Works matching AU Dorling, Leila

Results: 14

Rare germline copy number variants (CNVs) and breast cancer risk.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-021-02990-6

By:

Dennis, Joe;
Tyrer, Jonathan P.;
Walker, Logan C.;
Michailidou, Kyriaki;
Dorling, Leila;
Bolla, Manjeet K.;
Wang, Qin;
Ahearn, Thomas U.;
Andrulis, Irene L.;
Anton-Culver, Hoda;
Antonenkova, Natalia N.;
Arndt, Volker;
Aronson, Kristan J.;
Freeman, Laura E. Beane;
Beckmann, Matthias W.;
Behrens, Sabine;
Benitez, Javier;
Bermisheva, Marina;
Bogdanova, Natalia V.;
Bojesen, Stig E.

Publication type:

Article

Large-scale meta–genome-wide association study reveals common genetic factors linked to radiation-induced acute toxicities across cancer types.

Published in:

JNCI Cancer Spectrum, 2023, v. 7, n. 6, p. 1, doi. 10.1093/jncics/pkad088

By:

Naderi, Elnaz;
Aguado-Barrera, Miguel E;
Schack, Line M H;
Dorling, Leila;
Rattay, Tim;
Fachal, Laura;
Summersgill, Holly;
Martínez-Calvo, Laura;
Welsh, Ceilidh;
Dudding, Tom;
Odding, Yasmin;
Varela-Pazos, Ana;
Jena, Rajesh;
Thomson, David J;
Steenbakkers, Roel J H M;
Dennis, Joe;
Lobato-Busto, Ramón;
Alsner, Jan;
Ness, Andy;
Nutting, Chris

Publication type:

Article

A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24.1.

Published in:

Nature Genetics, 2014, v. 46, n. 8, p. 891, doi. 10.1038/ng.3020

By:

Fachal, Laura;
Gómez-Caamaño, Antonio;
Barnett, Gillian C;
Peleteiro, Paula;
Carballo, Ana M;
Calvo-Crespo, Patricia;
Kerns, Sarah L;
Sánchez-García, Manuel;
Lobato-Busto, Ramón;
Dorling, Leila;
Elliott, Rebecca M;
Dearnaley, David P;
Sydes, Matthew R;
Hall, Emma;
Burnet, Neil G;
Carracedo, Ángel;
Rosenstein, Barry S;
West, Catharine M L;
Dunning, Alison M;
Vega, Ana

Publication type:

Article

Multi-gene panel testing and association analysis in Cypriot breast cancer cases and controls.

Published in:

Frontiers in Genetics, 2023, p. 1, doi. 10.3389/fgene.2023.1248492

By:

Zanti, Maria;
Loizidou, Maria A.;
O'Mahony, Denise G.;
Dorling, Leila;
Dennis, Joe;
Devilee, Peter;
Easton, Douglas F.;
Panayiotidis, Mihalis I.;
Hadjisavvas, Andreas;
Michailidou, Kyriaki

Publication type:

Article

Radiogenomics Consortium Genome-Wide Association Study Meta-Analysis of Late Toxicity After Prostate Cancer Radiotherapy.

Published in:

2020

By:

Kerns, Sarah L;
Fachal, Laura;
Dorling, Leila;
Barnett, Gillian C;
Baran, Andrea;
Peterson, Derick R;
Hollenberg, Michelle;
Hao, Ke;
Narzo, Antonio Di;
Ahsen, Mehmet Eren;
Pandey, Gaurav;
Bentzen, Søren M;
Janelsins, Michelle;
Elliott, Rebecca M;
Pharoah, Paul D P;
Burnet, Neil G;
Dearnaley, David P;
Gulliford, Sarah L;
Hall, Emma;
Sydes, Matthew R

Publication type:

journal article

Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort.

Published in:

International Journal of Cancer, 2019, v. 144, n. 5, p. 1195, doi. 10.1002/ijc.31841

By:

Li, Jingmei;
Wen, Wei Xiong;
Eklund, Martin;
Kvist, Anders;
Eriksson, Mikael;
Christensen, Helene Nordahl;
Torstensson, Astrid;
Bajalica‐Lagercrantz, Svetlana;
Dunning, Alison M.;
Decker, Brennan;
Allen, Jamie;
Luccarini, Craig;
Pooley, Karen;
Simard, Jacques;
Dorling, Leila;
Easton, Douglas F.;
Teo, Soo‐Hwang;
Hall, Per;
Borg, Åke;
Grönberg, Henrik

Publication type:

Article

Breast cancer risks associated with missense variants in breast cancer susceptibility genes.

Published in:

Genome Medicine, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13073-022-01052-8

By:

Dorling, Leila;
Carvalho, Sara;
Allen, Jamie;
Parsons, Michael T.;
Fortuno, Cristina;
González-Neira, Anna;
Heijl, Stephan M.;
Adank, Muriel A.;
Ahearn, Thomas U.;
Andrulis, Irene L.;
Auvinen, Päivi;
Becher, Heiko;
Beckmann, Matthias W.;
Behrens, Sabine;
Bermisheva, Marina;
Bogdanova, Natalia V.;
Bojesen, Stig E.;
Bolla, Manjeet K.;
Bremer, Michael;
Briceno, Ignacio

Publication type:

Article

The Relationship between Common Genetic Markers of Breast Cancer Risk and Chemotherapy-Induced Toxicity: A Case-Control Study.

Published in:

PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0158984

By:

Dorling, Leila;
Kar, Siddhartha;
Michailidou, Kyriaki;
Hiller, Louise;
Vallier, Anne-Laure;
Ingle, Susan;
Hardy, Richard;
Bowden, Sarah J.;
Dunn, Janet A.;
Twelves, Chris;
Poole, Christopher J.;
Caldas, Carlos;
Earl, Helena M.;
Pharoah, Paul D. P.;
Abraham, Jean E.

Publication type:

Article

Splicing predictions, minigene analyses, and ACMG‐AMP clinical classification of 42 germline PALB2 splice‐site variants.

Published in:

Journal of Pathology, 2022, v. 256, n. 3, p. 321, doi. 10.1002/path.5839

By:

Valenzuela‐Palomo, Alberto;
Bueno‐Martínez, Elena;
Sanoguera‐Miralles, Lara;
Lorca, Víctor;
Fraile‐Bethencourt, Eugenia;
Esteban‐Sánchez, Ada;
Gómez‐Barrero, Susana;
Carvalho, Sara;
Allen, Jamie;
García‐Álvarez, Alicia;
Pérez‐Segura, Pedro;
Dorling, Leila;
Easton, Douglas F;
Devilee, Peter;
Vreeswijk, Maaike PG;
de la Hoya, Miguel;
Velasco, Eladio A

Publication type:

Article

A nested cohort study of 6,248 early breast cancer patients treated in neoadjuvant and adjuvant chemotherapy trials investigating the prognostic value of chemotherapy-related toxicities.

Published in:

2015

By:

Abraham, Jean E.;
Hiller, Louise;
Dorling, Leila;
Vallier, Anne-Laure;
Dunn, Janet;
Bowden, Sarah;
Ingle, Susan;
Jones, Linda;
Hardy, Richard;
Twelves, Christopher;
Poole, Christopher J.;
Pharoah, Paul D. P.;
Caldas, Carlos;
Earl, Helena M.

Publication type:

journal article

Hereditary breast and ovarian cancer: successful systematic implementation of a group approach to genetic counselling.

Published in:

Familial Cancer, 2017, v. 16, n. 1, p. 51, doi. 10.1007/s10689-016-9929-x

By:

Benusiglio, Patrick;
Maria, Marina;
Dorling, Leila;
Jouinot, Anne;
Poli, Antoine;
Villebasse, Sophie;
Le Mentec, Marine;
Claret, Béatrice;
Boinon, Diane;
Caron, Olivier

Publication type:

Article

A genome-wide association study of radiotherapy induced toxicity in head and neck cancer patients identifies a susceptibility locus associated with mucositis.

Published in:

British Journal of Cancer, 2022, v. 126, n. 7, p. 1082, doi. 10.1038/s41416-021-01670-w

By:

Schack, Line M. H.;
Naderi, Elnaz;
Fachal, Laura;
Dorling, Leila;
Luccarini, Craig;
Dunning, Alison M.;
The Head and Neck Group of the Radiogenomics Consortium;
Barnett, Gill;
Barrera, Miguel Elías Aguado;
Burnet, Neil G.;
Calvo, Laura M.;
Diergaarde, Brenda;
Dudding, Tom;
Dunning, Alison;
Duprez, Fréderic;
Kerns, Sarah L.;
Kiang, Melvin C. L.;
Langendijk, Hans;
Mehanna, Hisham;
Ness, Andy

Publication type:

Article

A genome-wide association study of radiotherapy induced toxicity in head and neck cancer patients identifies a susceptibility locus associated with mucositis.

Published in:

2022

By:

Schack, Line M H;
Naderi, Elnaz;
Fachal, Laura;
Dorling, Leila;
Luccarini, Craig;
Dunning, Alison M;
Head and Neck Group of the Radiogenomics Consortium;
Danish Head and Neck Cancer Group (DAHANCA);
Ong, Enya H W;
Chua, Melvin L K;
Langendijk, Johannes A;
Alizadeh, Behrooz Z;
Overgaard, Jens;
Eriksen, Jesper Grau;
Andreassen, Christian Nicolaj;
Alsner, Jan

Publication type:

journal article

Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity.

Published in:

2016

By:

Ahmed, Mahbubl;
Dorling, Leila;
Kerns, Sarah;
Fachal, Laura;
Elliott, Rebecca;
Partliament, Matt;
Rosenstein, Barry S;
Vega, Ana;
Gómez-Caamaño, Antonio;
Barnett, Gill;
Dearnaley, David P;
Hall, Emma;
Sydes, Matt;
Burnet, Neil;
Pharoah, Paul D P;
Eeles, Ros;
West, Catharine M L;
Gómez-Caamaño, Antonio

Publication type:

journal article