Works by Downer, Eric J.

Results: 31

Tetrahydrocannabinol-induced neurotoxicity depends on CB[sub1] receptor-mediated c-Jun N-terminal kinase activation in cultured cortical neurons.

Published in:

British Journal of Pharmacology, 2003, v. 140, n. 3, p. 547, doi. 10.1038/sj.bjp.0705464

By:

Downer, Eric J.;
Fogarty, Marie P.;
Campbell, Veronica A.

Publication type:

Article

Correction to: Cycle ergometer training enhances plasma interleukin-10 in multiple sclerosis.

Published in:

2019

By:

Barry, Alison;
Cronin, Owen;
Ryan, Aisling M.;
Sweeney, Brian;
O'Toole, Orna;
O'Halloran, Ken D.;
Downer, Eric J.

Publication type:

journal article

Cycle ergometer training enhances plasma interleukin-10 in multiple sclerosis.

Published in:

2019

By:

Barry, Alison;
Cronin, Owen;
Ryan, Aisling M.;
Sweeney, Brian;
O'Toole, Orna;
O'Halloran, Ken D.;
Downer, Eric J.

Publication type:

journal article

Impact of short-term cycle ergometer training on quality of life, cognition and depressive symptomatology in multiple sclerosis patients: a pilot study.

Published in:

2018

By:

Barry, Alison;
Cronin, Owen;
Ryan, Aisling M;
Sweeney, Brian;
O'Toole, Orna;
Allen, Andrew P;
Clarke, Gerard;
O'Halloran, Ken D;
Downer, Eric J

Publication type:

journal article

CD200 Ligand--Receptor Interaction Modulates Microglial Activation In Vivo and In Vitro: A Role for IL-4.

Published in:

Journal of Neuroscience, 2007, v. 27, n. 31, p. 8309, doi. 10.1523/JNEUROSCI.1781-07.2007

By:

Lyons, Anthony;
Downer, Eric J.;
Crotty, Suzanne;
Nolan, Yvonne M.;
Mills, Kingston H. G.;
Lynch, Marina A.

Publication type:

Article

Impact of Exercise on Innate Immunity in Multiple Sclerosis Progression and Symptomatology.

Published in:

Frontiers in Physiology, 2016, p. 1, doi. 10.3389/fphys.2016.00194

By:

Barry, Alison;
Cronin, Owen;
Ryan, Aisling M.;
Sweeney, Brian;
Yap, Siew M.;
O'Toole, Orna;
Allen, Andrew P.;
Clarke, Gerard;
O'Halloran, Ken D.;
Downer, Eric J.;
Gurovich, Alvaro N.;
Fan Ye

Publication type:

Article

Phytocannabinoid‐dependent mTORC1 regulation is dependent upon inositol polyphosphate multikinase activity.

Published in:

British Journal of Pharmacology, 2021, v. 178, n. 5, p. 1149, doi. 10.1111/bph.15351

By:

Damstra‐Oddy, Joseph L.;
Warren, Eleanor C.;
Perry, Christopher J.;
Desfougères, Yann;
Fitzpatrick, John‐Mark K.;
Schaf, Judith;
Costelloe, Lisa;
Hind, William;
Downer, Eric J.;
Saiardi, Adolfo;
Williams, Robin S.B.

Publication type:

Article

The role of cannabinoids in adult neurogenesis.

Published in:

British Journal of Pharmacology, 2015, v. 172, n. 16, p. 3950, doi. 10.1111/bph.13186

By:

Prenderville, Jack A;
Kelly, Áine M;
Downer, Eric J

Publication type:

Article

High hopes for CB<sub>2</sub> receptors in neurogenesis.

Published in:

British Journal of Pharmacology, 2014, v. 171, n. 6, p. 1345, doi. 10.1111/bph.12548

By:

Downer, Eric J

Publication type:

Article

Development and Assessment of a Three‐Dimensional Tooth Morphology Quiz for Dental Students.

Published in:

Anatomical Sciences Education, 2019, v. 12, n. 3, p. 284, doi. 10.1002/ase.1815

By:

Lone, Mutahira;
Vagg, Tamara;
Theocharopoulos, Antonios;
Cryan, John F.;
Mckenna, Joseph P.;
Downer, Eric J.;
Toulouse, André

Publication type:

Article

Dok2 mediates the CD200Fc attenuation of Aβ-induced changes in glia.

Published in:

2012

By:

Lyons, Anthony;
Downer, Eric J;
Costello, Derek A;
Murphy, Niamh;
Lynch, Marina A

Publication type:

journal article

Dok2 mediates the CD200Fc attenuation of Aβ-induced changes in glia.

Published in:

Journal of Neuroinflammation, 2012, v. 9, n. 1, p. 107, doi. 10.1186/1742-2094-9-107

By:

Lyons, Anthony;
Downer, Eric J.;
Costello, Derek A.;
Murphy, Niamh;
Lynch, Marina A.

Publication type:

Article

Recent advances in the understanding of the aetiology and therapeutic strategies in burning mouth syndrome: Focus on the actions of cannabinoids.

Published in:

European Journal of Neuroscience, 2022, v. 55, n. 4, p. 1032, doi. 10.1111/ejn.14712

By:

Pereira, Sónia R.;
Tello Velasquez, Johana;
Duggan, Sarah;
Ivanisevic, Bojana;
McKenna, Joseph P.;
McCreary, Christine;
Downer, Eric J.

Publication type:

Article

Recent advances in the understanding of the aetiology and therapeutic strategies in burning mouth syndrome: Focus on the actions of cannabinoids.

Published in:

European Journal of Neuroscience, 2022, v. 55, n. 3, p. 1032, doi. 10.1111/ejn.14712

By:

Pereira, Sónia R.;
Tello Velasquez, Johana;
Duggan, Sarah;
Ivanisevic, Bojana;
McKenna, Joseph P.;
McCreary, Christine;
Downer, Eric J.

Publication type:

Article

Fractalkine-induced activation of the phosphatidylinositol-3 kinase pathway attentuates microglial activation in vivo and in vitro.

Published in:

Journal of Neurochemistry, 2009, v. 110, n. 5, p. 1547, doi. 10.1111/j.1471-4159.2009.06253.x

By:

Lyons, Anthony;
Lynch, Aileen M.;
Downer, Eric J.;
Hanley, Riona;
O'Sullivan, Joan B.;
Smith, Andrew;
Lynch, Marina A.

Publication type:

Article

A synthetic NCAM-derived mimetic peptide, FGL, exerts anti-inflammatory properties via IGF-1 and interferon-γ modulation.

Published in:

Journal of Neurochemistry, 2009, v. 109, n. 5, p. 1516, doi. 10.1111/j.1471-4159.2009.06076.x

By:

Downer, Eric J.;
Cowley, Thelma R.;
Cox, Fionnuala;
Maher, Francis O.;
Berezin, Vladimir;
Bock, Elisabeth;
Lynch, Marina A.

Publication type:

Article

Identifying Early Inflammatory Changes in Monocyte-Derived Macrophages from a Population with IQ-Discrepant Episodic Memory

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063194

By:

Downer, Eric J.;
Jones, Raasay S.;
McDonald, Claire L.;
Greco, Eleonora;
Brennan, Sabina;
Connor, Thomas J.;
Robertson, Ian H.;
Lynch, Marina A.

Publication type:

Article

Assessment of Thiel-Embalmed Cadavers as a Teaching Tool for Oral Anatomy and Local Anesthesia.

Published in:

2017

By:

Lone, Mutahira;
McKenna, Joseph P.;
Balta, Joy Y.;
O'Mahony, Siobhain M.;
Cryan, John F.;
Downer, Eric J.;
Toulouse, André

Publication type:

journal article

Neurologists' perspectives of cannabis-based medicines: results from an all-Ireland survey.

Published in:

Irish Journal of Medical Science, 2025, v. 194, n. 2, p. 687, doi. 10.1007/s11845-025-03880-0

By:

Savio, Michael;
Kearney, Hugh;
Downer, Eric J.

Publication type:

Article

Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: relevance to therapeutic effects in multiple sclerosis.

Published in:

Frontiers in Cellular Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fncel.2015.00284

By:

Crowley, Tadhg;
Fitzpatrick, John-Mark;
Kuijper, Teun;
Cryan, John F.;
O'Toole, Orna;
O'Leary, Olivia F.;
Downer, Eric J.

Publication type:

Article

CD200Fc fusion protein alleviates beta amyloid-induced glial-activation and neurodegeneration in vitro and in vivo

Published in:

2009

By:

Cowley, Thelma R.;
Miller, Anne-Marie;
Piazza, Alessia;
Downer, Eric J.;
Lynch, Marina A.

Publication type:

Abstract

Botanically-Derived Δ 9 -Tetrahydrocannabinol and Cannabidiol, and Their 1:1 Combination, Modulate Toll-like Receptor 3 and 4 Signalling in Immune Cells from People with Multiple Sclerosis.

Published in:

Molecules, 2022, v. 27, n. 6, p. 1763, doi. 10.3390/molecules27061763

By:

Fitzpatrick, John-Mark;
Hackett, Becky;
Costelloe, Lisa;
Hind, William;
Downer, Eric J.

Publication type:

Article

Role of Cannabinoids in Inflammation.

Published in:

Molecules, 2022, v. 27, n. 2, p. 478, doi. 10.3390/molecules27020478

By:

Downer, Eric J.

Publication type:

Article

A Critical Review of the Role of the Cannabinoid Compounds Δ 9 -Tetrahydrocannabinol (Δ 9 -THC) and Cannabidiol (CBD) and their Combination in Multiple Sclerosis Treatment.

Published in:

Molecules, 2020, v. 25, n. 21, p. 4930, doi. 10.3390/molecules25214930

By:

Jones, Éamon;
Vlachou, Styliani;
Downer, Eric J.

Publication type:

Article

Cannabinoids in the Pathophysiology of Skin Inflammation.

Published in:

Molecules, 2020, v. 25, n. 3, p. 652, doi. 10.3390/molecules25030652

By:

Scheau, Cristian;
Badarau, Ioana Anca;
Mihai, Livia-Gratiela;
Scheau, Andreea-Elena;
Costache, Daniel Octavian;
Constantin, Carolina;
Calina, Daniela;
Caruntu, Constantin;
Costache, Raluca Simona;
Caruntu, Ana;
Downer, Eric J.

Publication type:

Article

Abnormal Cannabidiol Affects Production of Pro-Inflammatory Mediators and Astrocyte Wound Closure in Primary Astrocytic-Microglial Cocultures.

Published in:

Molecules, 2020, v. 25, n. 3, p. 496, doi. 10.3390/molecules25030496

By:

Cardinal von Widdern, Julian;
Hohmann, Tim;
Dehghani, Faramarz;
Downer, Eric J.

Publication type:

Article

Microglial Phenotypes and Their Relationship to the Cannabinoid System: Therapeutic Implications for Parkinson's Disease.

Published in:

Molecules, 2020, v. 25, n. 3, p. 453, doi. 10.3390/molecules25030453

By:

Kelly, Rachel;
Joers, Valerie;
Tansey, Malú G.;
McKernan, Declan P.;
Dowd, Eilís;
Downer, Eric J.

Publication type:

Article

Involvement of CB2 Receptors in the Neurobehavioral Effects of Catha Edulis (Vahl) Endl. (Khat) in Mice.

Published in:

Molecules, 2019, v. 24, n. 17, p. 3164, doi. 10.3390/molecules24173164

By:

Geresu, Berhanu;
Canseco-Alba, Ana;
Sanabria, Branden;
Lin, Zhicheng;
Liu, Qing-Rong;
Onaivi, Emmanuel S.;
Engidawork, Ephrem;
Downer, Eric J.

Publication type:

Article

Plasma N-acylethanolamine and endocannabinoid levels in burning mouth syndrome: Potential role in disease pathogenesis.

Published in:

2018

By:

Barry, Alison;
O'Halloran, Ken D.;
McKenna, Joseph P.;
McCreary, Christine;
Harhen, Brendan;
Kerr, Daniel M.;
Finn, David P.;
Downer, Eric J.;
O'Halloran, Ken D

Publication type:

journal article

Plasma IL-8 signature correlates with pain and depressive symptomatology in patients with burning mouth syndrome: Results from a pilot study.

Published in:

2018

By:

Barry, Alison;
O'Halloran, Ken D.;
McKenna, Joseph P.;
McCreary, Christine;
Downer, Eric J.;
O'Halloran, Ken D

Publication type:

journal article

Phytocannabinoids, CNS cells and development: A dead issue?

Published in:

Drug & Alcohol Review, 2010, v. 29, n. 1, p. 91, doi. 10.1111/j.1465-3362.2009.00102.x

By:

DOWNER, ERIC J.;
CAMPBELL, VERONICA A.

Publication type:

Article