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Golexanolone reduces glial activation in the striatum and improves non-motor and some motor alterations in a rat model of Parkinson's disease.
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- Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1417938
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- Article
Neuroinflammation alters GABAergic neurotransmission in hyperammonemia and hepatic encephalopathy, leading to motor incoordination. Mechanisms and therapeutic implications.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1358323
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- Article
Golexanolone improves fatigue, motor incoordination and gait and memory in rats with bile duct ligation.
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- Liver International, 2024, v. 44, n. 2, p. 433, doi. 10.1111/liv.15782
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- Article
Extra-Synaptic GABA A Receptor Potentiation and Neurosteroid-Induced Learning Deficits Are Inhibited by GR3027, a GABA A Modulating Steroid Antagonist.
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- Biomolecules (2218-273X), 2023, v. 13, n. 10, p. 1496, doi. 10.3390/biom13101496
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- Article
The GABA system, a new target for medications against cognitive impairment—Associated with neuroactive steroids.
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- Journal of Internal Medicine, 2023, v. 294, n. 3, p. 281, doi. 10.1111/joim.13705
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- Article
Neurosteroid Activation of GABA-A Receptors: A Potential Treatment Target for Symptoms in Primary Biliary Cholangitis?
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- Canadian Journal of Gastroenterology & Hepatology, 2022, v. 2022, p. 1, doi. 10.1155/2022/3618090
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- Article
Golexanolone, a GABA<sub>A</sub> receptor modulating steroid antagonist, restores motor coordination and cognitive function in hyperammonemic rats by dual effects on peripheral inflammation and neuroinflammation.
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- CNS Neuroscience & Therapeutics, 2022, v. 28, n. 11, p. 1861, doi. 10.1111/cns.13926
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- Article
GR3027 reversal of neurosteroid-induced, GABA-A receptor-mediated inhibition of human brain function: an allopregnanolone challenge study.
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- Psychopharmacology, 2018, v. 235, n. 5, p. 1533, doi. 10.1007/s00213-018-4864-1
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Baculovirus-mediated gene transfer and recombinant protein expression do not interfere with insulin dependent phosphorylation of PKB/Akt in human SHSY-5Y and C3A cells.
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- BMC Cell Biology, 2007, v. 8, p. 6, doi. 10.1186/1471-2121-8-6
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- Article
Cell Cycle Progression in Serum-Free Cultures of Sf9 Insect Cells: Modulation by Conditioned Medium Factors and Implications for Proliferation and Productivity.
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- Biotechnology Progress, 2000, v. 16, n. 5, p. 837, doi. 10.1021/bp000108i
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- Article
Elevated glutamate dehydrogenase flux in glucose-deprived hybridoma and myeloma cells: Evidence from <sup>1</sup>H/<sup>15</sup>N NMR.
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- Biotechnology & Bioengineering, 1998, v. 60, n. 4, p. 508, doi. 10.1002/(SICI)1097-0290(19981120)60:4<508::AID-BIT13>3.0.CO;2-D
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- Article