Works matching AU Don, Anthony S.

Results: 27

Reduced plasma hexosylceramides in frontotemporal dementia are a biomarker of white matter integrity.

Published in:

Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2025, v. 17, n. 2, p. 1, doi. 10.1002/dad2.70131

By:

Marian, Oana C.;
Matis, Sophie;
Dobson‐Stone, Carol;
Kim, Woojin S.;
Kwok, John B.;
Piguet, Olivier;
Halliday, Glenda M.;
Landin‐Romero, Ramon;
Don, Anthony S.

Publication type:

Article

The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity.

Published in:

Nature Medicine, 2013, v. 19, n. 2, p. 232, doi. 10.1038/nm.3049

By:

Collison, Adam;
Hatchwell, Luke;
Verrills, Nicole;
Wark, Peter A B;
de Siqueira, Ana Pereira;
Tooze, Melinda;
Carpenter, Helen;
Don, Anthony S;
Morris, Jonathan C;
Zimmermann, Nives;
Bartlett, Nathan W;
Rothenberg, Marc E;
Johnston, Sebastian L;
Foster, Paul S;
Mattes, Joerg

Publication type:

Article

Deep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28889-2

By:

Montgomery, Magdalene K.;
Bayliss, Jacqueline;
Nie, Shuai;
De Nardo, William;
Keenan, Stacey N.;
Miotto, Paula M.;
Karimkhanloo, Hamzeh;
Huang, Cheng;
Schittenhelm, Ralf B.;
Don, Anthony S.;
Ryan, Andrew;
Williamson, Nicholas A.;
Ooi, Geraldine J.;
Brown, Wendy A.;
Burton, Paul R.;
Parker, Benjamin L.;
Watt, Matthew J.

Publication type:

Article

Disparate In Vivo Efficacy of FTY720 in Xenograft Models of Philadelphia Positive and Negative B-lineage Acute Lymphoblastic Leukemia.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0036429

By:

Wallington-Beddoe, Craig T.;
Don, Anthony S.;
John Hewson;
Qiao Qiao;
Papa, Rachael A.;
Lock, Richard B.;
Bradstock, Kenneth F.;
Bendall, Linda J.

Publication type:

Article

Treatment with a sphingosine analog after the inception of house dust mite-induced airway inflammation alleviates key features of experimental asthma.

Published in:

Respiratory Research, 2015, v. 16, n. 2, p. 1, doi. 10.1186/s12931-015-0180-z

By:

Gendron, David;
Lemay, Anne-Marie;
Tremblay, Claudine;
Lai, Laetitia J. A.;
Langlois, Anick;
Bernatchez, Émilie;
Flamand, Nicolas;
Blanchet, Marie-Renée;
Don, Anthony S.;
Bossé, Ynuk;
Bissonnette, Élyse;
Marsolais, David

Publication type:

Article

Treatment with a sphingosine analog after the inception of house dust mite-induced airway inflammation alleviates key features of experimental asthma.

Published in:

2015

By:

Gendron, David;
Lemay, Anne-Marie;
Tremblay, Claudine;
Lai, Laetitia Ja;
Langlois, Anick;
Bernatchez, Émilie;
Flamand, Nicolas;
Blanchet, Marie-Renée;
Don, Anthony S;
Bossé, Ynuk;
Bissonnette, Élyse;
Marsolais, David

Publication type:

journal article

Mechanism of Selectivity of an Angiogenesis Inhibitor From Screening a Genome-Wide Set of Saccharomyces cerevisiae Deletion Strains.

Published in:

JNCI: Journal of the National Cancer Institute, 2005, v. 97, n. 20, p. 1539, doi. 10.1093/jnci/dji316

By:

Dilda, Pierre J.;
Don, Anthony S.;
Tanabe, Kara M.;
Higgins, Vincent J.;
Allen, John D.;
Dawes, Ian W.;
Hogg, Philip J.

Publication type:

Article

Ablation of sphingosine kinase 2 suppresses fatty liver-associated hepatocellular carcinoma via downregulation of ceramide transfer protein.

Published in:

Oncogenesis, 2022, v. 11, n. 1, p. 1, doi. 10.1038/s41389-022-00444-0

By:

Liu, Xin Tracy;
Chung, Long Hoa;
Liu, Da;
Chen, Jinbiao;
Huang, Yu;
Teo, Jonathan D.;
Han, Xingxing Daisy;
Zhao, Yinan;
Guan, Fiona H. X.;
Tran, Collin;
Lee, Jun Yup;
Couttas, Timothy A.;
Liu, Ken;
McCaughan, Geoffery W.;
Gorrell, Mark D.;
Don, Anthony S.;
Zhang, Shubiao;
Qi, Yanfei

Publication type:

Article

Re-Configuration of Sphingolipid Metabolism by Oncogenic Transformation.

Published in:

Biomolecules (2218-273X), 2014, v. 4, n. 1, p. 315, doi. 10.3390/biom4010315

By:

Don, Anthony S.;
Xin Y. Lim;
Couttas, Timothy A.

Publication type:

Article

Modulating tone: the overture of S1P receptor immunotherapeutics.

Published in:

Immunological Reviews, 2008, v. 223, n. 1, p. 221, doi. 10.1111/j.1600-065X.2008.00645.x

By:

Rosen, Hugh;
Gonzalez-Cabrera, Pedro;
Marsolais, David;
Cahalan, Stuart;
Don, Anthony S.;
Sanna, M. Germana

Publication type:

Article

Phagocytosis of IgG-Coated Polystyrene Beads by Macrophages Induces and Requires High Membrane Order.

Published in:

Traffic, 2011, v. 12, n. 12, p. 1730, doi. 10.1111/j.1600-0854.2011.01272.x

By:

Magenau, Astrid;
Benzing, Carola;
Proschogo, Nicholas;
Don, Anthony S.;
Hejazi, Leila;
Karunakaran, Denuja;
Jessup, Wendy;
Gaus, Katharina

Publication type:

Article

Increased sphingosine 1-phosphate mediates inflammation and fibrosis in tubular injury in diabetic nephropathy.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2016, v. 43, n. 1, p. 56, doi. 10.1111/1440-1681.12494

By:

Yaghobian, Dania;
Don, Anthony S.;
Yaghobian, Sarina;
Chen, Xinming;
Pollock, Carol A.;
Saad, Sonia

Publication type:

Article

Defective Lysosomal Lipid Catabolism as a Common Pathogenic Mechanism for Dementia.

Published in:

NeuroMolecular Medicine, 2021, v. 23, n. 1, p. 1, doi. 10.1007/s12017-021-08644-4

By:

Lee, Jun Yup;
Marian, Oana C.;
Don, Anthony S.

Publication type:

Article

Correction: The major TMEM106B dementia risk allele affects TMEM106B protein levels, fibril formation, and myelin lipid homeostasis in the ageing human hippocampus.

Published in:

2024

By:

Lee, Jun Yup;
Harney, Dylan J.;
Teo, Jonathan D.;
Kwok, John B.;
Sutherland, Greg T.;
Larance, Mark;
Don, Anthony S.

Publication type:

Correction Notice

Lipidome changes in alcohol‐related brain damage.

Published in:

Journal of Neurochemistry, 2022, v. 160, n. 2, p. 271, doi. 10.1111/jnc.15530

By:

Smith, Caine C.;
Sheedy, Donna L.;
McEwen, Holly P.;
Don, Anthony S.;
Kril, Jillian J.;
Sutherland, Greg T.

Publication type:

Article

Sphingosine 1‐phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes.

Published in:

Journal of Neurochemistry, 2020, v. 153, n. 2, p. 173, doi. 10.1111/jnc.14917

By:

Tran, Collin;
Heng, Benjamin;
Teo, Jonathan D.;
Humphrey, Sean J.;
Qi, Yanfei;
Couttas, Timothy A.;
Stefen, Holly;
Brettle, Merryn;
Fath, Thomas;
Guillemin, Gilles J.;
Don, Anthony S.

Publication type:

Article

A Phosphorylatable Sphingosine Analog Induces Airway Smooth Muscle Cytostasis and Reverses Airway Hyperresponsiveness in Experimental Asthma.

Published in:

Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00078

By:

Gendron, David R.;
Lecours, Pascale B.;
Lemay, Anne-Marie;
Beaulieu, Marie-Josée;
Huppé, Carole-Ann;
Lee-Gosselin, Audrey;
Flamand, Nicolas;
Don, Anthony S.;
Bissonnette, Élyse;
Blanchet, Marie-Renée;
Laplante, Mathieu;
Bourgoin, Sylvain G.;
Bossé, Ynuk;
Marsolais, David

Publication type:

Article

Sphingosine Kinase 2 Potentiates Amyloid Deposition but Protects against Hippocampal Volume Loss and Demyelination in a Mouse Model of Alzheimer's Disease.

Published in:

Journal of Neuroscience, 2019, v. 39, n. 48, p. 9645, doi. 10.1523/JNEUROSCI.0524-19.2019

By:

Lei, Mona;
Teo, Jonathan D.;
Huitong Song;
McEwen, Holly P.;
Jun Yup Lee;
Couttas, Timothy A.;
Duncan, Thomas;
Chesworth, Rose;
Bertz, Josefine;
Przybyla, Magdalena;
Van Eersel, Janet;
Heng, Benjamin;
Guillemin, Gilles J.;
Ittner, Lars M.;
Fath, Thomas;
Garner, Brett;
Ittner, Arne;
Karl, Tim;
Don, Anthony S.

Publication type:

Article

Peroxisomal β-oxidation enzyme, DECR2, regulates lipid metabolism and promotes treatment resistance in advanced prostate cancer.

Published in:

British Journal of Cancer, 2024, v. 130, n. 5, p. 741, doi. 10.1038/s41416-023-02557-8

By:

Mah, Chui Yan;
Nguyen, An Dieu Trang;
Niijima, Takuto;
Helm, Madison;
Dehairs, Jonas;
Ryan, Feargal J.;
Ryan, Natalie;
Quek, Lake-Ee;
Hoy, Andrew J.;
Don, Anthony S.;
Mills, Ian G.;
Swinnen, Johannes V.;
Lynn, David J.;
Nassar, Zeyad D.;
Butler, Lisa M.

Publication type:

Article

ABCA8 stimulates sphingomyelin production in oligodendrocytes.

Published in:

Biochemical Journal, 2013, v. 452, n. 3, p. 401, doi. 10.1042/BJ20121764

By:

Woojin Scott KIM;
Jen-Hsiang T. HSIAO;
BHATIA, Surabhi;
GLAROS, Elias N.;
DON, Anthony S.;
TSURUOKA, Shuichi;
WEICKERT, Cynthia SHANNON;
HALLIDAY, Glenda M.

Publication type:

Article

Disrupted myelin lipid metabolism differentiates frontotemporal dementia caused by GRN and C9orf72 gene mutations.

Published in:

Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-023-01544-7

By:

Marian, Oana C.;
Teo, Jonathan D.;
Lee, Jun Yup;
Song, Huitong;
Kwok, John B.;
Landin-Romero, Ramon;
Halliday, Glenda;
Don, Anthony S.

Publication type:

Article

Mitochondrial electron transport chain, ceramide, and coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.87340

By:

Diaz-Vegas, Alexis;
Madsen, Søren;
Cooke, Kristen C.;
Carroll, Luke;
Khor, Jasmine X. Y.;
Turner, Nigel;
Lim, Xin Y.;
Astore, Miro A.;
Morris, Jonathan C.;
Don, Anthony S.;
Garfield, Amanda;
Zarini, Simona;
Berry, Karin A. Zemski;
Ryan, Andrew P.;
Bergman, Bryan C.;
Brozinick, Joseph T.;
James, David E.;
Burchfield, James G.

Publication type:

Article

Exposure to solar ultraviolet radiation establishes a novel immune suppressive lipidome in skin-draining lymph nodes.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2022.1045731

By:

Tse, Benita C. Y.;
Ferguson, Angela L.;
Yen Chin Koay;
Grau, Georges E.;
Don, Anthony S.;
Byrne, Scott N.

Publication type:

Article

A Three-Step Assay for Ceramide Synthase Activity Using a Fluorescent Substrate and HPLC.

Published in:

Lipids, 2015, v. 50, n. 1, p. 101, doi. 10.1007/s11745-014-3969-5

By:

Couttas, Timothy A.;
Lim, Xin Y.;
Don, Anthony S.

Publication type:

Article

The major TMEM106B dementia risk allele affects TMEM106B protein levels, fibril formation, and myelin lipid homeostasis in the ageing human hippocampus.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00650-3

By:

Lee, Jun Yup;
Harney, Dylan J;
Teo, Jonathan D;
Kwok, John B;
Sutherland, Greg T.;
Larance, Mark;
Don, Anthony S

Publication type:

Article

Uncoupling N-acetylaspartate from brain pathology: implications for Canavan disease gene therapy.

Published in:

Acta Neuropathologica, 2018, v. 135, n. 1, p. 95, doi. 10.1007/s00401-017-1784-9

By:

von Jonquieres, Georg;
Spencer, Ziggy H. T.;
Rowlands, Benjamin D.;
Klugmann, Claudia B.;
Bongers, Andre;
Harasta, Anne E.;
Parley, Kristina E.;
Cederholm, Jennie;
Teahan, Orla;
Pickford, Russell;
Delerue, Fabien;
Ittner, Lars M.;
Fröhlich, Dominik;
McLean, Catriona A.;
Don, Anthony S.;
Schneider, Miriam;
Housley, Gary D.;
Rae, Caroline D.;
Klugmann, Matthias

Publication type:

Article

Ceramide Regulates Anti-Tumor Mechanisms of Erianin in Androgen-Sensitive and Castration-Resistant Prostate Cancers.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.738078

By:

Trapika, I Gusti Md Gde Surya C.;
Liu, Xin Tracy;
Chung, Long Hoa;
Lai, Felcia;
Xie, Chanlu;
Zhao, Yang;
Cui, Shaohui;
Chen, Jinbiao;
Tran, Collin;
Wang, Qian;
Zhang, Shubiao;
Don, Anthony S.;
Li, George Qian;
Hanrahan, Jane R.;
Qi, Yanfei

Publication type:

Article