Works by Donohoe, Timothy J.

Results: 74

Alcohols as Efficient Intermolecular Initiators for a Highly Stereoselective Polyene Cyclisation Cascade.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 13, p. 1, doi. 10.1002/chem.202203732

By:

Aynetdinova, Daniya;
Jacques, Reece;
Christensen, Kirsten E.;
Donohoe, Timothy J.

Publication type:

Article

A Vicinal Diol Approach for the Total Synthesis of Molestin E, ent‐Sinulacembranolide A and ent‐Sinumaximol A.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 63, p. 1, doi. 10.1002/chem.202202464

By:

Hoff, Oskar;
Kratena, Nicolas;
Aynetdinova, Daniya;
Christensen, Kirsten E.;
Donohoe, Timothy J.

Publication type:

Article

Rücktitelbild: Rhodium-Catalyzed Ketone Methylation Using Methanol Under Mild Conditions: Formation of α-Branched Products (Angew. Chem. 3/2014).

Published in:

Angewandte Chemie, 2014, v. 126, n. 3, p. 908, doi. 10.1002/ange.201310758

By:

Chan, Louis K. M.;
Poole, Darren L.;
Shen, Di;
Healy, Mark P.;
Donohoe, Timothy J.

Publication type:

Article

Rhodium-Catalyzed Ketone Methylation Using Methanol Under Mild Conditions: Formation of α-Branched Products.

Published in:

Angewandte Chemie, 2014, v. 126, n. 3, p. 780, doi. 10.1002/ange.201307950

By:

Chan, Louis K. M.;
Poole, Darren L.;
Shen, Di;
Healy, Mark P.;
Donohoe, Timothy J.

Publication type:

Article

Interplay of Cascade Oxidative Cyclization and Hydride Shifts in the Synthesis of the ABC Spiroketal Ring System of Pectenotoxin-4.

Published in:

Angewandte Chemie, 2013, v. 125, n. 9, p. 2551, doi. 10.1002/ange.201208919

By:

Donohoe, Timothy J.;
Lipiński, Radosław M.

Publication type:

Article

Amino Acid-Based Reoxidants for Aminohydroxylation: Application to the Construction of Amino Acid-Amino Alcohol Conjugates.

Published in:

Angewandte Chemie, 2011, v. 123, n. 46, p. 11149, doi. 10.1002/ange.201103293

By:

Donohoe, Timothy J.;
Callens, Cedric K. A.;
Flores, Aida;
Mesch, Stefanie;
Poole, Darren L.;
Roslan, Ishmael A.

Publication type:

Article

A Short and Efficient Synthesis of Neodysiherbaine A by Using Catalytic Oxidative Cyclization.

Published in:

Angewandte Chemie, 2011, v. 123, n. 33, p. 7746, doi. 10.1002/ange.201102525

By:

Donohoe, Timothy J.;
Winship, Paul C. M.;
Tatton, Matthew R.;
Szeto, Peter

Publication type:

Article

Ringschlussmetathese: ein Schlüssel zur Arensynthese.

Published in:

Angewandte Chemie, 2006, v. 118, n. 17, p. 2730, doi. 10.1002/ange.200503512

By:

Timothy J. Donohoe;
Allan J. Orr;
Matilda Bingham

Publication type:

Article

Oxidative Cyclization of Diols Derived from 1,5-Dienes: Formation of Enantiopure cis-Tetrahydrofurans by Using Catalytic Osmium Tetroxide; Formal Synthesis of (+)-cis-SolaminWe thank the EPSRC and Merck for supporting this project. AstraZeneca, Pfizer, Novartis, and Merck are thanked for unrestricted funding. R. C. D. Brown is thanked for providing the NMR spectra of compound 19.

Published in:

Angewandte Chemie, 2005, v. 117, n. 30, p. 4844, doi. 10.1002/ange.200500513

By:

Timothy J. Donohoe;
Sam Butterworth

Publication type:

Article

Redox Reorganization: Aluminium Promoted 1,5‐Hydride Shifts Allow the Controlled Synthesis of Multisubstituted Cyclohexenes.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 36, p. 1, doi. 10.1002/anie.202307424

By:

Smith, Lewis B.;
Armstrong, Roly J.;
Hou, Jingyan;
Smith, Edward;
Sze, Ming;
Sterling, Alistair J.;
Smith, Alex;
Duarte, Fernanda;
Donohoe, Timothy J.

Publication type:

Article

Alcohols as Alkylating Agents in the Cation‐Induced Formation of Nitrogen Heterocycles.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 34, p. 1, doi. 10.1002/anie.202206800

By:

Cox, Lydia;
Zhu, Yuxiang;
Smith, Philip J.;
Christensen, Kirsten E.;
Sidera Portela, Mireia;
Donohoe, Timothy J.

Publication type:

Article

Evolution of the Dearomative Functionalization of Activated Quinolines and Isoquinolines: Expansion of the Electrophile Scope.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 27, p. 1, doi. 10.1002/anie.202204682

By:

Kischkewitz, Marvin;
Marinic, Bruno;
Kratena, Nicolas;
Lai, Yonglin;
Hepburn, Hamish B.;
Dow, Mark;
Christensen, Kirsten E.;
Donohoe, Timothy J.

Publication type:

Article

Hydrogen‐Borrowing Alkylation of 1,2‐Amino Alcohols in the Synthesis of Enantioenriched γ‐Aminobutyric Acids.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 13, p. 6981, doi. 10.1002/anie.202100922

By:

Hall, Christopher J. J.;
Goundry, William R. F.;
Donohoe, Timothy J.

Publication type:

Article

A Vinyl Cyclopropane Ring Expansion and Iridium‐Catalyzed Hydrogen Borrowing Cascade.

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 28, p. 11339, doi. 10.1002/anie.202003614

By:

Wübbolt, Simon;
Cheong, Choon Boon;
Frost, James R.;
Christensen, Kirsten E.;
Donohoe, Timothy J.

Publication type:

Article

Transition‐Metal‐Free Reductive Hydroxymethylation of Isoquinolines.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 44, p. 15697, doi. 10.1002/anie.201908857

By:

Reeves, Benjamin M.;
Hepburn, Hamish B.;
Grozavu, Alexandru;
Lindsay‐Scott, Peter J.;
Donohoe, Timothy J.

Publication type:

Article

Catalytic Asymmetric Synthesis of Cyclohexanes by Hydrogen Borrowing Annulations.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 36, p. 12558, doi. 10.1002/anie.201907514

By:

Armstrong, Roly J.;
Akhtar, Wasim M.;
Young, Tom A.;
Duarte, Fernanda;
Donohoe, Timothy J.

Publication type:

Article

An Efficient Synthesis of Lactacystin β-Lactone ( We thank the EPSRC and GlaxoSmithKline for funding this project. AstraZeneca, Pfizer, and Novartis are thanked for generous unrestricted funding. ).

Published in:

Angewandte Chemie, 2004, v. 116, n. 17, p. 2343, doi. 10.1002/ange.200453843

By:

Timothy J. Donohoe;
Herman O. Sintim;
Leena Sisangia;
John D. Harling

Publication type:

Article

Synthesis and Phytotoxic Activity of New Pyridones Derived from 4-Hydroxy-6-Methylpyridin-2(1H)-one.

Published in:

Molecules, 2009, v. 14, n. 12, p. 4973, doi. 10.3390/molecules14124973

By:

Demuner, Antonio Jacinto;
Valente, Vania Maria Moreira;
Barbosa, Luiz Cláudio Almeida;
Rathi, Akshat H.;
Donohoe, Timothy J.;
Thompson, Amber L.

Publication type:

Article

Tethered Aminohydroxylation Reaction and Its Application to Total Synthesis.

Published in:

European Journal of Organic Chemistry, 2012, v. 2012, n. 4, p. 655, doi. 10.1002/ejoc.201101464

By:

Donohoe, Timothy J.;
Callens, Cedric K. A.;
Lacy, Adam R.;
Winter, Christian

Publication type:

Article

Tethered Aminohydroxylation Reaction and Its Application to Total Synthesis (Eur. J. Org. Chem. 4/2012).

Published in:

European Journal of Organic Chemistry, 2012, v. 2012, n. 4, p. n/a, doi. 10.1002/ejoc.201290003

By:

Donohoe, Timothy J.;
Callens, Cedric K. A.;
Lacy, Adam R.;
Winter, Christian

Publication type:

Article

Functional group tolerant hydrogen borrowing C-alkylation.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49249-2

By:

Bailey, Elliot P.;
Donohoe, Timothy J.;
Smith, Martin D.

Publication type:

Article

Cobalt versus Osmium: Control of Both trans and cis Selectivity in Construction of the EFG Rings of Pectenotoxin 4.

Published in:

Angewandte Chemie International Edition, 2017, v. 56, n. 47, p. 14883, doi. 10.1002/anie.201708278

By:

Roushanbakhti, Ahria;
Liu, Yifan;
Winship, Paul C. M.;
Tucker, Michael J.;
Akhtar, Wasim M.;
Walter, Daryl S.;
Wrigley, Gail;
Donohoe, Timothy J.

Publication type:

Article

Dehydromicrosclerodermin B and Microsclerodermin J: Total Synthesis and Structural Revision.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 33, p. 9753, doi. 10.1002/anie.201604764

By:

Melikhova, Ekaterina Y.;
Pullin, Robert D. C.;
Winter, Christian;
Donohoe, Timothy J.

Publication type:

Article

Catalytic Hypervalent Iodine Promoters Lead to Styrene Dimerization and the Formation of Tri- and Tetrasubstituted Cyclobutanes.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 15, p. 4748, doi. 10.1002/anie.201511683

By:

Colomer, Ignacio;
Coura Barcelos, Rosimeire;
Donohoe, Timothy J.

Publication type:

Article

Hydrogen-Borrowing and Interrupted-Hydrogen-Borrowing Reactions of Ketones and Methanol Catalyzed by Iridium.

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 5, p. 1642, doi. 10.1002/anie.201410391

By:

Shen, Di;
Poole, Darren L.;
Shotton, Camilla C.;
Kornahrens, Anne F.;
Donohoe, Timothy J.;
Healy, Mark P.

Publication type:

Article

Short and Efficient Syntheses of Protoberberine Alkaloids using Palladium-Catalyzed Enolate Arylation.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 52, p. 14555, doi. 10.1002/anie.201409164

By:

Gatland, Alice E.;
Pilgrim, Ben S.;
Procopiou, Panayiotis A.;
Donohoe, Timothy J.

Publication type:

Article

Back Cover: Rhodium-Catalyzed Ketone Methylation Using Methanol Under Mild Conditions: Formation of α-Branched Products (Angew. Chem. Int. Ed. 3/2014).

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 3, p. 892, doi. 10.1002/anie.201310758

By:

Chan, Louis K. M.;
Poole, Darren L.;
Shen, Di;
Healy, Mark P.;
Donohoe, Timothy J.

Publication type:

Article

Rhodium-Catalyzed Ketone Methylation Using Methanol Under Mild Conditions: Formation of α-Branched Products.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 3, p. 761, doi. 10.1002/anie.201307950

By:

Chan, Louis K. M.;
Poole, Darren L.;
Shen, Di;
Healy, Mark P.;
Donohoe, Timothy J.

Publication type:

Article

Utility of the Ammonia-Free Birch Reduction of Electron-Deficient Pyrroles: Total Synthesis of the 20S Proteasome Inhibitor, clasto-Lactacystin β-Lactone.

Published in:

Chemistry - A European Journal, 2005, v. 11, n. 14, p. 4227, doi. 10.1002/chem.200401119

By:

Timothy J. Donohoe;
Herman O. Sintim;
Leena Sisangia;
Karl W. Ace;
Paul M. Guyo;
Andrew Cowley;
John D. Harling

Publication type:

Article

Transition‐Metal‐Free Reductive Hydroxymethylation of Isoquinolines.

Published in:

Angewandte Chemie, 2019, v. 131, n. 44, p. 15844, doi. 10.1002/ange.201908857

By:

Reeves, Benjamin M.;
Hepburn, Hamish B.;
Grozavu, Alexandru;
Lindsay‐Scott, Peter J.;
Donohoe, Timothy J.

Publication type:

Article

Catalytic Asymmetric Synthesis of Cyclohexanes by Hydrogen Borrowing Annulations.

Published in:

Angewandte Chemie, 2019, v. 131, n. 36, p. 12688, doi. 10.1002/ange.201907514

By:

Armstrong, Roly J.;
Akhtar, Wasim M.;
Young, Tom A.;
Duarte, Fernanda;
Donohoe, Timothy J.

Publication type:

Article

Cobalt versus Osmium: Control of Both trans and cis Selectivity in Construction of the EFG Rings of Pectenotoxin 4.

Published in:

Angewandte Chemie, 2017, v. 129, n. 47, p. 15079, doi. 10.1002/ange.201708278

By:

Roushanbakhti, Ahria;
Liu, Yifan;
Winship, Paul C. M.;
Tucker, Michael J.;
Akhtar, Wasim M.;
Walter, Daryl S.;
Wrigley, Gail;
Donohoe, Timothy J.

Publication type:

Article

Dehydromicrosclerodermin B and Microsclerodermin J: Total Synthesis and Structural Revision.

Published in:

Angewandte Chemie, 2016, v. 128, n. 33, p. 9905, doi. 10.1002/ange.201604764

By:

Melikhova, Ekaterina Y.;
Pullin, Robert D. C.;
Winter, Christian;
Donohoe, Timothy J.

Publication type:

Article

Catalytic Hypervalent Iodine Promoters Lead to Styrene Dimerization and the Formation of Tri- and Tetrasubstituted Cyclobutanes.

Published in:

Angewandte Chemie, 2016, v. 128, n. 15, p. 4826, doi. 10.1002/ange.201511683

By:

Colomer, Ignacio;
Coura Barcelos, Rosimeire;
Donohoe, Timothy J.

Publication type:

Article

Hydrogen-Borrowing and Interrupted-Hydrogen-Borrowing Reactions of Ketones and Methanol Catalyzed by Iridium.

Published in:

Angewandte Chemie, 2015, v. 127, n. 5, p. 1662, doi. 10.1002/ange.201410391

By:

Di Shen;
Poole, Darren L.;
Shotton, Camilla C.;
Kornahrens, Anne F.;
Healy, Mark P;
Donohoe, Timothy J.

Publication type:

Article

Short and Efficient Syntheses of Protoberberine Alkaloids using Palladium-Catalyzed Enolate Arylation.

Published in:

Angewandte Chemie, 2014, v. 126, n. 52, p. 14783, doi. 10.1002/ange.201409164

By:

Gatland, Alice E.;
Pilgrim, Ben S.;
Procopiou, Panayiotis A.;
Donohoe, Timothy J.

Publication type:

Article

Oxidative cyclization for the synthesis of complex tetrahydrofuran-containing natural products.

Published in:

Pure & Applied Chemistry, 2013, v. 85, n. 6, p. 1175, doi. 10.1351/PAC-CON-12-10-25

By:

Pullin, Robert D. C.;
Lipiński, Radosław M.;
Donohoe, Timothy J.

Publication type:

Article

Interplay of Cascade Oxidative Cyclization and Hydride Shifts in the Synthesis of the ABC Spiroketal Ring System of Pectenotoxin-4.

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 9, p. 2491, doi. 10.1002/anie.201208919

By:

Donohoe, Timothy J.;
Lipiński, Radosław M.

Publication type:

Article

Amino Acid-Based Reoxidants for Aminohydroxylation: Application to the Construction of Amino Acid-Amino Alcohol Conjugates.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 46, p. 10957, doi. 10.1002/anie.201103293

By:

Donohoe, Timothy J.;
Callens, Cedric K. A.;
Flores, Aida;
Mesch, Stefanie;
Poole, Darren L.;
Roslan, Ishmael A.

Publication type:

Article

A Short and Efficient Synthesis of Neodysiherbaine A by Using Catalytic Oxidative Cyclization.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 33, p. 7604, doi. 10.1002/anie.201102525

By:

Donohoe, Timothy J.;
Winship, Paul C. M.;
Tatton, Matthew R.;
Szeto, Peter

Publication type:

Article

Synthesis of (−)-Hygromycin A: Application of Mitsunobu Glycosylation and Tethered Aminohydroxylation.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 35, p. 6507, doi. 10.1002/anie.200902840

By:

Donohoe, Timothy J.;
Flores, Aida;
Bataille, Carole J. R.;
Churruca, Fátima

Publication type:

Article

Ruthenium-Catalyzed Isomerization of Terminal Olefins: Applications to Synthesis.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 6, p. 1014, doi. 10.1002/anie.200804617

By:

Donohoe, Timothy J.;
O'Riordan, Timothy J. C.;
Rosa, Carla P.

Publication type:

Article

Synthesis of (−)-( Z)-Deoxypukalide.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 38, p. 7314, doi. 10.1002/anie.200802703

By:

Donohoe, Timothy J.;
Ironmonger, Alan;
Kershaw, Neil M.

Publication type:

Article

Pyridine- N-Oxide as a Mild Reoxidant Which Transforms Osmium-Catalyzed Oxidative Cyclization.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 15, p. 2872, doi. 10.1002/anie.200705425

By:

Donohoe, Timothy J.;
Wheelhouse (née Gosby), Katherine M. P.;
Lindsay-Scott, Peter J.;
Glossop, Paul A.;
Nash, Ian A.;
Parker, Jeremy S.

Publication type:

Article

Hydride Shift Generated Oxonium Ions: Evidence for Mechanism and Intramolecular Trapping Experiments to Form trans THF Derivatives.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 15, p. 2869, doi. 10.1002/anie.200705340

By:

Donohoe, Timothy J.;
Williams, Oliver;
Churchill, Gwydion H.

Publication type:

Article

Dynamic Kinetic Resolution Allows Control of Remote Stereochemistry in Asymmetric Hydrogen Borrowing Alkylation.

Published in:

Angewandte Chemie International Edition, 2025, v. 64, n. 13, p. 1, doi. 10.1002/anie.202424959

By:

Cheang, Daniella M. J.;
Crompton, Jessica L.;
Amer, Mostafa M.;
Battiti, Francisco;
Skjelstad, Bastian Bjerkem;
Christensen, Kirsten E.;
Barton, Peter;
Duarte, Fernanda;
Donohoe, Timothy J.

Publication type:

Article

Recent Developments in Methodology for the Direct Oxyamination of Olefins.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 1, p. 58, doi. 10.1002/chem.201002323

By:

Donohoe, Timothy J.;
Callens, Cedric K. A.;
Flores, Aida;
Lacy, Adam R.;
Rathi, Akshat H.

Publication type:

Article

Ring-Closing Metathesis: Novel Routes to Aromatic Heterocycles.

Published in:

Chemistry - A European Journal, 2008, v. 14, n. 19, p. 5716, doi. 10.1002/chem.200800130

By:

Donohoe, Timothy J.;
Fishlock, Lisa P.;
Procopiou, Panayiotis A.

Publication type:

Article

Dynamic Kinetic Resolution Allows Control of Remote Stereochemistry in Asymmetric Hydrogen Borrowing Alkylation.

Published in:

Angewandte Chemie, 2025, v. 137, n. 13, p. 1, doi. 10.1002/ange.202424959

By:

Cheang, Daniella M. J.;
Crompton, Jessica L.;
Amer, Mostafa M.;
Battiti, Francisco;
Skjelstad, Bastian Bjerkem;
Christensen, Kirsten E.;
Barton, Peter;
Duarte, Fernanda;
Donohoe, Timothy J.

Publication type:

Article

Hydrogen‐Borrowing‐Based Methods for the Construction of Quaternary Stereocentres.

Published in:

Angewandte Chemie, 2025, v. 137, n. 8, p. 1, doi. 10.1002/ange.202423179

By:

Crompton, Jessica L.;
Jenkins, Timothy C.;
Rowe, Sam M.;
Donohoe, Timothy J.

Publication type:

Article