
Hollemans, Eva;
Fleshner, Neil;
Finelli, Antonio;
van Leenders, Geert J. L. H.;
Iczkowski, Kenneth A.;
van der Kwast, Theodorus H.

Publication type:

Article