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The Impact of the Cellular Environment and Aging on Modeling Alzheimer's Disease in 3D Cell Culture Models.
- Published in:
- Advanced Science, 2023, v. 10, n. 8, p. 1, doi. 10.1002/advs.202205037
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- Publication type:
- Article
A three-dimensional human neural cell culture model of Alzheimer's disease.
- Published in:
- Nature, 2014, v. 515, n. 7526, p. 274, doi. 10.1038/nature13800
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- Publication type:
- Article
Amyloid-β42/40 ratio drives tau pathology in 3D human neural cell culture models of Alzheimer's disease.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15120-3
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- Article
Alzheimer's in 3D culture: Challenges and perspectives.
- Published in:
- BioEssays, 2015, v. 37, n. 10, p. 1139, doi. 10.1002/bies.201500063
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- Publication type:
- Article
γ-Secretase modulators reduce endogenous amyloid β<sub>42</sub> levels in human neural progenitor cells without altering neuronal differentiation.
- Published in:
- FASEB Journal, 2015, v. 29, n. 8, p. 3335, doi. 10.1096/fj.15-271015
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- Publication type:
- Article
BACE1 and presenilin/γ-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels.
- Published in:
- FASEB Journal, 2013, v. 27, n. 6, p. 2458, doi. 10.1096/fj.12-214056
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- Publication type:
- Article
Presenilin/ϒ-secretase activity regulates protein clearance from the endocytic recycling compartment.
- Published in:
- FASEB Journal, 2006, v. 20, n. 8, p. 1176, doi. 10.1096/fj.05-5531fje
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- Article
Microglial dysfunction as a key pathological change in adrenomyeloneuropathy.
- Published in:
- 2017
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- Publication type:
- journal article
Evaluation of bumetanide as a potential therapeutic agent for Alzheimer's disease.
- Published in:
- Frontiers in Pharmacology, 2023, v. 14, p. 01, doi. 10.3389/fphar.2023.1190402
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- Publication type:
- Article
Three‐Dimensional Models of the Human Brain Development and Diseases.
- Published in:
- Advanced Healthcare Materials, 2018, v. 7, n. 1, p. 1, doi. 10.1002/adhm.201700723
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- Publication type:
- Article
Neurotechnological Approaches to the Diagnosis and Treatment of Alzheimer's Disease.
- Published in:
- Frontiers in Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnins.2022.854992
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- Publication type:
- Article
Systems analysis of Alzheimer's disease pathway dysregulation in human subjects is recapitulated in 3d cellular models to reveal P38 MAPK as a therapeutic target that mitigates tau pathology.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.063716
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- Publication type:
- Article
O2‐12‐02: A NOVEL LYSOSOME TO MITOCHONDRIA SIGNALING PATHWAY REGULATES MITOCHONDRIAL ACTIVITY AND IS DISRUPTED BY AMYLOID‐β OLIGOMERS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P650, doi. 10.1016/j.jalz.2018.06.2707
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- Publication type:
- Article
A NOVEL DRUG-SCREENING PLATFORM IN MICROGLIAL CELLS IDENTIFIES POTENTIAL AD DRUGS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1485, doi. 10.1016/j.jalz.2017.07.564
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- Publication type:
- Article
RECONSTRUCTING ALZHEIMER AMYLOID AND TAU PATHOLOGY IN 3D CELL CULTURES FROM STEM CELLS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P268, doi. 10.1016/j.jalz.2016.06.485
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- Publication type:
- Article
Massachusetts Alzheimer's Disease Research Center: Progress and challenges.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 10, p. 1241, doi. 10.1016/j.jalz.2015.06.1887
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- Publication type:
- Article
Blood–Brain Barrier Dysfunction in a 3D In Vitro Model of Alzheimer's Disease.
- Published in:
- Advanced Science, 2019, v. 6, n. 20, p. N.PAG, doi. 10.1002/advs.201900962
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- Publication type:
- Article
Effects of Amyloid Beta (Aβ) Oligomers on Blood–Brain Barrier Using a 3D Microfluidic Vasculature-on-a-Chip Model.
- Published in:
- Applied Sciences (2076-3417), 2024, v. 14, n. 9, p. 3917, doi. 10.3390/app14093917
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- Publication type:
- Article
BACE1 regulates voltage-gated sodium channels and neuronal activity.
- Published in:
- Nature Cell Biology, 2007, v. 9, n. 7, p. 755, doi. 10.1038/ncb1602
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- Publication type:
- Article
A 3D human neural cell culture system for modeling Alzheimer’s disease.
- Published in:
- Nature Protocols, 2015, v. 10, n. 7, p. 1, doi. 10.1038/nprot.2015.065
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- Publication type:
- Article
3D culture models of Alzheimer's disease: a road map to a "cure-in-a-dish".
- Published in:
- Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0139-7
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- Publication type:
- Article
BACE1 activity regulates cell surface contactin-2 levels.
- Published in:
- Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-4
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- Publication type:
- Article
Identification of BACE1 cleavage sites in human voltage-gated sodium channel beta 2 subunit.
- Published in:
- Molecular Neurodegeneration, 2010, v. 5, p. 61, doi. 10.1186/1750-1326-5-61
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- Publication type:
- Article
The E280A Presenilin Mutation Reduces Voltage-Gated Sodium Channel Levels in Neuronal Cells.
- Published in:
- Neurodegenerative Diseases, 2014, v. 13, n. 2/3, p. 64, doi. 10.1159/000354669
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- Publication type:
- Article
A novel lysosome‐to‐mitochondria signaling pathway disrupted by amyloid‐β oligomers.
- Published in:
- EMBO Journal, 2018, v. 37, n. 22, p. N.PAG, doi. 10.15252/embj.2018100241
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- Publication type:
- Article